Histone-lysine N-methyltransferase
gene
reagent
sample publication
sample review
ASH1L
ASH1 like histone lysine methyltransferase
CLLD8
SET domain bifurcated histone lysine methyltransferase 2
total:1
Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. 2008 to the paper
Abgent anti-human SETDB2 antibody was used to perform western blot in order to study the role of lysine methylation of HIV-1 Tat in transcriptional activity of the viral LTR.
DOT1L
DOT1 like histone lysine methyltransferase
total:1
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. 2008 to the paper
Bethyl anti-DOT1L antibody (A300-954A or 953A) was used in ChIP assay to study the recruitment of DOT1L and the patterning of mono-, di-, and trimethylation of H3K79 under dynamic conditions in human HEK293T cells.
EHMT2
euchromatic histone lysine methyltransferase 2
total:3
ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes. 2010 to the paper
Upstate G9a antibody (#07-551) was used to perform ChIP assays in order to clarify that a KRAB domain-containing ZNF is involved in recruitment of the KAP1 and SETDB1 to specific regions of the human genome. more
EZH1
enhancer of zeste 1 polycomb repressive complex 2 subunit
Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
total:11
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. 2009 to the paper
Abcam anti-EZH2 was used to perform western blot in order to show the effects of G9a/KMT1C and jumonji-C type histone demethylases in histone H1 isotype 4 methylation and demethylation. more
KMT2A
lysine methyltransferase 2A
total:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 to the paper
Upstate Biotechnology anti-MLL antibody was used for coimmunoprecipitation in order to illustrate the role of c-Myb in MLL-associated leukemogenesis. more
NSD1
nuclear receptor binding SET domain protein 1
RIZ
PR/SET domain 2
total:2
RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression. 2009 to the paper
Abgent RIZ1 antibody was used to perform western blot, flow cytometry, and immunohistochemistry in order to investigate the downregulation of RIZ1 expression during progression from chronic phase to blast crisis in CML. more
Set1
SET domain containing 1A, histone lysine methyltransferase
total:1
CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. 2005 to the paper
Abgent anti-Set1 antibody was used in western blot to study the CpG-binding protein (CXXC finger protein 1) which is a component of the mammalian set1 histone H3-lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex.
SETD1B
SET domain containing 1B, histone lysine methyltransferase
SETD2
SET domain containing 2, histone lysine methyltransferase
SETD3
SET domain containing 3, actin histidine methyltransferase
SETD7
SET domain containing 7, histone lysine methyltransferase
total:5
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. 2008 to the paper
Abcam anti-H3K4me1, me2, me3 antibodies (Ab8895, Ab7766, Ab8580) were used in ChIP assay to study FoxA1 differential transcriptional activities in breast and prostate cancer cells and their functional relation with the epigenome of these cells. more
KMT5A
lysine methyltransferase 5A
total:1
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. 2008 to the paper
Abcam anti-H4K20me1, me2, me3 antibodies (Ab9051, Ab9052, and Ab9053) were used in ChIP assay to study FoxA1 differential transcriptional activities in breast and prostate cancer cells and their functional relation with the epigenome of these cells.
SETDB1
SET domain bifurcated histone lysine methyltransferase 1
total:4
The core binding factor CBF negatively regulates skeletal muscle terminal differentiation. 2010 to the paper
Upstate Biotech anti-trimethyl histone 3 lysine 9 antibody was used for chromatin immunoprecipitation in order to investigate if core binding factor was involved in the control of skeletal muscle terminal differentiation. more
SETMAR
SET domain and mariner transposase fusion gene
total:1
Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. 2008 to the paper
Abcam anti-human SETMAR antibody was used to perform western blot in order to study the role of lysine methylation of HIV-1 Tat in transcriptional activity of the viral LTR.
SUV39H1
suppressor of variegation 3-9 homolog 1
total:6
Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. 2008 to the paper
Cell Signaling anti-human SUV39H1 antibody was used to perform western blot in order to study the role of lysine methylation of HIV-1 Tat in transcriptional activity of the viral LTR. more
NSD2
nuclear receptor binding SET domain protein 2
NSD3
nuclear receptor binding SET domain protein 3