Heparan sulfate/heparin (HS-GAG) metabolism
gene
reagent
sample publication
sample review
alpha L iduronidase
alpha-L-iduronidase
total:1
Intrathecal administration of AAV vectors for the treatment of lysosomal storage in the brains of MPS I mice. 2006 to the paper
BioMarin Pharmaceutical rabbit polyclonal IDUA antibody was used in immunohistochemistry (1:3000) to determine the expression level of IDUA in the brain after AAV vectors.
B3GALT6
beta-1,3-galactosyltransferase 6
total:1
Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease. 2010 to the paper
Abnova anti-B3GALT6(M06) mouse monoclonal antibody was used to perform western blot in order to study the efficiency of using the small interfering RNA(siRNA) to control expression of particular genes involved in GAG synthesis for the treatment of mucopolysaccharidosis type III.
B4GALT7
beta-1,4-galactosyltransferase 7
total:1
Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease. 2010 to the paper
Proteintech Group anti-B4GALT7 rabbit polyclonal antibody was used to perform western blot in order to study the efficiency of using the small interfering RNA(siRNA) to control expression of particular genes involved in GAG synthesis for the treatment of mucopolysaccharidosis type III.
CD57
beta-1,3-glucuronyltransferase 1
total:9
Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival. 2008 to the paper
Becton Dickinson anti-CD57 antibody was used in immunohistochemistry to investigate the relationship between IDO expression and tumor-infiltrating lymphocytes in endometrial cancer. more
GLB1
galactosidase beta 1
total:7
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. 2010 to the paper
Invitrogene anti-beta-Galactosidase antibody was used in immunocytochemistry for immunofluorescent staining to investigate the role of the NMDA receptors in the regulation of nicotine-conditioned place preference in dopamine neurons. more
glucuronyl C5 epimerase
glucuronic acid epimerase
total:1
Decreased expression of human D-glucuronyl C5-epimerase in breast cancer. 2008 to the paper
GenScript Corporation anti-GLCE antibody was used to perform western blot in order to study the GLCE expression in human breast cancer.
GPC3
glypican 3
total:1
Differential expression of syndecans and glypicans in chronically inflamed synovium. 2008 to the paper
Santa Cruz Biotechnologies anti-glypican-3 antibody was used in immunohistochemistry to investigate which HSPGs are expressed in knee joint synovia from patients with different forms of arthritis and normal individuals.
heparanase
total:6
Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. 2009 to the paper
Abgent anti-HPSE rabbit antibody (1:200) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules. more
HPSE2
heparanase 2 (inactive)
total:1
Heparanase expression in circulating lymphocytes of breast cancer patients depends on the presence of the primary tumor and/or systemic metastasis. 2007 to the paper
Santa Cruz Biotechnology HPA2 antibody was used in immunocytochemistry (1:100) to demonstrate that heparanase was expressed in lymphocytes of breast cancer PBMC.
HS3ST1
heparan sulfate-glucosamine 3-sulfotransferase 1
HS3ST2
heparan sulfate-glucosamine 3-sulfotransferase 2
HS3ST3A1
heparan sulfate-glucosamine 3-sulfotransferase 3A1
HS3ST3B1
heparan sulfate-glucosamine 3-sulfotransferase 3B1
HS3ST4
heparan sulfate-glucosamine 3-sulfotransferase 4
HS3ST5
heparan sulfate-glucosamine 3-sulfotransferase 5
HS3ST6
heparan sulfate-glucosamine 3-sulfotransferase 6
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
NG2
chondroitin sulfate proteoglycan 4
total:12
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
Chemicon anti-NG2 antibody (1:1500) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation. more
perlecan
heparan sulfate proteoglycan 2
total:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 to the paper
Chemicon monoclonal anti-perlecan antibody (MAB 1948) was used in frozen sections from mouse and in immunohistochemistry to study the identification of WARP as a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. more
SDC2
syndecan 2
total:2
Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells. 2005 to the paper
Seikagaku HSPG neo-epitope (exposed after heparitinase III digestion, clone 3G10) antibody was used in western blot to study thrombin-induced human vascular smooth muscle cell migration and proliferation more
SDC3
syndecan 3
total:1
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue. 2006 to the paper
Zymed Laboratories rabbit anti syndecan-3 antibody was used in immunohistochemistry to study its expression in human uterine tissue during prolonged labour
SDC4
syndecan 4
total:3
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans. 2008 to the paper
Santa Cruz Biotechnology anti-syndecan-4 antibody was used in immunocytochemistry to study the effect of heparanase on cell adhesion and spreading. more
syndecan
syndecan 1
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more
VCAN
versican
total:4
Expression of ZIC family genes in meningiomas and other brain tumors. 2010 to the paper
Sigma-Aldrich anti-chondroitin sulfate proteoglycan antibody was used to perform immunohistochemistry in order to investigate the expression profiles of ZIC genes in brain tumors. more