HSF1-dependent transactivation
gene
reagent
sample publication
sample review
total:4
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. 2011 to the paper
Cell Signaling Technology anti-phospho-PRAS40 was used to perform western blot in order to show that how growth factor signaling is inhibited by mTOR through mTOR-regulated phosphoproteome. more
total:13
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 to the paper
Affinity Bioreagents anti-phospho-CaMKII antibody was used for western blot in order to investigate the role of CaMKII in the regulation of pressure overload-induced cardiac hypertrophy to heart failure in mice. more
total:10
Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2. 2010 to the paper
Santa Cruz anti-phos-CaMKII antibody was used to perform western blot in order to study the role of cGMP-dependent protein kinase and RGS2 in local antihypertrophic effects of cardiac atrial natriuretic peptide. more
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
total:11
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import. 2007 to the paper
Assay Designs anti-FKBP52 antibody was used in western blot in order to investigate the functions of Hsp40-related J-domain proteins DJA1, DJA2, and DJA4 during mitochondrial import. more
total:25
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
Stressgen monoclonal anti-Hsc70 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
total:6
Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding. 2006 to the paper
Stressgen monoclonal anti-HSF1 antibody was used in human HeLa cells and in western blot, EMSA to study the role for the effects of MK2 on the regulation of HSF1 in inhibiting transcriptional activity and promotes HSP90 binding. more
total:10
Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. 2009 to the paper
Biosciences Hsp40 rabbit polyclonal antibody was used for western blot in order to investigate the role of SRPK1 in the regulation of SR protein phosphorylation. more
total:68
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-HSP90 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:8
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. 2010 to the paper
Millipore anti-H3S28P antibody was used in western blot in order to investigate the mechanism of how the embryonic stem cells chromatin structure change was regulated by condensin complexes during mitotic progression. more
total:1
Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice. 2010 to the paper
Santa Cruz Biotechnology Inc anti-GRP78 antibody was used for western blot in order to investigate the role of C/EBPB in the regulation of ER stress and pancreatic beta cell failure.
total:33
A gene signature-based approach identifies mTOR as a regulator of p73. 2008 to the paper
Santa Cruz polyclonal anti-mTOR (N-19 (alpha-FRAP) was used to perform western blot in order to show that mTOR is identified as a regulator of p73 by a gene signature-based approach. more
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:5
High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance. 2010 to the paper
Thermo Fisher anti-p23 antibody was used for performing immunoblotting and immunohistochemistry in order to study the effect of high levels of Hsp90 cochaperone p23 on tumor progression and prognosis in breast cancer. more
total:8
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Cell Signaling anti-raptor was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation. more