HS-GAG degradation
gene
reagent
sample publication
sample review
alpha L iduronidase
alpha-L-iduronidase
total:1
Intrathecal administration of AAV vectors for the treatment of lysosomal storage in the brains of MPS I mice. 2006 to the paper
BioMarin Pharmaceutical rabbit polyclonal IDUA antibody was used in immunohistochemistry (1:3000) to determine the expression level of IDUA in the brain after AAV vectors.
GLB1
galactosidase beta 1
total:7
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. 2010 to the paper
Invitrogene anti-beta-Galactosidase antibody was used in immunocytochemistry for immunofluorescent staining to investigate the role of the NMDA receptors in the regulation of nicotine-conditioned place preference in dopamine neurons. more
GPC3
glypican 3
total:1
Differential expression of syndecans and glypicans in chronically inflamed synovium. 2008 to the paper
Santa Cruz Biotechnologies anti-glypican-3 antibody was used in immunohistochemistry to investigate which HSPGs are expressed in knee joint synovia from patients with different forms of arthritis and normal individuals.
heparanase
total:6
Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. 2009 to the paper
Abgent anti-HPSE rabbit antibody (1:200) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules. more
HPSE2
heparanase 2 (inactive)
total:1
Heparanase expression in circulating lymphocytes of breast cancer patients depends on the presence of the primary tumor and/or systemic metastasis. 2007 to the paper
Santa Cruz Biotechnology HPA2 antibody was used in immunocytochemistry (1:100) to demonstrate that heparanase was expressed in lymphocytes of breast cancer PBMC.
perlecan
heparan sulfate proteoglycan 2
total:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 to the paper
Chemicon monoclonal anti-perlecan antibody (MAB 1948) was used in frozen sections from mouse and in immunohistochemistry to study the identification of WARP as a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. more
SDC2
syndecan 2
total:2
Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells. 2005 to the paper
Seikagaku HSPG neo-epitope (exposed after heparitinase III digestion, clone 3G10) antibody was used in western blot to study thrombin-induced human vascular smooth muscle cell migration and proliferation more
SDC3
syndecan 3
total:1
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue. 2006 to the paper
Zymed Laboratories rabbit anti syndecan-3 antibody was used in immunohistochemistry to study its expression in human uterine tissue during prolonged labour
SDC4
syndecan 4
total:3
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans. 2008 to the paper
Santa Cruz Biotechnology anti-syndecan-4 antibody was used in immunocytochemistry to study the effect of heparanase on cell adhesion and spreading. more
syndecan
syndecan 1
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more