HIV Infection
gene
reagent
sample publication
sample review
alpha-adaptin
adaptor related protein complex 2 subunit alpha 1
total:17
FCHo proteins are nucleators of clathrin-mediated endocytosis. 2010 to the paper
Transduction Laboratories mouse monoclonal anti-AP2A1 antibody was used to carry out western blot analysis in order to investigate the roles for FCHo1 and FCHo2 proteins in clathrin-mediated endocytosis in cell plasma membrane. more
AP1B1
adaptor related protein complex 1 subunit beta 1
total:3
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1g antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
AP1M1
adaptor related protein complex 1 subunit mu 1
AP1M2
adaptor related protein complex 1 subunit mu 2
AP1S1
adaptor related protein complex 1 subunit sigma 1
AP1S2
adaptor related protein complex 1 subunit sigma 2
AP1S3
adaptor related protein complex 1 subunit sigma 3
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
V. Faundez anti-sigma3-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
AP2A2
adaptor related protein complex 2 subunit alpha 2
total:5
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
Sigma anti-alpha-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. more
AP2B1
adaptor related protein complex 2 subunit beta 1
total:5
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1/2b antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
AP2M1
adaptor related protein complex 2 subunit mu 1
total:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 to the paper
BD Biosciences monoclonal anti-AP50 antibody was used in human HeLa cells or HUVECs and in western blot to study the role for clathrin adaptor AP2 in regulating thrombin receptor constitutive internalization and endothelial cell resensitization. more
APOBEC3G
apolipoprotein B mRNA editing enzyme catalytic subunit 3G
total:2
Mutations in C2orf37, encoding a nucleolar protein, cause hypogonadism, alopecia, diabetes mellitus, mental retardation, and extrapyramidal syndrome. 2008 to the paper
Abgent rabbit polyclonal anti-C2orf37 antibody was used to perform immunohistochemistry in order to study the C2orf37 Mutations mediated Woodhouse-Sakati syndrome. more
ARF1
ADP ribosylation factor 1
total:8
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 to the paper
Affinity Bioreagents anti-Arf antibody was used to perform western blot in order to study the interaction between Arf and Poliovirus Protein 3CD and its effect on poliovirus replication. more
ATP6V1H
ATPase H+ transporting V1 subunit H
total:1
Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney. 2007 to the paper
Santa Cruz Biotechnology anti-human vacuolar type H+-ATPase B1/2 (V-ATPase) antibody was used in immunohistochemistry to localize broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney
B2M
beta-2-microglobulin
total:5
Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression. 2008 to the paper
Dako anti-B2m was used to perform immunohistochemistry in order to study the presence of specific populations of tumor infiltrating lymphocytes in diagnostic primary melanoma biopsies are associated with outcome in clinically stage II melanoma patients. more
BANF1
BAF nuclear assembly factor 1
total:1
Binding of barrier to autointegration factor (BAF) to histone H3 and selected linker histones including H1.1. 2005 to the paper
Dr Roc o Montes de Oca anti-BAF antibody was used in immynoprecipitation to study the role of binding of barrier to autointegration factor (BAF) and selected linker histones.
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
total:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Zymed Laboratories mouse anti-beta TRCP antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
CCNH
cyclin H
total:3
Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. 2005 to the paper
Santa Cruz Biotechnology cyclin H antibody was used in western blot to study the role of Dmp1 in Ras-Raf-Arf signaling. more
CCNT1
cyclin T1
total:5
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. 2008 to the paper
Santa Cruz anti-cyclin T1 antibody was used to perform western blot in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters. more
CCR5
C-C motif chemokine receptor 5 (gene/pseudogene)
total:28
Effects of ferumoxides-protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells. 2008 to the paper
Biolegend FITC conjugated mouse anti-human CD195 IgG2a was used in flow cytometry in order to demonstrate that endocytosed FePro nanoparticles did not significantly affect immunological properties of THP-1 cells more
CD247
CD247 molecule
total:68
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD3 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
CD28
CD28 molecule
total:25
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD28 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
CD4
CD4 molecule
total:118
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Beckman coulter anti-CD4 PC5 was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
CD8B
CD8b molecule
total:5
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Becton Dickinson anti-CD8b antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
cdk7
cyclin dependent kinase 7
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK7 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
cdk9
cyclin dependent kinase 9
total:11
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK9 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
CHMP2B
charged multivesicular body protein 2B
total:1
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. 2011 to the paper
Abcam antibody mouse rabbit anti-CHMP2B antibody was used to perform immunohistochemistry in order to study quantification of CHMP2B on intercellular bridges at different stages.
CHMP3
charged multivesicular body protein 3
total:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 to the paper
Bethyl Laboratory Inc. rabbit anti-Vps24 antibody was used in western blot to study the interaction of the mammalian endosomal sorting complex required for rransport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1
CHMP4A
charged multivesicular body protein 4A
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-CHMP4A was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
CHMP4B
charged multivesicular body protein 4B
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-CHMP4B was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
CXCR4
C-X-C motif chemokine receptor 4
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
CypA
peptidylprolyl isomerase A
total:9
Hepatitis B virus (HBV) surface antigen interacts with and promotes cyclophilin a secretion: possible link to pathogenesis of HBV infection. 2010 to the paper
Proteintech anti-CypA monoclonal antibody was used to perform western blot in order to study the role of HBV small surface protein(SHBs) in promoting the pathogenesis of HBV infection. more
DNA ligase IV
DNA ligase 4
total:4
The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo. 2009 to the paper
Abcam DNA ligase IV antibody was used for western blot in order to investigate the role of the c-terminal domain of cernunnos/XLF in the regulation of DNA repair in vivo. more
ELL
elongation factor for RNA polymerase II
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit
total:3
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-XPD was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit
total:5
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-XPB was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
FCP1
CTD phosphatase subunit 1
total:4
The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. 2013 to the paper
Abcam RNA polymerase II CTD repeat YSPTSPS peptide-phospho S2 antibody was used to perform western blot in order to study the structure and function of the tripartite complex containing P-TEFb,AFF4HIV and HIV Tat. more
Fyn
FYN proto-oncogene, Src family tyrosine kinase
total:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-FYN antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking. more
gamma-adaptin
adaptor related protein complex 1 subunit gamma 1
total:15
Adaptor heat shock protein complex formation regulates trafficking of the asialoglycoprotein receptor. 2006 to the paper
Sigma mouse monoclonal anti-gamma-subunit of AP1 antibody was used in western blot to study the effect of adaptor heat shock protein complex formation on trafficking of the asialoglycoprotein receptor in HuH-7 and Trf1 human hepatoma cell lines. more
GTF2A1
general transcription factor IIA subunit 1
GTF2A2
general transcription factor IIA subunit 2
total:1
Human La is found at RNA polymerase III-transcribed genes in vivo. 2005 to the paper
Santa Cruz Biotechnology TFIIA antibody was used in ChIP assay to study the association of human autoantigen La with pol III-transcribed genes in vivo
GTF2E1
general transcription factor IIE subunit 1
total:2
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 to the paper
Santa Cruz TFIIEa antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires. more
GTF2E2
general transcription factor IIE subunit 2
GTF2F1
general transcription factor IIF subunit 1
total:3
Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin. 2009 to the paper
Santa Cruz anti-TFIIF antibody was used to perform ChIP assays in order to study the association between the papillomavirus E2 proteins, the host Brd4 protein and the transcriptionally active cellular genes. more
GTF2F2
general transcription factor IIF subunit 2
GTF2H3
general transcription factor IIH subunit 3
total:1
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. 2009 to the paper
Santa Cruz Biotechnology TFIIH antibody was used in western blot to study the regulation of aromatase transcription and estrogen biosynthesis in adipose stromal cells (ASCs).
HCK
HCK proto-oncogene, Src family tyrosine kinase
total:9
Regulation of p73 by Hck through kinase-dependent and independent mechanisms. 2007 to the paper
Santa Cruz rabbit polyclonal anti-Hck was used to perform western blot and immunoprecipitation and immunocytochemistry in order to show the mechanisms through which Hck regulates p73 function more
HLA-A
major histocompatibility complex, class I, A
total:8
Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. 2008 to the paper
Santa Cruz Biotechnology anti-HLA-A(A-18) antibody was used to perform immunohistochemistry in order to study tumor and tumor-stromal cell interactions. more
HMGA1
high mobility group AT-hook 1
total:3
HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells. 2009 to the paper
Santa Cruz anti-HMGA1 antibody was used to perform western blot in order to study the role of HMGA2 in maintaining the oncogenic RAS-induced epithelial-mesenchymal transition. more
KPNA1
karyopherin subunit alpha 1
total:1
Novel nuclear import of Vpr promoted by importin alpha is crucial for human immunodeficiency virus type 1 replication in macrophages. 2007 to the paper
MBL monoclonal importin alpha 5/7 antibody was used in western blot to study novel nuclear import of Vpr promoted and its roles in human immunodeficiency virus type 1 replication in macrophages
KPNB1
karyopherin subunit beta 1
total:7
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-importin beta antibody (sc-137016) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
Ku70
X-ray repair cross complementing 6
total:19
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Abcam anti-Ku70 antibody was used to perform immunoblotting in order to studythe role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
Ku80
X-ray repair cross complementing 5
total:22
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Life Technologies anti-Ku80 antibody was used to perform immunoprecipitation and immunofluorescence in order to study IRF-3-dependent innate immunity. more
Lck
LCK proto-oncogene, Src family tyrosine kinase
total:18
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology Lck antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
MNAT1
MNAT1 component of CDK activating kinase
total:2
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". 2006 to the paper
Santa Cruz monoclonal anti-Mat1 antibody (F-6) was used in human T98G cells and in western blot to study the role for cyclins and CDK "inhibitors" in Thr172 phosphorylation of CDK4. more
NCBP1
nuclear cap binding protein subunit 1
total:2
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Protein-Tech anti-CBP80 antibody was used in western blot in order to investigate the function of surveillance complex associated with ribosome during nonsense-mediated mRNA decay (NMD). more
NCBP2
nuclear cap binding protein subunit 2
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abgent CBP20 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
NELFA
negative elongation factor complex member A
NELFCD
negative elongation factor complex member C/D
NELFE
negative elongation factor complex member E
NMT1
N-myristoyltransferase 1
total:1
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 to the paper
BD Transduction Laboratories anti-NMT1 antibody was used in western blot to detect NMT1 in SK-OV-3 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.
NMT2
N-myristoyltransferase 2
total:1
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 to the paper
BD Transduction Laboratories anti-NMT2 antibody was used in western blot to detect NMT2 in SK-OV-3 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.
NPM1
nucleophosmin 1
total:11
Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. 2010 to the paper
Zymed anti-NPM antibody was used for western blot in order to investigate the role for activated Bax in the regulation of p53-dependent, transcription-independent neural precursor cell apoptosis. more
nucleoporin p62
nucleoporin 62
total:8
Fractionation of the Coxiella burnetii parasitophorous vacuole. 2008 to the paper
BD Biosciences mouse anti-human nuclear pore protein nucleoporin p62 antibody was used to perform western blot in order to develope a method to separate intact parasitophorous vacuole from host cell material. more
NUP133
nucleoporin 133
total:1
The nucleoporin Nup153 has separable roles in both early mitotic progression and the resolution of mitosis. 2009 to the paper
Covance anti-nucleoporin antibody was used to perform western blot in order to study the roles of Nup153 plays in mitosis.
NUP153
nucleoporin 153
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Abcam monoclonal anti-NUP was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
NUP88
nucleoporin 88
total:1
Caspases target only two architectural components within the core structure of the nuclear pore complex. 2006 to the paper
BD Biosciences monoclonal Nup88 antibody was used in western blot to identify caspase targets in the core structure of nuclear pore complex in Hela cells
PA200
proteasome activator subunit 4
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal regulator PA200 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
PACS1
phosphofurin acidic cluster sorting protein 1
Pak2
p21 (RAC1) activated kinase 2
total:6
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 to the paper
Santa Cruz Biotechnology anti-PAK-2 antibody was used for western blot in order to investigate the role of PAK-2 in the regulation of anticancer drug-induced cell apoptosis. more
PDCD6IP
programmed cell death 6 interacting protein
total:2
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. 2010 to the paper
Cell Signaling ALIX antibody was used to perform western blot in order to indicate an important role for the ubiquitin ligase activity of HOIP in CD40 signaling. more
POLR2B
RNA polymerase II subunit B
total:1
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 to the paper
Santa Cruz anti-the large subunit of RNA polymerases II antibody (N20) was used in western blot to study the role for the STAGA subunit ADA2b in regulating human GCN5 catalysis.
POM121
POM121 transmembrane nucleoporin
PSIP1
PC4 and SFRS1 interacting protein 1
total:8
Integration of HIV-1 DNA is regulated by interplay between viral rev and cellular LEDGF/p75 proteins. 2010 to the paper
R&D Systems anti-LEDGF/ p75 antibody was used to perform immunoprecipitation, immunocytochemistry, and western blot in order to study the regulation of HIV-1 DNA integration by viral Rev and cellular LEDGF/p75s interplay. more
PSMA1
proteasome 20S subunit alpha 1
total:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 to the paper
Abcam C2 proteasome antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway more
PSMA3
proteasome 20S subunit alpha 3
total:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Santa Cruz Biotechnology anti-Psc3 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
PSMA4
proteasome 20S subunit alpha 4
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International mouse monoclonal anti-human 20S proteasome subunit alpha4 was used for immunohistochemistry to investigate the effect of immunoproteasome on the Multiple Sclerosis pathogenesis. more
PSMA7
proteasome 20S subunit alpha 7
total:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Enzo Life Sciences anti-alpha7 antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
PSMB1
proteasome 20S subunit beta 1
total:2
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta1 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD). more
PSMB5
proteasome 20S subunit beta 5
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
PSMB8
proteasome 20S subunit beta 8
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP7 antibody was used for immunohistochemistry to study the effect of immunoproteasome on the Multiple Sclerosis. more
PSMB9
proteasome 20S subunit beta 9
total:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP2 antibody was used to perform immunohistochemistry to study the role of immunoproteasome in the Multiple Sclerosis pathogenesis. more
PSMC4
proteasome 26S subunit, ATPase 4
total:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 to the paper
Cell Signaling Technology anti-phospho-Ser235/236-S6 antibody was used to perform immunocytochemistry in order to study the capacity of rapamycin to provide neuroprotection in Parkinson disease models. more
PSMC6
proteasome 26S subunit, ATPase 6
total:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 to the paper
New England BioLabs antiphospho-p44/42 MAPK antibody and p44/42 MAPK antibody (PhosphoPlus p44/42 MAPK antibody kit) was used in western blot to study the physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing RhoGEFs.
PSMD2
proteasome 26S subunit, non-ATPase 2
total:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S2 subunit antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication.
PSMD4
proteasome 26S subunit, non-ATPase 4
total:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S5a antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication. more
PSMD9
proteasome 26S subunit, non-ATPase 9
total:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p27 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
PSME1
proteasome activator subunit 1
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International rabbit polyclonal anti-PA28alpha antibody was used for immunohistochemistry to determine the role of immunoproteasome in the Multiple Sclerosis. more
PSME2
proteasome activator subunit 2
total:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 to the paper
BIOMOL anti-proteasome activator 28 subunit beta (PA28beta) antibodoy was used to perform western blot in order to confirm the effect on the expression of proteasome-interacting proteins caused by chronic ethanol feeding.
Rac1
Rac family small GTPase 1
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
RAE1
ribonucleic acid export 1
total:1
The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response. 2008 to the paper
R&D Systems anti-RAE-1 antibody was used in flow cytometry in order to study the role of immune responses in the tumorigenicity of embryonic stem cells
Ran
RAN, member RAS oncogene family
total:17
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-RAN antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
RANBP2
RAN binding protein 2
total:4
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
Santa Cruz polyclonal anti-RanBP2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
RBX1
ring-box 1
total:5
Poxvirus ankyrin repeat proteins are a unique class of F-box proteins that associate with cellular SCF1 ubiquitin ligase complexes. 2008 to the paper
Lab Vision rabbit-anti-RBX1 antibody was used in western blot in order to identify the poxviral motif as a functional F-box more
RCC1
regulator of chromosome condensation 1
total:3
A survivin-ran complex regulates spindle formation in tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-human RCC1 antibody was used to perform western blot in order to study the role of survivin-Ran signaling in spindle formation in tumor cells. more
RNA polymerase II
RNA polymerase II subunit A
total:69
RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. 2011 to the paper
Santa Cruz anti-Rpb1 was used to perform western blot and ChIP assay in order to show that histone mRNA 3 end processing needs the phosphorylation of RNAP II CTD Thr4. more
RPS27A
ribosomal protein S27a
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
Skp1
S-phase kinase associated protein 1
total:8
APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. 2009 to the paper
Zymed mouse monoclonal anti-Skp1 antibody was used in western blot to investigate the regulation of Cdc20 stability during SAC activation in mammalian cells and explore the contribution of spindle checkpoint proteins to Cdc20 stability. more
SLC25A4
solute carrier family 25 member 4
total:3
Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-ANT antibody was used for western blot in order to investigate the role of Ischaemic preconditioning in the regulation of proteasomal activity and the degradation of PKCdelta during reperfusion. more
SLC25A5
solute carrier family 25 member 5
total:1
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. 2007 to the paper
Dr. Douglas C. Wallace (University of California, Irvine) ANT2-specific antiserum was used in western blot to study the regulation of insulin secretion by SIRT4
SSRP1
structure specific recognition protein 1
total:2
FACT facilitates chromatin transcription by RNA polymerases I and III. 2009 to the paper
Abcam anti-SSRP1 was used to perform immunoprecipitation in order to to determine whether indeed FACT associates with Pol I complexes. more
SUPT4H1
SPT4 homolog, DSIF elongation factor subunit
SUPT5H
SPT5 homolog, DSIF elongation factor subunit
total:2
Transcription termination factor Pcf11 limits the processivity of Pol II on an HIV provirus to repress gene expression. 2007 to the paper
Santa Cruz Biotechnology anti-Spt5 (sc-28678) antibody was used in western blot to study the role of transcription termination factor Pcf11 on the processivity of Pol II more
TAF1
TATA-box binding protein associated factor 1
total:7
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-TAF1 antibody was used to perform Chip in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
TAF10
TATA-box binding protein associated factor 10
total:2
SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation. 2009 to the paper
Upstate Biochemistry amti-RNA polymerase II antibody was used for immunoprecipitation in order to indicate that SUMOylation is mediated through reduced CDK7-induced phosphorylation of SF-1. more
TAF11
TATA-box binding protein associated factor 11
total:2
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-TAF11 antibody was used to perform Chip or Web in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
TAF12
TATA-box binding protein associated factor 12
total:2
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 to the paper
Irwin Davidson TAF12 antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires. more
TAF13
TATA-box binding protein associated factor 13
TAF4
TATA-box binding protein associated factor 4
total:1
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 to the paper
Irwin Davidson TAF4 antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires.
TAF5
TATA-box binding protein associated factor 5
total:1
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Sigma-Aldrich anti-TAF5 antibody was used to perform Chip in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters.
TAF6
TATA-box binding protein associated factor 6
TAF9
TATA-box binding protein associated factor 9
total:1
Core promoter binding by histone-like TAF complexes. 2005 to the paper
Santa Cruz Biotechnology anti-TAF9 antibody was used in western blot, immunoprecipitation, and EMSA to study histone-like TAF complexes
TAFII105
TATA-box binding protein associated factor 4b
TBP
TATA-box binding protein
total:14
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-TBP antibody was used to perform Chip or Web in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
ELOB
elongin B
total:4
Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome. 2008 to the paper
Santa Cruz anti-Elongin B antibody was used in immunoprecipitation in order to demonstrate that SAP130 may link CRL mediated ubiquitination to gene expression. more
TFIIB
general transcription factor IIB
total:8
Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin. 2009 to the paper
Santa Cruz anti-TFIIB antibody was used to perform ChIP assays in order to study the association between the papillomavirus E2 proteins, the host Brd4 protein and the transcriptionally active cellular genes. more
TPR
translocated promoter region, nuclear basket protein
TSG101
tumor susceptibility 101
total:15
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Abcam monoclonal anti-Tsg101 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
UBC
ubiquitin C
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
ubiquitin
ubiquitin B
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
VPS4A
vacuolar protein sorting 4 homolog A
total:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 to the paper
Bethyl Laboratory Inc. rabbit anti-SKD1 antibody was used in western blot to study the interaction of the mammalian endosomal sorting complex required for rransport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1
XPO1
exportin 1
total:7
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. 2009 to the paper
Santa Cruz Biotechnology CRM-1 antibody was used for Western blotting in order to investigate the effect of LKB1 on nucleocytoplasmic transport. more
XRCC4
X-ray repair cross complementing 4
total:3
Adeno-associated virus replication induces a DNA damage response coordinated by DNA-dependent protein kinase. 2009 to the paper
Serotech anti-XRCC4 antibody was used to carry out western blot analysis in order to investigate the effect of adeno-associated virus and adenovirus coinfection on inducing cellular DNA damage response. more