G alpha (s) signalling events
gene
reagent
sample publication
sample review
total:8
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Abcam ACTH antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:2
Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. 2005 to the paper
FabGennix isoform-specific anti-adenylate cyclase antibody was used in western blot to study the effedt of interferon-gamma on adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia. more
total:2
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. 2007 to the paper
Santa Cruz Biotechnology AC2 antibody was used in western blot to demonstrate stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. more
total:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Santa Cruz anti-adenylyl cyclase III antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
total:3
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 to the paper
Santa Cruz Biotechnology anti-adenylate cyclase antibody was used in western blot to study the role of PDE3B and its interaction with PKB for regulation of specific cAMP pools and signalling pathways by insulin. more
total:4
Accelerated variant of idiopathic pulmonary fibrosis: clinical behavior and gene expression pattern. 2007 to the paper
Chemicon Int rabbit anti-human adenosine 2B receptor (A2BAR) polyclonal antibody was used to perform immunohistochemistry(5 ug/ml) and western blot(2 ug/ml) in order to study the clinical and molecular features of accelerated IPF. more
total:3
Circadian-related heteromerization of adrenergic and dopamine D? receptors modulates melatonin synthesis and release in the pineal gland. 2012 to the paper
Santa Cruz Biotechnology rabbit anti-alpha1 receptor antibody was used to perform immunoprecipitation and immunostaining to study the modulation of the synthesis and release of the melatonin in the pineal gland by the heteromerization of adrenergic and dopamine D₄ receptors. more
total:7
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
Santa Cruz Biotechnology anti-ADRB2 C-tail antibody was used to carry out western blot analysis in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:5
Mechanisms responsible for vascular hyporesponsiveness to adrenomedullin after hemorrhage: the central role of adrenomedullin binding protein-1. 2005 to the paper
Accurate Chemical AMBP-1 antibody was used in western blot to study the role of adrenomedullin binding protein-1 in vascular hyporesponsiveness to adrenomedullin after hemorrhage. more
total:1
Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration. 2007 to the paper
Santa Cruz Biotechnology type I ADH antibody was used in western blot to study the role of alcohol and aldehyde dehydrogenase activities in rat liver regeneration.
total:1
Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats. 2008 to the paper
Cell Signaling Technology phospho-Erk1 and Erk2 (phospho-p42/p44 MAPK) antibody was used in western blot in order to demonstrate that continuous GH induces CYP2C12 expression by activating Erk1 and Erk2 via the GHR
total:6
Role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma: report of six cases and review of the literature. 2007 to the paper
Dako calcitonin antibody (1:200) was used in immunohistochemistry to study the role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma. more
total:6
Role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma: report of six cases and review of the literature. 2007 to the paper
Dako calcitonin antibody (1:200) was used in immunohistochemistry to study the role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma. more
total:4
Corticotropin-releasing hormone, its binding protein and receptors in human cervical tissue at preterm and term labor in comparison to non-pregnant state. 2006 to the paper
Santa Cruz Biotechnology rabbit polyclonal antibody against CRH was used in immunohistochemistry to detect the localization of CRH in human cervix. more
total:6
Regulation of corticotropin-releasing hormone receptor-2 expression in human cord blood-derived cultured mast cells. 2005 to the paper
Santa Cruz Biotechnology polyclonal goat anti-human/mouse/rat CRH-R1 antibody (V-14 sc-12381) was used in immunocytochemistry to study the expression of CRH-R1 and CRH-R2 n human cord blood-derived cultured mast cells. more
total:3
Evidence for the presence of the type 2 corticotropin releasing factor receptor in the rodent cerebellum. 2006 to the paper
Santa Cruz Biotechnology CRF-RII antibody was used in western blot and immunohistochemistry to demonstrate that the CRF family of peptides modulates cerebellar output by binding to multiple CRF receptors. more
total:9
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. 2008 to the paper
Abcam murine monoclonal anti-PTGER4 antibody was used to perform flow cytometric analysis in order to study the important role of CD30 signaling in Hodgkin's and anaplastic large cell lymphoma (ALCL) cell lines. more
total:2
Changes in serum inhibin B during normal male puberty. 2005 to the paper
Autodelfia anti-FSH antibody was used in immunocytochemistry to study the changes in serum inhibin B during normal male puberty. more
total:1
Knocking down gene expression for growth hormone-releasing hormone inhibits proliferation of human cancer cell lines. 2008 to the paper
Santa Cruz Biotechnology anti-GHRH antibody was used to perform western blot in order to study inhibition of the GHRH gene expression affects proliferation of human cancer cell lines.
total:1
Synergistic inhibition of growth of lung carcinomas by antagonists of growth hormone-releasing hormone in combination with docetaxel. 2006 to the paper
Dr.Andrew V. Schally (Veterans Affairs Medical Center) pGHRH-R antibody (1:2,000) was used in western blot to study the effect of antagonists of growth hormone-releasing hormone (GHRH) MZ-J-7-138 and JV-1-92 on H460 human non-small cell lung carcinoma (NSCLC) xenografted orthotopically into nude mice.
total:2
Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r). 2007 to the paper
Abcam GLP-1R antibody was used in western blot to study protein expression of GLP-1R to reveal tissue-specific strain differences in pancreas (congenic>B6) and stomach (B6>congenic). more
total:13
Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. 2009 to the paper
Sigma anti-glucagon antibody was used to perform immunohistochemistry in order to study the role of mitochondrial flavoprotein apoptosis inducing factor. more
total:4
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
United States Biological rabbit anti-GNAS antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 to the paper
Dr. W. Simonds (NINDK) rabbit anti-VAChT antibody was used in western blot to study the localization and differential interaction of R7 RGS proteins with R7BP and R9AP in neurons of vertebrate retina.
total:4
Metastatic embryonal carcinoma in the maxillary gingiva. 2008 to the paper
DAKO anti-HCG antibody was used to perform immunohistochemistry in order to study the metastases of embryonal carcinoma in the maxillary gingiva. more
total:1
Serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients. 2006 to the paper
Santa Cruz Biotechnology goat anti-human serotonin 6 receptor antibody (Santa Cruz sc-26668) was used in tissue sections from human brain and in immunohistochemistry to study the expression of serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients.
total:3
A crucial role of MafA as a novel therapeutic target for diabetes. 2005 to the paper
Dako guinea pig polyclonal anti-insulin antibody was used in immunohistochemistry to study the role of MafA for therapy of diabetes. more
total:1
Cytochrome b5 expression in gonadectomy-induced adrenocortical neoplasms of the domestic ferret (Mustela putorius furo). 2008 to the paper
ATCC mouse anti-human LHR antibody was used in immunohistochemistry at 1:100 dilution in order to demonstrate that that cyt b5 is upregulated during gonadectomy-induced adrenocortical neoplasia and is a marker of androgen synthetic potential in these tumors
total:1
Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk. 2005 to the paper
Santa Cruz Biotechnology MC1R antibody (N-19) antibody was used in western blot and immunohistochemistry to study its expression in skin cancer abd red hair persons
total:1
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. 2006 to the paper
Abcam PDE10A mouse monoclonal antibody was used in western blot andimmunohistochemistry to study Cellular and subcellular localization of PDE10A.
total:1
Expression of PDE11A in normal and malignant human tissues. 2005 to the paper
FabGennix anti-Cyclic nucleotide phosphodiesterase 11A antibody was used in immunohistochemistry and western blot to study the expression of PDE11A in normal and malignant human tissues.
total:2
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. 2006 to the paper
Chemicon PDE1B1 antibody was used in western blot to study Cellular and subcellular localization of PDE10A. more
total:1
Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells. 2005 to the paper
Santa Cruz Biotech anti-PDE3B antibody was used in western blot to study the suppression of cyclic GMP-specific phosphodiesterase 5 promoting apoptosis and inhibiting growth in HT29 cells.
total:3
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Abcam anti-PDE4 antibody was used in western blot in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
total:1
Short-term or long-term treatments with a phosphodiesterase-4 (PDE4) inhibitor result in opposing agonist-induced Ca(2+) responses in endothelial cells. 2008 to the paper
FabGennix anti-PDE4C antibody was used in western blot to study the effects of longer term pre-treatment with a specific inhibitor of phosphodiesterase-4 (PDE4), on [Ca2+]i, cAMP levels, and PDE activity and expression in HUVEC.
total:1
Expression of the cAMP-phosphodiesterase PDE4D isoforms and age-related changes in follicle-stimulating hormone-stimulated PDE4 activities in immature rat sertoli cells. 2007 to the paper
Santa Cruz Biotechnology anti-PDE4D antibody was used in western blot to evaluate the cAMP response to FSH and the FSH-stimulated PDE activities in proliferating.
total:4
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-EP2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:3
Effect of parathyroid-hormone-related protein on human platelet activation. 2007 to the paper
Santa Cruz Biotechnology affinity-purified mouse monoclonal anti-PTH1R antibody was used in western blot to determine the content of PTH1R in platelets from patients during AMI and patients in the absence of AMI, and Santa Cruz Biotechnology FITC conjugated anti-PTH1R antibody was used in flow cytometry to detect PTH1R expression on the platelet surface obtained from patients during AMI and patients with similar cardiovascular risk factors without AMI. more
total:1
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 to the paper
Abcam anti-H3 antibody was used for coimmunoprecipitation in order to illustrate the role of c-Myb in MLL-associated leukemogenesis.
total:2
Application of light microscopical and ultrastructural immunohistochemistry in the study of goblet cell carcinoid in the appendix. 2008 to the paper
BioGenex Laboratories rabbit anti-human secretin antibody was used in immunohistochemistry in order to develop a combined histochemical and immunohistochemical procedure to reveal the dual nature of goblet cell carcinoide more
total:1
Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results. 2007 to the paper
AbD Serotec rabbit anti-secretin receptor polyclonal antibody (1:1000) was used in western blot and immunohistochemistry to study secretin-receptor and secretin-receptor-variant expression in gastrinomas
total:1
Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation. 2005 to the paper
Novocastra Laboratories monoclonal anti-TSHr antibody (AA 211 414) was used in immunocytochemistry to study TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy
total:5
Bone marrow cells produce a novel TSHbeta splice variant that is upregulated in the thyroid following systemic virus infection. 2009 to the paper
Santa Cruz Biotechnology anti-TSHb antibody was used to carry out immunopreciptation assays in order to characterize the function of a novel TSH splice variant during immunological stress. more