G alpha (q) signalling events
gene
reagent
sample publication
sample review
total:1
Circadian-related heteromerization of adrenergic and dopamine D? receptors modulates melatonin synthesis and release in the pineal gland. 2012 to the paper
Abcam rabbit anti-alpha1 receptor antibody was used to perform immunoprecipitation and immunostaining to study the modulation of the synthesis and release of the melatonin in the pineal gland by the heteromerization of adrenergic and dopamine D₄ receptors.
total:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 to the paper
IgG corporation rabbit polyclonal anti-ang II serum was used in immunohistochemistry in order to study the glomerular AGT's expression and its correlation with expression of other RAS components more
total:9
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
Santa Cruz rabbit anti-AT1 was used to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
total:7
Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. 2010 to the paper
Invitrogen anti-ANXA1 andibody was used to perform immnunohistochemistry, western blot and ELISA in order to study the functions of Annexin A1 in the anti-inflammatory and neuroprotective role of microglia. more
total:81
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Chemicon anti-APP was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:1
Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT. 2005 to the paper
Proteintech Group rabbit anti-GEFT antibody was used to carry out immunohistochemistry assay and western blot analysis in order to characterize the roles for Rho-GEFs in modulating skeletal muscle regeneration, myogenesis, and adipogenesis.
total:1
Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration. 2007 to the paper
Santa Cruz Biotechnology type I ADH antibody was used in western blot to study the role of alcohol and aldehyde dehydrogenase activities in rat liver regeneration.
total:1
Prolactin activates mitogen-activated protein kinase signaling and corticotropin releasing hormone transcription in rat hypothalamic neurons. 2009 to the paper
Aachen VP (vasopressin) monoclonal antibody was used in immunohistochemistry in order to investigate the mechanism for the prolactin-mediated hypothalamic pituitary adrenal axis inhibition during lactation in hypothalamic neurons.
total:4
ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanism. 2007 to the paper
Novus anti-FIH was used in western blot to investigate the interaction between ASB4 and FIH in human HEK-293T cells. more
total:1
Novel regional and developmental NMDA receptor expression patterns uncovered in NR2C subunit-beta-galactosidase knock-in mice. 2007 to the paper
Chemicon International polyclonal cholecystokinin antibody was used in immunohistochemistry to study novel functions of NR2C-containing NMDA receptors.
total:3
M(1) and M(2) muscarinic acetylcholine receptor subtypes mediate Ca(2+) channel current inhibition in rat sympathetic stellate ganglion neurons. 2006 to the paper
Chemicon International rabbit anti-M1 antibody (1:200) was used in immunocytochemistry to study the role of M (1) and M (2) muscarinic acetylcholine receptor subtypes in mediating Ca (2+) channel current inhibition in rat sympathetic stellate ganglion neurons. more
total:1
Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C. 2005 to the paper
BD Biosciences mouse monoclonal antibody to DGK theta theta was used in western blot to provide evidence in vitro and in vivo for a major role for PKCepsilon and/or PKCeta activation in the regulation of DGKdelta translocation to the plasma membrane.
total:6
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
Santa Cruz goat anti-ETA was used in 1:50 dilution to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
total:10
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
IBL rabbit anti-ETB was used in 1:400 dilution to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
total:9
Expression of endothelial nitric oxide synthase and endothelin-1 in skin tissue from amputated limbs of patients with complex regional pain syndrome. 2008 to the paper
R&D systems rat anti-human ET-1 antibody (3G10) was used in immunohistochemistry to examine the distribution of eNOS and ET-1 in relation to vascular density represented by the endothelial marker CD31-immunoreactivity in skin tissue from amputated limbs of patients with CRPS. more
total:4
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-EP1 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:2
Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. 2005 to the paper
Upstate Biotechnologies Par-3 antibody was used in western blot and immunocytochemistry to study the role of Par-3 in epithelial cell polarization in mammals. more
total:1
The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells. 2009 to the paper
LifeSpan Biosciences anti-FPRL1 antibody (1:100) was used in flow cytometry in order to study the role of pro-inflammatory peptide LL-37 in the ovarian tumor progression
total:5
Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results. 2007 to the paper
Chemicon rabbit anti-gastrin polyclonal antibody (1:1000) was used in immunohistochemistry to study secretin-receptor and secretin-receptor-variant expression in gastrinomas more
total:4
Application of light microscopical and ultrastructural immunohistochemistry in the study of goblet cell carcinoid in the appendix. 2008 to the paper
BioGenex Laboratories rabbit anti-human bombesin antibody was used in immunohistochemistry in order to develop a combined histochemical and immunohistochemical procedure to reveal the dual nature of goblet cell carcinoide more
total:13
Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. 2009 to the paper
Sigma anti-glucagon antibody was used to perform immunohistochemistry in order to study the role of mitochondrial flavoprotein apoptosis inducing factor. more
total:11
Caveolin-1 alters Ca(2+) signal duration through specific interaction with the G alpha q family of G proteins. 2008 to the paper
Santa Cruz rabbit anti-Galphaq antibody was used in immunocytochemistry to study the effect of the interaction between caveolin-1 and the Galphaq family of G proteins on Ca2+ signal duration. more
total:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 to the paper
Dr. W. Simonds (NINDK) rabbit anti-VAChT antibody was used in western blot to study the localization and differential interaction of R7 RGS proteins with R7BP and R9AP in neurons of vertebrate retina.
total:5
Presence of immunoreactive gonadotropin releasing hormone (GnRH) and its receptor (GnRHR) in rat ovary during pregnancy. 2008 to the paper
Chemicon International mouse monoclonal anti-GnRH antibody (1:200) was used in immunohistochemistry to study its cellular localization in the rat ovary. more
total:9
Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2. 2008 to the paper
Santa Cruz Biotechnolog GRK2 polyclonal antibody was used to immunodetect myocardial levels in order to study the uncoupling of myocardial beta-Adrenergic receptor signaling during coronary artery bypass grafting: The Role of GRK2 more
total:3
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-GRK5 antibody was used to perform western blot in order to study the important role of GRK4 in D3 receptor's signaling in human proximal tubule cells. more
total:7
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 to the paper
BD Biosciences mGluR1 antibody was used in western blot to study the role of molecular alterations in the cerebellum of the PMCA2-null in Purkinje neurons. more
total:3
Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin. 2005 to the paper
Upstate Biotechnology rabbit polyclonal anti-mGluR5 antibody was used in western blot and immunoprecipitation to study metabotropic glutamate receptor signaling more
total:1
Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon. 2005 to the paper
Dr. Robert T. Jensen anti-GRP-R antibody was used in immunohistochemistry to study the role of neuromedin B and its receptor in both normal and malignant epithelial cells lining the colon.
total:4
Repeated amphetamine administration induces Fos in prefrontal cortical neurons that project to the lateral hypothalamus but not the nucleus accumbens or basolateral amygdala. 2008 to the paper
Santa Cruz Biotechnology anti-orexin A antibody (1:1000) was used in immunohistochemistry in order to to identify the mPFC subcortical pathway (s) activated by a sensitizing regimen of AMPH more
total:5
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 to the paper
Calbiochem IP3R1 antibody was used in western blot and immunohistochemistry to study the role of molecular alterations in the cerebellum of the PMCA2-null in Purkinje neurons. more
total:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 to the paper
Santa Cruz Biotechnology goat anti-IP3R2 antibody was used in western blot to study the binding of phospholipid scramblase 1 to the promoter region of the inositol 1, 4, 5-triphosphate receptor type 1 more
total:3
Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer. 2008 to the paper
Abcam anti-KiSS1 antibody was used in western blot to study the effect of the large isoform of MRJ (DNAJB6) on malignant activity of breast cancer. more
total:1
Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated. 2010 to the paper
DAKO anii-CKH antibody was used to carry out immunohistochemistry assays in order to investigate the regulation of Estrogen receptor beta activated apoptosis and the role of its agonist in cancer treatment.
total:1
The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases. 2006 to the paper
Abgent anti-LPA1 antibody was used to perform western blot in order to study the role of type 1 lysophosphatidic acid(LPA1) receptor in deal with bone metastases.
total:2
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. 2005 to the paper
LifeSpan Biosciences rabbit anti-human BLT1 receptor antibody was used in western blot and immunohistochemistry to study leukotriene B4 signaling in vascular smooth muscle cells in atherosclerosis and intimal hyperplasia more
total:1
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. 2005 to the paper
LifeSpan Biosciences rabbit anti-human BLT2 receptor antibody was used in immunohistochemistry to study leukotriene B4 signaling in vascular smooth muscle cells in atherosclerosis and intimal hyperplasia
total:1
Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor C-terminal tail. 2005 to the paper
Chemikon affinity-purified chicken anti-MCH-1 receptor antibody was used in immunocytochemistry to study the effect of periplakin on G protein activation by the melanin-concentrating hormone receptor-1
total:1
The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression. 2009 to the paper
Biomol NTS rabbit antibody was used in immunohistochemistry in order to investigate the role of neurotensin receptor-1 pathway in the regulation of human ductal breast cancer progression.
total:3
The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression. 2009 to the paper
Santa Cruz NTSR1 goat polyclonal antibody was used for immunohistochemistry in order to investigate the role of neurotensin receptor-1 pathway in the regulation of human ductal breast cancer progression. more
total:8
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. 2008 to the paper
Santa Cruz Biotechnology anti-orexin-B antibody (1:5,000) was used in immunohistochemistry in order to demonstrate that the Hcrt and N/OFQ systems interact to coordinately modulate SIA more
total:4
Prolactin activates mitogen-activated protein kinase signaling and corticotropin releasing hormone transcription in rat hypothalamic neurons. 2009 to the paper
Chemicon Temecula OT (oxytocin) monoclonal antibody was used in immunohistochemistry in order to investigate the mechanism for the prolactin-mediated hypothalamic pituitary adrenal axis inhibition during lactation in hypothalamic neurons. more
total:2
Constitutive and ligand-induced nuclear localization of oxytocin receptor. 2007 to the paper
Research Diagnostic polyclonal anti-OTR antibody directed towards the N-terminal was used in western blot to demostrate the constitutive and ligand-induced nuclear expression of oxytocin receptor. more
total:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-p110alpha was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:2
Possible role of extracellular nucleotides in ectopic ossification of human spinal ligaments. 2008 to the paper
Alomone Labs anti-P2Y1 antibody was used in western blot to study the role for extracellular nucleotides in ectopic ossification of human spinal ligaments in human cells. more
total:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Upstate anti-p85 pAb was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:7
Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. 2007 to the paper
Santa Cruz Biotechnology PAR1 antibody was used in immunohistochemistry to determine the expression and functions of PARs in the gallbladder epithelium. more
total:6
Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. 2007 to the paper
Santa Cruz Biotechnology PAR2 antibody was used in immunohistochemistry to determine the expression and functions of PARs in the gallbladder epithelium. more
total:2
A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. 2005 to the paper
Dr Stefan Feske anti-PLCgamma antibody was used in western blot to study the defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. more
total:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Millipore polyclonal anti-human p85 antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:35
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. 2009 to the paper
Santa Cruz Biotechnology anti-PKCdelta antibody was used in western blot to study the mechanism underlying PKCalpha suppressing tumor in the intestine. more
total:20
GABAA receptor trafficking is regulated by protein kinase C(epsilon) and the N-ethylmaleimide-sensitive factor. 2010 to the paper
Santa Cruz Biotechnology goat anti-PKC epsilon antibody was used to perform western blot and immunocytochemistry in order to show that NSF and PKC epsilon could regulate GABAA receptor trafficking to affect synaptic inhibition. more
- platelet activating factor receptor antibody
- platelet activating factor receptor gene knockdown
- platelet activating factor receptor cDNA
- platelet activating factor receptor protein
- platelet activating factor receptor inhibitor/activator/substrate/reporter
- platelet activating factor receptor ELISA/assay
- platelet activating factor receptor other
total:1
Relative levels of semen platelet activating factor-receptor (PAFr) and ubiquitin in yearling bulls with high content of semen white blood cells: implications for breeding soundness evaluation. 2007 to the paper
Cayman Chemicals PAF receptor antibody was used in western blot and immunohistochemistry to study the role of PAF receptor in fertility.
total:3
Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. 2005 to the paper
Santa Cruz Biotechnology PLC beta2 antibody was used in western blot to study localization of TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells more
total:5
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKC-eta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
total:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKCtheta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
total:1
The endocrine-gland-derived vascular endothelial growth factor (EG-VEGF)/prokineticin 1 and 2 and receptor expression in human prostate: Up-regulation of EG-VEGF/prokineticin 1 with malignancy. 2006 to the paper
R&D Systems anti-EG-VEGF (prokineticins) antibody (no. MAB1209) was used in protein and paraffin sections from human prostate, and which were used in western blot and immunohistochemistry, to study the expression of EG-VEGF/PK1 and PK2 and their receptors (PK-R1 and PK-R2) in human prostate and their involvement in cancer.
total:1
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway. 2010 to the paper
Lifespan Biosciences anti-PROKR1 polyclonal antibody was used to perform immunohistochemistry in order to study the modulation of IL11 expression by PROK1 via PROKR1 and the calcineurin/NFAT signalling pathway.
total:1
Uteroglobin inhibits prostaglandin F2alpha receptor-mediated expression of genes critical for the production of pro-inflammatory lipid mediators. 2005 to the paper
Cayman chemical rabbit polyclonal FP receptor antibody was used in western blot to determine FP protein expression in hUSM cells
total:2
High affinity choline transporter immunoreactivity in rat ileum myenteric nerves. 2007 to the paper
Santa Cruz goat Substance P antibody (1:50) was used in immunohistochemistry to localize CHT immunoreactivity (CHT-IR) within the rat ileum ENS and determined whether it colocalised with immunoreactivity for markers of cholinergic, tachykinergic, and nitrergic circuitry. more
total:4
Elimination of rat spinal substance P receptor bearing neurons dissociates cardiovascular and nocifensive responses to nicotinic agonists. 2008 to the paper
Chemicon anti-Substance P receptor (NK-1r) (1:1000 of source stock) antibody was used in immunohistochemistry to further characterize intrathecal (IT) delivery of nicotinic agonists. more
total:6
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC3 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
total:7
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC6 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
total:1
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. 2005 to the paper
Santa Cruz anti-TRPC7 antibody was used in western blot to study the role of endogenous TRPC6 channels in Ca2+ signal generation.