Fatty acid, triacylglycerol, and ketone body metabolism
gene
reagent
sample publication
sample review
total:10
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Abcam mouse monoclonal anti-ABCA1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
total:1
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Signet Laboratories mouse anti-MDR antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes.
total:17
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-ACC1 S79ph antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:2
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
Cayman ACAT-1 antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction. more
total:1
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate. 2008 to the paper
Novus Biologicals anti-Facl3 antibody was used for western blot in order to investigate the roles of elenium and isoflavones in the regulation of androgen-regulated gene expression in healthy rat dorsolateral prostate.
total:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 to the paper
IgG corporation rabbit polyclonal anti-ang II serum was used in immunohistochemistry in order to study the glomerular AGT's expression and its correlation with expression of other RAS components more
total:1
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. 2005 to the paper
Karen S. L. Lam (University of Hong Kong, China) monoclonal ANGPTL4 antibody was used in ELISA to study its effect in mice
total:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Abcam polyclonal rabbit anti-apoA-I antibody (1:10,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
total:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 to the paper
Epitomics anti-ATP-citrate lyase antibody was used to perform western blot in order to study the cytotoxicity of timosaponin AIII towards tumor cells.
total:3
The C-terminal domain of RNA polymerase II is modified by site-specific methylation. 2011 to the paper
Bethyl Laboratories anti-CARM1 antibody was used to perform immunocytochemistry in order to reveal that methylation of the carboxy-terminal domain of RNA polymerase II facilitates the expression of some RNAs. more
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:11
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Santa Cruz Biotechnologies CTGF antibody (1:2,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
total:1
Coimmunoprecipitation of FAT/CD36 and CPT I in skeletal muscle increases proportionally with fat oxidation after endurance exercise training. 2006 to the paper
Santa Cruz Biotechnology polyclonal antibody against CPT I was used in immunoprecipitation to isolate CPT I from human skeletal muscle.
total:15
Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. 2009 to the paper
Chemicon International anti-CYP 1A1 antibody (AB1258) was used in western blot to determine the functional significance of aryl hydrocarbon receptor (AhR) in gastric carcinogenesis, and to explore the possible role of AhR in gastric cancer (GC) treatment more
total:1
Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development. 2007 to the paper
Invitrogen DecR1 antibody was used in western blot to study the role of DecR1 in mammary tumor development.
total:1
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Santa Cruz anti-DGAT1 antibody was used in western blot, immunocytochemistry and immunoprecipitation to study the formation requirement of efficient hepatitis C virus particle.
total:2
One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. 2008 to the paper
Proteintech Group rabbit polyclonal anti-ECHS1 antibody was used for western blot in order to study the effect of altered proteome of morphologically normal colon crypts on familial adenomatous polyposis. more
total:1
Haploinsufficiency is not the key mechanism of pathogenesis in a heterozygous Elovl4 knockout mouse model of STGD3 disease. 2006 to the paper
Abcam rabbit polyclonal anti-ELOVL4 antibody was used in western blot to characterize a mouse model with a targeted deletion of Elovl4 and to explore the role of this gene in retinal/macular degeneration.
total:1
Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. 2010 to the paper
R&D Systems goat anti-human L-FABP polyclonal antibody was used to perform western blot in order to study the prognostic ability of urinary liver-type fatty acid-binding protein (L-FABP) in Acute kidney injury (AKI).
total:6
Fatty acid synthase expression in cutaneous melanocytic neoplasms. 2005 to the paper
Immuno-Biological Laboratories anti-fatty acid synthase antibody was used in immunohistochemistry to study expression of fatty acid synthase in cutaneous melanocytic neoplasms. more
total:4
Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway. 2009 to the paper
Santa Cruz Biotechnology anti-FHL2 antibody was used for western blot to study the suppressing role of human FHL1 family members in the modulation of tumor cell growth through a TGF-beta like signaling pathway. more
total:1
The Dickkopf-homolog 3 is expressed in tumor endothelial cells and supports capillary formation. 2008 to the paper
R&D systems mouse Dkk-3 monoclonal antibody was used to perform western blot in order to study the expression of Dkk-3 in various solid tumor types.
total:1
Central role of Gq in the hypertrophic signal transduction of angiotensin II in vascular smooth muscle cells. 2008 to the paper
Chemicon glyceraldehyde-3-phosphate dehydrogenase antibody was used in western blot in order to demonstrate that Gq coupling of the AT1 receptor is essential for the EGFR transactivation and subsequent VSMC hypertrophy induced by AngII
total:1
COMMD1 expression is controlled by critical residues that determine XIAP binding. 2009 to the paper
Stressgen anti-SCHAD was used to perform immunoprecipitation in order to show that the expression of COMMD1 is regulated while COMMD1 and XIAP interact with each other via some critical residues
total:1
Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity. 2011 to the paper
Lifespan Biosciences anti-HADHB antibody was used to perform western blot in order to reveal how viperin facilitates the infectious process.
total:21
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 to the paper
Santa Cruz Biotechnology anti-HDAC3 antibody was used to perform western blot assay in order to identify novel histone deacetylase complexes that promote expansions of trinucleotide repeats. more
total:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-HMGCR antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism.
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-MED1 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:15
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex. 2010 to the paper
Abcam anti-Sin3a trimethyl was used to perform western blot in order to study the role of deacetylase inhibitors to ING2 subunit from the Sin3 complex. more
total:6
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. 2006 to the paper
BD Biosciences mouse monoclonal anti-TIF2 antibody was used in western blot (1:500) and immunohistochemistry (1:500) to assess the consequences of reducing expression of the transcription intermediary factor 2 (TIF2) coactivator on prostate cancer cell growth. more
total:1
Characterization of activating signal cointegrator-2 as a novel transcriptional coactivator of the xenobiotic nuclear receptor constitutive androstane receptor. 2005 to the paper
anti-ASC-2 antibody was used in immunoprecipitation to study the characterization of activating signal cointegrator-2 as a novel transcriptional coactivator of the xenobiotic nuclear receptor constitutive androstane receptor.
total:14
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-p300 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:13
Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-NF-YA antibody was used in immunoblot in order to study the role of tuberin and OGG1 in the pathogenesis of angiomyolipoma in TSC patients. more
total:1
The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response. 2008 to the paper
Santa Cruz rabbit polyclonal anti-NPAS2 antibody was used to perform western blot in order to show that circadian gene NPAS2 is a putative tumor suppressor involved in DNA damage response.
total:1
Endurance exercise as a countermeasure for aging. 2008 to the paper
SantaCruz anti-NRF-1 antibody was used in western blot in order to investigate whether the mitochondrial dysfunction and reduced insulin sensitivity are inevitably caused by aging.
total:2
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Santa Cruz anti-ADRP antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:9
Integration of microRNA miR-122 in hepatic circadian gene expression. 2009 to the paper
Abcam rabbit polyclonal antibody PPAR was used for immunoprecipitation in order to study the circadian gene expression of integration of microRNA miR-122 in hepatic. more
total:4
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
R&D technologies anti-PRKAA2 antibody was used to carry out western blot analysis and ChIP assays in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:14
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 to the paper
Santa Cruz Biotechnology polyclonal RXRs antibody was used to perform western blot in order to clarify that retinoic acid could inhibit CYP4F11 expression in human keratinocyte-derived HaCaT cells by multiple signaling pathways including RXR and JNK pathways. more
total:11
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Affinity Bioreagents anti-SMRT antibody was used to perform western blot in order to show that IRF5 mediates the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:70
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene. 2010 to the paper
Santa Cruz anti-Sp1 antibody was used to perform ChIP assay in order to study the regulatory function of Sp1 and KLF15 on basal transcription of the human LRP5 gene. more
total:12
The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors. 2009 to the paper
Affinity BioReagents anti-SRC1 antibody was used in immunoprecipitation in order to investigate the cooperation between thyroid hormone receptor beta2 and p160 coactivator PAS-B through multiple contact surfaces. more
total:3
Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. 2005 to the paper
Santa Cruz Biotechnology anti-SREBP2 antibody was used in western blot to study the effect of liver X receptor alpha on SREBP1c-mediated Abcd2 expression more
total:11
Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 to the paper
NeoMarkers monoclonal SREBP-1 antibody was used in western blot in order to study the mechanism by which the activation of Wnt/beta-catenin signaling in skeletal muscle cells can improve insulin sensitivity. more
total:2
Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver. 2006 to the paper
Pan-Vera polyclonal rabbit anti-human SULT2A1 antibody was used in western blot to study the different expression pattern of hepatic SULT1A1, SULT1E1, and SULT2A1. more
total:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Mercury mouse anti-2, 2, 7-trimethylguanosine (TMG)antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing.
total:2
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. 2008 to the paper
EMD Chemicals anti-TRB3 antibody was used to perform western blot in order to study the response of the mTORC1 signaling after the inhibition of protein synthesis. more
total:2
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities. 2009 to the paper
Santa Cruz Biotechnology anti-TrxR1 antibody was used in western blot in order to show that adiponectin haploinsufficiency can promote mammary tumorigenesis through inhibition of PTEN activity and activation of PI3K/Akt signalling pathway. more