Fanconi anemia complementation groups
gene
reagent
sample publication
sample review
BRCA2
BRCA2 DNA repair associated
total:10
FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. 2010 to the paper
EMD anti-BRCA2 antibody was used to carry out immunofluorescence assays in order to investigate the role for FAN1 in promoting DNA interstrand cross-link repair by mono-ubiquitylating FANCI-FANCD2 complex. more
BRIP1
BRCA1 interacting protein C-terminal helicase 1
total:2
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Bethyl Laboratories anti-FANCJ was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
FANCA
FA complementation group A
total:2
ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function. 2009 to the paper
Cascade Bioscience anti-FANCA antibody was used in western blot in order to demonstrate that phosphorylation of FANCA on serine 1449 after DNA damage is downstream of ATR and is functionally important in the FA pathway. more
FANCD2
FA complementation group D2
total:9
FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. 2010 to the paper
Novus Biological anti-FANCD2 polyclonal antibody was used to carry out immunofluorescence assays in order to investigate the role for FAN1 in promoting DNA interstrand cross-link repair by mono-ubiquitylating FANCI-FANCD2 complex. more