Extracellular matrix organization
gene
reagent
sample publication
sample review
total:10
S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10. 2009 to the paper
Chemicon ADAM-10 antibody was used for western blot in order to indentify new biomarker of Alzheimer's disease. more
total:4
Activin receptor signaling regulates prostatic epithelial cell adhesion and viability. 2009 to the paper
Chemicon International ADAM-15 was used to recognize the C-terminus amino acid sequence RPAPPPPAASSLYL in order to study the mechanism of activin receptor signaling regulating prostatic epithelial cell adhesion and viability more
total:13
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. 2008 to the paper
Santa Cruz Biotechnology anti-TACE antibody was used to perform Western Blot in order to show that TACE has a inhibitory role in EGFR axis in colorectal cancer. more
total:3
The detection of ADAM8 protein on cells of the human immune system and the demonstration of its expression on peripheral blood B cells, dendritic cells and monocyte subsets. 2007 to the paper
R&D Systems mouse anti-human ADAM8 antibody (1:2500 dilution) was used in western blot to study the role of ADAM8 in allergic responses. more
total:6
Human parainfluenza virus type 2 (HPIV2) induced host ADAM8 expression in human salivary adenocarcinoma cell line (HSY) during cell fusion. 2009 to the paper
Triple Point Biologics polyclonal rabbit anti-human ADAM9 antibody was used in immunocytochemistry to investigate expression of ADAMs of host cell origin during cell-cell fusion induced by human parainfluenza virus type 2 more
total:2
Vascular endothelial growth factor upregulates expression of ADAMTS1 in endothelial cells through protein kinase C signaling. 2006 to the paper
Sigma Chemical abbit polyclonal C-terminal of human anti ADAMTS1 antibody was used in western blot to study the regulation of ADAMTS1 expression in endothelial cells by vascular endothelial growth factor (VEGF). more
total:2
Vascular endothelial growth factor upregulates expression of ADAMTS1 in endothelial cells through protein kinase C signaling. 2006 to the paper
Sigma Chemical abbit polyclonal C-terminal of human anti ADAMTS1 antibody was used in western blot to study the regulation of ADAMTS1 expression in endothelial cells by vascular endothelial growth factor (VEGF). more
total:1
The regulation of aggrecanase ADAMTS-4 expression in human Achilles tendon and tendon-derived cells. 2008 to the paper
Serotec ADAMTS-4 were used in western blot in order to study the effects of growth factors on the regulation of ADAMTS-4 expression
total:1
The regulation of aggrecanase ADAMTS-4 expression in human Achilles tendon and tendon-derived cells. 2008 to the paper
Serotec ADAMTS-4 were used in western blot in order to study the effects of growth factors on the regulation of ADAMTS-4 expression
total:4
Expression of ZIC family genes in meningiomas and other brain tumors. 2010 to the paper
Sigma anti-chondroitin sulfate proteoglycan antibody was used to perform immunohistochemistry in order to study the expression of the ZIC family genes in different type of brain tumors. more
total:1
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Invitrogen rabbit IgG was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models.
total:13
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 to the paper
Santa Cruz anti-ACTN1 antibody was used for western blot in order to investigate the role of CaMKII in the regulation of pressure overload-induced cardiac hypertrophy to heart failure in mice. more
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
total:7
A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. 2008 to the paper
Santa Cruz Biotechnology anti-BMP7 antibody was used in immunohistochemistry to identify these TGFbeta family members in human endometrium, and to determine whether they are involved in human decidualization. more
total:1
Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation. 2005 to the paper
Affinity Bioreagents polyclonal anti-BMP-1 antibody (recognizing the CUB-2 domain) was used in western blot to study the binding of cellular fibronectin with lysyl oxidase
total:8
A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. 2008 to the paper
Santa Cruz Biotechnology anti-BMP2 antibody was used in immunohistochemistry to identify these TGFbeta family members in human endometrium, and to determine whether they are involved in human decidualization. more
total:9
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. 2006 to the paper
Santa cruz biotechnology anti-BMP4 antibody was used to perform western blot and immunohistochemistry assays in order to investigate the molecular regulation mechanisms of Smad4 in the process of normal pancreas development and pancreatic ductal adenocarcinomas (PDAC) growth. more
total:8
Ethanol enhances tau accumulation in neuroblastoma cells that inducibly express tau. 2008 to the paper
Santa Cruz anti-Vcalpain-1 antibody was used to perform western blot in order to show that ethanol can induce the expression and accumulation of tau in neuroblastoma cells. more
total:1
PPIB mutations cause severe osteogenesis imperfecta. 2009 to the paper
Santa CruzCRTAPantibody was used to perform immunohistochemistry in order to investigate the relation between OI and CRTAP
total:1
Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation. 2007 to the paper
Santa Cruz Biotechnology anti-COMP antibody was used in immunohistochemistry diluted at 1:200 to define the biological functions of COMP and its relationship with GEP.
total:6
SUMOylation of the MAGUK protein CASK regulates dendritic spinogenesis. 2008 to the paper
Santa Cruz rabbit polyclonal anti-CASK was used to perform western blot in order to show that dendritic spinogenesis is regulated by SUMOylation of the MAGUK protein CASK. more
total:212
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Abcam Caspase-3 antibody was used to perform immunohistochemistry in order to study theeffect of thiabendazole on proliferation and apoptosis of human cells. more
total:14
Acid sphingomyelinase activity triggers microparticle release from glial cells. 2009 to the paper
Chemicon rabbit polyclonal anti-Cathepsin B Ab (1:200) was used in western blot in order to study the activation of acid sphingomyelinase in microparticle release from glial cells. more
total:13
Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. 2009 to the paper
Santa Cruz Biotechnology primary anti-cathepsin D (H-75) was used to detect endogenous lysosomal and ER proteins by immunohistochemistry method in order to study the preferentially expressed characterization of the arylsulfatase I (ARSI) gene. more
total:8
Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function. 2008 to the paper
Calbiochem of EMD Bioscience Inc. anti-cathepsin L antibody was used in western blot to study the effect of the role for Anaplasma phagocytophilum in increasing cathepsin L activity on neutrophil function. more
total:46
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Beckman-coulter PE-conjugated anti-CD11b was used to perform flow cytometry in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:25
Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1. 2012 to the paper
BioLegend anti-CD11c monoclonal antibody was used to perform FACS in order to study novel HIV-1 capture mechanism. more
total:15
Upregulation of EMMPRIN after permanent focal cerebral ischemia. 2008 to the paper
Serotec rat anti-EMMPRIN monoclonal antibody (1:200) was used in immunohistochemistry in order to examine potential association between EMMPRIN and MMP-9 expre more
total:23
CBFbeta is critical for AML1-ETO and TEL-AML1 activity. 2009 to the paper
eBioscience allophycocyanin (APC), phycoerythrin (PE), or PerCPcy5.5 conjugated anti Mac-1 (clone M1/70) antibody was used in flow cytometry in order to determine whether CBFbeta is required for AML1-ETO and TEL-AML1 activity more
total:13
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD41 was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:49
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Millipore rat anti-heparan sulfate proteoglycan monoclonal antibody was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models. more
total:4
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
BD Biosciences anti-CD47 was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:56
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD56 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
total:1
Stanniocalcin 1 acts as a paracrine regulator of growth plate chondrogenesis. 2006 to the paper
Santa Cruz Biotechnology rabbit polyclonal collagen X antibody was used in immunohistochemistry to study the effects of rhSTC on collagen X expression in control and STC-treated metatarsal bones
total:2
Pathophysiological role of poly(ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice. 2005 to the paper
Molecular Probes anti-nitrotyrosine antibody was used in immunohistochemistry to evaluate a pathophysiological role of PARP-1. more
total:8
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 to the paper
Developmental Studies Hybridoma Bank anti-collagen-I antibody was used to perform western blot in order to investigate the mechanism of Golgi-mediated protein traffic. more
total:1
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
Abcam mouse anti -COL21A1 polyclonal antibody(1:750)was used to perform western blot in order to study the function of quiescent fibroblasts.
total:9
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
Abcam anti Col IV antibody was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
total:5
Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. 2005 to the paper
Santa Cruz Biotechnology goat anti-alpha3 antibody was used in western blot to study the effect of activation of vascular endothelial growth factor receptor 3 on endothelial function and infection. more
total:2
ELR-negative CXC chemokine CXCL11 (IP-9/I-TAC) facilitates dermal and epidermal maturation during wound repair. 2008 to the paper
Abcam rabbit polyclonal collagen IV antibody was used in immunohistochemistry in order to study the role of IP-10 and IP-9 in epidermal maturation during wound repair more
total:4
Comparison between human fetal and adult skin. 2010 to the paper
Dako anti-Collagen type IV was used to perform immunohistochemistry in dilution 1:250 in order to show that dermal components express differentially between human fetal and adult skin and play important roles in fetal scarless healing. more
total:2
The extracellular matrix glycoprotein elastin microfibril interface located protein 2: a dual role in the tumor microenvironment. 2010 to the paper
Santa Cruz Biotechnology anti-type I collagen antibody was used in western blot in order to investigate the function of the 90-amino acid residue fragment of elastin microfibril interface located protein 2 (EMILIN2) in the tumor microenvironment. more
total:2
Alteration of medial-edge epithelium cell adhesion in two Tgf-beta3 null mouse strains. 2008 to the paper
Developmental Studies Hybridoma Bank 1:50 monoclonal mouse IgG anti-sheep collagen IX antibody was used in immunohistochemistry in order to study the role of growth factor TGF-b3 in palatal shelf adhesion more
total:4
T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. 2009 to the paper
Abcam goat polyclonal anti-cathepsin S was used to block and incubate the blots in order to suggest that T-cell activation can limits collagen maturation in the atherosclerotic plaque. more
total:2
Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification. 2006 to the paper
R&D Systems monoclonal mouse-anti-human CTSV antibody was used in immunohistochemistry to study cystatin M/E as a high affinity inhibitor of cathepsin V and cathepsin L through a reactive site that is distinct from the legumain-binding site more
total:5
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
Hycult Biotech anti ADG antibody was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
total:8
Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. 2009 to the paper
R&D Systems anti-NEP antibody was used in immunohistochemistry in order to investigate the role of neprilysin in the regulation of pulmonary vascular remodeling in response to chronic hypoxia. more
total:1
Discoidin domain receptor 2 mediates tumor cell cycle arrest induced by fibrillar collagen. 2005 to the paper
Regeneron Pharmaceuticals polyclonal anti-DDR2 antibody (R2-JM) was used in western blot to study a novel direct mechanism by which cell contact with fibrillar collagen restricts proliferation.
total:1
Inhibition of human dental pulp stem cell differentiation by Notch signaling. 2008 to the paper
NIDCR/NIH polyclonal antibody against DSPP was used to perform western blot in order to investigate the role of Notch signaling pathway during human dental pulp stem cell differentiation.
total:8
Long-term survival of transplanted stem cells in immunocompetent mice with muscular dystrophy. 2008 to the paper
Novacastra anti-dystrophin mouse monoclonal antibody NCL-DYS2 was used in immunohistochemistry at 1:100 in order to study the role of duchenne muscular dystrophy in the long-term survival of transplanted stem Cells more
total:129
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Invitrogen rat anti-E-Cadherin (ECCD-2; 13-1900) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
total:11
Mycobacterial disease and impaired IFN-? immunity in humans with inherited ISG15 deficiency. 2012 to the paper
Abcam anti-elastase antibody was used to perform western blot and immunocytochemistry in order to show that ISG15 deletion in humans impairs IFN-gamma immunity and results in mycobacterial disease susceptibility. more
total:11
Mycobacterial disease and impaired IFN-? immunity in humans with inherited ISG15 deficiency. 2012 to the paper
Abcam anti-elastase antibody was used to perform western blot and immunocytochemistry in order to show that ISG15 deletion in humans impairs IFN-gamma immunity and results in mycobacterial disease susceptibility. more
total:3
Comparison between human fetal and adult skin. 2010 to the paper
Sigma anti-elastin was used to perform immunohistochemistry in dilution 1:500 in order to show that dermal components express differentially between human fetal and adult skin and play important roles in fetal scarless healing. more
total:4
Reduction of endogenous angiogenesis inhibitors in Bruch's membrane of the submacular region in eyes with age-related macular degeneration. 2008 to the paper
R&D Systems anti-endostatin antibody was used to perform immunohistochemistry in order to study the level of angiogenesis inhibitors in eyes with age-related macular degeneration. more
total:2
Fibulin-5 mutations: mechanisms of impaired elastic fiber formation in recessive cutis laxa. 2006 to the paper
Chemicon mouse monoclonal antibody against Fibrillin-1 was used in immunocytochemistry to investigate the association of fibulin-5 with Fibrillin-1 in patient fibroblasts more
total:1
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 to the paper
Behring rabbit anti-fibrinogen antibody was used to carry out immunofluorescence assays in order to investigate the association for increased expression of urokinase plasminogen activator and megakaryocyte differentiation in Quebec platelet disorder.
total:20
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 to the paper
Chemicon rabbit polyclonal anti-FGF2 antibody was used in western blot to study the role for endothelial-derived FGF2 in the progression of pulmonary hypertension in humans and rodents. more
total:4
Biomarkers for ragwort poisoning in horses: identification of protein targets. 2008 to the paper
Affiland rabbit (polyclonal) anti-(equine) fibrinogen antibody was used in western blot in order to investigate whether pyrrole toxins induce specific modifications of equine blood proteins that are detectable by proteomic methods more
total:39
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. 2010 to the paper
Sigma Aldrich anti-fibronectin antibody was used to perform immunocytochemistry and western blot in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors. more
total:2
A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. 2008 to the paper
Santa Cruz Biotechnology anti-GDF5 antibody was used in immunohistochemistry to identify these TGFbeta family members in human endometrium, and to determine whether they are involved in human decidualization. more
total:30
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. 2011 to the paper
R&D systems anti-ICAM-1 antibody was used to perform immunocytochemistry in order to study the remodelling of cortical actin at natural killer cell immune synapses. more
total:2
ICAM-2 expression mediates a membrane-actin link, confers a nonmetastatic phenotype and reflects favorable tumor stage or histology in neuroblastoma. 2008 to the paper
R&D Systems anti-ICAM-2 antibody was used for western blot in order to investigate the role of ICAM-2 in the mediation of membrane-actin link in neuroblastoma. more
total:24
TGFBI expression is associated with a better response to chemotherapy in NSCLC. 2010 to the paper
Chemicon Interational anti-integrin alphavbeta3 monoclonal was used to perform flow cytometry in order to determine if this integrin influences TGFBI-mediated NSCLC cell susceptibility to chemotherapy. more
total:15
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha2 antibody (clone P1E6) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
total:16
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
Millipore anti-integrin alpha 3 antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
total:30
The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis. 2008 to the paper
Chemicon monoclonal anti-alpha5 was used to perform blocking experiments in order to show that integrins could interact with CXCL4 and play a role in angiogenesis. more
total:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal integrin beta3 antibody (1:1000) was used in western blot in order to study the role of activated state of p42/44 and p38 in MMP-13 expression. more
total:8
Binding of the Streptococcus gordonii DL1 surface protein Hsa to the host cell membrane glycoproteins CD11b, CD43, and CD50. 2008 to the paper
R&D Systems anti-CD50 (1:250) antibody was used in western blotting in order to investigate the binding of the Streptococcus gordonii DL1 surface protein Hsa to the host cell membrane glycoproteins CD11b, CD43, and CD50 more
total:11
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha1 antibody (clone FB12) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
total:7
Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells. 2009 to the paper
eBioscience antibodies against alpha4beta1 were used in immunohistochemistry to investigate MuPAR and plasmin in the regulation of the proliferation, marrow pool size, homing, engraftment, and mobilization of HSPCs and HSCs. more
total:20
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD49f-PE antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
total:1
Analysis of integrin alpha7 mutations in prostate cancer, liver cancer, glioblastoma multiforme, and leiomyosarcoma. 2007 to the paper
Novus Biologicals Inc mouse anti integrin 7 monoclonal antibody was used in western blot, immunoprecipitation, and immunohistochemistry to study the role of integrin 7 in human malignancies.
total:5
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 to the paper
Proteintech Group anti-RLC antibody was used to perform western blot in order to study the assemble of mammalian nonmuscle myosin II in live cells. more
total:2
Loss of CD103+ intestinal dendritic cells during colonic inflammation. 2010 to the paper
BD Pharmingen CD103 antibody was used for FACS analysis in order to investigate possible differences in dendritic cells within intestinal tissue of mice before and after induction of colitis. more
total:12
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-ITGB4 antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
total:9
Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation. 2008 to the paper
Chemicon alphaVbeta5 mAb was used to perform immunoblotting in order to illustrate that transforming growth factor, beta-induced (beta ig-h3/TGFBI) could enhance the aggressiveness and alter the metastatic properties of colon cancer cells in vivo. more
total:1
Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6. 2007 to the paper
Biogen Idec monoclonal antibody 6.2E5 was used for western blotting, immunofluorescence, and immunohistochemistry (1 ug/ml) and 6.3G9 (a function-blocking antibody) was used for the migration and soft-agar assays (30 ug/ml) and for flow cytometry to study the induction of tumorigenesis and enhancement of cell motility of prostate epithelial cells by constitutively activated Stat3 through integrin beta 6.
total:1
Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exit. 2010 to the paper
Michel Aurrand-Lions anti-myc monoclonal antibody was used to perform western blot in order to study that during germinal zone exit siah regulation of Pard3A controls neuronal cell adhesion
total:1
Premature terminal differentiation and a reduction in specific proteases associated with loss of ABCA12 in Harlequin ichthyosis. 2009 to the paper
Santa Cruz anti-KLK7 antibody was used to perform immunohistochemistry in order to study the morphological and biochemical alterations associated with the loss of ABCA12 in harlequin ichthyosis.
total:4
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
Abnova mouse anti-LAMA2 polyclonal antibody was used to perform western blot in order to study the function of quiescent fibroblasts. more
total:3
Nephrotic syndrome and aberrant expression of laminin isoforms in glomerular basement membranes for an infant with Herlitz junctional epidermolysis bullosa. 2005 to the paper
Chemicon monoclonal anti-laminin alpha3 chain antibody P3H9 was used in immunohistochemistry to study the association of laminin isoforms with herlitz junctional epidermolysis bullosa in a case complicated by nephrotic syndrome. more
total:9
Analysis of human muscle stem cells reveals a differentiation-resistant progenitor cell population expressing Pax7 capable of self-renewal. 2009 to the paper
Santa Cruz goat anti-laminin 1 sc6016 was used to perform flow cytometry in order to study the role of Pax7 in human satellite stem cell differentiation and self renewal. more
total:4
Overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases. 2005 to the paper
Developmental Studies Hybridoma Bank mouse monoclonal anti-Laminin beta2 chain antibody was used in western blot and immunohistochemistry to study the overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases. more
total:6
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
Millipore anti-laminin gamma 2 chain antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
total:16
Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle. 2008 to the paper
Chemicon rabbit polyclonal laminin antibody was used in immunohistochemistry in order to study the role of talin 1 in the development and function of skeletal muscle more
total:1
PPIB mutations cause severe osteogenesis imperfecta. 2009 to the paper
AbnovaP3H1 antibody was used to perform immunohistochemistry in order to investigate the relation between OI and P3H1
total:14
Altered gene expression in early atherosclerosis is blocked by low level apolipoprotein E. 2008 to the paper
eBioscience CD11a antibody was used in immunohistochemistry in order to study the linkage between changes of adhesion molecules/cofactors and atherosclerosis more
total:1
Latent transforming growth factor-beta-binding protein-4 regulates transforming growth factor-beta1 bioavailability for activation by fibrogenic lung fibroblasts in response to bleomycin. 2009 to the paper
Santa Cruz Biotechnology LTBP-4 antibody was used for Western blotting and immunohistochemical staining in order to suggest that LTBP-4 can regulate latent TGF beta1 activation in bleomycin-induced lung fibrosis.
total:4
Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young rats. 2005 to the paper
Santa Cruz Biotechnology rabbit TGF-beta1 antibody was used in immunohistochemistry (1:50) to demonstrate that the remodeling of the common carotid artery with advancing age in Ang II untreated rats resembles that of the aorta. more
total:2
T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. 2009 to the paper
Novus Biologicals rabbit polyclonal anti-LOX was used to block and incubate the blots in order to suggest that T-cell activation can limits collagen maturation in the atherosclerotic plaque. more
total:2
Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells. 2005 to the paper
Oncogene Research Products monoclonal antibody against human MAdCAM-1 was used in western blot to study the mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells. more
total:13
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 to the paper
Calbiochem anti-MMP-1 monoclonal antibody was used to perform western blot in order to study the role of CD147 promoted myofibroblast differentiation in tissue remodeling. more
total:13
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 to the paper
Calbiochem anti-MMP-1 monoclonal antibody was used to perform western blot in order to study the role of CD147 promoted myofibroblast differentiation in tissue remodeling. more
total:13
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 to the paper
Calbiochem anti-MMP-1 monoclonal antibody was used to perform western blot in order to study the role of CD147 promoted myofibroblast differentiation in tissue remodeling. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:8
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-3 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
total:8
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-3 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
total:9
Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma. 2010 to the paper
Santa Cruz Biotechnology anti-MMP7 antibody was used in immunohistochemistry to investigate the function of UPK1A in esophageal squamous cell carcinoma. more
total:6
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
Chemicon MMP-8 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
total:5
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
R&D Systems anti-MMP-10 antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
total:5
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
R&D Systems anti-MMP-10 antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
total:4
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
R/D Systems MMP-12 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more
total:7
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-13 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
total:7
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-13 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
total:3
Opposing effects of interferon-alpha and interferon-gamma on the expression of major histocompatibility complex class I chain-related A in tumors. 2008 to the paper
Santa Cruz Biotechnology anti-MT2-MMP antibody was used to perform western blot in order to study the differential effects of IFN-alpha and IFN-gamma on tumor cells. more
total:1
Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling. 2006 to the paper
Triple Point Biologics MT3-MMP antibody was used in western blot in order to demonstrate that tumor cells require coordinate regulation of LPA/S1P receptors and Rho GTPases to migrate, and additionally, require MT1-MMP in order to invade collagen matrices during neoplastic progression.
total:4
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
Triple Point Biologics MMP-19 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more
total:1
Local and systemic responses in matrix metalloproteinase 8-deficient mice during Porphyromonas gingivalis-induced periodontitis. 2009 to the paper
Sigma-Aldrich Co. MMP-25 antibody was used in paraffin-embeded tissue specimens in immunostaining in order to research the role of MMP-8 in Porphyromonas gingivalis-induced periodontitis.
total:15
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 to the paper
Acris anti-MMP14(113-5B7) antibody was used to perform immunohistochemistry in order to study the expression of cytokeratin 7 and 19 are related with genomic stability and favorable prognosis in clear cell renal cell cancer. more
total:10
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 to the paper
Calbiochem rabbit anti-nicastrin antibody was used to perform western blot in order to study the effect of TNF-alpha on gamma-secretase. more
total:1
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
R&D Systems anti-nidogen-1 antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas.
total:12
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Calbiochem anti-osteopontin antibody (1:100) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:12
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Calbiochem anti-osteopontin antibody (1:100) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:16
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 to the paper
Novus Biologicals goat anti-human plasminogen antibody was used to perform ELISA in order to investigate the interaction between leptospiral endostatin-like protein A and human plasminogen. more
total:5
Antiangiogenic characteristics of astrocytes from optic nerve heads with primary open-angle glaucoma. 2008 to the paper
Santa Cruz Biotechnology anti-PDGF-A polyclonal antibody was used to perform western blot in order to study the role of astrocytes on angiogenesis. more
total:5
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-PDGF-B antibody was used in immunohistochemistry to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms. more
total:125
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Millipore anti-mouse CD31 antibody was used to perform immunohistochemistry in order to study the inhibition of antifungal drug thiabendazole to tumor growth in a mouse xenograft model. more
total:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 to the paper
Chemicon monoclonal anti-perlecan antibody (MAB 1948) was used in frozen sections from mouse and in immunohistochemistry to study the identification of WARP as a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. more
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
total:4
Borrelia burgdorferi infection-associated surface proteins ErpP, ErpA, and ErpC bind human plasminogen. 2009 to the paper
Novus Biologicals goat anti-human plasminogen antibody was used to perform ELISA in order to study human plasminogen binding surface proteins ErpP, ErpA, and ErpC in Borrelia burgdorferi infection. more
total:5
Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength. 2009 to the paper
Epitomics rabbit monoclonal anti-plectin antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the function for beta3 integrin-mediated vimentin IF recruitment to the cell surface. more
total:9
MyosinVIIa interacts with Twinfilin-2 at the tips of mechanosensory stereocilia in the inner ear. 2009 to the paper
Proteintech polyclonal antibody raised against the whole protein was used to perform western blot in order to investigate the relations of OI and CyPB more
total:6
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 to the paper
Abcam anti-PDIA1 antibody was used to perform western blot in order to study the role of non-directed activity-based protein profiling plays in the identification of enzymes that are either predominantly or exclusively labeled in living cells. more
total:12
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 to the paper
Chemicon rabbit anti-APP C-terminal antibody and mouse anti-APP (6E10) antibody were used to perform western blot in order to study the effect of TNF-alpha on gamma-secretase. more
total:1
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. 2011 to the paper
R&D Systems anti-RPTP sigma antibody was used to perform immunocytochemistry in order to study the role of receptor protein tyrosine phosphatase sigma in sensory neuron extension.
total:2
Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells. 2005 to the paper
Seikagaku HSPG neo-epitope (exposed after heparitinase III digestion, clone 3G10) antibody was used in western blot to study thrombin-induced human vascular smooth muscle cell migration and proliferation more
total:1
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue. 2006 to the paper
Zymed Laboratories rabbit anti syndecan-3 antibody was used in immunohistochemistry to study its expression in human uterine tissue during prolonged labour
total:3
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans. 2008 to the paper
Santa Cruz Biotechnology anti-syndecan-4 antibody was used in immunocytochemistry to study the effect of heparanase on cell adhesion and spreading. more
total:4
Regulatory role of FGF-2 on type I collagen expression during endothelial mesenchymal transformation. 2005 to the paper
Stressgen Biotechnologies mouse anti-Hsp47 antibody was used in immunohistochemistry to investigate the regulatory role of FGF-2 on type I collagen expression during endothelial mesenchymal transformation (EMT). more
total:11
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Santa Cruz Biotechnology anti-human SPARC antibody was used for western blot and immunohistochemistry in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:4
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
Chemicon MMP-11 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
total:4
trans-3,4'-Dimethyl-3-hydroxyflavanone, a hair growth enhancing active component, decreases active transforming growth factor beta2 (TGF-beta2) through control of urokinase-type plasminogen activator (uPA) on the surface of keratinocytes. 2008 to the paper
TECHNE anti-TGF-b2 antibody (which is in a ELISA assay kit) was used in ELISA to study the mechanism of hair growth enhancement by t-flavanone in human cells. more
total:5
Transforming growth factor-beta regulates in vitro heart valve repair by activated valve interstitial cells. 2008 to the paper
Abcam rabbit anti-TGF-beta3 antibody (1:100) was used in immunocytochemistry in order to investigate the regulatory role of transforming growth factor-beta in valve interstitial cell function during wound repair more
total:20
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. 2009 to the paper
Acbam mouse monoclonal antibody against human and mouse thrombospondin-1 was used in immunohistochemistry to investigate the role of transforming growth factor Beta signaling in the regulation of tumor growth. more
total:16
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
R/D Systems TIMP-1 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more
total:12
Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism. 2008 to the paper
Chemicon International mouse anti-human TIMP-2 antibody was used to perform western blot in order to investigate the role of MT1-MMP-TIMP-2 interaction in controlling cell functions. more
total:2
Expression of Toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis. 2008 to the paper
Santa Cruz Biotechnology rabbit TLR2 polyclonal antibody(1:10) was used to perform immunohistochemistry in order to investigate the expression of TLR2, TLR4, and their transmembrane coreceptor CD14 in the intestinal mucosa of terminal ileum. more
total:12
Limbal epithelial crypt: a model for corneal epithelial maintenance and novel limbal regional variations. 2008 to the paper
Santa Cruz Biotechnology anti-tenascin C antibody was used to perform immunohistochemistry in order to study the distribution of cell membrane proteins and extracellular matrix proteins in human corneoscleral limbus rims. more
total:4
Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of keratoepithelin. 2005 to the paper
Dako polyclonal anti-transthyretin antibody was used in immunohistochemistry to study the association of hereditary lattice corneal dystrophy with corneal amyloid deposits enclosing C-terminal fragments of feratoepithelin. more
total:11
Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis. 2010 to the paper
Abcam anti-tryptase was used to perform immunohistochemistry and immunocytochemistry in order to show that the levels of human neutrophil peptides 1-3 secretion is inhibited by tumor necrosis factor and norepinephrine in mixed synovial tissue cultures from osteoarthritis and rheumatoid arthritis patients. more
total:21
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. 2010 to the paper
Abcam anti-collagen I antibody was used to perform immunohistochemistry and immunocytochemistry in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors. more
total:15
A stem cell-based approach to cartilage repair. 2012 to the paper
Abcam anti-type II collagen antibody was used to perform immunocytochemistry in order to show that kartogenin could be used to induce chondrocyte differentiation for osteoarthritis treatment. more
total:13
TNF-alpha regulates the effects of irradiation in the mouse bone marrow microenvironment. 2010 to the paper
Chemicon anti-collagen IV antibody was used to carry out dot-blotting analysis in order to investigate the role of TNF-a in irradiation-induced bone marrow cell apoptosis and bone marrow dysfunction. more
total:19
The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. 2009 to the paper
Immunotech anti-VCAM-1 antibody was used in blocking or activating expriments to study the role for prostate specific membrane antigen in regulating the expression of IL-6 and CCL5 in prostate tumour cells. more
total:4
Expression of ZIC family genes in meningiomas and other brain tumors. 2010 to the paper
Sigma-Aldrich anti-chondroitin sulfate proteoglycan antibody was used to perform immunohistochemistry in order to investigate the expression profiles of ZIC genes in brain tumors. more
total:35
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling.. 2010 to the paper
Santa Cruz anti-Flk-1 antibody was used to perform immunoprecipitation in order to reveal the critical role of prorenin receptor and vacuolar H+-ATPase-mediated acidification in Wnt signaling. more
total:4
The effect of RGD peptides on osseointegration of hydroxyapatite biomaterials. 2008 to the paper
Santa Cruz vitronectin antibody was used in western blot in order to study the effect of RGD peptides on osseointegration of hydroxyapatite biomaterials more