Epigenetic regulation of gene expression
gene
reagent
sample publication
sample review
total:3
Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. 2005 to the paper
Santa Cruz Biotechnology cyclin H antibody was used in western blot to study the role of Dmp1 in Ras-Raf-Arf signaling. more
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK7 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:12
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-DNMT1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:5
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Epigentek anti-DNMT3a antibody was used for ChIP assays in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:5
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Epigentek anti-DNMT3b antibody was used for ChIP assays in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:3
The polycomb repressive complex 2 is a potential target of SUMO modifications. 2008 to the paper
Upstate mouse anti-EED AA19 was used to perform western blot in order to show that the polycomb repressive complex 2 could be sumoylated post-translationally. more
total:3
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-XPD was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:5
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-XPB was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:11
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. 2009 to the paper
Abcam anti-EZH2 was used to perform western blot in order to show the effects of G9a/KMT1C and jumonji-C type histone demethylases in histone H1 isotype 4 methylation and demethylation. more
total:1
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. 2009 to the paper
Santa Cruz Biotechnology TFIIH antibody was used in western blot to study the regulation of aromatase transcription and estrogen biosynthesis in adipose stromal cells (ASCs).
total:1
Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. 2007 to the paper
Dr. Peter Cheung (Ontario Cancer Institute) rabbit H2A.Z-specific antibodies (the H2A.Z-L1 antibody was raised against the peptide sequence KSSRTTSHGR, and the H2A.Z-C antibody was raised against the peptide sequence IPHIHKSLIGKKGQQKTV) was used in western blot and immunocytochemistry to study H2A.Z monoubiquitylation as the marker for its association with euchromatin or facultative heterochromatin
total:62
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Millipore Gamma-H2AX antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:32
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-H3K4 antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
total:5
Hsp90alpha recruited by Sp1 is important for transcription of 12(S)-lipoxygenase in A431 cells. 2005 to the paper
Upstate Biotechnology acetyl-H3 antibody was used in ChIP assay to study 12 (S) Lipoxygenase transcription in A431 cells more
total:11
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Active Motif anti-H4K12Ac antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:54
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-HDAC1 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:24
High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo. 2009 to the paper
Abcam anti-HDAC2 antibody was used to perform immunohistochemistry in order to study the association between the high class I HDAC activity and RelA/p65 activation in pancreatic cancer. more
total:1
Testis/sperm-specific histone 2B in the sperm of donors and subfertile patients: variability and relation to chromatin packaging. 2007 to the paper
Chemicon International TSH2B antibody was used in western blot to assesse the association of TSH2B with chromatin compaction status.
total:1
p53 chromatin epigenetic domain organization and p53 transcription. 2009 to the paper
Abcam anti-histone H2Bantibody was used to perform immunoprecipitation in order to demonstrate that physical barrier due to the folding of chromatin in domain II can give rise to the depletion of RNA polymerase II.
total:5
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Abcam anti-Histone 3, anti-H3 K9Me, and anti-H3 S10ph antibodies were used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:6
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Abcam anti-H2A antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:10
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-H2B antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:1
TAF1B is a TFIIB-like component of the basal transcription machinery for RNA polymerase I. 2011 to the paper
Santa Cruz goat polyclonal anti-TAF1D was used to perform western blot in order to show that Pol I transcription requires TAF1B for the recruitment of RNA polymerase I.
total:2
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". 2006 to the paper
Santa Cruz monoclonal anti-Mat1 antibody (F-6) was used in human T98G cells and in western blot to study the role for cyclins and CDK "inhibitors" in Thr172 phosphorylation of CDK4. more
total:15
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex. 2010 to the paper
Abcam anti-Sin3a trimethyl was used to perform western blot in order to study the role of deacetylase inhibitors to ING2 subunit from the Sin3 complex. more
total:1
TAF1B is a TFIIB-like component of the basal transcription machinery for RNA polymerase I. 2011 to the paper
Santa Cruz mouse monoclonal anti-Pol I subunits A190 was used to perform western blot in order to show that Pol I transcription requires TAF1B for the recruitment of RNA polymerase I.
total:6
CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene. 2006 to the paper
Abcam RbAp46 antibody was used in immunoprecipitation to study the molecular mechanism (s) by which CTIP2 contributes to T cell development and axonal. more
total:8
The polycomb repressive complex 2 is a potential target of SUMO modifications. 2008 to the paper
Upstate rabbit anti-RbAp48 13D10 was used to perform western blot in order to show that the polycomb repressive complex 2 could be sumoylated post-translationally. more
total:1
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Affinity Bioreagents anti-mSin3a antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs.
total:2
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex. 2010 to the paper
Upstate anti-Sap30 trimethyl was used to perform Chromatin immunoprecipitation in order to study the role of deacetylase inhibitors to ING2 subunit from the Sin3 complex. more
total:13
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Abcam anti-SIRT1 was used to perform western blot in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:4
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Bethyl Laboratories SNF2H antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:6
Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. 2008 to the paper
Cell Signaling anti-human SUV39H1 antibody was used to perform western blot in order to study the role of lysine methylation of HIV-1 Tat in transcriptional activity of the viral LTR. more
total:9
Long noncoding RNA as modular scaffold of histone modification complexes. 2010 to the paper
Abcam rabbit anti-SUZ12 antibody was used to carry out ChIP assays in order to investigate the role for long intergenic noncoding RNAs as scaffolds to regulate histone modification complexes and gene expression. more
total:14
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-TBP antibody was used to perform Chip or Web in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
total:3
Tumorigenic and metastatic activity of human thyroid cancer stem cells. 2010 to the paper
Novocastra anti-TTF1 antibody was used to perform immunohistochemistry in order to find out what activities of human thyroid cancer stem cells could be potential targets to treat thyroid carcinoma. more
total:4
Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere. 2007 to the paper
Santa Cruz Biotechnology monoclonal UBF1 antibody was used in western blot to study the role of centromere RNA during the assembly of nucleoproteins at the nucleolus and centromere more