Diseases associated with visual transduction
gene
reagent
sample publication
sample review
AKR1B10
aldo-keto reductase family 1 member B10
total:1
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. 2007 to the paper
Abgent Monoclonal anti-His antibody was used to perform immunoprecipitation in order to investigate the role of human Tim-Tipin complex during the UV-induced intra-S checkpoint.
apoA-I
apolipoprotein A1
total:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Abcam polyclonal rabbit anti-apoA-I antibody (1:10,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
APOA4
apolipoprotein A4
total:1
The expression of intact and mutant human apoAI/CIII/AIV/AV gene cluster in transgenic mice. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal human apoAIV antibody was used in western blot to study the expression of human apoAI/CIII/AIV/AV in transgenic mice
APOC2
apolipoprotein C2
total:2
Serum amyloid P colocalizes with apolipoproteins in human atheroma: functional implications. 2007 to the paper
Calbiochem rabbit polyclonal apoC-II antibody was used in immunohistochemistry to study the colocalization of serum amyloid P with apolipoproteins in human atheroma more
ApoE
apolipoprotein E
total:19
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Calbiochem anti-ApoE antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
apolipoprotein B
total:14
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Abcam anti-ApoB100 antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
CNGA1
cyclic nucleotide gated channel subunit alpha 1
CNGB1
cyclic nucleotide gated channel subunit beta 1
GNAT1
G protein subunit alpha transducin 1
GNB5
G protein subunit beta 5
total:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 to the paper
Dr. W. Simonds (NINDK) rabbit anti-VAChT antibody was used in western blot to study the localization and differential interaction of R7 RGS proteins with R7BP and R9AP in neurons of vertebrate retina.
GPC3
glypican 3
total:1
Differential expression of syndecans and glypicans in chronically inflamed synovium. 2008 to the paper
Santa Cruz Biotechnologies anti-glypican-3 antibody was used in immunohistochemistry to investigate which HSPGs are expressed in knee joint synovia from patients with different forms of arthritis and normal individuals.
GRK1
G protein-coupled receptor kinase 1
total:5
Arrestin competition influences the kinetics and variability of the single-photon responses of mammalian rod photoreceptors. 2009 to the paper
Affinity BioReagent monoclonal anti-rhodopsin kinase 1a antibody (1:1,000, MA1-720) was used in western blot to investigate the role of arrestin in mammalian rod's single-photon responses more
GUCA1A
guanylate cyclase activator 1A
total:1
Prolonged illumination up-regulates arrestin and two guanylate cyclase activating proteins: a novel mechanism for light adaptation. 2009 to the paper
Affinity BioReagents mouse anti-GCAP1 antibody was used in western blot in order to investigate the mechanism for light adaptation-associated changes in gene expression caused by prolonged illumination.
LDLR
low density lipoprotein receptor
total:10
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 to the paper
Santa Cruz anti-LDLr antibody was used in western blot in order to show that Wnt/catenin signaling, osteoblast function, and bone formation can be negatively regulated by the N-cadherin-axin-LRP5 interaction. more
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D
NMT1
N-myristoyltransferase 1
total:1
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 to the paper
BD Transduction Laboratories anti-NMT1 antibody was used in western blot to detect NMT1 in SK-OV-3 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.
NMT2
N-myristoyltransferase 2
total:1
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 to the paper
BD Transduction Laboratories anti-NMT2 antibody was used in western blot to detect NMT2 in SK-OV-3 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.
OPN1LW
opsin 1, long wave sensitive
total:2
Human cone photoreceptor dependence on RPE65 isomerase. 2007 to the paper
Santa Cruz Biotechnology polyclonal anti-human red/green opsin (sc-22117, 1:100) was used in immunohistochemistry to study human cone photoreceptor dependence on RPE65 isomerase more
OPN1SW
opsin 1, short wave sensitive
total:2
Human cone photoreceptor dependence on RPE65 isomerase. 2007 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human blue opsin (sc-14363, 1:50) was used in immunohistochemistry to study human cone photoreceptor dependence on RPE65 isomerase more
PDE6A
phosphodiesterase 6A
total:3
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
Abcam anti-PDE6A antibody(1:200 dilution)was used to perform immunohistochemistry in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
PDE6B
phosphodiesterase 6B
total:2
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
FabGennix anti-PDE6B antibody was used to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
PDE6G
phosphodiesterase 6G
total:2
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
Santa Cruz Biotechnology anti-PDE6G antibody was used to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
perlecan
heparan sulfate proteoglycan 2
total:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 to the paper
Chemicon monoclonal anti-perlecan antibody (MAB 1948) was used in frozen sections from mouse and in immunohistochemistry to study the identification of WARP as a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. more
PKC alpha
protein kinase C alpha
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
PPEF1
protein phosphatase with EF-hand domain 1
PRKCQ
protein kinase C theta
total:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKCtheta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
RBP1
retinol binding protein 1
total:4
Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation. 2008 to the paper
Santa Cruz aiti-CRBP-1 antibody was used to perform western blot in order to show that differential TGF-beta signaling can activate the stellate cells after liver injury. more
RDH11
retinol dehydrogenase 11
total:1
Apolipoprotein c1 association with hepatitis C virus. 2008 to the paper
Anogen mouse monoclonal anti-HCV core protein antibody (MO-I40015B) was used in immunocytochemistry to study the association of apolipoprotein C1 with hepatitis C virus.
recoverin
total:1
ATM localization and gene expression in the adult mouse eye. 2009 to the paper
Santa Cruz Biotechnology goat polyclonal anti-recoverin antibody was used in immunohistochemistry to incubate with the sections in order to determine the ATM expression patterns and studied its localization.
RGS9
regulator of G protein signaling 9
total:2
Differential expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age rats. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal anti-RGS9 antibody (1:100) was used in immunohistochemistry to study the different expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age rats. more
RGS9BP
regulator of G protein signaling 9 binding protein
rhodopsin
total:12
Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. 2009 to the paper
Abcam mouse anti-rhodopsin antibody was used for western blot in order to investigate the roles of Cep70 and Cep131 in the regulation of ciliogenesis in zebrafish embryos. more
SAG
S-antigen visual arrestin
total:4
Arrestin competition influences the kinetics and variability of the single-photon responses of mammalian rod photoreceptors. 2009 to the paper
Affinity BioReagent arrestin antibody was used in western blot to investigate the role of arrestin in mammalian rod's single-photon responses more
SDC2
syndecan 2
total:2
Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells. 2005 to the paper
Seikagaku HSPG neo-epitope (exposed after heparitinase III digestion, clone 3G10) antibody was used in western blot to study thrombin-induced human vascular smooth muscle cell migration and proliferation more
SDC3
syndecan 3
total:1
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue. 2006 to the paper
Zymed Laboratories rabbit anti syndecan-3 antibody was used in immunohistochemistry to study its expression in human uterine tissue during prolonged labour
SDC4
syndecan 4
total:3
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans. 2008 to the paper
Santa Cruz Biotechnology anti-syndecan-4 antibody was used in immunocytochemistry to study the effect of heparanase on cell adhesion and spreading. more
SDR9C7
short chain dehydrogenase/reductase family 9C member 7
STRA6
signaling receptor and transporter of retinol STRA6
syndecan
syndecan 1
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more
transthyretin
total:4
Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of keratoepithelin. 2005 to the paper
Dako polyclonal anti-transthyretin antibody was used in immunohistochemistry to study the association of hereditary lattice corneal dystrophy with corneal amyloid deposits enclosing C-terminal fragments of feratoepithelin. more