Disease
gene
reagent
sample publication
sample review
total:9
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3beta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
- 6 phosphofructo 2 kinase fructose 2 6 bisphosphatase antibody
- 6 phosphofructo 2 kinase fructose 2 6 bisphosphatase gene knockdown
- 6 phosphofructo 2 kinase fructose 2 6 bisphosphatase cDNA
- 6 phosphofructo 2 kinase fructose 2 6 bisphosphatase protein
- 6 phosphofructo 2 kinase fructose 2 6 bisphosphatase ELISA/assay
- 6 phosphofructo 2 kinase fructose 2 6 bisphosphatase other
total:2
Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases. 2009 to the paper
Novus Biologicals mouse anti-PFKFB3 (number H00005209-A01 and H00005209-M08) polyclonal and monoclonal antibodies were used to perform western blot in order to demonstrate that overexpression of 6-phosphofructo-2-kinase (PFKFB3) in the nuclear increases cell proliferation via cyclin-dependent kinases. more
total:17
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-ACC1 S79ph antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:1
Increased tartrate-resistant acid phosphatase (TRAP) expression in malignant breast, ovarian and melanoma tissue: an investigational study. 2006 to the paper
Novocastra Laboratories Ltd. TRAP monoclonal antibody against against the N-terminal portion of human TRAP (clone: 26E5, subtype: IgG2b) was used in immunocytochemistry and immunohistochemistry to study the TRAP expression in various malignant and benign breast, ovarian, and melanoma tissues.
total:10
S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10. 2009 to the paper
Chemicon ADAM-10 antibody was used for western blot in order to indentify new biomarker of Alzheimer's disease. more
total:4
The disintegrin and metalloproteinase ADAM12 contributes to TGF-beta signaling through interaction with the type II receptor. 2007 to the paper
Nathalie Th ret (Institut National de la Sant et de la Recherche Medicale) anti-ADAM12 Rb 122 was used in western blot and immunoprecipitation to study the role of disintegrin and metalloproteinase ADAM12 in TGF-beta signaling through interaction with the type II receptor more
total:13
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. 2008 to the paper
Santa Cruz Biotechnology anti-TACE antibody was used to perform Western Blot in order to show that TACE has a inhibitory role in EGFR axis in colorectal cancer. more
total:2
Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. 2005 to the paper
FabGennix isoform-specific anti-adenylate cyclase antibody was used in western blot to study the effedt of interferon-gamma on adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia. more
total:2
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. 2007 to the paper
Santa Cruz Biotechnology AC2 antibody was used in western blot to demonstrate stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. more
total:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Santa Cruz anti-adenylyl cyclase III antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
total:3
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 to the paper
Santa Cruz Biotechnology anti-adenylate cyclase antibody was used in western blot to study the role of PDE3B and its interaction with PKB for regulation of specific cAMP pools and signalling pathways by insulin. more
total:4
Expression of ZIC family genes in meningiomas and other brain tumors. 2010 to the paper
Sigma anti-chondroitin sulfate proteoglycan antibody was used to perform immunohistochemistry in order to study the expression of the ZIC family genes in different type of brain tumors. more
total:4
Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA. 2010 to the paper
Millipore anti-Ago2 antibody was used to carry out immunoprecipitation assays in order to investigate the role for Herpesvirus saimiri Noncoding RNA HSURs in the regulation of host cell microRNAs. more
total:1
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. 2007 to the paper
Abgent Monoclonal anti-His antibody was used to perform immunoprecipitation in order to investigate the role of human Tim-Tipin complex during the UV-induced intra-S checkpoint.
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:4
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. 2011 to the paper
Cell Signaling Technology anti-phospho-PRAS40 was used to perform western blot in order to show that how growth factor signaling is inhibited by mTOR through mTOR-regulated phosphoproteome. more
total:4
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. 2008 to the paper
Millipore anti-Akt3 was used to perform western blot in order to show that PTEN-null tumors is promoted to autophagy and more sensitive to lysosomotropic agents after Akt inhibition. more
total:1
Intrathecal administration of AAV vectors for the treatment of lysosomal storage in the brains of MPS I mice. 2006 to the paper
BioMarin Pharmaceutical rabbit polyclonal IDUA antibody was used in immunohistochemistry (1:3000) to determine the expression level of IDUA in the brain after AAV vectors.
total:33
Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells. 2008 to the paper
Santa Cruz Biotechnology anti-alpha-syn mAb211 antibody was used to perform western blot in order to develop a cell modle of LB-associated neurodegeneration. more
total:17
FCHo proteins are nucleators of clathrin-mediated endocytosis. 2010 to the paper
Transduction Laboratories mouse monoclonal anti-AP2A1 antibody was used to carry out western blot analysis in order to investigate the roles for FCHo1 and FCHo2 proteins in clathrin-mediated endocytosis in cell plasma membrane. more
total:3
GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. 2009 to the paper
Neomarkers rabbit anti-alpha-amylase antibody was used to carry out immunofluorescence assays in order to investigate the regulation of Gli1 transcription and its role in pancreatic ductal adenocarcinoma cell survival and transforming phenotype. more
total:3
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1g antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
V. Faundez anti-sigma3-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
total:5
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
Sigma anti-alpha-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. more
total:5
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1/2b antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
total:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 to the paper
BD Biosciences monoclonal anti-AP50 antibody was used in human HeLa cells or HUVECs and in western blot to study the role for clathrin adaptor AP2 in regulating thrombin receptor constitutive internalization and endothelial cell resensitization. more
total:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Abcam polyclonal rabbit anti-apoA-I antibody (1:10,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
total:1
The expression of intact and mutant human apoAI/CIII/AIV/AV gene cluster in transgenic mice. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal human apoAIV antibody was used in western blot to study the expression of human apoAI/CIII/AIV/AV in transgenic mice
total:2
Mutations in C2orf37, encoding a nucleolar protein, cause hypogonadism, alopecia, diabetes mellitus, mental retardation, and extrapyramidal syndrome. 2008 to the paper
Abgent rabbit polyclonal anti-C2orf37 antibody was used to perform immunohistochemistry in order to study the C2orf37 Mutations mediated Woodhouse-Sakati syndrome. more
total:2
Serum amyloid P colocalizes with apolipoproteins in human atheroma: functional implications. 2007 to the paper
Calbiochem rabbit polyclonal apoC-II antibody was used in immunohistochemistry to study the colocalization of serum amyloid P with apolipoproteins in human atheroma more
total:19
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Calbiochem anti-ApoE antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:14
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Abcam anti-ApoB100 antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:81
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Chemicon anti-APP was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:8
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 to the paper
Affinity Bioreagents anti-Arf antibody was used to perform western blot in order to study the interaction between Arf and Poliovirus Protein 3CD and its effect on poliovirus replication. more
total:1
GM130-dependent control of Cdc42 activity at the Golgi regulates centrosome organization. 2009 to the paper
Santa Cruz Biotechnology anti-beta-PIX antibody was used in western blot to study the role for GM130-dependent control of Cdc42 activity at the golgi in regulating centrosome organization
total:7
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
Santa Cruz Biotechnology beta-arrestin1/2 rabbit polyclonal antibody (21-B1) was used to perform western blot in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS. more
total:3
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. 2006 to the paper
Affinity BioReagents polyclonal anti-beta arrestin 2 antibody was used in human embryonic kidney (HEK) 293 cells and in western blot to study the role of G protein-coupled receptor kinase site serine cluster in beta-arrestin-dependent beta2AR internalization and desensitization. more
total:1
Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization. 2010 to the paper
BioVision rabbit anti-A1 polyclonal antibody (1/400) was used to perform western blot and immunoprecipitation in order to study the function of cancer cell lines mitochondria in exploring the mechanisms of BH3 peptides and ABT-737 induced mitochondrial membrane permeabilization.
total:1
Regulation of Spo12 phosphorylation and its essential role in the FEAR network. 2009 to the paper
Molecular Probes mouse anti-Vph1 antibody (1:2000 dilution) was used to perform western blot in order to investigate the regulation of S118 phosphorylation of Spo12 and its essential role for FEAR network function.
total:1
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Abcam anti-ATP6V0D1 was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation.
total:1
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
GeneTex anti-ATP6V1A was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation.
total:1
Topology of the yeast fatty acid transport protein Fat1p: mechanistic implications for functional domains on the cytosolic surface of the plasma membrane. 2007 to the paper
Molecular Probes mouse anti-Vma2p antibody was used in western blot to define the role of Fat1p in the transport of exogenous fatty acids.
total:1
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Santa Cruz anti-ATP6V1D was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation.
total:1
Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney. 2007 to the paper
Santa Cruz Biotechnology anti-human vacuolar type H+-ATPase B1/2 (V-ATPase) antibody was used in immunohistochemistry to localize broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney
total:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:5
Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression. 2008 to the paper
Dako anti-B2m was used to perform immunohistochemistry in order to study the presence of specific populations of tumor infiltrating lymphocytes in diagnostic primary melanoma biopsies are associated with outcome in clinically stage II melanoma patients. more
total:1
Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease. 2010 to the paper
Abnova anti-B3GALT6(M06) mouse monoclonal antibody was used to perform western blot in order to study the efficiency of using the small interfering RNA(siRNA) to control expression of particular genes involved in GAG synthesis for the treatment of mucopolysaccharidosis type III.
total:1
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
Invitrogen anti-Core1 antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA.
total:1
Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease. 2010 to the paper
Proteintech Group anti-B4GALT7 rabbit polyclonal antibody was used to perform western blot in order to study the efficiency of using the small interfering RNA(siRNA) to control expression of particular genes involved in GAG synthesis for the treatment of mucopolysaccharidosis type III.
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Cell Signaling Technology, anti-BAD monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:1
Binding of barrier to autointegration factor (BAF) to histone H3 and selected linker histones including H1.1. 2005 to the paper
Dr Roc o Montes de Oca anti-BAF antibody was used in immynoprecipitation to study the role of binding of barrier to autointegration factor (BAF) and selected linker histones.
total:7
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 to the paper
Cell Signaling Technology anti-pY-BCR-ABL antibody was used to carry out western blot analysis in order to investigate the mechanism for Lyn kinase regulating imatinib sensitivity in chronic myelogenous leukemia cells. more
total:2
ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx. 2005 to the paper
R&D Systems goat anti-human BTC ectodomain (Asp32 Tyr111) antibody was used in immunoprecipitation, biotinylated goat anti-human BTC ectodomain in western blot and mouse anti-human BTC ectodomain antibody in ELISA to study the role for ADAM10 to mediate ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate (APMA) and extracellular calcium influx. more
total:1
Differential profiling of breast cancer plasma proteome by isotope-coded affinity tagging method reveals biotinidase as a breast cancer biomarker. 2010 to the paper
GeneTex anti-BTB antibody was used to perform western blot in order to reveal that biotinidase was a breast cancer biomarker by isotope-coded affinity tagging method.
total:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Zymed Laboratories mouse anti-beta TRCP antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
total:42
Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. 2012 to the paper
NeoMarkers mouse anti-human CD117 monoclonal antibody was used to perform immunohistochemistry in order to analyze the cellular origin of adult functional blood vessels. more
total:235
Regulation of early adipose commitment by Zfp521. 2012 to the paper
Santa Cruz Biotechnology anti-MYC antibody was used to carry out western blot and immunoprecipitation assays in order to investigate the regulatory role of Zfp521 in determining the switch between the adipogenic and osteogenic lineages. more
total:6
Role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma: report of six cases and review of the literature. 2007 to the paper
Dako calcitonin antibody (1:200) was used in immunohistochemistry to study the role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma. more
total:3
Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation. 2005 to the paper
Transduction Laboratories monoclonal anti-CaMKIV antibody was used in western blot and immunocytochemistry to study the presence of CaMKIV in mammalian sperm and its role in the regulation of human sperm motility. more
total:75
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-caspase-9 antibody was used to perform immunocytochemistry in order to study the protective autophagy involved in trail resistance of apoptosis-defective tumor cells. more
total:13
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 to the paper
Cell Signaling Technology anti-pY774-c-Cbl antibody was used to carry out western blot analysis in order to investigate the mechanism for Lyn kinase regulating imatinib sensitivity in chronic myelogenous leukemia cells. more
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
total:3
Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. 2005 to the paper
Santa Cruz Biotechnology cyclin H antibody was used in western blot to study the role of Dmp1 in Ras-Raf-Arf signaling. more
total:5
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. 2008 to the paper
Santa Cruz anti-cyclin T1 antibody was used to perform western blot in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters. more
total:28
Effects of ferumoxides-protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells. 2008 to the paper
Biolegend FITC conjugated mouse anti-human CD195 IgG2a was used in flow cytometry in order to demonstrate that endocytosed FePro nanoparticles did not significantly affect immunological properties of THP-1 cells more
total:62
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Becton Dickinson anti-CD19 PE was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
total:68
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD3 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
total:25
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD28 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
total:118
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Beckman coulter anti-CD4 PC5 was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
total:49
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Millipore rat anti-heparan sulfate proteoglycan monoclonal antibody was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models. more
total:9
Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival. 2008 to the paper
Becton Dickinson anti-CD57 antibody was used in immunohistochemistry to investigate the relationship between IDO expression and tumor-infiltrating lymphocytes in endometrial cancer. more
total:24
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Beckman anti-CD80 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Beckman anti-CD86 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:5
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Becton Dickinson anti-CD8b antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk1 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:5
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import. 2007 to the paper
Affinity BioReagents anti-Cdc37 antibody was used in western blot in order to investigate the functions of Hsp40-related J-domain proteins DJA1, DJA2, and DJA4 during mitochondrial import. more
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK7 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:5
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK8 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:11
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK9 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:1
Cyclin K and cyclin D1b are oncogenic in myeloma cells. 2010 to the paper
Santa Cruz anti-p15 was used to perform western blot in order to show the role of cyclin K and cyclin D1b in multiple myeloma.
total:11
In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis. 2009 to the paper
Abcam rabbit anti-CHIP was used to perform western blot in order to show that enhancing CHIP activity is good for therapy for SCA3 or other polyQ diseases more
total:1
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. 2011 to the paper
Abcam antibody mouse rabbit anti-CHMP2B antibody was used to perform immunohistochemistry in order to study quantification of CHMP2B on intercellular bridges at different stages.
total:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 to the paper
Bethyl Laboratory Inc. rabbit anti-Vps24 antibody was used in western blot to study the interaction of the mammalian endosomal sorting complex required for rransport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-CHMP4A was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-CHMP4B was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:2
Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase. 2005 to the paper
ICN Biomedicals 20-HSD antiserum (1:1000) was used in western blot to determine the relative contribution of 20alpha-HSD to progesterone metabolism and Stat5 function during pregnancy and parturition. more
total:5
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Sigma-Aldrich monoclonal anti-clathrin light chain antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
total:58
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:1
Comparison between human fetal and adult skin. 2010 to the paper
Sigma anti-chondroitin sulfate was used to perform immunohistochemistry in dilution 1:500 in order to show that dermal components express differentially between human fetal and adult skin and play important roles in fetal scarless healing.
total:7
Leukocyte-associated Ig-like receptor-1 has SH2 domain-containing phosphatase-independent function and recruits C-terminal Src kinase. 2006 to the paper
Santa Cruz anti-Csk antibody was used in immnoprecipitation to study the role of leukocyte-associated Ig-like receptor-1. more
total:1
Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes. 2005 to the paper
Alpha Diagnostic International rabbit anti-human C-terminal modulator protein (CTMP) antibody was used in western blot to study the effect of the interaction between histone deacetylase inhibitors and protein phosphatase 1 complexes on Akt in human U87MG cells.
total:12
Mediator acts upstream of the transcriptional activator Gal4. 2012 to the paper
Abcam anti-Cul1 mouse monoclonal antibody was used to perform immunoprecipitation in order to study how the Mediator initiated Gal4 transcription. more
total:3
Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse. 2009 to the paper
Santa Cruz Biotechnology Cux-1 antibody was used in immunohistochemistry in order to demonstrate that the brain tuberous sclerosis complex (TSC) can be caused by the loss of function of Tsc2 in radial glia. more
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:2
Cytochrome b5 expression in gonadectomy-induced adrenocortical neoplasms of the domestic ferret (Mustela putorius furo). 2008 to the paper
Santa Cruz Biotechnology rabbit anti-human cyt b5 antibody was used in immunohistochemistry at 1:200 dilution in order to demonstrate that that cyt b5 is upregulated during gonadectomy-induced adrenocortical neoplasia and is a marker of androgen synthetic potential in these tumors more
total:4
The association of vascular endothelial growth factor receptor-1 with the risk of cancer progression following radical prostatectomy. 2008 to the paper
Novus Biologicals mouse anti-p22phox monoclonal antibody was used to perform Western blotting assays in order to study the molecular mechanisms of C-reactive protein in inhibiting cholesterol efflux from human foam cells. more
total:7
IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase. 2009 to the paper
BD Transduction monoclonal anti-Nox2 antibody was used in immunohistochemistry in order to study the role of IL-6 in degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice. more
total:9
Hepatitis B virus (HBV) surface antigen interacts with and promotes cyclophilin a secretion: possible link to pathogenesis of HBV infection. 2010 to the paper
Proteintech anti-CypA monoclonal antibody was used to perform western blot in order to study the role of HBV small surface protein(SHBs) in promoting the pathogenesis of HBV infection. more
total:1
Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment. 2005 to the paper
Research Genetics/Invitrogen rabbit anti-human DHFR polyclonal antibody was used in western blot to study the essential of identification of amino acids for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate treatment.
total:2
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors. 2005 to the paper
Santa Cruz Biotechnology polyclonal anti-Delta1 antibody (sc-8155) was used in immunohistochemistry to study the effect of Delta1 versus Jagged1 on T-cell progenitors at specific developmental stages in sections from human thymic tissue. more
total:1
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. 2007 to the paper
I. B. Lobov (Regeneron Pharmaceuticals) Dll4 antibody was used in immunohistochemistry to study the role of Dll4 during vascular growth and differentiation.
total:4
The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo. 2009 to the paper
Abcam DNA ligase IV antibody was used for western blot in order to investigate the role of the c-terminal domain of cernunnos/XLF in the regulation of DNA repair in vivo. more
total:11
Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor. 2007 to the paper
Santa Cruz anti-E2F4 was used to perform ChIP assays in order to show that the evolutionarily conserved gene targets of E2F4 play important roles for cell cycle. more
total:9
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-EGF antibody was used in immunohistochemistry to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms. more
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:4
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-N-terminus enolase antibody was used to carry out western blot analysis in order to clarify an alternative glycolytic pathway in many rapidly proliferating cells. more
total:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 to the paper
Upstate Laboratories anti-eNOS antibody was used for western blot in order to investigate the role of purinergic in the regulation of endothelial nitric oxide synthase activity in endothelial cells. more
total:2
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 to the paper
Epitomics anti-Epsin1 antibody was used to perform western blot in order to study the roles of the lipid raft-dependent Fc secre tRI ubiquitination in the regulation of receptor endocytosis. more
total:3
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 to the paper
Santa Cruz anti-Eps15 antibody was used to perform western blot in order to study the roles of the lipid raft-dependent Fc secre tRI ubiquitination in the regulation of receptor endocytosis. more
total:2
A requirement for epsin in mitotic membrane and spindle organization. 2009 to the paper
Epitomics rabbit monoclonal anti-Eps15R antibody was used for western blot in order to show that epsin is essential to regulate mitotic membrane morphology and spindle integrity. more
total:18
Activation of Stat3 by heregulin/ErbB-2 through the co-option of progesterone receptor signaling drives breast cancer growth. 2009 to the paper
Neomarkers ErbB-3 mouse monoclonal antibody was used to carry out antibody blocking assays in order to investigate the signal cross talk between ErbB2 and PR receptor and the effect on breast cancer growth. more
total:20
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 2009 to the paper
Santa Cruz Biotechnology anti-ERBB4 antibody was used in immunoprecipitation and western blot in order to characterize the role of ERBB4 mutations in melanoma. more
total:3
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-XPD was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:5
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-XPB was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:1
Human corneal epithelial cell proliferation by epiregulin and its cross-induction by other EGF family members. 2007 to the paper
R & D Systems anti-epiregulin antibody was used in immunohistochemistry to study human corneal epithelial cell proliferation by epiregulin and its cross-induction by other EGF family members
total:252
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Millipore anti-ERK1/2 polyclonal antibody (1:10,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediated anti-apoptotic effects. more
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:6
Fatty acid synthase expression in cutaneous melanocytic neoplasms. 2005 to the paper
Immuno-Biological Laboratories anti-fatty acid synthase antibody was used in immunohistochemistry to study expression of fatty acid synthase in cutaneous melanocytic neoplasms. more
total:1
Cell-cell contact globally activates microRNA biogenesis. 2009 to the paper
Upstate anti-Ago antibody was used to perform western blot in order to study the association between the cell-cell contact and microRNA biogenesis.
total:4
The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. 2013 to the paper
Abcam RNA polymerase II CTD repeat YSPTSPS peptide-phospho S2 antibody was used to perform western blot in order to study the structure and function of the tripartite complex containing P-TEFb,AFF4HIV and HIV Tat. more
total:20
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 to the paper
Chemicon rabbit polyclonal anti-FGF2 antibody was used in western blot to study the role for endothelial-derived FGF2 in the progression of pulmonary hypertension in humans and rodents. more
total:2
HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. 2006 to the paper
R&D Systems goat polyclonal anti-human FGF-1 antibody was used in ELISA to study the HSulf-2 which selectively mobilizes heparin-bound growth factors and chemokines. more
total:2
Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. 2008 to the paper
R&D Systems FGF9 antibody was used in immunohistochemistry at 5 ug/ml in order to study the role of androgen receptor null cells in prostate cancer bone metastases treatment more
total:17
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Biosource International anti-FGFR-1 (pYpY653/654) antibodies were used to perform western blot and ELISA analyses in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:9
Endothelial function of von Hippel-Lindau tumor suppressor gene: control of fibroblast growth factor receptor signaling. 2008 to the paper
Santa Cruz rabbit polyclonal anti-FGFR2 was used to perform western blot in order to show that VHL tumor supppressor gene has endothelial function through fibroblast growth factor receptor signaling. more
total:7
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Santa Cruz mouse anti-FGFR3 was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:5
Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-FGFR4 antibody was used to carry out western blot analysis in order to investigate whether FGFR4 plays a role in promoting the progression of hepatocellular carcinoma. more
total:4
Biomarkers for ragwort poisoning in horses: identification of protein targets. 2008 to the paper
Affiland rabbit (polyclonal) anti-(equine) fibrinogen antibody was used in western blot in order to investigate whether pyrrole toxins induce specific modifications of equine blood proteins that are detectable by proteomic methods more
total:8
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response. 2011 to the paper
Affinity Bioreagents anti-FKBP12 was used to perform western blot in order to show that unfolded protein response is induced by Ire1-unfolded protein interaction. more
total:20
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-FKHR antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more
total:18
CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16.. 2013 to the paper
Cell Signaling rabbit anti-mFOXO3(phospho-S252)/hFOXO3(phospho-S253) antibody was used to perform western blot in order to investigate the regulatory effect of calcineurin and CAMKII on the lifespan of Caenorhabditis elegans. more
total:1
Daughter centriole elongation is controlled by proteolysis. 2010 to the paper
Proteintech Group rabbit anti-human FGFR1OP antibody was used to perform immunocytochemistry in order to study the role of proteolysis in daughter centriole elongation.
total:4
Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. 2008 to the paper
Chemicon monoclonal mouse anti-O4 antibody (clone:81, Cat:MAB345) was used in immunohistochemistry to study what happens in the cerebellar cortex of peripuberal rabbits by using endogenous and exogenously-administered cell proliferation antigens in association with a cohort of typical markers for neurogenesis. more
total:6
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Santa Cruz rabbit anti-FRS was used at 1:250 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-FYN antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking. more
total:9
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Upstate Biotechnology polyclonal anti-Gab1 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
total:6
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Upstate anti-Gab2 polyclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
total:5
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
ProteinTech Group anti-PPP1R15A/GADD34 was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
total:15
Adaptor heat shock protein complex formation regulates trafficking of the asialoglycoprotein receptor. 2006 to the paper
Sigma mouse monoclonal anti-gamma-subunit of AP1 antibody was used in western blot to study the effect of adaptor heat shock protein complex formation on trafficking of the asialoglycoprotein receptor in HuH-7 and Trf1 human hepatoma cell lines. more
total:8
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Sigma anti-gelsolin antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
total:4
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-gephyrin antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
total:7
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. 2010 to the paper
Invitrogene anti-beta-Galactosidase antibody was used in immunocytochemistry for immunofluorescent staining to investigate the role of the NMDA receptors in the regulation of nicotine-conditioned place preference in dopamine neurons. more
total:1
Spermatogenic cell-specific type 1 hexokinase is the predominant hexokinase in sperm. 2008 to the paper
ABGENT anti-GCK(N-term) polyclonal antibody was used to perform immunoblotting in order to study the role of spermatogenic cell-specific type 1 hexokinase(HK1S) in sperm.
total:7
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
Novus Biologicals anti-G6PD antibody was used to perform western blot in order to study the function of quiescent fibroblasts. more
total:1
Decreased expression of human D-glucuronyl C5-epimerase in breast cancer. 2008 to the paper
GenScript Corporation anti-GLCE antibody was used to perform western blot in order to study the GLCE expression in human breast cancer.
total:23
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. 2009 to the paper
Abcam rabbit polyclonal anti-GLUT1 antibody was used to perform immunoblot in order to study the roles of the glucose deprivation during the development of KRAS pathway mutation. more
total:11
ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. 2009 to the paper
Millipore anti-Glut4 antibody was used to carry out western blot analysis in order to investigate the regulation of adipocyte glucose transport by ClipR-59 mediated Akt cellular compartmentalization. more
total:2
Increased MCP-1 and microglia in various regions of the human alcoholic brain. 2008 to the paper
IBL anti-GluT5 antibody (1:400) was used to perform immunohistochemistry in order to study the MCP-1 expression and microglia activities in alcoholic brains. more
- glyceraldehyde 3 phosphate dehydrogenase antibody
- glyceraldehyde 3 phosphate dehydrogenase gene knockdown
- glyceraldehyde 3 phosphate dehydrogenase cDNA
- glyceraldehyde 3 phosphate dehydrogenase protein
- glyceraldehyde 3 phosphate dehydrogenase inhibitor/activator/substrate/reporter
- glyceraldehyde 3 phosphate dehydrogenase ELISA/assay
- glyceraldehyde 3 phosphate dehydrogenase other
total:84
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Abcam anti-GAPDH antibody was used to perform western blot in order to study synaptic plasticity more
total:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 to the paper
Dr. W. Simonds (NINDK) rabbit anti-VAChT antibody was used in western blot to study the localization and differential interaction of R7 RGS proteins with R7BP and R9AP in neurons of vertebrate retina.
total:1
Differential expression of syndecans and glypicans in chronically inflamed synovium. 2008 to the paper
Santa Cruz Biotechnologies anti-glypican-3 antibody was used in immunohistochemistry to investigate which HSPGs are expressed in knee joint synovia from patients with different forms of arthritis and normal individuals.
total:36
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal against Ron antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer. more
total:5
Arrestin competition influences the kinetics and variability of the single-photon responses of mammalian rod photoreceptors. 2009 to the paper
Affinity BioReagent monoclonal anti-rhodopsin kinase 1a antibody (1:1,000, MA1-720) was used in western blot to investigate the role of arrestin in mammalian rod's single-photon responses more
total:9
Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2. 2008 to the paper
Santa Cruz Biotechnolog GRK2 polyclonal antibody was used to immunodetect myocardial levels in order to study the uncoupling of myocardial beta-Adrenergic receptor signaling during coronary artery bypass grafting: The Role of GRK2 more
total:23
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 alpha antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:79
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 beta antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:1
Human La is found at RNA polymerase III-transcribed genes in vivo. 2005 to the paper
Santa Cruz Biotechnology TFIIA antibody was used in ChIP assay to study the association of human autoantigen La with pol III-transcribed genes in vivo
total:2
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 to the paper
Santa Cruz TFIIEa antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires. more
total:3
Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin. 2009 to the paper
Santa Cruz anti-TFIIF antibody was used to perform ChIP assays in order to study the association between the papillomavirus E2 proteins, the host Brd4 protein and the transcriptionally active cellular genes. more
total:1
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. 2009 to the paper
Santa Cruz Biotechnology TFIIH antibody was used in western blot to study the regulation of aromatase transcription and estrogen biosynthesis in adipose stromal cells (ASCs).
total:1
Prolonged illumination up-regulates arrestin and two guanylate cyclase activating proteins: a novel mechanism for light adaptation. 2009 to the paper
Affinity BioReagents mouse anti-GCAP1 antibody was used in western blot in order to investigate the mechanism for light adaptation-associated changes in gene expression caused by prolonged illumination.
total:3
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. 2009 to the paper
Santa Cruz goat anti-GW182 antibody (1:100) was used to perform immunofluorescence in order to prove that the association of AKAP350A and CCAR1 with RNA stress granules is microtubule dependent. more
total:1
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Biosource glycogen synthase phosphorylated on Ser 641 and 645 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:1
Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. 2007 to the paper
Dr. Peter Cheung (Ontario Cancer Institute) rabbit H2A.Z-specific antibodies (the H2A.Z-L1 antibody was raised against the peptide sequence KSSRTTSHGR, and the H2A.Z-C antibody was raised against the peptide sequence IPHIHKSLIGKKGQQKTV) was used in western blot and immunocytochemistry to study H2A.Z monoubiquitylation as the marker for its association with euchromatin or facultative heterochromatin
total:62
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Millipore Gamma-H2AX antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:32
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-H3K4 antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
total:5
Hsp90alpha recruited by Sp1 is important for transcription of 12(S)-lipoxygenase in A431 cells. 2005 to the paper
Upstate Biotechnology acetyl-H3 antibody was used in ChIP assay to study 12 (S) Lipoxygenase transcription in A431 cells more
total:11
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Active Motif anti-H4K12Ac antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:1
Intronic splicing of hyaluronan synthase 1 (HAS1): a biologically relevant indicator of poor outcome in multiple myeloma. 2005 to the paper
Washington Biotechnology rabbit polyclonal anti-HAS1 antibody was used in western blot to study the intronic splicing of hyaluronan synthase 1 (HAS1).
total:6
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
R&D Systems goat anti-HB-EGF polyclonal antibody was used in immunoprecipitation and immunohistochemistry (1:50) in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:9
Regulation of p73 by Hck through kinase-dependent and independent mechanisms. 2007 to the paper
Santa Cruz rabbit polyclonal anti-Hck was used to perform western blot and immunoprecipitation and immunocytochemistry in order to show the mechanisms through which Hck regulates p73 function more
total:54
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-HDAC1 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:2
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Abgent anti-HDAC10 antibody was used to perform western blot in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:1
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Abgent anti-HDAC10 antibody was used to perform western blot in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression.
total:24
High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo. 2009 to the paper
Abcam anti-HDAC2 antibody was used to perform immunohistochemistry in order to study the association between the high class I HDAC activity and RelA/p65 activation in pancreatic cancer. more
total:21
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 to the paper
Santa Cruz Biotechnology anti-HDAC3 antibody was used to perform western blot assay in order to identify novel histone deacetylase complexes that promote expansions of trinucleotide repeats. more
total:6
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Active Motif anti-HDAC4 antibody was used to perform ChIP assays in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:6
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 to the paper
Assay Biotech anti-phospho-HDAC5 (Ser498) antibody was used for western blot in order to investigate the role of CaMKII in the regulation of pressure overload-induced cardiac hypertrophy to heart failure in mice. more
total:9
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. 2010 to the paper
Santa Cruz rabbit anti-HDAC6 antibody (WB, 1:2000; IF, 1:500) was used to perform western blot and immunofluorescence in order to study knockdown of TDP-43 mediated HDAC6 downregulation. more
total:3
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Novus Biologicals anti-HDAC7 antibody was used to perform ChIP assays in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:3
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Santa Cruz Biotechnology anti-HDAC8 antibody was used to perform western blot in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:2
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Santa Cruz Biotechnology anti-HDAC9 antibody was used to perform western blot in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:6
Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. 2009 to the paper
Abgent anti-HPSE rabbit antibody (1:200) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules. more
total:69
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. 2008 to the paper
Zymed Laboratories anti-c-erbB-2 antibody was used in immunohistochemistry to investigate the relationship between amphiregulin expression and liver metastases of colorectal cancer. more
total:3
Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer. 2009 to the paper
Chemicon Hes1 antibody was used in western blot in order to generate monoclonal antibodies to evaluate therapeutic potential of targeting EphA2 in pancreatic tumor. more
total:1
Hey1, a mediator of notch signaling, is an androgen receptor corepressor. 2005 to the paper
Chemicon International rabbit anti-human Hey1 affinity-purified polyclonal antibody was used in western blot, immunoprecipitation, and immunohistochemistry to identify Hey1 as an androgen receptor corepressor.
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:1
Testis/sperm-specific histone 2B in the sperm of donors and subfertile patients: variability and relation to chromatin packaging. 2007 to the paper
Chemicon International TSH2B antibody was used in western blot to assesse the association of TSH2B with chromatin compaction status.
total:1
p53 chromatin epigenetic domain organization and p53 transcription. 2009 to the paper
Abcam anti-histone H2Bantibody was used to perform immunoprecipitation in order to demonstrate that physical barrier due to the folding of chromatin in domain II can give rise to the depletion of RNA polymerase II.
total:5
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Abcam anti-Histone 3, anti-H3 K9Me, and anti-H3 S10ph antibodies were used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:6
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Abcam anti-H2A antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:10
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-H2B antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:3
Spermatogenic cell-specific type 1 hexokinase is the predominant hexokinase in sperm. 2008 to the paper
Chemicon International anti-hexokinase type 1 polyclonal antibody was used to perform immunoblotting in order to study the role of spermatogenic cell-specific type 1 hexokinase(HK1S) in sperm. more
total:7
Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis. 2009 to the paper
Millipore HK2 antibody was used to perform western blot in order to investigate the relations between hexokinase 2 and prognosis of breast cancer more
total:1
Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis. 2009 to the paper
Abgent rabbit anti-Hexokinase 3 polyclonal antibody was used to perform western blot in order to investigate the relations between hexokinase 2 and prognosis of breast cancer
total:8
Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. 2008 to the paper
Santa Cruz Biotechnology anti-HLA-A(A-18) antibody was used to perform immunohistochemistry in order to study tumor and tumor-stromal cell interactions. more
total:3
HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells. 2009 to the paper
Santa Cruz anti-HMGA1 antibody was used to perform western blot in order to study the role of HMGA2 in maintaining the oncogenic RAS-induced epithelial-mesenchymal transition. more
total:1
Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. 2009 to the paper
Vector Laboratories primary anti-FLAG BioM2 antibody was used to do western blot analysis in order to study the preferential expression of the arylsulfatase I (ARSI) gene in retinal pigment epithelium cell line ARPE-19.
total:1
Heparanase expression in circulating lymphocytes of breast cancer patients depends on the presence of the primary tumor and/or systemic metastasis. 2007 to the paper
Santa Cruz Biotechnology HPA2 antibody was used in immunocytochemistry (1:100) to demonstrate that heparanase was expressed in lymphocytes of breast cancer PBMC.
total:68
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-HSP90 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:1
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
Lifespan Biosciences anti-IDH1 antibody was used to perform western blot in order to study the function of quiescent fibroblasts.
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:38
Hepatitis C virus targets over-expression of arginase I in hepatocarcinogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-iNOS antibody was used in western blot to study the role for elevated arginase expression in HCV associated HCC more
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:37
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. 2011 to the paper
Invitrogen anti-phospho-IRS (Y612) was used to perform western blot in order to show that Grb10 was indentified as a negative regulator of insulin signaling by phosphoproteomic analysis. more
total:13
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Upstate Irs2 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models more
- islet specific glucose 6 phosphatase catalytic subunit related protein antibody
- islet specific glucose 6 phosphatase catalytic subunit related protein gene knockdown
- islet specific glucose 6 phosphatase catalytic subunit related protein cDNA
- islet specific glucose 6 phosphatase catalytic subunit related protein protein
- islet specific glucose 6 phosphatase catalytic subunit related protein other
total:3
Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation. 2009 to the paper
BD Biosciences Itch monoclonal antibody was used to perform western blot and immunoprecipitation in order to demonstrate the key mechanisms that regulate p63 protein stability in vivo. more
total:1
The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production. 2005 to the paper
BMA chicken BRI2 IgY polyclonal antibody was used in western blot and immunoprecipitation to investigate the binding of BRI2 to APP precursor protein.
total:5
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 to the paper
Calbiochem IP3R1 antibody was used in western blot and immunohistochemistry to study the role of molecular alterations in the cerebellum of the PMCA2-null in Purkinje neurons. more
total:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 to the paper
Santa Cruz Biotechnology goat anti-IP3R2 antibody was used in western blot to study the binding of phospholipid scramblase 1 to the promoter region of the inositol 1, 4, 5-triphosphate receptor type 1 more
total:2
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
Santa Cruz Biotechnologies Biosystems anti-JAGGED2 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:12
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
R&D Systems anti-Jagged1 antibody was used to perform flow cytometry in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
total:9
MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA. 2010 to the paper
Santa Cruz Biotechnology anti-JunB antibody was used for western blot in order to investigate the roles of MDA5 and PTPN2 in the regulation of pancreatic cell responses to the viral by-product double-stranded RNA. more
total:2
A phosphorylation-acetylation switch regulates STAT1 signaling. 2009 to the paper
Santa Cruz Biotechnology GCN5 antibody was used for western blot in order to investigate the role of phosphorylation-acetylation switch in the regulation of STAT1 signaling. more
total:2
Ketohexokinase: expression and localization of the principal fructose-metabolizing enzyme. 2009 to the paper
Abgent rabbit purified polyclonal KHK (C-terminal) antibody was used to perform immunohistochemistry in order to investigate the functions of ketohexokinase. more
total:5
Vascular precursors in developing human retina. 2008 to the paper
Assay Designs anti-SCF antibody was used to perform immunohistochemistry in order to study vascular precursors of human retina. more
total:1
Novel nuclear import of Vpr promoted by importin alpha is crucial for human immunodeficiency virus type 1 replication in macrophages. 2007 to the paper
MBL monoclonal importin alpha 5/7 antibody was used in western blot to study novel nuclear import of Vpr promoted and its roles in human immunodeficiency virus type 1 replication in macrophages
total:7
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-importin beta antibody (sc-137016) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
total:19
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Abcam anti-Ku70 antibody was used to perform immunoblotting in order to studythe role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:22
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Life Technologies anti-Ku80 antibody was used to perform immunoprecipitation and immunofluorescence in order to study IRF-3-dependent innate immunity. more
total:1
Stimulatory cross-talk between NFAT3 and estrogen receptor in breast cancer cells. 2005 to the paper
Stratagene anti-Lac polyclonal antibody was used in western blot to identify the transcription factor NFAT3 as a new ER-interacting partner in breast cancer cells.
total:6
Mycobacterial disease and impaired IFN-? immunity in humans with inherited ISG15 deficiency. 2012 to the paper
Abcam anti-lactoferrin was used to perform immunocytochemistry in order to show that ISG15 deletion in humans impairs IFN-gamma immunity and results in mycobacterial disease susceptibility. more
total:18
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology Lck antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
total:10
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 to the paper
Santa Cruz anti-LDLr antibody was used in western blot in order to show that Wnt/catenin signaling, osteoblast function, and bone formation can be negatively regulated by the N-cadherin-axin-LRP5 interaction. more
total:8
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
HyCult Technologies anti-cathelicidin (3D11, 1:200) monoclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder. more
total:7
Human ?-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets. 2012 to the paper
Dako Cytomation anti-lysozyme was used at 1:1000 to perform western blot in order to show that mucosal innate immunity could be promoted by HD6 self-assembly. more
total:7
Altered regulation of Prox1-gene-expression in liver tumors. 2008 to the paper
Reliatech rabbit polyclonal anti-Lyve-1 (1:500) antibody was used in immunohistochemistry to study Prox1-gene-expression in liver tumors more
total:38
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. 2010 to the paper
Calbiochem anti-Hdm2 antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis. more
total:57
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Cell Signaling Technology anti-MEK1 antibody was used to perform flow cytometry and immunochemistry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:16
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. 2010 to the paper
Cell Signaling Technologies anti-phospho-MEK1/2 antibody was used to perform western blot in order to study the discrimination between the yeast and hyphal forms of C. albicans in epithelial cells via a biphasic MAPK response. more
total:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 to the paper
Bethyl Laboratories anti-menin antibody was used for coimmunoprecipitation in order to illustrate the role of c-Myb in MLL-associated leukemogenesis. more
total:2
MFG-E8 in the retina and retinal pigment epithelium of rat and mouse. 2006 to the paper
Invitrogen MFG-E8 antibody was used in western blot to investigate a potential role for MFG-E8 in the phagocytosis of photoreceptor outer segments (POS). more
total:1
Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells. 2005 to the paper
Cell Signaling anti-phospho-MNK1 (Thr197/202) antibody was used in human NK92 cells and in western blot to study the role for the interleukins 2 and 15 in regulating Ets1 expression in human natural killer cells.
total:2
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". 2006 to the paper
Santa Cruz monoclonal anti-Mat1 antibody (F-6) was used in human T98G cells and in western blot to study the role for cyclins and CDK "inhibitors" in Thr172 phosphorylation of CDK4. more
total:2
Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity. 2010 to the paper
Proteintech Group anti-Mov10 antibody was used to perform western blotting in order to study if overexpression of Mov10 in cells would inhibit HIV-1 infectivity. more
total:1
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 2009 to the paper
Abgent anti-MTMR4 antibody was used to perform western blot in order to study the role of Nedd4 plays in the biological process of muscle breakdown.
total:33
A gene signature-based approach identifies mTOR as a regulator of p73. 2008 to the paper
Santa Cruz polyclonal anti-mTOR (N-19 (alpha-FRAP) was used to perform western blot in order to show that mTOR is identified as a regulator of p73 by a gene signature-based approach. more
total:2
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Protein-Tech anti-CBP80 antibody was used in western blot in order to investigate the function of surveillance complex associated with ribosome during nonsense-mediated mRNA decay (NMD). more
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abgent CBP20 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:2
A3 adenosine receptor activation decreases mortality and renal and hepatic injury in murine septic peritonitis. 2006 to the paper
Serotec neutrophils antibody was used in immunohistochemistry to determine the effects of A3AR modulation on mortality and hepatic and renal dysfunction in a murine model of sepsis. more
total:14
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-p300 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:7
CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha. 2007 to the paper
Axxora Nedd8 antibody was used in western blot to demonstrate that CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha. more
total:12
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
Chemicon anti-NG2 antibody (1:1500) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation. more
total:10
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 to the paper
Calbiochem rabbit anti-nicastrin antibody was used to perform western blot in order to study the effect of TNF-alpha on gamma-secretase. more
total:1
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 to the paper
BD Transduction Laboratories anti-NMT1 antibody was used in western blot to detect NMT1 in SK-OV-3 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.
total:1
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 to the paper
BD Transduction Laboratories anti-NMT2 antibody was used in western blot to detect NMT2 in SK-OV-3 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.
total:8
Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor activation in primary neuronal cultures. 2009 to the paper
Zymed Laboratories anti-nNOS antibody was used for western blot in order to investigate the role of Estradiol in the regulation of nitric oxide formation in primary neuronal cultures. more
total:17
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. 2010 to the paper
Epitomics anti-Notch1 antibody was used to carry out western blot analysis in order to investigate the regulation of Notch signaling and cell differentiation by mTOR signaling. more
total:11
Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. 2010 to the paper
Zymed anti-NPM antibody was used for western blot in order to investigate the role for activated Bax in the regulation of p53-dependent, transcription-independent neural precursor cell apoptosis. more
total:4
Selectively oncolytic mutant of HSV-1 lyses HeLa cells mediated by Ras/RTN3. 2007 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-Ras antibody was used in western blot to study mechanism mtHSV was targeted for treating tumors but not other organs. more
total:3
Immortalization and characterization of lineage-restricted neuronal progenitor cells derived from the porcine olfactory bulb. 2008 to the paper
Abcam rabbit anti-neuregulin-1 antibody (1:100) was used in immunocytochemistry in order to study the role of CCR5 in the migration of pulmonary fibrocytes and the promotion of metastasis more
total:11
The diagnostic value of SYT-SSX detected by reverse transcriptase-polymerase chain reaction (RT-PCR) and fluorescence in situ hybridization (FISH) for synovial sarcoma: a review and prospective study of 255 cases. 2008 to the paper
Zymed Laboratory anti-NSE (G4) antibody was used to perform immunohistochemistry in order to study the diagnostic value of SYT-SSX detected by RT-PCR and FISH for synovial sarcoma. more
total:8
Fractionation of the Coxiella burnetii parasitophorous vacuole. 2008 to the paper
BD Biosciences mouse anti-human nuclear pore protein nucleoporin p62 antibody was used to perform western blot in order to develope a method to separate intact parasitophorous vacuole from host cell material. more
total:1
The nucleoporin Nup153 has separable roles in both early mitotic progression and the resolution of mitosis. 2009 to the paper
Covance anti-nucleoporin antibody was used to perform western blot in order to study the roles of Nup153 plays in mitosis.
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Abcam monoclonal anti-NUP was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:1
Caspases target only two architectural components within the core structure of the nuclear pore complex. 2006 to the paper
BD Biosciences monoclonal Nup88 antibody was used in western blot to identify caspase targets in the core structure of nuclear pore complex in Hela cells
total:10
Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. 2008 to the paper
R&D Systems monoclonal anti-Nur77 was used to perform immunocytochemistry in dilution 1:200 in order to show that acetylshikonin and analogues induce apoptosis through orphan nuclear receptor Nur77-mediated apoptotic pathway in cancer cells. more
total:2
Human cone photoreceptor dependence on RPE65 isomerase. 2007 to the paper
Santa Cruz Biotechnology polyclonal anti-human red/green opsin (sc-22117, 1:100) was used in immunohistochemistry to study human cone photoreceptor dependence on RPE65 isomerase more
total:2
Human cone photoreceptor dependence on RPE65 isomerase. 2007 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human blue opsin (sc-14363, 1:50) was used in immunohistochemistry to study human cone photoreceptor dependence on RPE65 isomerase more
total:8
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p107 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-p110alpha was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:178
Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 to the paper
Abcam mouse anti-p21 antibody was used to perform western blot in order to study the mechanism through which doxorubicin suppressed tumor growth. more
total:118
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 to the paper
BD Pharmingen anti-p27CDKN1B antibody was used to perform western blot in order to show that p53-dependent cell proliferation and survival could be regulated by atg7. more
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:10
The association of vascular endothelial growth factor receptor-1 with the risk of cancer progression following radical prostatectomy. 2008 to the paper
Novus Biologicals anti-p47-phox antibody was used to perform Western blotting assays in order to study the molecular mechanisms of C-reactive protein in inhibiting cholesterol efflux from human foam cells. more
total:8
The association of vascular endothelial growth factor receptor-1 with the risk of cancer progression following radical prostatectomy. 2008 to the paper
Novus Biologicals anti-p67-phox mouse polyclonal antibody(H00004688-B01)was used to perform Western blotting assays in order to study the molecular mechanisms of C-reactive protein in inhibiting cholesterol efflux from human foam cells. more
total:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Upstate anti-p85 pAb was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal regulator PA200 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
total:4
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Santa Cruz Biotechnology anti-CBP antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:16
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 to the paper
Novus Biologicals goat anti-human plasminogen antibody was used to perform ELISA in order to investigate the interaction between leptospiral endostatin-like protein A and human plasminogen. more
total:6
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 to the paper
Santa Cruz Biotechnology anti-PAK-2 antibody was used for western blot in order to investigate the role of PAK-2 in the regulation of anticancer drug-induced cell apoptosis. more
total:2
Oxysterols are substrates for cholesterol sulfotransferase. 2007 to the paper
Dr. Charles A. Strott (National Institute of Child Health and Human Development) PAPSS1 (1:2,000; HL4004) antibody was used in western blot to identify oxysterols as substrates for cholesterol sulfotransferase more
total:175
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Abcam anti-PARP1 was used to perform western blot in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:51
Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma. 2008 to the paper
Upstate mouse monoclonal anti-paxillin was used to perform immunocytochemistry in order to show that Rho/ROCK/MLC pathway could be inhibited by DCL1 in hepatocellular carcinoma. more
total:15
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-PCAF antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 to the paper
Cayman Chemical PEPCK antibody was used for western blot in order to investigate the role of DBC1 in the regulation of SIRT1 activity and high-fat diet induced liver steatosis in mice.
total:2
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. 2010 to the paper
Cell Signaling ALIX antibody was used to perform western blot in order to indicate an important role for the ubiquitin ligase activity of HOIP in CD40 signaling. more
total:2
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. 2006 to the paper
Chemicon PDE1B1 antibody was used in western blot to study Cellular and subcellular localization of PDE10A. more
total:3
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
Abcam anti-PDE6A antibody(1:200 dilution)was used to perform immunohistochemistry in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
total:2
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
FabGennix anti-PDE6B antibody was used to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
total:2
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
Santa Cruz Biotechnology anti-PDE6G antibody was used to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
total:5
Antiangiogenic characteristics of astrocytes from optic nerve heads with primary open-angle glaucoma. 2008 to the paper
Santa Cruz Biotechnology anti-PDGF-A polyclonal antibody was used to perform western blot in order to study the role of astrocytes on angiogenesis. more
total:5
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-PDGF-B antibody was used in immunohistochemistry to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms. more
total:14
PDGFRalpha/beta expression correlates with the metastatic behavior of human colorectal cancer: a possible rationale for a molecular targeting strategy. 2008 to the paper
Santa Cruz Biotechnology anti-PDGFRA antibody was used to perform Western Blot and immunohistochemistry in order to prove that the metastatic behavior of human colorectal cancer correlates with PDGFRalpha/beta expression. more
total:27
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy. 2009 to the paper
Abgent anti-p-PDGFR Tyr579 antibody was used in immunohistochemistry in order to investigate the mechanism of how Akt mediates sterol regulatory element-binding protein 1 (SREBP-1) cleavage induced by EGFR. more
total:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 to the paper
Chemicon monoclonal anti-perlecan antibody (MAB 1948) was used in frozen sections from mouse and in immunohistochemistry to study the identification of WARP as a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. more
total:1
Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases. 2009 to the paper
Abgent rabbit anti-PFKFB2 (number AP8146a) polyclonal antibody was used to perform western blot in order to demonstrate that overexpression of 6-phosphofructo-2-kinase (PFKFB3) in the nuclear increases cell proliferation via cyclin-dependent kinases.
total:2
Akt regulates the subcellular localization of the Rab27a-binding protein JFC1 by phosphorylation. 2005 to the paper
Santa Cruz Biotechnology phosphoglycerate kinase 1 antibody was used in western blot to study the role of akt in the subcellular localization of JFC1. more
total:3
Phosphofructokinase 1 glycosylation regulates cell growth and metabolism. 2012 to the paper
Santa Cruz Biotechnology anti-PFK1 was used at 1:1000 to perform western blot in order to show that cancer cell growth was regulated by PFK1 glycosylation more
total:1
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. 2010 to the paper
Novus goat anti-PGAM1 antibody was used to carry out western blot analysis in order to clarify an alternative glycolytic pathway in many rapidly proliferating cells.
total:2
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
GeneTex anti-PGD antibody (11,000 diluted in PBS-T/1% milk) was used to perform western blot in order to study the function of quiescent fibroblasts. more
total:6
The DEAD-box protein Dhh1 promotes decapping by slowing ribosome movement. 2012 to the paper
Invitrogen anti-Pgk1 antibody was used to perform western blot to study the role of Dhh1 in the decapping and turnover of mRNA. more
total:6
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz polyclonal anti-p110beta antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:5
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz anti-p110delta monoclonal antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Millipore polyclonal anti-human p85 antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
total:35
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. 2009 to the paper
Santa Cruz Biotechnology anti-PKCdelta antibody was used in western blot to study the mechanism underlying PKCalpha suppressing tumor in the intestine. more
total:20
GABAA receptor trafficking is regulated by protein kinase C(epsilon) and the N-ethylmaleimide-sensitive factor. 2010 to the paper
Santa Cruz Biotechnology goat anti-PKC epsilon antibody was used to perform western blot and immunocytochemistry in order to show that NSF and PKC epsilon could regulate GABAA receptor trafficking to affect synaptic inhibition. more
total:25
Alleviating neuropathic pain hypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex. 2010 to the paper
Invitrogen anti-PKC-zeta (1:500) antibody was used in western blot in order to investigate the role of PKM-zeta on neuropathic pain hypersensitivity in cortex. more
total:1
Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes. 2009 to the paper
Abcam anti-pyruvate kinase antibody was used to perform western blot in order to study the proteomic of the keratinocytes after the treatment of low dose arsenic and ionizing radiation exposure.
total:4
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. 2011 to the paper
Abcam goat anti-PKM1/2 was used in 1:2000 to perform western blot in order to show that antioxidant responses could be achieved by pyruvate kinase M2 inactivation. more
total:30
The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection.. 2009 to the paper
Epitomics rabbit monoclonal phospho-PKR antibody was used to perform western blot in order to investigate the relations between E1B-55K/E4orf6 and eIF2. more
total:32
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-PLCG1 antibody was used to carry out western blot analysis and immunoprecipitation assays in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:1
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 to the paper
Santa Cruz anti-the large subunit of RNA polymerases II antibody (N20) was used in western blot to study the role for the STAGA subunit ADA2b in regulating human GCN5 catalysis.
total:19
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. 2008 to the paper
Santa Cruz anti-PP1alpha was used to perform western blot in order to show that SRC-3/AIB1 coactivator function and turnover is regulated by essential phosphatases and a phospho-degron of SRC-3/AIB1 is primary determinants of its turnover. more
total:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2Ac antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:2
Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma. 2007 to the paper
Santa Cruz Biotechnology goat polyclonal PP1 gamma C antibody was used in western blot to study the regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma more
total:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate polyclonal anti-PP2A-A antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 to the paper
Sigma-Aldrich polyclonal antibody to the PP2APR65 subunit was used to perform western blot in order to investigate the functions of salt-inducible kinase-1. more
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
total:9
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIalpha was used in immunohistochemistry to detect the PKA subunit RIalpha in human adrenal samples more
total:9
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Santa Cruz Biotechnology anti-PKA RII antibody was used in immunoprecipitation in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
total:3
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIIbeta was used in immunohistochemistry to detect the PKA subunit RIIbeta in human adrenal samples more
total:12
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. 2007 to the paper
Cell Signaling Technology phospho-Pan-PKC antibody (1:1,000) was used in western blot to study melanoma cell motility by the Wnt5A/protein kinase C pathway through the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition more
total:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKCtheta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
total:8
Integration of HIV-1 DNA is regulated by interplay between viral rev and cellular LEDGF/p75 proteins. 2010 to the paper
R&D Systems anti-LEDGF/ p75 antibody was used to perform immunoprecipitation, immunocytochemistry, and western blot in order to study the regulation of HIV-1 DNA integration by viral Rev and cellular LEDGF/p75s interplay. more
total:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 to the paper
Abcam C2 proteasome antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway more
total:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Santa Cruz Biotechnology anti-Psc3 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International mouse monoclonal anti-human 20S proteasome subunit alpha4 was used for immunohistochemistry to investigate the effect of immunoproteasome on the Multiple Sclerosis pathogenesis. more
total:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Enzo Life Sciences anti-alpha7 antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:2
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta1 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD). more
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP7 antibody was used for immunohistochemistry to study the effect of immunoproteasome on the Multiple Sclerosis. more
total:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP2 antibody was used to perform immunohistochemistry to study the role of immunoproteasome in the Multiple Sclerosis pathogenesis. more
total:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 to the paper
Cell Signaling Technology anti-phospho-Ser235/236-S6 antibody was used to perform immunocytochemistry in order to study the capacity of rapamycin to provide neuroprotection in Parkinson disease models. more
total:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 to the paper
New England BioLabs antiphospho-p44/42 MAPK antibody and p44/42 MAPK antibody (PhosphoPlus p44/42 MAPK antibody kit) was used in western blot to study the physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing RhoGEFs.
total:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S2 subunit antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication.
total:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S5a antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication. more
total:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p27 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International rabbit polyclonal anti-PA28alpha antibody was used for immunohistochemistry to determine the role of immunoproteasome in the Multiple Sclerosis. more
total:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 to the paper
BIOMOL anti-proteasome activator 28 subunit beta (PA28beta) antibodoy was used to perform western blot in order to confirm the effect on the expression of proteasome-interacting proteins caused by chronic ethanol feeding.
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
total:1
The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response. 2008 to the paper
R&D Systems anti-RAE-1 antibody was used in flow cytometry in order to study the role of immune responses in the tumorigenicity of embryonic stem cells
total:46
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. 2010 to the paper
Santa Cruz Biotechnology anti-RAF1 antibody was used to perform western blot in order to study the role of microRNA-7 in tongue squamous cell carcinoma cells. more
total:17
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-RAN antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
total:4
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
Santa Cruz polyclonal anti-RanBP2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:4
Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation. 2008 to the paper
Santa Cruz aiti-CRBP-1 antibody was used to perform western blot in order to show that differential TGF-beta signaling can activate the stellate cells after liver injury. more
total:5
Poxvirus ankyrin repeat proteins are a unique class of F-box proteins that associate with cellular SCF1 ubiquitin ligase complexes. 2008 to the paper
Lab Vision rabbit-anti-RBX1 antibody was used in western blot in order to identify the poxviral motif as a functional F-box more
total:3
A survivin-ran complex regulates spindle formation in tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-human RCC1 antibody was used to perform western blot in order to study the role of survivin-Ran signaling in spindle formation in tumor cells. more
total:1
Apolipoprotein c1 association with hepatitis C virus. 2008 to the paper
Anogen mouse monoclonal anti-HCV core protein antibody (MO-I40015B) was used in immunocytochemistry to study the association of apolipoprotein C1 with hepatitis C virus.
total:1
ATM localization and gene expression in the adult mouse eye. 2009 to the paper
Santa Cruz Biotechnology goat polyclonal anti-recoverin antibody was used in immunohistochemistry to incubate with the sections in order to determine the ATM expression patterns and studied its localization.
total:2
Differential expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age rats. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal anti-RGS9 antibody (1:100) was used in immunohistochemistry to study the different expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age rats. more
total:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoA antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:12
Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. 2009 to the paper
Abcam mouse anti-rhodopsin antibody was used for western blot in order to investigate the roles of Cep70 and Cep131 in the regulation of ciliogenesis in zebrafish embryos. more
total:1
Overexpression of ribosomal protein L15 is associated with cell proliferation in gastric cancer. 2006 to the paper
Neomarker anti-RPL15 antibody was used in western blot and immunohistochemistry to study the relation between overexpression of ribosomal protein L15 and cell proliferation in gastric cancer.
total:1
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. 2008 to the paper
Bethyl Laboratories rabbit anti-Rpl26 antibody was used for western blot in order to investigate the role of nucleolar protein B23 in the regulation of the vertebrate SUMO pathway.
total:1
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. 2008 to the paper
Abnova rabbit anti-RPL37A antibody was used for western blot in order to investigate the role of nucleolar protein B23 in the regulation of the vertebrate SUMO pathway.
total:3
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Cell Signaling Technology rpS3 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay. more
total:3
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. 2010 to the paper
Cell Signaling Technology anti-rictor antibody was used to carry out western blot analysis in order to investigate the precise contribution of 4E-BPs to mTORC1 signaling. more
total:69
RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. 2011 to the paper
Santa Cruz anti-Rpb1 was used to perform western blot and ChIP assay in order to show that histone mRNA 3 end processing needs the phosphorylation of RNAP II CTD Thr4. more
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Invitrogen rpL11 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:2
RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits. 2010 to the paper
Abcam goat anti-human RPL7 antibody was used to perform western blot in order to study the role of RRP1B and PP1 in mammalian cell nucleoli and pre-60S ribosomal subunits. more
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Cell Signaling Technology rpL7a antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:1
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. 2008 to the paper
Proteintech Group rabbit anti-RplP0 antibody was used for western blot in order to investigate the role of nucleolar protein B23 in the regulation of the vertebrate SUMO pathway.
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abcam rpS16 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:3
Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation. 2009 to the paper
Millipore anti-Mps1 antibody was used to perform immunohistochemistry in order to study the regulation of Mps1 phosphorylation in kinetochore targeting and spindle checkpoint signaling. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:36
p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. 2012 to the paper
Cell Signalling anti-S6 (rabbit monoclonal) antibody was used to perform immunoblotting in order to study the effect of p180 on the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. more
total:2
Hypoxia-induced energy stress inhibits the mTOR pathway by activating an AMPK/REDD1 signaling axis in head and neck squamous cell carcinoma. 2008 to the paper
Cell Signaling Technology rabbit polyclonal anti-phospho-p70 S6 kinase (Thr389) antibody was used for western blot in order to investigate the role of hypoxia-induced energy stress in the regulation of mTOR pathway in head and neck squamous cell carcinoma1. more
total:2
67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells. 2005 to the paper
Abcam polyclonal 67LR antibody (Ab711) was used in western blot and immunoprecipitation to study the role of 67-kDa Laminin Receptor Escherichia coli K1 internalization in human brain microvascular endothelial cells more
total:4
Arrestin competition influences the kinetics and variability of the single-photon responses of mammalian rod photoreceptors. 2009 to the paper
Affinity BioReagent arrestin antibody was used in western blot to investigate the role of arrestin in mammalian rod's single-photon responses more
total:2
Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells. 2005 to the paper
Seikagaku HSPG neo-epitope (exposed after heparitinase III digestion, clone 3G10) antibody was used in western blot to study thrombin-induced human vascular smooth muscle cell migration and proliferation more
total:1
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue. 2006 to the paper
Zymed Laboratories rabbit anti syndecan-3 antibody was used in immunohistochemistry to study its expression in human uterine tissue during prolonged labour
total:3
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans. 2008 to the paper
Santa Cruz Biotechnology anti-syndecan-4 antibody was used in immunocytochemistry to study the effect of heparanase on cell adhesion and spreading. more
total:3
Serum amyloid P colocalizes with apolipoproteins in human atheroma: functional implications. 2007 to the paper
Calbiochem rabbit polyclonal SAP antibody was used in immunohistochemistry to study the colocalization of serum amyloid P with apolipoproteins in human atheroma more
total:1
Study of the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma. 2007 to the paper
Santa Cruze SH3GL2 goat polyclonal antibody was used in western blot to study the SH3-study the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma.
total:20
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Cell Signalling anti-ShcA and anti-phospho-ShcA (Tyr239/240) antibodies were used to perform western blot in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:34
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-Shp2 antibody was used to perform western blot in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
total:8
APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. 2009 to the paper
Zymed mouse monoclonal anti-Skp1 antibody was used in western blot to investigate the regulation of Cdc20 stability during SAC activation in mammalian cells and explore the contribution of spindle checkpoint proteins to Cdc20 stability. more
total:2
TRE-dependent transcription activation by JDP2-CHOP10 association. 2008 to the paper
Santa Cruz THTR1 polyclonal antibody was used in ChIP assays in order to identify CHOP10 as a novel protein associating protein for JDP2 more
total:1
Differentiation-dependent up-regulation of intestinal thiamin uptake: cellular and molecular mechanisms. 2005 to the paper
Sigma-Genosys polyclonal anti-hTHTR-2 antibody was used in western blot to study the association of intestinal thiamin uptake with differentiation.
total:4
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
Sigma-Aldrich mouse anti-DIC antibody was used in western blot (1:1,000) and immunocytochemistry (1:200) in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation. more
total:3
Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-ANT antibody was used for western blot in order to investigate the role of Ischaemic preconditioning in the regulation of proteasomal activity and the degradation of PKCdelta during reperfusion. more
total:1
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. 2007 to the paper
Dr. Douglas C. Wallace (University of California, Irvine) ANT2-specific antiserum was used in western blot to study the regulation of insulin secretion by SIRT4
total:2
Essential role of glucose transporter GLUT3 for post-implantation embryonic development. 2009 to the paper
Santa Cruz Biotechnology Goat anti-GLUT3 antibody was used in immunostaining of blastocysts in order to indicate that GLUT3 is important in early embryonic development. more
total:2
Involvement of an enterocyte renin-angiotensin system in the local control of SGLT1-dependent glucose uptake across the rat small intestinal brush border membrane. 2007 to the paper
Abcam anti-SGLT1 rabbit polyclonal antibody (1 : 600) was used in western blot to assesse the effects of AII on SGLT1-dependent glucose transport across the brush border membrane (BBM). more
total:74
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. 2010 to the paper
Cell Signaling anti-Smad2 was used to perform western blot in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia more
total:51
Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation. 2009 to the paper
Zymed Smad3 polyclonal antibody was used in western blot in order to investigate the role of BMP9 signalling via ALK2/Smad1/Smad4 pathway in ovarian cancer. more
total:21
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 to the paper
Santa Cruz rabbit anti-Smad4(H-552; 1:1,000) antibody was used to perform western blot in order to study the dynamical regulation of TGF-beta signaling during late lung development in the human and mouse. more
total:12
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. 2010 to the paper
Invitrogen anti-Smad7 was used to perform western blot in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia more
total:11
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Affinity Bioreagents anti-SMRT antibody was used to perform western blot in order to show that IRF5 mediates the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:3
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smurf1 antibody was used to carry out western blot analysis and immunohistochemistry assays in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
total:3
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smurf2 antibody was used to carry out western blot analysis and immunohistochemistry assays in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
total:11
Fast vesicle fusion in living cells requires at least three SNARE complexes. 2010 to the paper
Synaptic Systems polyclonal anti-SNAP-25 antibody was used to carry out western blot analysis in order to investigate how many SNARE complexes are required for exocytosis fusion. more
total:5
Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. 2013 to the paper
Santa Cruz anti-SnoN antibody was used to perform western blot to study the role of BMP-Smad signaling during motor axon extension. more
total:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Santa Cruz rabbit Sos-1 antibody was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation. more
total:70
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene. 2010 to the paper
Santa Cruz anti-Sp1 antibody was used to perform ChIP assay in order to study the regulatory function of Sp1 and KLF15 on basal transcription of the human LRP5 gene. more
total:2
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. 2009 to the paper
Upstate anti-SPRY2 antibody was used for western blot in order to investigate the role of BRAF in the regulation of RAF-MEK signaling pathway. more
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:2
FACT facilitates chromatin transcription by RNA polymerases I and III. 2009 to the paper
Abcam anti-SSRP1 was used to perform immunoprecipitation in order to to determine whether indeed FACT associates with Pol I complexes. more
total:1
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
ProteinTech Group STAM-1 polyclonal antibody was used to perform western blot and immunoprecipitation in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS.
total:84
T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response. 2010 to the paper
Santa Cruz Biotechnology anti-STAT1 polyclonal antibody was used to perform immunohistochemistry in order to study the transcriptional features of T-cell/histiocyte-rich large B-cell lymphoma. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:51
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Santa Cruz Biotechnology anti-STAT5 antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
total:23
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 2009 to the paper
Upstate Biotech-Millipore anti-P-STAT5B (Y699) antibody was used in western blot in order to characterize the role of ERBB4 mutations in melanoma. more
total:1
Absence of gemin5 from SMN complexes in nuclear Cajal bodies. 2007 to the paper
Dr. Glenn E Morris (RJAH Orthopaedic Hospital) rabbit antiserum against unrip was used in western blot and immunocytochemistry to study the absence of gemin5 from SMN complexes in nuclear Cajal bodies
total:1
The role of Snapin in neurosecretion: snapin knock-out mice exhibit impaired calcium-dependent exocytosis of large dense-core vesicles in chromaffin cells. 2005 to the paper
Santa Cruz Biotech anti-Syntaxin-1B antibody was used in western blot to study the role of Snapin in neurosecretion.
total:2
Transcription termination factor Pcf11 limits the processivity of Pol II on an HIV provirus to repress gene expression. 2007 to the paper
Santa Cruz Biotechnology anti-Spt5 (sc-28678) antibody was used in western blot to study the role of transcription termination factor Pcf11 on the processivity of Pol II more
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more
total:11
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-syntaxin-1 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
total:7
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-TAF1 antibody was used to perform Chip in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
total:2
SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation. 2009 to the paper
Upstate Biochemistry amti-RNA polymerase II antibody was used for immunoprecipitation in order to indicate that SUMOylation is mediated through reduced CDK7-induced phosphorylation of SF-1. more
total:2
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-TAF11 antibody was used to perform Chip or Web in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
total:2
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 to the paper
Irwin Davidson TAF12 antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires. more
total:1
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 to the paper
Irwin Davidson TAF4 antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires.
total:1
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Sigma-Aldrich anti-TAF5 antibody was used to perform Chip in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters.
total:1
Core promoter binding by histone-like TAF complexes. 2005 to the paper
Santa Cruz Biotechnology anti-TAF9 antibody was used in western blot, immunoprecipitation, and EMSA to study histone-like TAF complexes
total:14
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-TBP antibody was used to perform Chip or Web in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
total:4
Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome. 2008 to the paper
Santa Cruz anti-Elongin B antibody was used in immunoprecipitation in order to demonstrate that SAP130 may link CRL mediated ubiquitination to gene expression. more
total:1
Zinc status and vacuolar zinc transporters control alkaline phosphatase accumulation and activity in Saccharomyces cerevisiae. 2009 to the paper
Molecular Probes anti-Vph1 was used in western blot to investigate the role of the Zrc1 and Cot1 vacuolar zinc transporters in the regulation of Pho8 protein activity and accumulation.
total:1
Identification and characterization of novel isoforms of human DP-1: DP-1{alpha} regulates the transcriptional activity of E2F1 as well as cell cycle progression in a dominant-negative manner. 2005 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-DP-1 antibody was used in western blot to identify and Characterize the novel isoforms of human DP-1.
total:8
Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin. 2009 to the paper
Santa Cruz anti-TFIIB antibody was used to perform ChIP assays in order to study the association between the papillomavirus E2 proteins, the host Brd4 protein and the transcriptionally active cellular genes. more
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
total:3
TGFBI expression is associated with a better response to chemotherapy in NSCLC. 2010 to the paper
Proteintech group anti-TGFBI antibody was used to perform immunohistochemistry in order to determine the association between TGFBI expression and the response to chemotherapy in NSCLC. more
total:15
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-TGFBR1 antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
total:21
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 to the paper
Santa Cruz rabbit anti-Tgfbr2(C-16; 1:50; used with blocking peptide SC-220P; catalog no. SC-220) antibody was used to perform immunohistochemistry and western blot in order to study the dynamical regulation of TGF-beta signaling during late lung development in the human and mouse. more
total:1
Hepatocyte growth factor receptor signaling mediates the anti-fibrotic action of 9-cis-retinoic acid in glomerular mesangial cells. 2005 to the paper
Santa Cruz Biotechnology anti-TGIF antibody was used in western blot to study the effects of 9-cis-RA on glomerular mesangial cell activation induced by transforming growth factor (TGF) beta1.
total:1
Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA-binding protein with broad RNA targets. 2006 to the paper
Minoru S. H. Ko (National Institutes of Health) anti-ESG1 polyclonal antibody was used in western blot and immunohistochemistry to demonstrate that ESG1 is an RNA-binding protein.
total:1
Protein expression profiling in the spectrum of renal cell carcinomas. 2010 to the paper
Proteintech rabbit anti-TPI-1 antibody(1 ug/ml) was used to perform immunostaining in order to study the differentiation in renal cell carcinomas(RCC) followed by specific protein expression.
total:4
Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of keratoepithelin. 2005 to the paper
Dako polyclonal anti-transthyretin antibody was used in immunohistochemistry to study the association of hereditary lattice corneal dystrophy with corneal amyloid deposits enclosing C-terminal fragments of feratoepithelin. more
total:2
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. 2008 to the paper
EMD Chemicals anti-TRB3 antibody was used to perform western blot in order to study the response of the mTORC1 signaling after the inhibition of protein synthesis. more
total:1
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 to the paper
Abcam anti-TRIM24 antibody was used to perform western blot in order to study the novel BRAF fusion gene in 7q34 duplication of pediatric low-grade astrocytomas detected by high density SNP-based genotype array analysis.
total:26
Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression. 2010 to the paper
Epitomics anti-TSC2 antibody was used to perform western blot and immunoprecipitation in order to study the mechanism by which carboxy terminal tail of polycystin-1 repress mTOR signaling via membrane retention of TSC2. more
total:15
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Abcam monoclonal anti-Tsg101 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:1
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes. 2007 to the paper
Boston Biochem anti-UbcH5 antibody was used to perform immunoprecipitation in order to study the roles of the DET1 during the regulation of the Cul4A activity.
total:1
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. 2010 to the paper
Abcam anti-UbcH5c antibody was used to perform western blot in order to study the mechanism of A20 action in the inhibition of NF-kappaB signaling.
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:1
CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha. 2007 to the paper
Abnova USP15 antibody was used in western blot to demonstrate that CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha.
total:8
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-synaptobrevin-2 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
total:4
Expression of ZIC family genes in meningiomas and other brain tumors. 2010 to the paper
Sigma-Aldrich anti-chondroitin sulfate proteoglycan antibody was used to perform immunohistochemistry in order to investigate the expression profiles of ZIC genes in brain tumors. more
total:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 to the paper
Bethyl Laboratories NAMPT antibody was used for western blot in order to investigate the role of DBC1 in the regulation of SIRT1 activity and high-fat diet induced liver steatosis in mice.
total:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 to the paper
Bethyl Laboratory Inc. rabbit anti-SKD1 antibody was used in western blot to study the interaction of the mammalian endosomal sorting complex required for rransport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1
total:7
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. 2009 to the paper
Santa Cruz Biotechnology CRM-1 antibody was used for Western blotting in order to investigate the effect of LKB1 on nucleocytoplasmic transport. more
total:3
Adeno-associated virus replication induces a DNA damage response coordinated by DNA-dependent protein kinase. 2009 to the paper
Serotech anti-XRCC4 antibody was used to carry out western blot analysis in order to investigate the effect of adeno-associated virus and adenovirus coinfection on inducing cellular DNA damage response. more
total:1
The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells. 2005 to the paper
Santa Cruz Biotechnology goat anti-SARA (N-20) antibody was used in immunoprecipitation and western blot to study the role of internalization in transforming growth factor 1-induced smad2 association with smad anchor for receptor activation (SARA) and smad2-dependent signaling in human mesangial cells