Developmental Biology
gene
reagent
sample publication
sample review
14 3 3 protein beta alpha
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
total:9
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3beta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
abl
ABL proto-oncogene 1, non-receptor tyrosine kinase
total:35
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Calbiochem c-Abl antibody (1:1,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
ABL2
ABL proto-oncogene 2, non-receptor tyrosine kinase
ABLIM2
actin binding LIM protein family member 2
ACVR2B
activin A receptor type 2B
total:2
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1. 2005 to the paper
R & D Systems anti-Act-RIIb was used to perform western blot in order to show that in mature human B cells BMP-6 could regulate Smad phosphorylation, Id1 expression, and cell growth. more
adiponectin
adiponectin, C1Q and collagen domain containing
total:6
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 to the paper
Calbiochem rabbit polyclonal antibody against adiponectin was used in western blot and immunoprecipitation to investigate the role of DLK in the regulation of 3T3-L1 adipocyte differentiation. more
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Akt
AKT serine/threonine kinase 1
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
AKT3
AKT serine/threonine kinase 3
total:4
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. 2008 to the paper
Millipore anti-Akt3 was used to perform western blot in order to show that PTEN-null tumors is promoted to autophagy and more sensitive to lysosomotropic agents after Akt inhibition. more
ALCAM
activated leukocyte cell adhesion molecule
total:5
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
BD Biosciences anti-CD166 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
alpha-adaptin
adaptor related protein complex 2 subunit alpha 1
total:17
FCHo proteins are nucleators of clathrin-mediated endocytosis. 2010 to the paper
Transduction Laboratories mouse monoclonal anti-AP2A1 antibody was used to carry out western blot analysis in order to investigate the roles for FCHo1 and FCHo2 proteins in clathrin-mediated endocytosis in cell plasma membrane. more
alpha-catenin
catenin alpha 1
total:24
Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma. 2010 to the paper
BD Biosciences anti-a-catenin antibody was used to perform western blot in order to study the role of LMP2A in the nasopharyngeal carcinoma progression. more
ANGPTL4
angiopoietin like 4
total:1
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. 2005 to the paper
Karen S. L. Lam (University of Hong Kong, China) monoclonal ANGPTL4 antibody was used in ELISA to study its effect in mice
ANK3
ankyrin 3
total:1
The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells. 2005 to the paper
Zymed Laboratories mouse anti-human ankyrin-G monoclonal antibody was used in immunohistochemistry to detect ankyrin-G in rat kidney sections and in immnocytochemistry to stain for ankyrin-G in MDCK cells.
AP2A2
adaptor related protein complex 2 subunit alpha 2
total:5
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
Sigma anti-alpha-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. more
AP2B1
adaptor related protein complex 2 subunit beta 1
total:5
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1/2b antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
AP2M1
adaptor related protein complex 2 subunit mu 1
total:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 to the paper
BD Biosciences monoclonal anti-AP50 antibody was used in human HeLa cells or HUVECs and in western blot to study the role for clathrin adaptor AP2 in regulating thrombin receptor constitutive internalization and endothelial cell resensitization. more
ARHGAP35
Rho GTPase activating protein 35
total:3
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 to the paper
BD Biosciences anti-p190RhoGAP was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis. more
beta-catenin
catenin beta 1
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
beta1 integrin
integrin subunit beta 1
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
BOC
BOC cell adhesion associated, oncogene regulated
c-Met
MET proto-oncogene, receptor tyrosine kinase
total:30
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. 2009 to the paper
R&D rabbit anti-pMET antibody was used to perform immunohistochemistry in order to study the function of the fixative in the immunohistochemical detection of phosphoproteins. more
C/EBPalpha
CCAAT enhancer binding protein alpha
total:21
C/EBPalpha or C/EBPalpha oncoproteins regulate the intrinsic and extrinsic apoptotic pathways by direct interaction with NF-kappaB p50 bound to the bcl-2 and FLIP gene promoters. 2009 to the paper
Affinity Bioreagents mouse anti-C/EBPa antibody was used to carry out immunoprecipitation assay and western blot analysis in order to investigate the mechanism for oncoprotein C/EBPa cooperated with NF-kB p50 to inhibit apoptosis. more
C/EBPbeta
CCAAT enhancer binding protein beta
total:26
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. 2009 to the paper
Santa Cruz Biotechnology C/EBPbeta antibody was used in ChIP assay to study the regulation of aromatase transcription and estrogen biosynthesis in adipose stromal cells (ASCs). more
CACNA1C
calcium voltage-gated channel subunit alpha1 C
total:11
The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. 2010 to the paper
Chemicon anti-CaV1.2 antibody was used to carry out western blot analysis in order to investigate the role for STIM1 in coordinating Voltage- and store-operated calcium channels to generate coherent calcium signals. more
CACNA1D
calcium voltage-gated channel subunit alpha1 D
total:3
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav1.3 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels. more
CACNA1G
calcium voltage-gated channel subunit alpha1 G
total:1
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav3.1 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels.
CACNA1I
calcium voltage-gated channel subunit alpha1 I
total:1
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav3.3 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels.
CACNB1
calcium voltage-gated channel auxiliary subunit beta 1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
CAP1
cyclase associated actin cytoskeleton regulatory protein 1
total:1
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Abnova mouse anti-CAP1 antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking.
CAP2
cyclase associated actin cytoskeleton regulatory protein 2
CBP
CREB binding protein
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
CD24
CD24 molecule
total:10
Identification of potential therapeutic targets in human head & neck squamous cell carcinoma. 2009 to the paper
Chemicon anti-CD24 antibody was used to perform immunohistochemistry in order to find out the potential therapeutic targets of the human head and neck squamous cell carcinoma. more
CD36
CD36 molecule
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
CD41
integrin subunit alpha 2b
total:13
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD41 was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
CD45
protein tyrosine phosphatase receptor type C
total:123
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Invitrogen biotin-labeled anti-CD45 mAb was used for cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
CD56
neural cell adhesion molecule 1
total:56
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD56 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
Cdc2
cyclin dependent kinase 1
total:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk1 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
cdc42
cell division cycle 42
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
cdc42
cell division cycle 42
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
CDH15
cadherin 15
total:1
Long-term survival of transplanted stem cells in immunocompetent mice with muscular dystrophy. 2008 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-M-cadherin antibody was used in flow cytometry at 1:50 in order to study the role of duchenne muscular dystrophy in the long-term survival of transplanted stem Cells
Cdk5
cyclin dependent kinase 5
total:8
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 to the paper
Santa Cruz Biotechnology anti-Cdk5 (SC-173), Cdk5-pTyr-15 (SC-12918), and Cdk5-pSer-159 (SC-12919) antibodies were used to perform western blot in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration. more
CDK5R1
cyclin dependent kinase 5 regulatory subunit 1
total:8
Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion. 2008 to the paper
Alexis Biochemicals polyclonal anti-p23 antibody was used in western blot in order to study the role of acetylation and extra-cellular location of heat shock protein 90alpha in tumor cell invasion more
CDK8
cyclin dependent kinase 8
total:5
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK8 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
CDO
cell adhesion associated, oncogene regulated
CEBPD
CCAAT enhancer binding protein delta
total:4
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 to the paper
Santa-Cruz Biotechnology anti-C/EBP delta antibody was used to carry out western blot analysis in order to investigate the role for NF-kB transcription factor in the interleukin-1 induced expression of C/EBP delta and APP genes. more
CFL1
cofilin 1
total:8
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Sigma-Aldrich polyclonal anti-cofilin and anti-phospho-cofilin antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
CHL1
cell adhesion molecule L1 like
total:2
Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. 2010 to the paper
R&D Systems goat anti-CHL1 antibody (1:500) was used for western blot in order to investigate the role of PKCdelta in the regulation of CHL1 expression in cultured astrocytes.. more
CLASP1
cytoplasmic linker associated protein 1
total:1
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GFP monoclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease.
CLASP1
cytoplasmic linker associated protein 1
total:1
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GFP monoclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease.
CLTA
clathrin light chain A
total:5
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Sigma-Aldrich monoclonal anti-clathrin light chain antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
CNTNAP1
contactin associated protein 1
total:1
Nav1.7 expression is increased in painful human dental pulp. 2008 to the paper
Neuromab mouse monoclonal anti-caspr (catalog #75-001, 1:500) antibody was used in immunohistochemistry to study Nav1.7 expression in painful human dental pulp
COL4A1
collagen type IV alpha 1 chain
total:9
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
Abcam anti Col IV antibody was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
COL4A3
collagen type IV alpha 3 chain
total:5
Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. 2005 to the paper
Santa Cruz Biotechnology goat anti-alpha3 antibody was used in western blot to study the effect of activation of vascular endothelial growth factor receptor 3 on endothelial function and infection. more
COL4A4
collagen type IV alpha 4 chain
total:2
ELR-negative CXC chemokine CXCL11 (IP-9/I-TAC) facilitates dermal and epidermal maturation during wound repair. 2008 to the paper
Abcam rabbit polyclonal collagen IV antibody was used in immunohistochemistry in order to study the role of IP-10 and IP-9 in epidermal maturation during wound repair more
COL6A1
collagen type VI alpha 1 chain
total:2
The extracellular matrix glycoprotein elastin microfibril interface located protein 2: a dual role in the tumor microenvironment. 2010 to the paper
Santa Cruz Biotechnology anti-type I collagen antibody was used in western blot in order to investigate the function of the 90-amino acid residue fragment of elastin microfibril interface located protein 2 (EMILIN2) in the tumor microenvironment. more
COL9A1
collagen type IX alpha 1 chain
total:2
Alteration of medial-edge epithelium cell adhesion in two Tgf-beta3 null mouse strains. 2008 to the paper
Developmental Studies Hybridoma Bank 1:50 monoclonal mouse IgG anti-sheep collagen IX antibody was used in immunohistochemistry in order to study the role of growth factor TGF-b3 in palatal shelf adhesion more
CREB
cAMP responsive element binding protein 1
total:58
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
CRMP1
collapsin response mediator protein 1
total:1
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 to the paper
BD Biosciences-Pharmingen monoclonal anti-Drp1 antibody was used in immunohistochemistry in order to introduce a rapid regulation of mitochondrial dynamics in acute kidney injury.
CSNK2A1
casein kinase 2 alpha 1
total:9
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 to the paper
Santa-Cruz Biotechnology anti-CK2 alpha antibody was used to carry out western blot analysis in order to investigate the role for NF-kB transcription factor in the interleukin-1 induced expression of C/EBP delta and APP genes. more
CSNK2A2
casein kinase 2 alpha 2
total:4
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 to the paper
Santa-Cruz Biotechnology anti-CK2 alpha' antibody was used to carry out western blot analysis in order to investigate the role for NF-kB transcription factor in the interleukin-1 induced expression of C/EBP delta and APP genes. more
CSNK2B
casein kinase 2 beta
total:2
CK2beta is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation. 2009 to the paper
Santa Cruz anti-CK2B antibody was used to perform western blot and immunohistochemistry in order to show the role of CK2B in apoptosis resistance and cell proliferation in endometrial carcinoma. more
CTNNA2
catenin alpha 2
total:2
Epicardium-derived progenitor cells require beta-catenin for coronary artery formation. 2007 to the paper
Abcam 1:5,000 diluted beta-catenin antibody was used in immunohistochemistry to study the role of beta-catenin in coronary artery formation in epicardium-derived progenitor cells. more
DAP12
transmembrane immune signaling adaptor TYROBP
DCC
DCC netrin 1 receptor
total:2
Netrin-1 inhibits leukocyte migration in vitro and in vivo. 2005 to the paper
Santa Cruz Biotechnology goat anti-mouse DCC antibody was used in immunocytochemistry to study the effect of netrin-1 on leukocyte migration more
DLG1
discs large MAGUK scaffold protein 1
total:6
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. 2006 to the paper
Affinity BioReagents SAP97 antibody (1:3000) was used in western blot to demonstrate that dendritic A-type K+ channels regulate action potential backpropagation and the induction of specific forms of synaptic plasticity. more
DLG3
discs large MAGUK scaffold protein 3
total:2
Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway. 2006 to the paper
Developmental Studies Hybridoma Bank mouse anti-Dlg (discs large) antibody was used in western blot to test contributions of four specific functional sites in beta spectrin to its assembly and function. more
DNM2
dynamin 2
total:6
Mechanisms of Chlamydia trachomatis entry into nonphagocytic cells. 2007 to the paper
BD Biosciences anti-dynamin-2 antibody was used to carry out immunofluorescence assays in order to investigate the mechanism of entry for Chlamydia trachomatis into nonphagocytic cells. more
DNM3
dynamin 3
total:2
Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef. 2007 to the paper
Affinity BioReagents anti-Dyn3 antibody was used in western blot in order to investigate the mechanism of how dynamin 2 (a binding partner of Nef) enhances the infectivity of HIV-1. more
doublecortin
total:6
Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia. 2011 to the paper
Millipore guinea pig anti-DCX antibody(1:500)was used to perform immunocytochemistry in order to investigate the role of retinoic acid in generation of GABAergic neurons in the basal ganglia. more
DPYSL2
dihydropyrimidinase like 2
total:2
Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3. 2009 to the paper
Immuno-Biological Laboratories anti-CRMP-2 antibody was used to perform western blot in order to show that the mutant SOD1 can sequester KAP3 and then reduce the axonal transport of choline acetyltransferase and acetylcholine release. more
DPYSL3
dihydropyrimidinase like 3
total:1
Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. 2008 to the paper
Chemicon polyclonal rabbit anti-CRMP4/Tuc-4 antibody (Cat:AB5454) was used in immunohistochemistry to study what happens in the cerebellar cortex of peripuberal rabbits by using endogenous and exogenously-administered cell proliferation antigens in association with a cohort of typical markers for neurogenesis.
DRAGON
repulsive guidance molecule BMP co-receptor b
Dynamin
dynamin 1
total:15
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Santa Cruz Biotechnology monoclonal anti-dynamin 1 antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
EGFR
epidermal growth factor receptor
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
EPAS1
endothelial PAS domain protein 1
total:9
Characterization of the activation of protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1) by hypoxia inducible factor-2 alpha. 2010 to the paper
Novus Biologicals HIF2alpha antibody was used for ChIP assays in order to study HIF-binding and Ets-binding motifs on the PTPRZ1 promoter and show that PTPRZ1 can be activated by HIF-2. more
EPHA1
EPH receptor A1
total:1
Silencing the receptor EphA2 suppresses the growth and haptotaxis of malignant mesothelioma cells. 2006 to the paper
Zymed Laboratories EphA1 antibody was used in western blot to study the role of receptor EphA2 expression in MM cells (MMCs) in the growth and haptotactic migration of MM.
EPHB2
EPH receptor B2
total:29
Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1. 2011 to the paper
Santa Cruz rabbit anti-ERK antibody was used to perform immunocytochemistry in order to investigate the role of the PKA/AKAP1 complex in the maintenance of mitochondrial integrity and the protection from neuronal injury. more
ERK1
mitogen-activated protein kinase 3
total:252
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Millipore anti-ERK1/2 polyclonal antibody (1:10,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediated anti-apoptotic effects. more
ERK2
mitogen-activated protein kinase 1
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
ezrin
total:27
Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. 2012 to the paper
Cell Signaling anti-Ezrin antibody was used to perform immunoprecipitation in order to study NKCC1 modulation of glioma cell migration. more
FABP4
fatty acid binding protein 4
total:2
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-A-FABP antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
FAK
protein tyrosine kinase 2
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
FARP2
FERM, ARH/RhoGEF and pleckstrin domain protein 2
FES
FES proto-oncogene, tyrosine kinase
total:2
A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer. 2006 to the paper
Santa Cruz goat polyclonal antibodies generated against either Fes amino-terminal (Fes N-19) or carboxyl-terminal (Fes C-19) peptides were used in western blot to investigate Fes expression in human 293T cells, as well as HT-29 and HCT 116 cells, and in immunohistochemstry to detect Fes expression in normal adult human colon sections and human colorectal cancer cell line HT-29. more
FGF-2
fibroblast growth factor 2
total:20
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 to the paper
Chemicon rabbit polyclonal anti-FGF2 antibody was used in western blot to study the role for endothelial-derived FGF2 in the progression of pulmonary hypertension in humans and rodents. more
FGFR1
fibroblast growth factor receptor 1
total:17
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Biosource International anti-FGFR-1 (pYpY653/654) antibodies were used to perform western blot and ELISA analyses in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
FKHR
forkhead box O1
total:20
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-FKHR antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more
FKHRL1
forkhead box O3
total:18
CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16.. 2013 to the paper
Cell Signaling rabbit anti-mFOXO3(phospho-S252)/hFOXO3(phospho-S253) antibody was used to perform western blot in order to investigate the regulatory effect of calcineurin and CAMKII on the lifespan of Caenorhabditis elegans. more
FOXD3
forkhead box D3
total:1
Identification and subclassification of new Atoh1 derived cell populations during mouse spinal cord development. 2009 to the paper
M. Goulding rabbit anti-FOXD3 antibody was used to incubate the embryos slides in order to reveal the existence of Atoh1 dependent cell types in the spinal cord.
FOXH1
forkhead box H1
total:1
Progesterone-dependent deoxyribonucleic acid looping between RUSH/SMARCA3 and Egr-1 mediates repression by c-Rel. 2008 to the paper
Santa Cruz Biotechnology FAST-1/2 antibody was used in ChIP assays in order to demonstrate that self-assembling peptide nanofiber scaffolds accelerate wound healing
Fyn
FYN proto-oncogene, Src family tyrosine kinase
total:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-FYN antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking. more
GDNF
glial cell derived neurotrophic factor
total:4
Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease. 2005 to the paper
Santa Cruz anti-GDNF antibody was used in immunohistochemistry to compare GDNF, BDNF, or both, for their capabilities to correct behavioral deficits and protect nigrostriatal dopaminergic neurons in a rat model of PD.. more
GFRA1
GDNF family receptor alpha 1
total:5
Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation. 2006 to the paper
R & D Systems anti-GFR1 (1:1000) was used in western blot to demonstrate that lipid rafts sequester Ret away from the degradation machinery to sustain Ret signaling. more
GFRA2
GDNF family receptor alpha 2
total:4
MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells. 2008 to the paper
Cell Signaling anti-P-p38 antibody was used to perform western blot in order to investigate the role of the MAPK kinase kinase-1 (MEKK-1) in cytokine-induced signaling pathway. more
glucokinase
total:1
Spermatogenic cell-specific type 1 hexokinase is the predominant hexokinase in sperm. 2008 to the paper
ABGENT anti-GCK(N-term) polyclonal antibody was used to perform immunoblotting in order to study the role of spermatogenic cell-specific type 1 hexokinase(HK1S) in sperm.
GLUT4
solute carrier family 2 member 4
total:11
ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. 2009 to the paper
Millipore anti-Glut4 antibody was used to carry out western blot analysis in order to investigate the regulation of adipocyte glucose transport by ClipR-59 mediated Akt cellular compartmentalization. more
Grb2
growth factor receptor bound protein 2
total:36
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal against Ron antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer. more
GSK3beta
glycogen synthase kinase 3 beta
total:79
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 beta antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
H-Ras
HRas proto-oncogene, GTPase
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
HDAC3
histone deacetylase 3
total:21
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 to the paper
Santa Cruz Biotechnology anti-HDAC3 antibody was used to perform western blot assay in order to identify novel histone deacetylase complexes that promote expansions of trinucleotide repeats. more
HER2
erb-b2 receptor tyrosine kinase 2
total:69
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. 2008 to the paper
Zymed Laboratories anti-c-erbB-2 antibody was used in immunohistochemistry to investigate the relationship between amphiregulin expression and liver metastases of colorectal cancer. more
HES1
hes family bHLH transcription factor 1
total:3
Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer. 2009 to the paper
Chemicon Hes1 antibody was used in western blot in order to generate monoclonal antibodies to evaluate therapeutic potential of targeting EphA2 in pancreatic tumor. more
HNF1B
HNF1 homeobox B
total:5
HNF-1beta regulates transcription of the PKD modifier gene Kif12. 2009 to the paper
Santa Cruz Biotechnology anti-HNF1B antibody was used for western blot in order to investigate the role of HNF-1beta in the regulation of PKD Modifier Gene Kif12. more
HNF4A
hepatocyte nuclear factor 4 alpha
total:12
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-HNF4 alpha antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more
Hsc70
heat shock protein family A (Hsp70) member 8
total:25
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
Stressgen monoclonal anti-Hsc70 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
HSP90
heat shock protein 90 alpha family class A member 1
total:68
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-HSP90 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
HSP90AB1
heat shock protein 90 alpha family class B member 1
total:8
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. 2010 to the paper
Millipore anti-H3S28P antibody was used in western blot in order to investigate the mechanism of how the embryonic stem cells chromatin structure change was regulated by condensin complexes during mitotic progression. more
insulin
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
integrin alpha v
integrin subunit alpha V
total:24
TGFBI expression is associated with a better response to chemotherapy in NSCLC. 2010 to the paper
Chemicon Interational anti-integrin alphavbeta3 monoclonal was used to perform flow cytometry in order to determine if this integrin influences TGFBI-mediated NSCLC cell susceptibility to chemotherapy. more
integrin alpha2
integrin subunit alpha 2
total:15
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha2 antibody (clone P1E6) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
integrin alpha5
integrin subunit alpha 5
total:30
The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis. 2008 to the paper
Chemicon monoclonal anti-alpha5 was used to perform blocking experiments in order to show that integrins could interact with CXCL4 and play a role in angiogenesis. more
integrin beta3
integrin subunit beta 3
total:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal integrin beta3 antibody (1:1000) was used in western blot in order to study the role of activated state of p42/44 and p38 in MMP-13 expression. more
ITGA1
integrin subunit alpha 1
total:11
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha1 antibody (clone FB12) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
ITGA9
integrin subunit alpha 9
total:5
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 to the paper
Proteintech Group anti-RLC antibody was used to perform western blot in order to study the assemble of mammalian nonmuscle myosin II in live cells. more
KCNQ2
potassium voltage-gated channel subfamily Q member 2
total:2
Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons. 2006 to the paper
Chemicon KCNQ2 antibody was used in western blot to study the role of Kv7/KCNQ/M channels in the control of cell excitability. more
KCNQ3
potassium voltage-gated channel subfamily Q member 3
total:1
Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons. 2006 to the paper
Chemicon KCNQ3 antibody was used in western blot to study the role of Kv7/KCNQ/M channels in the control of cell excitability.
KLF4
Kruppel like factor 4
total:2
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. 2008 to the paper
Abcam rabbit anti-KLF4 antibody 1:15,000 was used for western blot in order to investigate the role of eIF4GI in the regulation of cell proliferation and autophagy. more
laminin
laminin subunit beta 1
total:16
Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle. 2008 to the paper
Chemicon rabbit polyclonal laminin antibody was used in immunohistochemistry in order to study the role of talin 1 in the development and function of skeletal muscle more
leptin
total:6
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-Ob antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
LIMK1
LIM domain kinase 1
total:4
Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer. 2007 to the paper
Transduction Laboratories anti-LIMK1 antibody was used in western blot and immunohistochemistry to study the role of LIM kinase 1 in reversible G1/S phase arrest, chromosomal instability and prostate cancer. more
LIMK2
LIM domain kinase 2
total:2
ROCK1 and LIMK2 interact in spread but not blebbing cancer cells. 2008 to the paper
Cell Signalling anti-LIMK2 was used to perform western blot in order to show that ROCK1 could interact with LIMK2 in polarised but not blebbing cancer cells. more
LIN28A
lin-28 homolog A
total:1
Lin28 promotes transformation and is associated with advanced human malignancies. 2009 to the paper
ProteinTech anti-Lin28 antibody was used to perform immunohistochemistry in order to study the roles of Lin28 in tumorigenesis and its association with advanced human malignancies.
MAPK11
mitogen-activated protein kinase 11
total:10
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
Cell Signaling Technologies phospho-specific and total anti-p38antibody was used to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
MED1
mediator complex subunit 1
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-MED1 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
MED12
mediator complex subunit 12
total:2
Mediator modulates Gli3-dependent Sonic hedgehog signaling. 2006 to the paper
Santa Cruz Biotechnology MED12 antibody was used in western blot to study the mechanism by which Gli proteins regulate target gene transcription in the nucleus. more
MED17
mediator complex subunit 17
total:2
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Aviva polyclonal anti-MED17 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
MED23
mediator complex subunit 23
total:4
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
BD Pharmingen monoclonal anti-MED23 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
MED24
mediator complex subunit 24
total:1
leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. 2007 to the paper
Santa Cruz Biotechnology Med24 antibody was used in chromatin immunoprecipitation to study the recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3 by leptin and its stimulation of breast cancer cells.
MED26
mediator complex subunit 26
total:1
High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency. 2010 to the paper
Molecular Probes anti-Complex II 70kD subunit antibody was used to perform western blot in order to study the role of the mutations in NUBPL and FOXRED1 in human complex I deficiency.
MED6
mediator complex subunit 6
total:2
Mediator acts upstream of the transcriptional activator Gal4. 2012 to the paper
Abcam rabbit anti-Med6 polyclonal antibody was used to perform western blot in order to study how the Mediator initiated Gal4 transcription. more
MEF2A
myocyte enhancer factor 2A
total:6
A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation. 2006 to the paper
Santa Cruz monoclonal anti-MEF2 antibody was used in immunoprecipitation to study a mechanism underlying postsynaptic differentiation that may modulate activity-dependent synapse development and plasticity in the brain.. more
MEF2C
myocyte enhancer factor 2C
total:3
c-MYC independent nuclear reprogramming favors cardiogenic potential of induced pluripotent stem cells. 2010 to the paper
Proteintech rabbit anti-Mef2c antibody (10056-1-AP; dilution 1:50) was used to perform immunocytochemistry in order to determine the relationship between the cardiogenic potential of iPS and the nuclear reprogramming. more
MEK1
mitogen-activated protein kinase kinase 1
total:57
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Cell Signaling Technology anti-MEK1 antibody was used to perform flow cytometry and immunochemistry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
MEK2
mitogen-activated protein kinase kinase 2
total:16
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. 2010 to the paper
Cell Signaling Technologies anti-phospho-MEK1/2 antibody was used to perform western blot in order to study the discrimination between the yeast and hyphal forms of C. albicans in epithelial cells via a biphasic MAPK response. more
MKK6
mitogen-activated protein kinase kinase 6
total:9
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. 2008 to the paper
Cell Signaling Technology polyclonal rabbit MKK6 with phosphorylated serine 207 antibody was used in western blot in order to demonstrate that ATM undergoes an activating phosphorylation in syncytia elicited by the envelope glycoprotein complex (Env) of human immunodeficiency virus-1 (HIV-1) in vitro more
moesin
total:10
Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane. 2009 to the paper
NeoMarkers moesin antibody was used in western blot in order to study the role of phospholipase C in rapid cytoskeletal remodeling and the role of PIP2 in hydrolysis-mediated ERM inactivation. more
MYF5
myogenic factor 5
total:2
SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. 2009 to the paper
Santa Cruz Biotechnologies MYF-5 antibody was used to perform western blot in order to show the role of SMD and NMD in myogenesis. more
MYH10
myosin heavy chain 10
total:4
Internalization of large double-membrane intercellular vesicles by a clathrin-dependent endocytic process. 2007 to the paper
BAbCO anti-nonmuscle myosin-IIB antibody was used in immunocytochemistry in order to investigate the mechanism of large, double-membrane vesicles internalization based on clathrin-dependent endocytosis. more
MYH11
myosin heavy chain 11
total:7
Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue. 2008 to the paper
Sigma-Aldrich monoclonal anti-human smooth muscle myosin antibody was used for western blot in order to show that ILK can regulate airway smooth muscle differentiation. more
MYH14
myosin heavy chain 14
total:3
An adhesion-dependent switch between mechanisms that determine motile cell shape. 2011 to the paper
Abcam polyclonal rabbit anti-myosin(ab2480) antibody was used to perform immunofluorescence in order to study the mechanisms of keratocytes behavior determined by adhesion strength. more
MYH9
myosin heavy chain 9
total:3
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 to the paper
Sigma anti-NMHC-IIA antibody was used to perform western blot in order to study the assemble of mammalian nonmuscle myosin II in live cells. more
MyoD
myogenic differentiation 1
total:16
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. 2010 to the paper
Santa Cruz Biotechnology anti-MyoD antibody was used to carry out western blot analysis in order to investigate the regulation of Notch signaling and cell differentiation by mTOR signaling. more
myogenin
total:14
The core binding factor CBF negatively regulates skeletal muscle terminal differentiation. 2010 to the paper
Santa Cruz anti-myogenin antibody was used for western blot in order to study whether core binding factor was involved in the control of skeletal muscle terminal differentiation. more
N-cadherin
cadherin 2
total:26
Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. 2010 to the paper
Abcam rabbit anti-N-cadherin antibody was used to carry out western blot analysis in order to investigate the role of forward trafficking of connexin 43 in gap junction coupling and ischemia-related cardiac arrhythmias therapy. more
NANOG
Nanog homeobox
total:6
Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma. 2010 to the paper
Abcam anti-Nanog antibody was used to perform western blot in order to study the role of LMP2A in the nasopharyngeal carcinoma progression. more
NCOA2
nuclear receptor coactivator 2
total:6
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. 2006 to the paper
BD Biosciences mouse monoclonal anti-TIF2 antibody was used in western blot (1:500) and immunohistochemistry (1:500) to assess the consequences of reducing expression of the transcription intermediary factor 2 (TIF2) coactivator on prostate cancer cell growth. more
NCoR
nuclear receptor corepressor 1
total:14
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-p300 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
NEO1
neogenin 1
total:2
Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells. 2005 to the paper
Santa Cruz Biotechnology rabbit anti-neogenin antibody was used in western blot and immunoprecipitation to study the iron accumulation in human embryonic kidney 293 cells through the interaction of hemojuvelin with neogenin. more
NEO1
neogenin 1
total:2
Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells. 2005 to the paper
Santa Cruz Biotechnology rabbit anti-neogenin antibody was used in western blot and immunoprecipitation to study the iron accumulation in human embryonic kidney 293 cells through the interaction of hemojuvelin with neogenin. more
NEUROD1
neuronal differentiation 1
total:6
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 to the paper
Santa Cruz anti-NeuroD1 antibody was used to perform western blot in order to study the roles of the fragile X mental retardation protein during the regulations of the proliferation and differentiation of adult neural stem/progenitor cells. more
neuropilin 1
total:7
Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer xenografts. 2007 to the paper
Santa Cruz Biotechnology NRP-1 antibody was used in western blot and immunohistochemistry to study the role of placenta growth factor in malignancy. more
NKX2-2
NK2 homeobox 2
total:1
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
Developmental Studies Hybridoma Bank anti-mouse Nkx2.2 antibody (1:50) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation.
NODAL
nodal growth differentiation factor
total:1
A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. 2008 to the paper
Santa Cruz Biotechnology anti-Nodal antibody was used in immunohistochemistry to identify these TGFbeta family members in human endometrium, and to determine whether they are involved in human decidualization.
NR5A2
nuclear receptor subfamily 5 group A member 2
total:2
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter by nuclear receptors liver receptor homologue-1 and small heterodimer partner: a mechanism for differential regulation of cholesterol synthesis and uptake. 2006 to the paper
Santa Cruz Biotechnology anti-LRH-1 antibody (catalog number SC-25389x) was used in human 293T cells and in ChIP assay to study the effect of nuclear receptors liver receptor homologue-1 and small heterodimer partner on 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter. more
NRAS
NRAS proto-oncogene, GTPase
total:4
Selectively oncolytic mutant of HSV-1 lyses HeLa cells mediated by Ras/RTN3. 2007 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-Ras antibody was used in western blot to study mechanism mtHSV was targeted for treating tumors but not other organs. more
Oct4
POU class 5 homeobox 1
total:21
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-OCT4 antibody was used to perform Chip in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
ONECUT1
one cut homeobox 1
total:2
Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats. 2008 to the paper
Santa Cruz Biotechnology HNF-6 antibdoy was used in western blot in order to demonstrate that continuous GH induces CYP2C12 expression by activating Erk1 and Erk2 via the GHR more
p300
E1A binding protein p300
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
p38
mitogen-activated protein kinase 14
total:189
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 to the paper
Biosource International anti-p38 antibody was used to perform western blot in order to study the effect of NFAT5 on hyperosmolar stressed human limbal epithelial cells. more
p90rsk
ribosomal protein S6 kinase A1
total:20
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Santa Cruz anti-RSK-1 antibody (1:1,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediates anti-apoptotic effects. more
PAK1
p21 (RAC1) activated kinase 1
total:29
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Epitomics rabbit monoclonal anti-Pak1 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
Pak2
p21 (RAC1) activated kinase 2
total:6
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 to the paper
Santa Cruz Biotechnology anti-PAK-2 antibody was used for western blot in order to investigate the role of PAK-2 in the regulation of anticancer drug-induced cell apoptosis. more
PAK3
p21 (RAC1) activated kinase 3
total:1
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 to the paper
Santa Cruz Biotechnology anti-PAK-3 antibody was used for western blot in order to investigate the role of PAK-2 in the regulation of anticancer drug-induced cell apoptosis.
PAK4
p21 (RAC1) activated kinase 4
total:3
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
BD Biosciences monoclonal anti-Pak4 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
PAK5
p21 (RAC1) activated kinase 5
total:1
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties. 2006 to the paper
EMD Biosciences polyclonal anti-Pak5 antibody was used in human IMR32 cells and in immunocytochemistry to study the role for nucleocytoplasmic shuttling of Pak5 in regulating its antiapoptotic properties.
PAX4
paired box 4
total:1
PAX4 enhances beta-cell differentiation of human embryonic stem cells. 2008 to the paper
Aviva PAX4 antibody (1:500) was used in western blot in order to study the role of PAX4 in the beta-cell differentiation of human embryonic stem cells
PBX1
PBX homeobox 1
total:4
Immunocytochemical detection of HoxD9 and Pbx1 homeodomain protein expression in Chinese esophageal squamous cell carcinomas. 2005 to the paper
Santa Cruz Biotechnology affinity-purified rabbit polyclonal anti-Pbx1 antibody P-20 (which recognizes a peptide mapped to the amino terminus of Pbx1 of human origin) was used in immunocytochemistry to study the expression of HoxD9 and Pbx1 homeodomain protein in Chinese esophageal squamous cell carcinomas. more
PDX-1
pancreatic and duodenal homeobox 1
total:8
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Santa Cruz Pdx1 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models more
PFN1
profilin 1
total:4
Self-assembly of filopodia-like structures on supported lipid bilayers. 2010 to the paper
Axxora anti-profilin antibody was used to carry out immunofluorescence assays in order to investigate the mechanism for how filopodia-like structures is self-assembled. more
PFN2
profilin 2
total:1
Absence of gemin5 from SMN complexes in nuclear Cajal bodies. 2007 to the paper
Dr. Glenn E Morris (RJAH Orthopaedic Hospital) monoclonal profilin II antibody (PF2A3) was used in western blot and immunocytochemistry to study the absence of gemin5 from SMN complexes in nuclear Cajal bodies
PITPNA
phosphatidylinositol transfer protein alpha
PKLR
pyruvate kinase L/R
total:1
Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes. 2009 to the paper
Abcam anti-pyruvate kinase antibody was used to perform western blot in order to study the proteomic of the keratinocytes after the treatment of low dose arsenic and ionizing radiation exposure.
PLC-gamma1
phospholipase C gamma 1
total:32
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-PLCG1 antibody was used to carry out western blot analysis and immunoprecipitation assays in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
PLXND1
plexin D1
total:1
Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice. 2010 to the paper
R&D Systems biotinylated anti-human Plexin D1 antibody was used to perform western blot and immunohistochemistry in order to study the function of sema3E-plexin D1.
PPARgamma
peroxisome proliferator activated receptor gamma
total:28
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-PPAR gamma antibody was used to carry out western blot analysis and Ch-IP assays in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
PPARGC1A
PPARG coactivator 1 alpha
total:6
Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. 2009 to the paper
Santa Cruz Biotechnology anti-PGC-1-alpha rabbit polyclonal antibody was used to carry out immunohistochemistry assays in order to investigate the functional role of Myc in mediating hypertrophic cardiomyopathy and heart failure. more
prion protein
total:17
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Chemicon anti-Prion Protein was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
PRKCQ
protein kinase C theta
total:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKCtheta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
PSD-95
discs large MAGUK scaffold protein 4
total:24
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
Thermo Scientific monoclonal anti-PSD-95 antibody was used to carry out western blot analysis and immunofluorescence assays in order to determine the atomic structure of human adenovirus. more
PTF1A
pancreas associated transcription factor 1a
Rac1
Rac family small GTPase 1
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
RAC2
Rac family small GTPase 2
total:3
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. 2009 to the paper
Proteintech Rac2 antibody was used to perform western blot in order to investigate the role of Rac2 in lymphoma progression more
radixin
total:4
Participation of ezrin in bacterial uptake by trophoblast giant cells. 2009 to the paper
EPITOMICS anti-radixin antibody was used to perform western blot in order to study the roles of ezrin in bacterial uptake by trophoblast giant cells. more
Raf-1
Raf-1 proto-oncogene, serine/threonine kinase
total:46
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. 2010 to the paper
Santa Cruz Biotechnology anti-RAF1 antibody was used to perform western blot in order to study the role of microRNA-7 in tongue squamous cell carcinoma cells. more
Ras
KRAS proto-oncogene, GTPase
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
RGMA
repulsive guidance molecule BMP co-receptor a
RhoA
ras homolog family member A
total:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoA antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
RhoB
ras homolog family member B
total:10
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
Santa Cruz Biotechnology anti-RhoB antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
RhoC
ras homolog family member C
total:5
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoC antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
ROCK1
Rho associated coiled-coil containing protein kinase 1
total:8
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 to the paper
Santa Curz anit-ROCK1 antibody was used to perform western blot to study the different roles of ROCK1 and ROCK2 in regulating keratinocyte adhesion and terminal differentiation. more
ROCK2
Rho associated coiled-coil containing protein kinase 2
total:5
RhoE Is required for keratinocyte differentiation and stratification. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-ROCKII antibody (H-85) was used in western blot to study the role for RhoE in keratinocyte differentiation and stratification more
RPS6KA2
ribosomal protein S6 kinase A2
total:9
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 to the paper
Cell Signaling anti-phosphorylated p90RSK antibody was used to perform western blot in order to study the important role of GRK4 in D3 receptor's signaling in human proximal tubule cells. more
RPS6KA3
ribosomal protein S6 kinase A3
total:9
Mitogen-activated protein kinase-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection. 2009 to the paper
Santa Cruz anti-RSK2 antibody was used to perform western blot in order to study the role of RSK2 in the cellular antiviral response. more
RPS6KA5
ribosomal protein S6 kinase A5
total:3
Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. 2009 to the paper
Santa Cruz Biotechnology MSK1 antibody was used in western blot in order to study the role of MSK1 in NF-kB activation and inflammatory diseases more
RXRalpha
retinoid X receptor alpha
total:14
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 to the paper
Santa Cruz Biotechnology polyclonal RXRs antibody was used to perform western blot in order to clarify that retinoic acid could inhibit CYP4F11 expression in human keratinocyte-derived HaCaT cells by multiple signaling pathways including RXR and JNK pathways. more
SCN1A
sodium voltage-gated channel alpha subunit 1
total:4
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. 2006 to the paper
Chemicon NaV1.1 antibody was used in western blot and immunohistochemistry to study the role of educed sodium currents in GABAergic inhibitory interneurons in Scn1a+/- heterozygotes in SMEI. more
SCN2A
sodium voltage-gated channel alpha subunit 2
total:3
A role for myosin VI in the localization of axonal proteins. 2011 to the paper
Neuromab anti-Nav1.2 antibody was used to perform immunocytochemistry in order to study the functions of myosin VI in the localization of axonal more
SCN2B
sodium voltage-gated channel beta subunit 2
total:2
Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration. 2005 to the paper
USBiological antibody which recognizes sodium channel beta 2 subunit was used in western blot to study the regulation of cell adhesion and migration by presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-Subunit. more
SCN3A
sodium voltage-gated channel alpha subunit 3
total:1
Voltage-gated sodium channels in taste bud cells. 2009 to the paper
Chemicon rabbit polyclonal antibody against SCN3A was used in immunohistochemistry to investigate the role of SCN2A, SCN3A, and SCN9A in the regulation of taste cell action potentials.
SCN5A
sodium voltage-gated channel alpha subunit 5
total:1
Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome. 2006 to the paper
Santa Cruz Biotechnology anti-hNav1.5 antibody was used in immunohistochemistry diluted 1:500 to demonstrate that both caveolin-3 and hNav1.5 colocalize at the plasma membrane of human cardiomyocytes.
SCN7A
sodium voltage-gated channel alpha subunit 7
SCN8A
sodium voltage-gated channel alpha subunit 8
total:1
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. 2006 to the paper
Chemicon anti-SCN8a antibody was used in western blot and immunohistochemistry to study the role of educed sodium currents in GABAergic inhibitory interneurons in Scn1a+/- heterozygotes in SMEI.
SCN9A
sodium voltage-gated channel alpha subunit 9
total:2
Voltage-gated sodium channels in taste bud cells. 2009 to the paper
Chemicon rabbit polyclonal antibody against SCN9A was used in immunohistochemistry to investigate the role of SCN2A, SCN3A, and SCN9A in the regulation of taste cell action potentials. more
SEMA7A
semaphorin 7A (John Milton Hagen blood group)
total:1
Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis. 2007 to the paper
R&D Systems SEMA 7A (AF1835) antibody was used in western blot to study the role of semaphorin 7A in TGF-beta1-induced pulmonary fibrosis
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1
total:1
Study of the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma. 2007 to the paper
Santa Cruze SH3GL2 goat polyclonal antibody was used in western blot to study the SH3-study the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma.
SHP-2
protein tyrosine phosphatase non-receptor type 11
total:34
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-Shp2 antibody was used to perform western blot in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
Smad2
SMAD family member 2
total:74
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. 2010 to the paper
Cell Signaling anti-Smad2 was used to perform western blot in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia more
Smad3
SMAD family member 3
total:51
Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation. 2009 to the paper
Zymed Smad3 polyclonal antibody was used in western blot in order to investigate the role of BMP9 signalling via ALK2/Smad1/Smad4 pathway in ovarian cancer. more
Smad4
SMAD family member 4
total:21
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 to the paper
Santa Cruz rabbit anti-Smad4(H-552; 1:1,000) antibody was used to perform western blot in order to study the dynamical regulation of TGF-beta signaling during late lung development in the human and mouse. more
SMRT
nuclear receptor corepressor 2
total:11
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Affinity Bioreagents anti-SMRT antibody was used to perform western blot in order to show that IRF5 mediates the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
Sos
SOS Ras/Rac guanine nucleotide exchange factor 1
total:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Santa Cruz rabbit Sos-1 antibody was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation. more
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2
total:1
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis. 2005 to the paper
BD Biosciences anti-SOS-2 antibody was used in western blot to study the role of AIF in nuclear phenotype and DNA degradation during apoptosis
SOX2
SRY-box transcription factor 2
total:8
Loss of FGF-dependent mesoderm identity and rise of endogenous retinoid signalling determine cessation of body axis elongation. 2012 to the paper
Immune Systems goat anti-Sox2 antibody was used to perform immunocytochemistry in order to study the mechanism that underlied termination of body axis elongation in embryos. more
SPTA1
spectrin alpha, erythrocytic 1
total:6
Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. 2005 to the paper
Chemicon anti-spectrin antibody was used in western blot in order to investigate the molecular mechanism of beta-amyloid induced significant decrease of dynamin1. more
SPTA1
spectrin alpha, erythrocytic 1
total:6
Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. 2005 to the paper
Chemicon anti-spectrin antibody was used in western blot in order to investigate the molecular mechanism of beta-amyloid induced significant decrease of dynamin1. more
SPTBN4
spectrin beta, non-erythrocytic 4
SPTBN4
spectrin beta, non-erythrocytic 4
Src
SRC proto-oncogene, non-receptor tyrosine kinase
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
SRC-1
nuclear receptor coactivator 1
total:12
The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors. 2009 to the paper
Affinity BioReagents anti-SRC1 antibody was used in immunoprecipitation in order to investigate the cooperation between thyroid hormone receptor beta2 and p160 coactivator PAS-B through multiple contact surfaces. more
SRC3
nuclear receptor coactivator 3
total:9
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-SRC-3 antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
total:1
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-srGAP1 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation.
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
total:1
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-srGAP1 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation.
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAT3
signal transducer and activator of transcription 3
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
STX
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
TAG-1
contactin 2
total:8
Human T-cell leukemia virus type 1 oncoprotein tax represses ZNF268 expression through the cAMP-responsive element-binding protein/activating transcription factor pathway. 2008 to the paper
Epitomics anti-Tax monoclonal antibody was used to perform EMSA in order to show that ZNF268 expression can be inhibited by HTLV-1 Tax. more
Talin
talin 1
total:10
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Serotec anti-talin antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
TCF3
transcription factor 3
total:7
Nucleoprotein structure of the CD4 locus: implications for the mechanisms underlying CD4 regulation during T cell development. 2008 to the paper
Santa Cruz Biotechnology E2A antibody was used in ChIP assays in order to study the molecular basis of CD4 regulation and provide a conceptual framework for understanding how the same regulatory elements can mediate both reversible and irreversible CD4 regulation more
TRIO
trio Rho guanine nucleotide exchange factor
TRPC1
transient receptor potential cation channel subfamily C member 1
total:5
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. 2005 to the paper
Alomone Labs anti-TRPC1 antibody was used in western blot to study the role of endogenous TRPC6 channels in Ca2+ signal generation. more
TRPC3
transient receptor potential cation channel subfamily C member 3
total:6
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC3 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
TRPC4
transient receptor potential cation channel subfamily C member 4
total:7
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC4 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
TRPC5
transient receptor potential cation channel subfamily C member 5
total:4
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC5 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
TRPC6
transient receptor potential cation channel subfamily C member 6
total:7
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC6 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
TRPC7
transient receptor potential cation channel subfamily C member 7
total:1
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. 2005 to the paper
Santa Cruz anti-TRPC7 antibody was used in western blot to study the role of endogenous TRPC6 channels in Ca2+ signal generation.
UNC5H2
unc-5 netrin receptor B
total:1
Unc5B associates with LARG to mediate the action of repulsive guidance molecule. 2009 to the paper
R&D Systems Unc5B antibody was used for western blot in order to investigate the role of Unc5B and LARG in the regulation of repulsive guidance molecule.
VASP
vasodilator stimulated phosphoprotein
total:10
Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function. 2009 to the paper
Chemicon International rabbit polyclonal anti-VASP antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the roles of ADMA and DDAH in the regulation of pulmonary endothelial barrier function. more
WASL
WASP like actin nucleation promoting factor
total:2
The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal Cdc42 antibody was used in western blot and immunoprecipitation to study the role of the adapter protein CrkII in the regulation of N-WASp and Cdc42 activation. more
ZSCAN10
zinc finger and SCAN domain containing 10