DARPP-32 events
gene
reagent
sample publication
sample review
total:8
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 to the paper
Santa Cruz Biotechnology anti-Cdk5 (SC-173), Cdk5-pTyr-15 (SC-12918), and Cdk5-pSer-159 (SC-12919) antibodies were used to perform western blot in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration. more
total:3
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Abcam anti-PDE4 antibody was used in western blot in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
total:1
Short-term or long-term treatments with a phosphodiesterase-4 (PDE4) inhibitor result in opposing agonist-induced Ca(2+) responses in endothelial cells. 2008 to the paper
FabGennix anti-PDE4C antibody was used in western blot to study the effects of longer term pre-treatment with a specific inhibitor of phosphodiesterase-4 (PDE4), on [Ca2+]i, cAMP levels, and PDE activity and expression in HUVEC.
total:1
Expression of the cAMP-phosphodiesterase PDE4D isoforms and age-related changes in follicle-stimulating hormone-stimulated PDE4 activities in immature rat sertoli cells. 2007 to the paper
Santa Cruz Biotechnology anti-PDE4D antibody was used in western blot to evaluate the cAMP response to FSH and the FSH-stimulated PDE activities in proliferating.
total:19
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. 2008 to the paper
Santa Cruz anti-PP1alpha was used to perform western blot in order to show that SRC-3/AIB1 coactivator function and turnover is regulated by essential phosphatases and a phospho-degron of SRC-3/AIB1 is primary determinants of its turnover. more
total:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2Ac antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:3
Brain-specific regulator of G-protein signaling 9-2 selectively interacts with alpha-actinin-2 to regulate calcium-dependent inactivation of NMDA receptors. 2006 to the paper
Santa Cruz Biotechnology anti-dopamine- and cAMP-regulated phosphoprotein of 32 kDa (DARPP-32) antibody was used in immunoprecipitation to identify the interaction between RGS9-2 and alpha-actinin-2. more
total:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate polyclonal anti-PP2A-A antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 to the paper
Sigma-Aldrich polyclonal antibody to the PP2APR65 subunit was used to perform western blot in order to investigate the functions of salt-inducible kinase-1. more
total:4
Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. 2009 to the paper
Sigma-Aldrich anti-calcineurin A antibody was used in western blot in order to deduce that calcineurin activity and apoptosis of leukemic lymphocytes can be modulated by GC-mediated upregulation of RCAN1-1. more
total:2
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. 2005 to the paper
Chemicon rabbit anti-calcineurin antibody was used in immunohistochemistry to study the mechanisms that trigger astrocyte activation. more
total:3
Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. 2006 to the paper
Sigma CnB1 antibody was used in western blot to demonstrate direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. more
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
total:9
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIalpha was used in immunohistochemistry to detect the PKA subunit RIalpha in human adrenal samples more
total:9
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Santa Cruz Biotechnology anti-PKA RII antibody was used in immunoprecipitation in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
total:3
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIIbeta was used in immunohistochemistry to detect the PKA subunit RIIbeta in human adrenal samples more