Complement cascade
gene
reagent
sample publication
sample review
C1QA
complement C1q A chain
total:1
Analysis of binding sites in human C-reactive protein for Fc{gamma}RI, Fc{gamma}RIIA, and C1q by site-directed mutagenesis. 2005 to the paper
Quidel mouse monoclonal C1q antibody was used in ELISA to study various binding sites in human C-reactive protein
C3
complement C3
total:12
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. 2011 to the paper
AbD serotec goat-anti-Human-C3 was used to perform ELISA in order to show that HIV glycan coat could be recognized by PGT antibody to neutralize HIV. more
C4A
complement C4A (Rodgers blood group)
total:2
Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells. 2009 to the paper
Chemicon C4 monoclonal antibody was used in western blot to study the role of TLS DNA polymerases eta and kappa in the regulation of naturally occurring DNA structures in human cancer cells. more
C4B_2
complement component 4B (Chido blood group), copy 2
C5
complement C5
total:1
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. 2005 to the paper
Quidel mouse monoclonal antibody against C5b-9 was used in ELISA to study the association of the extracellular matrix and inflammation
C9
complement C9
total:2
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
S.Piddelsden anti C9neo antibody (1:2000) was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
CD46
CD46 molecule
total:8
CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells. 2010 to the paper
Hycult-Biotechnologies anti-CD46 mouse monoclonal antibody was used to perform western blot and flow cytometry in order to study the function of CD147/EMMPRIN as a receptor for measles virus on epithelial cells. more
CD55
CD55 molecule (Cromer blood group)
total:14
The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium. 2008 to the paper
Serotec monoclonal anti-CD55 antibody (67) was used in immunohistochemistry to determine whether the heterogeneous clinical response to tumour necrosis factor (TNF) alpha blocking therapy in rheumatoid arthritis (RA) can be predicted by TNFalpha expression in the synovium before initiation of treatment. more
CD59
CD59 molecule (CD59 blood group)
total:10
Activity after site-directed mutagenesis of CD59 on complement-mediated cytolysis. 2008 to the paper
Santa Cruz Biotechnology goat anti-human CD59 polyclonal antibody(Catalog #, sc-7077) was used to perform Enzyme-linked immunosorbent assays in order to demonstrate that residue W40 site of CD59 is important to its anti-complement activity. more
CFD
complement factor D
total:1
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-Adipsin antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis.
CR1
complement C3b/C4b receptor 1 (Knops blood group)
total:2
Mesenchymal stem cell-mediated functional tooth regeneration in swine. 2006 to the paper
Pharmingen/BD Bioscience R-PE conjugated monoclonal anti-human CD35 antibody was used in human mesenchymal stem cell and in flow cytometry to study the role for mesenchymal stem cell in tooth regeneration in swine. more
factor H
complement factor H
total:12
Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. 2010 to the paper
AbD Serotec mouse monoclonal anti-human FH was used to perform flow cytometry in order to show that function of factor H is defective in patients with systemic sclerosis and sclerodermatous GVHD. more
MBL2
mannose binding lectin 2
total:4
High prevalence of mannose-binding lectin (MBL) deficiency in premature neonates. 2006 to the paper
Sanquin biotinylated mouse-anti-MBL IgG 5E12 (10 ug/ml) was used in ELISA assay as the detection antibody to measure MBL in plasma to study the high prevalence of mannose-binding lectin (MBL) deficiency in premature neonates more
vitronectin
total:4
The effect of RGD peptides on osseointegration of hydroxyapatite biomaterials. 2008 to the paper
Santa Cruz vitronectin antibody was used in western blot in order to study the effect of RGD peptides on osseointegration of hydroxyapatite biomaterials more