Collagen degradation
gene
reagent
sample publication
sample review
ADAM10
ADAM metallopeptidase domain 10
total:10
S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10. 2009 to the paper
Chemicon ADAM-10 antibody was used for western blot in order to indentify new biomarker of Alzheimer's disease. more
ADAM17
ADAM metallopeptidase domain 17
total:13
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. 2008 to the paper
Santa Cruz Biotechnology anti-TACE antibody was used to perform Western Blot in order to show that TACE has a inhibitory role in EGFR axis in colorectal cancer. more
ADAM9
ADAM metallopeptidase domain 9
total:6
Human parainfluenza virus type 2 (HPIV2) induced host ADAM8 expression in human salivary adenocarcinoma cell line (HSY) during cell fusion. 2009 to the paper
Triple Point Biologics polyclonal rabbit anti-human ADAM9 antibody was used in immunocytochemistry to investigate expression of ADAMs of host cell origin during cell-cell fusion induced by human parainfluenza virus type 2 more
cathepsin B
total:14
Acid sphingomyelinase activity triggers microparticle release from glial cells. 2009 to the paper
Chemicon rabbit polyclonal anti-Cathepsin B Ab (1:200) was used in western blot in order to study the activation of acid sphingomyelinase in microparticle release from glial cells. more
cathepsin D
total:13
Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. 2009 to the paper
Santa Cruz Biotechnology primary anti-cathepsin D (H-75) was used to detect endogenous lysosomal and ER proteins by immunohistochemistry method in order to study the preferentially expressed characterization of the arylsulfatase I (ARSI) gene. more
cathepsin L
total:8
Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function. 2008 to the paper
Calbiochem of EMD Bioscience Inc. anti-cathepsin L antibody was used in western blot to study the effect of the role for Anaplasma phagocytophilum in increasing cathepsin L activity on neutrophil function. more
COL9A1
collagen type IX alpha 1 chain
total:2
Alteration of medial-edge epithelium cell adhesion in two Tgf-beta3 null mouse strains. 2008 to the paper
Developmental Studies Hybridoma Bank 1:50 monoclonal mouse IgG anti-sheep collagen IX antibody was used in immunohistochemistry in order to study the role of growth factor TGF-b3 in palatal shelf adhesion more
ELANE
elastase, neutrophil expressed
total:11
Mycobacterial disease and impaired IFN-? immunity in humans with inherited ISG15 deficiency. 2012 to the paper
Abcam anti-elastase antibody was used to perform western blot and immunocytochemistry in order to show that ISG15 deletion in humans impairs IFN-gamma immunity and results in mycobacterial disease susceptibility. more
endostatin
collagen type XVIII alpha 1 chain
total:4
Reduction of endogenous angiogenesis inhibitors in Bruch's membrane of the submacular region in eyes with age-related macular degeneration. 2008 to the paper
R&D Systems anti-endostatin antibody was used to perform immunohistochemistry in order to study the level of angiogenesis inhibitors in eyes with age-related macular degeneration. more
MMP-1
matrix metallopeptidase 1
total:13
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 to the paper
Calbiochem anti-MMP-1 monoclonal antibody was used to perform western blot in order to study the role of CD147 promoted myofibroblast differentiation in tissue remodeling. more
MMP-1
matrix metallopeptidase 1
total:13
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 to the paper
Calbiochem anti-MMP-1 monoclonal antibody was used to perform western blot in order to study the role of CD147 promoted myofibroblast differentiation in tissue remodeling. more
MMP-1
matrix metallopeptidase 1
total:13
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 to the paper
Calbiochem anti-MMP-1 monoclonal antibody was used to perform western blot in order to study the role of CD147 promoted myofibroblast differentiation in tissue remodeling. more
MMP-2
matrix metallopeptidase 2
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
MMP-2
matrix metallopeptidase 2
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
MMP-2
matrix metallopeptidase 2
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
MMP-3
matrix metallopeptidase 3
total:8
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-3 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
MMP-3
matrix metallopeptidase 3
total:8
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-3 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
MMP-7
matrix metallopeptidase 7
total:9
Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma. 2010 to the paper
Santa Cruz Biotechnology anti-MMP7 antibody was used in immunohistochemistry to investigate the function of UPK1A in esophageal squamous cell carcinoma. more
MMP-8
matrix metallopeptidase 8
total:6
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
Chemicon MMP-8 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more
MMP-9
matrix metallopeptidase 9
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
MMP-9
matrix metallopeptidase 9
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
MMP10
matrix metallopeptidase 10
total:5
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
R&D Systems anti-MMP-10 antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
MMP12
matrix metallopeptidase 12
total:4
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
R/D Systems MMP-12 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more
MMP13
matrix metallopeptidase 13
total:7
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-13 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
MMP13
matrix metallopeptidase 13
total:7
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-13 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
MMP15
matrix metallopeptidase 15
total:3
Opposing effects of interferon-alpha and interferon-gamma on the expression of major histocompatibility complex class I chain-related A in tumors. 2008 to the paper
Santa Cruz Biotechnology anti-MT2-MMP antibody was used to perform western blot in order to study the differential effects of IFN-alpha and IFN-gamma on tumor cells. more
MMP19
matrix metallopeptidase 19
total:4
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
Triple Point Biologics MMP-19 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more
MT1-MMP
matrix metallopeptidase 14
total:15
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 to the paper
Acris anti-MMP14(113-5B7) antibody was used to perform immunohistochemistry in order to study the expression of cytokeratin 7 and 19 are related with genomic stability and favorable prognosis in clear cell renal cell cancer. more
stromelysin 3
matrix metallopeptidase 11
total:4
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
Chemicon MMP-11 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more