Circadian Clock
gene
reagent
sample publication
sample review
CKI epsilon
casein kinase 1 epsilon
total:5
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 to the paper
Abgent anti-CKI epsilon was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction more
ARNTL
aryl hydrocarbon receptor nuclear translocator like
total:1
CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor alpha (PPARalpha) in mice. 2005 to the paper
Santa Cruz Biotechnology BMAL1 (internal region) antibody was used in EMSA to study circadian transactivation of peroxisome-proliferator-activated receptor a (PPARa) in mice
AVP
arginine vasopressin
total:1
Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration. 2007 to the paper
Santa Cruz Biotechnology type I ADH antibody was used in western blot to study the role of alcohol and aldehyde dehydrogenase activities in rat liver regeneration.
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
total:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Zymed Laboratories mouse anti-beta TRCP antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
CLOCK
clock circadian regulator
total:2
Identification of small molecule activators of cryptochrome. 2012 to the paper
Affinity BioReagents anti-CLOCK was used to perform western blot in order to show that cryptochrome could be studied by specific small molecule activators. more
CSNK1D
casein kinase 1 delta
total:1
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 to the paper
Santa Cruz anti-CKI delta was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction
Cul1
cullin 1
total:12
Mediator acts upstream of the transcriptional activator Gal4. 2012 to the paper
Abcam anti-Cul1 mouse monoclonal antibody was used to perform immunoprecipitation in order to study how the Mediator initiated Gal4 transcription. more
FBXL3
F-box and leucine rich repeat protein 3
HDAC3
histone deacetylase 3
total:21
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 to the paper
Santa Cruz Biotechnology anti-HDAC3 antibody was used to perform western blot assay in order to identify novel histone deacetylase complexes that promote expansions of trinucleotide repeats. more
NCoR
nuclear receptor corepressor 1
total:14
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-p300 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
NPAS2
neuronal PAS domain protein 2
total:1
The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response. 2008 to the paper
Santa Cruz rabbit polyclonal anti-NPAS2 antibody was used to perform western blot in order to show that circadian gene NPAS2 is a putative tumor suppressor involved in DNA damage response.
NR1D1
nuclear receptor subfamily 1 group D member 1
total:1
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. 2009 to the paper
Cell Signaling anti-REVERB alpha antibody was used to perform western blot in order to study the mechanism of the AMPK's regulation towards the circadian clock.
p300
E1A binding protein p300
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
PAI-1
serpin family E member 1
total:16
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 to the paper
Novus Biologicals goat anti-human plasminogen antibody was used to perform ELISA in order to investigate the interaction between leptospiral endostatin-like protein A and human plasminogen. more
PPAR
peroxisome proliferator activated receptor alpha
total:9
Integration of microRNA miR-122 in hepatic circadian gene expression. 2009 to the paper
Abcam rabbit polyclonal antibody PPAR was used for immunoprecipitation in order to study the circadian gene expression of integration of microRNA miR-122 in hepatic. more
PPARGC1A
PPARG coactivator 1 alpha
total:6
Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. 2009 to the paper
Santa Cruz Biotechnology anti-PGC-1-alpha rabbit polyclonal antibody was used to carry out immunohistochemistry assays in order to investigate the functional role of Myc in mediating hypertrophic cardiomyopathy and heart failure. more
RPS27A
ribosomal protein S27a
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
Skp1
S-phase kinase associated protein 1
total:8
APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. 2009 to the paper
Zymed mouse monoclonal anti-Skp1 antibody was used in western blot to investigate the regulation of Cdc20 stability during SAC activation in mammalian cells and explore the contribution of spindle checkpoint proteins to Cdc20 stability. more
SREBP-1
sterol regulatory element binding transcription factor 1
total:11
Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 to the paper
NeoMarkers monoclonal SREBP-1 antibody was used in western blot in order to study the mechanism by which the activation of Wnt/beta-catenin signaling in skeletal muscle cells can improve insulin sensitivity. more
UBC
ubiquitin C
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
ubiquitin
ubiquitin B
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
visfatin
nicotinamide phosphoribosyltransferase
total:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 to the paper
Bethyl Laboratories NAMPT antibody was used for western blot in order to investigate the role of DBC1 in the regulation of SIRT1 activity and high-fat diet induced liver steatosis in mice.