Chromatin modifying enzymes
gene
reagent
sample publication
sample review
total:2
Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism. 2008 to the paper
Proteintech Group anti-BAF53a antibody used to perform immunoprecipitation in order to study the association between the SWI/SNF chromatin-remodeling complexes and the hepatic lipid metabolism. more
total:2
Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism. 2008 to the paper
Proteintech Group anti-BAF53a antibody used to perform immunoprecipitation in order to study the association between the SWI/SNF chromatin-remodeling complexes and the hepatic lipid metabolism. more
total:20
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB2 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:1
PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins. 2006 to the paper
Affinity BioReagents anti-ATXN7 antibody was used in immunocytochemistry in order to investigate the mechanism of how promyelocytic leukemia protein (PML) clastosomes prevent polyglutamine and mutant ataxin-7 aggregation in the nucleus.
total:149
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-beta-actin was used to perform western blot in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:149
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-beta-actin was used to perform western blot in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
total:2
Identification of small molecule activators of cryptochrome. 2012 to the paper
Affinity BioReagents anti-CLOCK was used to perform western blot in order to show that cryptochrome could be studied by specific small molecule activators. more
total:1
p400 is required for E1A to promote apoptosis. 2005 to the paper
Santa Cruz Biotechnology anti-E1A antibody was used in western blot and immunoprecipitation to study that p400 is required for E1A to promote apoptosis.
total:1
p400 is required for E1A to promote apoptosis. 2005 to the paper
Santa Cruz Biotechnology anti-E1A antibody was used in western blot and immunoprecipitation to study that p400 is required for E1A to promote apoptosis.
total:32
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-H3K4 antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
total:11
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Active Motif anti-H4K12Ac antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:3
Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growth.. 2008 to the paper
Santa Cruz Biotechnology anti-vp16 antibody was used for western blot in order to investigate the role of Chk2 in the regulation of HSV-1 ICP0-mediated G2/M arrest and virus growth more
total:1
Testis/sperm-specific histone 2B in the sperm of donors and subfertile patients: variability and relation to chromatin packaging. 2007 to the paper
Chemicon International TSH2B antibody was used in western blot to assesse the association of TSH2B with chromatin compaction status.
total:1
p53 chromatin epigenetic domain organization and p53 transcription. 2009 to the paper
Abcam anti-histone H2Bantibody was used to perform immunoprecipitation in order to demonstrate that physical barrier due to the folding of chromatin in domain II can give rise to the depletion of RNA polymerase II.
total:5
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Abcam anti-Histone 3, anti-H3 K9Me, and anti-H3 S10ph antibodies were used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:6
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Abcam anti-H2A antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:10
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-H2B antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:1
Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP. 2009 to the paper
Santa Cruz Biotech anti-carboxyl terminus of human IKAP antibody (1:3,000) was used to perform western blot in order to study the rescuing function of human IKBKAP in the embryonic lethality resulting from mouse Ikbkap ablation.
total:3
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. 2008 to the paper
Abcam anti-ING4 antibody was used to perform western blot in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters. more
total:2
A phosphorylation-acetylation switch regulates STAT1 signaling. 2009 to the paper
Santa Cruz Biotechnology GCN5 antibody was used for western blot in order to investigate the role of phosphorylation-acetylation switch in the regulation of STAT1 signaling. more
total:1
MOZ-TIF2 repression of nuclear receptor-mediated transcription requires multiple domains in MOZ and in the CID domain of TIF2. 2007 to the paper
Santa Cruz Biotechnology MOZ antibody was used in immunocytochemistry to study the effection of MOZ-TIF2 fusion protein on nuclear receptor signaling.
total:1
Characterizing the cancer genome in lung adenocarcinoma. 2007 to the paper
Proteintech Group anti-MBIP polyclonal antibody was used to perform western blot in order to study the chromosome copy-number alterations in primary lung adenocarcinomas.
total:3
Phosphofructokinase 1 glycosylation regulates cell growth and metabolism. 2012 to the paper
Affinity BioReagents anti-O-GlcNAc was used at 1:1000 to perform western blot in order to show that cancer cell growth was regulated by PFK1 glycosylation more
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:15
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-PCAF antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:6
CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene. 2006 to the paper
Abcam RbAp46 antibody was used in immunoprecipitation to study the molecular mechanism (s) by which CTIP2 contributes to T cell development and axonal. more
total:2
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization. 2008 to the paper
Proteintech rabbit anti-RUVBL1 antibody was used for western blot in order to investigate the role of ILK in the regulation of mitotic spindle organization. more
total:2
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization. 2008 to the paper
Proteintech rabbit anti-RUVBL1 antibody was used for western blot in order to investigate the role of ILK in the regulation of mitotic spindle organization. more
total:1
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Affinity Bioreagents anti-mSin3a antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs.
total:2
SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation. 2009 to the paper
Upstate Biochemistry amti-RNA polymerase II antibody was used for immunoprecipitation in order to indicate that SUMOylation is mediated through reduced CDK7-induced phosphorylation of SF-1. more
total:2
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 to the paper
Irwin Davidson TAF12 antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires. more
total:1
Core promoter binding by histone-like TAF complexes. 2005 to the paper
Santa Cruz Biotechnology anti-TAF9 antibody was used in western blot, immunoprecipitation, and EMSA to study histone-like TAF complexes
total:14
PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis. 2009 to the paper
Santa Cruz Biotechnology anti-Tip60 antibody was used in western blot in order to explain that PDCD5 can maintain the histone acetyltransferase activity of the Tip60 protein and promote DNA damage-induced apoptosis as a Tip60 coactivator. more
total:14
PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis. 2009 to the paper
Santa Cruz Biotechnology anti-Tip60 antibody was used in western blot in order to explain that PDCD5 can maintain the histone acetyltransferase activity of the Tip60 protein and promote DNA damage-induced apoptosis as a Tip60 coactivator. more
total:3
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 to the paper
Santa Cruz anti-TRRAP antibody was used in western blot to study the role for the STAGA subunit ADA2b in regulating human GCN5 catalysis. more
total:3
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 to the paper
Santa Cruz anti-TRRAP antibody was used in western blot to study the role for the STAGA subunit ADA2b in regulating human GCN5 catalysis. more
total:1
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol. 2010 to the paper
Abcam anti-USP22 antibody was used to perform western blot in order to study the modulation of intracellular F. tularensis phagosome biogenesis and proliferation.
total:2
Long noncoding RNA as modular scaffold of histone modification complexes. 2010 to the paper
Bethyl rabbit anti-WDR5 antibody was used to carry out RNA immunoprecipitation assays in order to investigate the role for long intergenic noncoding RNAs as scaffolds to regulate histone modification complexes and gene expression. more