Cell-cell junction organization
gene
reagent
sample publication
sample review
AF6
afadin, adherens junction formation factor
total:6
AF6 negatively regulates Rap1-induced cell adhesion. 2005 to the paper
Transduction Laboratories monoclonal anti-AF6 antibody was used in western blot to detect AF6 in Jurkat cells stably expressing Epac (HB6 cells) cotransfected with empty vector or HA-AF6. more
alpha-catenin
catenin alpha 1
total:24
Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma. 2010 to the paper
BD Biosciences anti-a-catenin antibody was used to perform western blot in order to study the role of LMP2A in the nasopharyngeal carcinoma progression. more
beta-catenin
catenin beta 1
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
CDH15
cadherin 15
total:1
Long-term survival of transplanted stem cells in immunocompetent mice with muscular dystrophy. 2008 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-M-cadherin antibody was used in flow cytometry at 1:50 in order to study the role of duchenne muscular dystrophy in the long-term survival of transplanted stem Cells
CDH6
cadherin 6
total:1
Cadherin-6 function in zebrafish retinal development. 2008 to the paper
Covance Research Products anti-cadherin-6 antibody was used in western blot at 1:500 and immunohistochemistry at 1:300 in order to study the role of Cadherin-6 in the formation of the retina
claudin-1
claudin 1
total:13
Protein kinase A-dependent step(s) in hepatitis C virus entry and infectivity. 2008 to the paper
Novus anti-CLDN1 antibody 1C5-D9 was used in immunocytochemistry to study the role for protein kinase signaling in HCV infection more
CLDN11
claudin 11
total:2
MMP-28 as a regulator of myelination. 2008 to the paper
Santa Cruz anti-Claudin-11 antibody was used in immunocytochemistry to study the role for MMP-28 in myelination. more
CLDN19
claudin 19
total:1
Renal localization and function of the tight junction protein, claudin-19. 2007 to the paper
Zymed polyclonal claudin-19 antiserum was used in western blot (1:1,000) and immunohistochemistry (1:100) to study the distribution and possible functional role of claudin-19 in the renal tubule.
CLDN3
claudin 3
total:7
Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection. 2010 to the paper
Labvision rabbit anti-Claudin-3 (clone WN1 222-5) polyclonal antibody was used to perform immunohistochemistry in order to shown that in the absence of SIV infection, PTM have damage to their gastrointestinal tract and increased basal levels of microbial translocation and immune activation. more
CLDN4
claudin 4
total:6
Phosphorylation of claudin-3 at threonine 192 by cAMP-dependent protein kinase regulates tight junction barrier function in ovarian cancer cells. 2005 to the paper
Zymed Laboratories mouse anti-claudin-4 monoclonal antibody was used in western blot and immunoprecipitation to study that phosphorylation of claudin-3 at threonine 192 by cAMP-dependent protein kinase regulates tight junction carrier function in ovarian cancer cells. more
CLDN5
claudin 5
total:3
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Zymed Laboratories mouse anti-claudin-5 antibody was used in western blot and immunohistochemistry to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
CLDN7
claudin 7
total:5
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
Invitrogen anti-claudin-1 antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
CRB3
crumbs cell polarity complex component 3
E-cadherin
cadherin 1
total:129
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Invitrogen rat anti-E-Cadherin (ECCD-2; 13-1900) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
gamma-catenin
junction plakoglobin
total:17
The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells. 2010 to the paper
BD Biosciences anti-plakoglobin antibody was used to carry out western blot and immunostaining assays in order to investigate the role of the T-box transcription factor Brachyury in tumor cells epithelial-mesenchymal transition and and tumor progression. more
PATJ
PATJ crumbs cell polarity complex component
MPP5
membrane palmitoylated protein 5
total:1
Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. 2005 to the paper
Upstate Biotechnologies Pals1 antibody was used in western blot to study the role of Par-3 in epithelial cell polarization in mammals.
N-cadherin
cadherin 2
total:26
Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. 2010 to the paper
Abcam rabbit anti-N-cadherin antibody was used to carry out western blot analysis in order to investigate the role of forward trafficking of connexin 43 in gap junction coupling and ischemia-related cardiac arrhythmias therapy. more
nectin 4
nectin cell adhesion molecule 4
total:2
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
R&D Systems mouse anti-human PVRL4 IgG2B was used to perform cell culture in order to investigate the role of PVRL4 in tumor progression. more
p120ctn
catenin delta 1
total:23
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-p120-catenin antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
PARD6G
par-6 family cell polarity regulator gamma
NECTIN1
nectin cell adhesion molecule 1
total:3
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
R&D Systems goat anti-human PVRL1 antibody was used to perform cell culture and western blot in order to investigate the role of PVRL4 in tumor progression. more
NECTIN3
nectin cell adhesion molecule 3
total:1
A double mutation in glycoprotein gB compensates for ineffective gD-dependent initiation of herpes simplex virus type 1 infection. 2010 to the paper
R&D anti-nectin-3 monoclonal antibody was used to pretreat CHO-K1 cells in vitro to investigate the compensation by mutated-gB for initiation of HSV-1 Infection.
T cadherin
cadherin 13
total:5
Association of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5A. 2008 to the paper
Calbiochem anti-pan-cadherin antibody was used in western blot in order to identify NS5A-associated target molecules more
TSLL1
cell adhesion molecule 3
total:1
Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule. 2005 to the paper
Immunex antibody anti-hNecl1 (M170) was used in flow cytometry to identify a subset of T-cell zone dendritic cells by nectin-like protein 2
VE cadherin
cadherin 5
total:19
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. 2009 to the paper
eBioscience anti-CD144 antibody was used in immunohistochemistry in order to demonstrate that vasculogenesis in human MM may develop from tumoral production of pleiotrophin, which induces the transdifferentiation of monocytes into VECs. more