Cell Cycle
gene
reagent
sample publication
sample review
total:5
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 to the paper
Abgent anti-CKI epsilon was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction more
total:5
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Santa Cruz Biotechnology anti-14-3-3epsilon antibody (1:2000) was used in western blot to study the effects of curcumin on the expression of peroxisome proliferator-activated receptor delta (PPARdelta) and related genes in HT-29 cells. more
total:3
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3gamma antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
total:23
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Rockland anti-pT232 Aurora B was used to perform immunocytochemistry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:19
Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2. 2009 to the paper
GeneTex mouse anti-tubulin antibody was used in western blot to study the role for the binding and interaction of ferroportin with Jak2 in hepcidin-induced internalization of ferroportin. more
total:1
Meningiomas exhibit loss of heterozygosity of the APC gene. 2008 to the paper
Calbiochem monoclonal mouse anti-human APC-1 antibody (1:50) was used to perform immunohistochemistry in order to study the adenomatous polyposis coli (APC) gene's loss of heterozygosity in meningiomas.
total:1
Downregulation of the anaphase-promoting complex (APC)7 in invasive ductal carcinomas of the breast and its clinicopathologic relationships. 2005 to the paper
Santa Cruz Biotechnology anti-human APC7 antibody was used in western blot and immunohistochemistry to study the clinical significance and the involvement of APC in tumorigenesis.
total:50
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Millipore anti-phospho-ATM-S1981 antibody was used to perform immunofluorescence assay in order to detect the requirment of RSF1 for the recruitment of CENPS/MHF1, CENPX/MHF2, FANCD2, and FANCI to IRIF. more
total:24
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Santa Cruz human ATR antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:1
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 to the paper
R&D anti-ATRIP monoclonal antibody was used to perform immunofluorescence and western blot in order to study the interactions of ATR and ATRIP in gene expression and production of virus during HSV-1. infection.
total:15
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Cell Signaling Technology anti-AURKA monoclonal antibody was used to study its relation between RHAMM by immunobloting. more
total:1
Binding of barrier to autointegration factor (BAF) to histone H3 and selected linker histones including H1.1. 2005 to the paper
Dr Roc o Montes de Oca anti-BAF antibody was used in immynoprecipitation to study the role of binding of barrier to autointegration factor (BAF) and selected linker histones.
total:10
Phosphorylation-dependent interactions of BLM and 53BP1 are required for their anti-recombinogenic roles during homologous recombination. 2008 to the paper
Novus anti-BLM antibody (NB100-161) was used to perform immunoprecipitation and western blot in order to study the formation of BLM-53BP1-RAD51 complex. more
total:42
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Calbiochem anti-BRCA1 monoclonal antibody was used to perform immunoprecipitation in order to study the function of apicobasal polarity and regulation of stem cell in breast cancer more
total:10
FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. 2010 to the paper
EMD anti-BRCA2 antibody was used to carry out immunofluorescence assays in order to investigate the role for FAN1 in promoting DNA interstrand cross-link repair by mono-ubiquitylating FANCI-FANCD2 complex. more
total:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Zymed Laboratories mouse anti-beta TRCP antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
total:2
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Chemicon mouse monoclonal anti-Bub1 antibody was used to carry out western blot analysis in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:6
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. 2010 to the paper
BD Transduction Laboratories anti-BUB1B antibody was used in western blot in order to investigate the different expression levels of spindle proteins in the testicular germ cell tumors. more
total:2
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
BD Transduction Laboratories monoclonal anti-BUB3 antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
total:14
CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. 2009 to the paper
Santa Cruz Biotechnology anti-cyclin A antibody was used in western blot in order to study the reguation of the expression of Ect2, MgcRacGAP, and MKLP1 during cell cycle progression more
total:1
Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control. 2007 to the paper
Santa Cruz Biotechnology cyclin B2 antibody was used in western blot to demonstrate the opposing roles of distinct mammalian SWI/SNF chromatin remodeling complexes in cell-cycle control.
total:4
Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes. 2013 to the paper
Epitomics anti-CYCE2 antibody was used to perform western blot assay in order to investigate the interaction of CYCE2 with SCML2 more
total:3
Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. 2005 to the paper
Santa Cruz Biotechnology cyclin H antibody was used in western blot to study the role of Dmp1 in Ras-Raf-Arf signaling. more
total:1
Regulation of Spo12 phosphorylation and its essential role in the FEAR network. 2009 to the paper
Santa Cruz goat anti-Cdc14 antibody (1:300 dilution) was used to perform immunofluorescence in order to investigate the regulation of S118 phosphorylation of Spo12 and its essential role for FEAR network function.
total:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk1 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:6
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Santa Cruz Biotechnology monoclonal anti-p55CDC antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
total:10
Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. 2009 to the paper
Santa Cruz Biotechnology anti-Cdc25A antibody was used in western blot in order to study the role of TRAIL for activation of DNA damage response pathways with histone H2AX and Chk2 phosphorylations. more
total:1
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. 2005 to the paper
BD Biosciences mouse anti-Cdc25B antibody was used in western blot to study the function of forkhead box M1 to regulate the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase.
total:20
Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growth.. 2008 to the paper
Epitomics anti-ATM antibody was used for western blot in order to investigate the role of Chk2 in the regulation of HSV-1 ICP0-mediated G2/M arrest and virus growth more
total:8
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol. 2010 to the paper
Abcam anti-CDC27 antibody was used to perform western blot in order to study the modulation of intracellular F. tularensis phagosome biogenesis and proliferation. more
total:9
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdc6 antibody was used to perform immunoprecipitation in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:1
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 to the paper
Neomarker Cdc7 antibody was used in immunoprecipitation to isolate Cdc7 from HeLa cells and in western blot to examine Cdc7 levels in HeLa.
total:4
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
ProteinTech polyclonal anti-Borealin was used to perform immunocytochemistry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:3
Combined deficiency of factor V and factor VIII is due to mutations in either LMAN1 or MCFD2. 2006 to the paper
R. F. Pettersson (Karolinska Institute) rabbit anti-P58 antibody was used in immunoprecipitation to deomnstrate that complete loss of the complex may not be required for clinically significant reduction in FV and FVIII. more
total:53
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk2 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:44
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 to the paper
Millipore anti-CDK4 antibody was used to perform western blot in order to study the roles of the fragile X mental retardation protein during the regulations of the proliferation and differentiation of adult neural stem/progenitor cells. more
total:20
Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA. 2010 to the paper
Abcam anti-Cdk6 antibody was used to carry out western blot analysis in order to investigate the role for Herpesvirus saimiri Noncoding RNA HSURs in the regulation of host cell microRNAs. more
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK7 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:1
Cyclin K and cyclin D1b are oncogenic in myeloma cells. 2010 to the paper
Santa Cruz anti-p15 was used to perform western blot in order to show the role of cyclin K and cyclin D1b in multiple myeloma.
total:1
Cyclin K and cyclin D1b are oncogenic in myeloma cells. 2010 to the paper
Santa Cruz anti-p18 was used to perform western blot in order to show the role of cyclin K and cyclin D1b in multiple myeloma.
total:3
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Proteintech Group Cdt1 antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:1
Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres. 2007 to the paper
Bill Earnshaw (Institute of Molecular and Cell Biology, Edinburgh, Scotland) rabbit polyclonal anti-CENP-C antibody was used in chromatin immunoprecipitation to study co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres
total:7
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
MBL International mouse anti-CenpA antibody (1:1,000) was used in immunocytochemistry in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation. more
total:3
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Abcam monoclonal anti-CENP-E antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
total:4
Expression of centromere protein F (CENP-F) associated with higher FDG uptake on PET/CT, detected by cDNA microarray, predicts high-risk patients with primary breast cancer. 2008 to the paper
Abcam CENP-F antibody (ab90, 1/200 dilution) was used to perform immunohistochemistry in order to clarify that high CENP-F expression was the prognostic indicator of primary breast cancer. more
total:2
Prognostic relevance of Centromere protein H expression in esophageal carcinoma. 2008 to the paper
Bethyl Laboratories anti-CENP-H rabbit polyclonal antibody was used in western blot in order to clarify the expression of Centromere protein H (CENP-H) in esophageal carcinoma and its correlation with clinicopathological features more
total:1
Premitotic assembly of human CENPs -T and -W switches centromeric chromatin to a mitotic state. 2011 to the paper
Bethyl anti-CENP-T antibody was used to perform western blot and immunofluorescence in order to study the effect of CENP-T and -W in the cell cycle.
total:1
Daughter centriole elongation is controlled by proteolysis. 2010 to the paper
BD Biosciences mouse anti-human C-Nap1 antibody was used to perform immunocytochemistry in order to study the role of proteolysis in daughter centriole elongation.
total:59
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 to the paper
Santa Cruz anti-Chk1 monoclonal antibody was used to perform western blot in order to study the interactions of ATR and ATRIP in gene expression and production of virus during HSV-1 infection. more
total:48
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. 2011 to the paper
Santa Cruz anti-chk2 was used to perform western blot and immunocytochemistry in order to show that chromosomal structural aberrations could be caused by chromosome segregation errors. more
total:1
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. 2005 to the paper
Zymed rabbit anti-Cks1 (C-term) antibody was used in western blot to study the function of forkhead box M1 to regulate the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase.
total:1
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GFP monoclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease.
total:6
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Bethyl Laboratories rabbit anti-Claspin antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
total:1
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 to the paper
Santa Cruz anti-CKI delta was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction
total:9
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 to the paper
Santa-Cruz Biotechnology anti-CK2 alpha antibody was used to carry out western blot analysis in order to investigate the role for NF-kB transcription factor in the interleukin-1 induced expression of C/EBP delta and APP genes. more
total:4
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 to the paper
Santa-Cruz Biotechnology anti-CK2 alpha' antibody was used to carry out western blot analysis in order to investigate the role for NF-kB transcription factor in the interleukin-1 induced expression of C/EBP delta and APP genes. more
total:2
CK2beta is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation. 2009 to the paper
Santa Cruz anti-CK2B antibody was used to perform western blot and immunohistochemistry in order to show the role of CK2B in apoptosis resistance and cell proliferation in endometrial carcinoma. more
total:12
Mediator acts upstream of the transcriptional activator Gal4. 2012 to the paper
Abcam anti-Cul1 mouse monoclonal antibody was used to perform immunoprecipitation in order to study how the Mediator initiated Gal4 transcription. more
total:39
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Santa Cruz Biotechnology monoclonal anti-cyclin A antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
total:64
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Thermo Fisher Scientific anti-cyclin B1 monoclonal antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
total:123
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-Cyclin D1 antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:20
Cyclin K and cyclin D1b are oncogenic in myeloma cells. 2010 to the paper
Santa Cruz anti-cyclin D2 was used to perform western blot in order to show the role of cyclin K and cyclin D1b in multiple myeloma. more
total:22
Identification of genes associated with cisplatin resistance in human oral squamous cell carcinoma cell line. 2006 to the paper
Proteintech Group anti-CCND3 antibody was used to perform western blot in order to find out the genes involved with cisplatin resistance in human oral squamous cell carcinoma cell line. more
total:55
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-cyclin E antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:3
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
BD Biosciences mouse anti-p50-dynamitin antibody (1:1,000) was used in immunocytochemistry in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation. more
total:1
Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment. 2005 to the paper
Research Genetics/Invitrogen rabbit anti-human DHFR polyclonal antibody was used in western blot to study the essential of identification of amino acids for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate treatment.
total:4
Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex. 2006 to the paper
GeneTex DNA ligase I antibody (10H5) was used in western blot to detect DNA ligase I in human TK6 cells more
total:7
Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development. 2010 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-rat Dync1h1 antibody was used to perform western blot and immunohistochemistry in order to study the multiple functions of Dynein1 in zebrafish retinal photoreceptor development. more
total:3
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix. 2009 to the paper
Abcam monoclonal anti-dynein antibody (74.1ab23905) was used in blocking or activating expriments to study the roles for nudel and dynein in assembly of the lamin B spindle matrix. more
total:37
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Santa Cruz E2F1 antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:11
Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor. 2007 to the paper
Santa Cruz anti-E2F4 was used to perform ChIP assays in order to show that the evolutionarily conserved gene targets of E2F4 play important roles for cell cycle. more
total:7
Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement. 2010 to the paper
Novacastra Laboratories mouse monoclonal anti-Emerin antibody was used to carry out immunofluorescence assays in order to investigate the mechanims for nuclear movement to reorient the centrosome in migrating fibroblasts. more
total:252
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Millipore anti-ERK1/2 polyclonal antibody (1:10,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediated anti-apoptotic effects. more
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:2
Flap endonuclease 1 is overexpressed in prostate cancer and is associated with a high Gleason score. 2006 to the paper
Novocastra monoclonal anti-FEN-1 antibody was used in immunohistochemistry to investigate the expression and potential clinical usefulness of structure-specific flap endonuclease 1 (FEN-1) in human primary prostate cancer. more
total:1
Daughter centriole elongation is controlled by proteolysis. 2010 to the paper
Proteintech Group rabbit anti-human FGFR1OP antibody was used to perform immunocytochemistry in order to study the role of proteolysis in daughter centriole elongation.
total:5
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. 2010 to the paper
Millipore mouse monoclonal anti-MPM-2 antibody was used to carry out immunofluorescence assays in order to investigate the mechanism for Haspin-mediated histone H3 thr-3 phosphorylation regulating chromosomal passenger complex accumulation at centromeres. more
total:2
Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis. 2008 to the paper
Calbiochem Cdh1 antibody was used in western blot in order to study the role of Cdh1/APC in tumorigenesis more
total:38
Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. 2012 to the paper
Sigma-Aldrich rabbit anti-gamma tubulin was used to perform immunocytochemistry in order to show that ciliogenesis was regulated by an evolutionarily assembled cis-regulatory module more
total:1
Stargardt-like macular dystrophy protein ELOVL4 exerts a dominant negative effect by recruiting wild-type protein into aggresomes. 2005 to the paper
Sigma-Aldrich anti-tubulin antibody was used in western blot and immunocytochemistry to study the dominant negative effect by recruiting wild-type protein into aggresomes of the Stargardt-like macular dystrophy protein ELOVL4.
total:5
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 to the paper
Santa Cruz anti-Geminin was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction more
total:61
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 to the paper
Abcam rabbit anti-Gm130 antibody was used to perform immunoelectron microscopy in order to investigate the mechanism of Golgi-mediated protein traffic. more
total:2
TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells. 2013 to the paper
Santa Cruz Biotechnology anti-GRASP65 antibody was used to perform immunocytochemistry in order to investigate the regulatory effect of TRPM5 activation on MUC5AC secretion from human colon goblet cells. more
total:1
GRASP55 and GRASP65 play complementary and essential roles in Golgi cisternal stacking. 2010 to the paper
Proteintech Group Inc rabbit polyclonal anti-GRASP55 antibody(Catalog No.: 10598-1-AP, 37ug/150 ul)was used to perform western blot and immunocytochemistry assays in order to demonstrate the molecular mechanisms of GRASP55 and GRASP65 in Golgi cisternal stacking.
total:1
Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. 2007 to the paper
Dr. Peter Cheung (Ontario Cancer Institute) rabbit H2A.Z-specific antibodies (the H2A.Z-L1 antibody was raised against the peptide sequence KSSRTTSHGR, and the H2A.Z-C antibody was raised against the peptide sequence IPHIHKSLIGKKGQQKTV) was used in western blot and immunocytochemistry to study H2A.Z monoubiquitylation as the marker for its association with euchromatin or facultative heterochromatin
total:62
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Millipore Gamma-H2AX antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:32
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-H3K4 antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
total:5
Hsp90alpha recruited by Sp1 is important for transcription of 12(S)-lipoxygenase in A431 cells. 2005 to the paper
Upstate Biotechnology acetyl-H3 antibody was used in ChIP assay to study 12 (S) Lipoxygenase transcription in A431 cells more
total:11
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Active Motif anti-H4K12Ac antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:54
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-HDAC1 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:3
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Santa Cruz Biotechnology anti-HDAC8 antibody was used to perform western blot in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:1
Testis/sperm-specific histone 2B in the sperm of donors and subfertile patients: variability and relation to chromatin packaging. 2007 to the paper
Chemicon International TSH2B antibody was used in western blot to assesse the association of TSH2B with chromatin compaction status.
total:1
p53 chromatin epigenetic domain organization and p53 transcription. 2009 to the paper
Abcam anti-histone H2Bantibody was used to perform immunoprecipitation in order to demonstrate that physical barrier due to the folding of chromatin in domain II can give rise to the depletion of RNA polymerase II.
total:5
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Abcam anti-Histone 3, anti-H3 K9Me, and anti-H3 S10ph antibodies were used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:6
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Abcam anti-H2A antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:10
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-H2B antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:17
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Millipore rabbit anti-pHH3 was used at 1:500 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:68
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-HSP90 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:1
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Santa Cruz anti-Hus1 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses.
total:6
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Santa Cruz Biotechnology anti-inner centromeric protein antibody was used in immunocytochemistry in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis. more
total:6
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Abcam anti-MKLP2 antibody was used in immunocytochemistry in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis. more
total:1
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. 2010 to the paper
Abnova mouse monoclonal anti-MCAK antibody was used to carry out immunoblotting assays in order to investigate the mechanism for Haspin-mediated histone H3 thr-3 phosphorylation regulating chromosomal passenger complex accumulation at centromeres.
total:57
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Santa Cruz lamin A/C goat polyclonal (1:1000)was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more
total:31
CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin. 2010 to the paper
Santa Cruz anti-lamin-B antibody was used for western blot in order to show that CYLD negatively regulates cell-cycle progression by inactivating HDAC6. more
total:2
Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1. 2008 to the paper
Santa Cruz Biotechnology anti-mad1 antibody was used for western blot in order to investigate the roles of PI3K/Akt and MAPK pathways in the regulation of Myc-mediated transcription more
total:11
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. 2010 to the paper
Immuquest anti-MAD2 antibody was used in western blot in order to investigate the different expression levels of spindle proteins in the testicular germ cell tumors. more
total:3
Mammalian end binding proteins control persistent microtubule growth. 2009 to the paper
BD Biosciences anti-EB1 mouse monoclonal antibody was used in immunohistochemistry and western blot in order to show that persistent microtubule growth can be regulated by end binding proteins in mammal. more
total:8
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 to the paper
BD Biosciences antibody to total Mcm2 was used in western blot to examine the levels of total Mcm2 in HeLa cells. more
total:5
Orc1 controls centriole and centrosome copy number in human cells. 2009 to the paper
Santa Cruz Biotechnology rabbit pAb anti-MCM3 antibody was used for western blot in order to demonstrate that the copy numbers of centriole and centrosome were regulated by Orc1 in human cells. more
total:1
The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. 2010 to the paper
Acbam anti-MCM4 antibody was used for western blot in order to investigate the role of the ETG1 in the regulation of endogenous DNA stress.
total:2
The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation. 2005 to the paper
Bethyl Laboratories MCM5 antibody was used in ChIP assay to study the role of DNA replication factor MCM5 in Stat1-mediated transcriptional activation more
total:2
The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. 2010 to the paper
Acbam anti-MCM6 antibody was used for western blot in order to investigate the role of ETG1 in the regulation of endogenous DNA stress. more
total:6
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Mcm7 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:2
Differential regulation of centrosome integrity by DNA damage response proteins. 2008 to the paper
Proteintech anti-BRIT1 antibody was used to perform immunohistochemistry in order to study the functions of MDC1 and BRIT1 in the centrosome maturation and spindle assembly. more
total:38
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. 2010 to the paper
Calbiochem anti-Hdm2 antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis. more
total:24
Small ubiquitin-related modifier (SUMO)-1, SUMO-2/3 and SUMOylation are involved with centromeric heterochromatin of chromosomes 9 and 1 and proteins of the synaptonemal complex during meiosis in men. 2008 to the paper
Calbiochem anti-MLH1 antibody (1:75) was used to perform western blot and immunoprecipitation in order to study the function of small ubiquitin-related modifier (SUMO) 1, SUMO-2/3 and SUMOylation. more
total:2
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". 2006 to the paper
Santa Cruz monoclonal anti-Mat1 antibody (F-6) was used in human T98G cells and in western blot to study the role for cyclins and CDK "inhibitors" in Thr172 phosphorylation of CDK4. more
total:19
The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection.. 2009 to the paper
Calbiochem rabbit polyclonal Mre11 antibody was used to perform western blot in order to investigate the relations between E1B-55K/E4orf6 and eIF2. more
total:1
Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair. 2009 to the paper
BD Biosciences rabbit anti-Msh4 antibody was used for western blot in order to investigate the role of Syce1 in the regulation of Synapsis and DNA Repair.
total:28
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Novus NBS1 antibody was used to perform immunofluorescence assay in order to study the requirement of RSFI in DSB repair. more
total:4
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Abcam anti-Hec1 antibody was used in immunocytochemistry in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis. more
total:1
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
Proteintech Group rabbit anti-Nde1 antibody (1:1,000) was used in immunocytochemistry in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation.
total:2
Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis. 2008 to the paper
Abgent anti-human NEK6 was used to perform western blot in dilution 1:500 in order to show that differentially overexpressed genes in gastric cancer are revealed by combining large-scale gene expression profiling and network analysis. more
total:11
Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. 2010 to the paper
Zymed anti-NPM antibody was used for western blot in order to investigate the role for activated Bax in the regulation of p53-dependent, transcription-independent neural precursor cell apoptosis. more
total:8
Fractionation of the Coxiella burnetii parasitophorous vacuole. 2008 to the paper
BD Biosciences mouse anti-human nuclear pore protein nucleoporin p62 antibody was used to perform western blot in order to develope a method to separate intact parasitophorous vacuole from host cell material. more
total:1
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 to the paper
Santa Cruz anti-NUDC antibody was used to perform western blot in order to study the role of non-directed activity-based protein profiling plays in the identification of enzymes that are either predominantly or exclusively labeled in living cells.
total:1
Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.. 2009 to the paper
Sigma-Aldrich anit-VSVG antibody was used to perform immunocytochemistry to study the role of cPLA2a in the formation of intercisternal tubular continuities and transport through the Golgi complex.
total:4
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor. 2009 to the paper
Santa Cruz Biotechnology goat anti-NuMA polyclonal antibody was used to perform western blot and immunoprecipitation assays in order to demonstrate that the interaction of NuMA with LANA plays a great role in KSHV genome maintenance and segregation. more
total:1
The nucleoporin Nup153 has separable roles in both early mitotic progression and the resolution of mitosis. 2009 to the paper
Covance anti-nucleoporin antibody was used to perform western blot in order to study the roles of Nup153 plays in mitosis.
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Abcam monoclonal anti-NUP was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:1
Caspases target only two architectural components within the core structure of the nuclear pore complex. 2006 to the paper
BD Biosciences monoclonal Nup88 antibody was used in western blot to identify caspase targets in the core structure of nuclear pore complex in Hela cells
total:1
A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution. 2010 to the paper
Sigma-Aldrich rabbit polyclonal anti-Odf2 antibody was used to carry out immunofluorescence assays in order to investigate the role for SEPT2 as diffusion barrier in the reguation of receptor-signaling pathways in the primary cilium.
total:1
Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. 2010 to the paper
GenTex anti-OFD1 antibody was used to perform immunofluorescence in order to investigate SDCCAG8 loss of function during heterogeneous single-gene disorders.
total:3
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. 2011 to the paper
immunGlobe anti-OPTN was used to perform western blot and immunocytochemistry in order to show that Salmonella enterica growth was restricted by phosphorylation of autophagy receptor optineurin. more
total:1
p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation. 2005 to the paper
Abcam ORC1 antibody was used in western blot to investigate the regulation of Cdc6 protein stability by p53.
total:7
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Orc2 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:1
Orc1 controls centriole and centrosome copy number in human cells. 2009 to the paper
Abcam goat pAb anti-Orc4 antibody was used for western blot in order to demonstrate that the copy numbers of centriole and centrosome were regulated by Orc1 in human cells.
total:8
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p107 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:5
SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development. 2006 to the paper
BD Biosciences Pharmingen mouse monoclonal p115 (clone 15, IgG1) antibody was used in immunocytochemistry to study the enrichment of SPG3A protein atlastin-1 in growth cones and its promotion of axon elongation during neuronal development. more
total:7
Control of cellular senescence by CPEB. 2006 to the paper
Santa Cruz Biotechnology p130 antibody was used in western blot to study the role of CPEB in cellular senescence. more
total:9
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Santa Cruz p150Glued antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:49
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-p19 antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:178
Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 to the paper
Abcam mouse anti-p21 antibody was used to perform western blot in order to study the mechanism through which doxorubicin suppressed tumor growth. more
total:118
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 to the paper
BD Pharmingen anti-p27CDKN1B antibody was used to perform western blot in order to show that p53-dependent cell proliferation and survival could be regulated by atg7. more
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal regulator PA200 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
total:6
NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90. 2010 to the paper
Sigma anti-LIS1 antibody was uesd to perform western blot in order to study the regulation of the LIS1/dynein pathway by NudC-like protein 2 via stabilizing LIS1 with Hsp90. more
total:84
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Santa Cruz anti-PCNA was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:8
Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse. 2011 to the paper
Abcam anti-pericentrin antibody was used to perform immunocytochemistry in order to study the secretion of natural killer cell lytic granule at the immune synapse. more
total:1
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. 2010 to the paper
Abcam anti-H4K20me1 antibody was used in western blot in order to investigate the mechanism of how the embryonic stem cells chromatin structure change was regulated by condensin complexes during mitotic progression.
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
total:27
Protein kinase C in porcine retinal arteries and neuroretina following retinal ischemia-reperfusion. 2009 to the paper
Santa Cruz Biotechnology mouse monoclonal anti-beta-actin antibody (1:5000) was used for western blot in order to investigate the role of PKC in the regulation of porcine retinal ischemia-reperfusion. more
total:29
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Plk1 antibody was used to perform immunoprecipitation in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:1
p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. 2012 to the paper
Sigma anti-p180 (polyclonal) antibody was used to perform immunoblotting in order to study the effect of p180 on the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum.
total:2
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Proteintech anti-POLD1 was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2Ac antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:2
Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma. 2007 to the paper
Santa Cruz Biotechnology goat polyclonal PP1 gamma C antibody was used in western blot to study the regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma more
total:10
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 to the paper
Upstate Cell Signalling Solutions anit-MYPT1 antibody was used to perform western blot to study the different roles of ROCK1 and ROCK2 in regulating keratinocyte adhesion and terminal differentiation. more
total:2
Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma. 2008 to the paper
Upstate anti-MYPT and anti-phospho-MYPT (Thr853) were used to perform western blot in order to show that Rho/ROCK/MLC pathway could be inhibited by DCL1 in hepatocellular carcinoma. more
total:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate polyclonal anti-PP2A-A antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 to the paper
Sigma-Aldrich polyclonal antibody to the PP2APR65 subunit was used to perform western blot in order to investigate the functions of salt-inducible kinase-1. more
total:2
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2A-B antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:3
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIIbeta was used in immunohistochemistry to detect the PKA subunit RIIbeta in human adrenal samples more
total:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 to the paper
Abcam C2 proteasome antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway more
total:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Santa Cruz Biotechnology anti-Psc3 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International mouse monoclonal anti-human 20S proteasome subunit alpha4 was used for immunohistochemistry to investigate the effect of immunoproteasome on the Multiple Sclerosis pathogenesis. more
total:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Enzo Life Sciences anti-alpha7 antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:2
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta1 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD). more
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP7 antibody was used for immunohistochemistry to study the effect of immunoproteasome on the Multiple Sclerosis. more
total:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP2 antibody was used to perform immunohistochemistry to study the role of immunoproteasome in the Multiple Sclerosis pathogenesis. more
total:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 to the paper
Cell Signaling Technology anti-phospho-Ser235/236-S6 antibody was used to perform immunocytochemistry in order to study the capacity of rapamycin to provide neuroprotection in Parkinson disease models. more
total:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 to the paper
New England BioLabs antiphospho-p44/42 MAPK antibody and p44/42 MAPK antibody (PhosphoPlus p44/42 MAPK antibody kit) was used in western blot to study the physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing RhoGEFs.
total:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S2 subunit antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication.
total:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S5a antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication. more
total:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p27 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International rabbit polyclonal anti-PA28alpha antibody was used for immunohistochemistry to determine the role of immunoproteasome in the Multiple Sclerosis. more
total:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 to the paper
BIOMOL anti-proteasome activator 28 subunit beta (PA28beta) antibodoy was used to perform western blot in order to confirm the effect on the expression of proteasome-interacting proteins caused by chronic ethanol feeding.
total:1
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Santa Cruz Biotechnology rabbit polyclonal Rab1b antibody was used in western blot and immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association
total:2
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-RAB2A antibody was used to perform IP in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
total:4
Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice. 2007 to the paper
BD Biosciences anti-Rab8 antibody was used to carry out immunofluorescence assays in order to investigate the role for Dlg5 in the maintenance of epithelial tube in mammalian brain and kidneys. more
total:2
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Novus Biologicals anti-Rad1 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:7
Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway. 2010 to the paper
Bethyl Laboratories anti-Rad17 antibody was used for western blot in order to investigate the roles of MutSalpha and MutLalpha in the regulation of ATR-Chk1 pathway. more
total:2
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Novus anti-human Rad21 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:13
Differential requirements of the C terminus of Nbs1 in suppressing adenovirus DNA replication and promoting concatemer formation. 2008 to the paper
GeneTex anti-Rad50 antibody was used to perform western blot in order to identify that regions of Nbs1 are differentially required for concatemer formation and inhibition of Ad DNA replication. more
total:20
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Calbiochem anti-Rad51 was used to perform immunocytochemistry in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:7
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Bethyl anti-Rad9 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:1
The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response. 2008 to the paper
R&D Systems anti-RAE-1 antibody was used in flow cytometry in order to study the role of immune responses in the tumorigenicity of embryonic stem cells
total:4
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
Santa Cruz polyclonal anti-RanBP2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
total:77
LIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma: clinical and prognostic implications. 2010 to the paper
Santa Cruzrabbit polyclonal anti-pRB antibody was used to perform immunohistochemistry in order to study the role of two interacting proteins LIMD1 and pRB in development of head and neck squamous cell carcinoma (HNSCC). more
total:6
CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene. 2006 to the paper
Abcam RbAp46 antibody was used in immunoprecipitation to study the molecular mechanism (s) by which CTIP2 contributes to T cell development and axonal. more
total:8
The polycomb repressive complex 2 is a potential target of SUMO modifications. 2008 to the paper
Upstate rabbit anti-RbAp48 13D10 was used to perform western blot in order to show that the polycomb repressive complex 2 could be sumoylated post-translationally. more
total:3
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Abcam anti-SAE2 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
total:1
Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe. 2006 to the paper
Santa Cruz Biotechnology anti-REC8 antibody was used in western blot and immunocytochemistry to study the upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe.
total:1
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
Abnova mouse anti-Rod antibody (1:100) was used in immunocytochemistry in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation.
total:12
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 to the paper
GeneTex anti-RPA32 monoclonal antibody was used to perform immunofluorescence in order to study the interactions of ATR and ATRIP in gene expression and production of virus during HSV-1 infection. more
total:3
Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation. 2009 to the paper
Millipore anti-Mps1 antibody was used to perform immunohistochemistry in order to study the regulation of Mps1 phosphorylation in kinetochore targeting and spindle checkpoint signaling. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:2
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization. 2008 to the paper
Proteintech rabbit anti-RUVBL1 antibody was used for western blot in order to investigate the role of ILK in the regulation of mitotic spindle organization. more
total:1
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. 2008 to the paper
Abcam anti-H4K20me1, me2, me3 antibodies (Ab9051, Ab9052, and Ab9053) were used in ChIP assay to study FoxA1 differential transcriptional activities in breast and prostate cancer cells and their functional relation with the epigenome of these cells.
total:1
Mutational inactivation of STAG2 causes aneuploidy in human cancer. 2011 to the paper
Novus Biologicals anti-SGOL1 was used to perform western blot in order to show that aneuploidy in tumor cells is associated with STAG2 inactivation.
total:8
APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. 2009 to the paper
Zymed mouse monoclonal anti-Skp1 antibody was used in western blot to investigate the regulation of Cdc20 stability during SAC activation in mammalian cells and explore the contribution of spindle checkpoint proteins to Cdc20 stability. more
total:17
Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy. 2009 to the paper
Zymed anti-Skp2 was used in 1:1000 dilution to perform western blot in order to show that CSN plays an important role for cell autophagy in K562 cells. more
total:4
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Bethyl Laboratories SNF2H antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:14
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Bethyl anti-SMC1 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:1
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. 2010 to the paper
Abcam anti-Smc2 antibody was used in western blot in order to investigate the mechanism of how the embryonic stem cells chromatin structure change was regulated by condensin complexes during mitotic progression.
total:2
DNMT3B mutations and DNA methylation defect define two types of ICF syndrome. 2005 to the paper
Upstate Biotechnology rabbit anti-hCAP-C antibody was used in western blot and immunocytochemistry to study the isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery. more
total:2
Mutational inactivation of STAG2 causes aneuploidy in human cancer. 2011 to the paper
Santa Cruz anti-STAG1 was used to perform western blot in order to show that aneuploidy in tumor cells is associated with STAG2 inactivation. more
total:1
Mutational inactivation of STAG2 causes aneuploidy in human cancer. 2011 to the paper
Santa Cruz anti-STAG2 was used to perform western blot and immunohistochemistry in order to show that aneuploidy in tumor cells is associated with STAG2 inactivation.
total:1
Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair. 2009 to the paper
Upstate Biotechnology rabbit anti-STAG3 antibody was used for western blot in order to investigate the role of Syce1 in the regulation of Synapsis and DNA Repair.
total:1
Induction of a massive endoplasmic reticulum and perinuclear space expansion by expression of lamin B receptor mutants and the related sterol reductases TM7SF2 and DHCR7. 2010 to the paper
Sigma/Atlas Antibodies rabbit anti-Sun1 antibody was used in immunohistochemistry in order to investigate the effects of the expression of human LBR disease mutants on cellular structure.
total:33
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Novus Biologicals rabbit polyclonal anti-Survivin antibody was used to carry out western blot analysis in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:1
Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair. 2009 to the paper
Abcam rabbit anti-SYCE1 antibody was used for western blot in order to investigate the role of Syce1 in the regulation of Synapsis and DNA Repair.
total:1
Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair. 2009 to the paper
Abcam rabbit anti-SYCE2 antibody was used for western blot in order to investigate the role of Syce1 in the regulation of Synapsis and DNA Repair.
total:2
Small ubiquitin-related modifier (SUMO)-1, SUMO-2/3 and SUMOylation are involved with centromeric heterochromatin of chromosomes 9 and 1 and proteins of the synaptonemal complex during meiosis in men. 2008 to the paper
Santa Cruz Biotechnology anti-SCP1 antibody (1:100) was used to perform western blot and immunoprecipitation in order to study the function of small ubiquitin-related modifier (SUMO) 1, SUMO-2/3 and SUMOylation. more
total:1
Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair. 2009 to the paper
Abcam mouse anti-SYCP3 antibody was used for western blot in order to investigate the role of Syce1 in the regulation of Synapsis and DNA Repair.
total:2
Lamin A/C-mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy. 2009 to the paper
Santa Cruz Biotechnology Nesprin-1 antibody was used in immunohistochemistry in order to demonstrate that lamin A/C-mediated NMJ defects contribute to the AD-EDMD disease phenotype more
total:2
TAO kinases mediate activation of p38 in response to DNA damage. 2007 to the paper
BD Biosciences mouse anti-TAO1 antibody was used in western blot to study the role of TAO kinases in DNA damage response. more
total:10
The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model. 2010 to the paper
Calbiochem anti-TERT antibody (1:350) was used to perform immunohistochemistry in order to study the function of pAkt on posterior capsule more
total:1
Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair. 2009 to the paper
Abcam rabbit anti-TEX12 antibody was used for western blot in order to investigate the role of Syce1 in the regulation of Synapsis and DNA Repair.
total:1
Identification and characterization of novel isoforms of human DP-1: DP-1{alpha} regulates the transcriptional activity of E2F1 as well as cell cycle progression in a dominant-negative manner. 2005 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-DP-1 antibody was used in western blot to identify and Characterize the novel isoforms of human DP-1.
total:3
Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope. 2005 to the paper
BD Biosciences mouse anti-LAP2beta antibody was used in immunocytochemistry to study the Lamin A/C dependent localization of Nesprin-2 as a giant scaffolder at the nuclear envelope more
total:7
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells. 2008 to the paper
Oncogene Research Products Topoisomerase II antibody was used to perform immunoblotting in order to demonstrate the mechanism between Rac1 and the canonical Wnt signalling pathway in colorectal cancer cells. more
total:5
Functional dissection of human and mouse POT1 proteins. 2009 to the paper
Sigma rabbit anti-mouse TRF1 (644) antibody was used in immunofluorescence in order to investigate the function of single-stranded telomeric DNA associated protein-POT1 in human and mice. more
total:16
Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins. 2009 to the paper
Millipore anti-TRF2 antibody was used to perform immunohistochemistry in order to study the function of HP1 proteins in the alternative lengthening of telomeres-associated PML bodies by p53/p21. more
total:117
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Sigma mouse anti-alpha-tubulin was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:29
Overcoming mutation-based resistance to antiandrogens with rational drug design. 2013 to the paper
Santa Cruz Biotechnology anti-beta-tubulin (D-10) antibody was used to perform western blot in order to study the rational drug design for castration-resistant prostate cancer without mutation-based resistance to antiandrogens. more
total:2
Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. 2005 to the paper
Sigma monoclonal beta IV-tubulin antibody was used in immunohistochemistry to characterize wild-type and mutant cystic fibrosis transmembrane regulator in human respiratory epithelia more
total:1
Targeting tumor angiogenesis with histone deacetylase inhibitors: the hydroxamic acid derivative LBH589. 2006 to the paper
Sigma tubulin antibody was used in western blot to characterize the antiangiogenic and antitumor activity of the hydroxamic derivative LBH589.
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:3
Novel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7. 2009 to the paper
Boston Biochem anti-UbcH10 antibody was used to perform immunohistochemistry in order to study the regulation of ubiquitin-conjugating enzyme H7 in S phase of the cell cycle. more
total:1
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes. 2007 to the paper
Boston Biochem anti-UbcH5 antibody was used to perform immunoprecipitation in order to study the roles of the DET1 during the regulation of the Cul4A activity.
total:10
The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 to the paper
Santa Cruz anti-UBC9 antibody was used in western blot in order to find the counterpart of forkhead transcription factor- FOXL2 and elucidate the role of its sumoylation more
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-WEE1 antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
total:7
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. 2009 to the paper
Santa Cruz Biotechnology CRM-1 antibody was used for Western blotting in order to investigate the effect of LKB1 on nucleocytoplasmic transport. more
total:2
A mammalian NudC-like protein essential for dynein stability and cell viability. 2006 to the paper
Antibodies anti-CREST antibody was used in western blot in order to demonstrate that NudC-like protein (NudCL) plays an essential role in mitosis and contributes to stabilization of the dynein complex. more