CaM pathway
gene
reagent
sample publication
sample review
ADCY1
adenylate cyclase 1
total:2
Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. 2005 to the paper
FabGennix isoform-specific anti-adenylate cyclase antibody was used in western blot to study the effedt of interferon-gamma on adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia. more
ADCY2
adenylate cyclase 2
total:2
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. 2007 to the paper
Santa Cruz Biotechnology AC2 antibody was used in western blot to demonstrate stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. more
ADCY3
adenylate cyclase 3
total:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Santa Cruz anti-adenylyl cyclase III antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
ADCY5
adenylate cyclase 5
total:3
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 to the paper
Santa Cruz Biotechnology anti-adenylate cyclase antibody was used in western blot to study the role of PDE3B and its interaction with PKB for regulation of specific cAMP pools and signalling pathways by insulin. more
CAMK4
calcium/calmodulin dependent protein kinase IV
total:3
Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation. 2005 to the paper
Transduction Laboratories monoclonal anti-CaMKIV antibody was used in western blot and immunocytochemistry to study the presence of CaMKIV in mammalian sperm and its role in the regulation of human sperm motility. more
CREB
cAMP responsive element binding protein 1
total:58
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
GRK2
G protein-coupled receptor kinase 2
total:9
Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2. 2008 to the paper
Santa Cruz Biotechnolog GRK2 polyclonal antibody was used to immunodetect myocardial levels in order to study the uncoupling of myocardial beta-Adrenergic receptor signaling during coronary artery bypass grafting: The Role of GRK2 more
PDE1B
phosphodiesterase 1B
total:2
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. 2006 to the paper
Chemicon PDE1B1 antibody was used in western blot to study Cellular and subcellular localization of PDE10A. more
PKC alpha
protein kinase C alpha
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
PKC delta
protein kinase C delta
total:35
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. 2009 to the paper
Santa Cruz Biotechnology anti-PKCdelta antibody was used in western blot to study the mechanism underlying PKCalpha suppressing tumor in the intestine. more
PRKACA
protein kinase cAMP-activated catalytic subunit alpha
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
PRKACG
protein kinase cAMP-activated catalytic subunit gamma
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
total:9
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIalpha was used in immunohistochemistry to detect the PKA subunit RIalpha in human adrenal samples more
PRKAR2A
protein kinase cAMP-dependent type II regulatory subunit alpha
total:9
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Santa Cruz Biotechnology anti-PKA RII antibody was used in immunoprecipitation in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
PRKAR2B
protein kinase cAMP-dependent type II regulatory subunit beta
total:3
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIIbeta was used in immunohistochemistry to detect the PKA subunit RIIbeta in human adrenal samples more
PRKCG
protein kinase C gamma
total:12
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. 2007 to the paper
Cell Signaling Technology phospho-Pan-PKC antibody (1:1,000) was used in western blot to study melanoma cell motility by the Wnt5A/protein kinase C pathway through the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition more