CD molecules
gene
reagent
sample publication
sample review
ABCB1
ATP binding cassette subfamily B member 1
total:15
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Santa Cruz Biotechnology MDR1 antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
ABCG2
ATP binding cassette subfamily G member 2 (Junior blood group)
total:7
Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma. 2010 to the paper
Abcam anti-ABCG2 antibody was used to perform western blot in order to study the role of LMP2A in the nasopharyngeal carcinoma progression. more
ACE
angiotensin I converting enzyme
total:8
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Santa Cruz anti-ACE was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
ADAM8
ADAM metallopeptidase domain 8
total:3
The detection of ADAM8 protein on cells of the human immune system and the demonstration of its expression on peripheral blood B cells, dendritic cells and monocyte subsets. 2007 to the paper
R&D Systems mouse anti-human ADAM8 antibody (1:2500 dilution) was used in western blot to study the role of ADAM8 in allergic responses. more
ADAM10
ADAM metallopeptidase domain 10
total:10
S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10. 2009 to the paper
Chemicon ADAM-10 antibody was used for western blot in order to indentify new biomarker of Alzheimer's disease. more
ADAM17
ADAM metallopeptidase domain 17
total:13
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. 2008 to the paper
Santa Cruz Biotechnology anti-TACE antibody was used to perform Western Blot in order to show that TACE has a inhibitory role in EGFR axis in colorectal cancer. more
ALCAM
activated leukocyte cell adhesion molecule
total:5
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
BD Biosciences anti-CD166 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
ALK
ALK receptor tyrosine kinase
total:7
The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL. 2009 to the paper
Zymed Laboratories mouse anti-ALK (1:4000, 4C5B8) antibody was used to study the role of ALK in the pathogenesis and the treatment of anaplastic large cell lymphoma. more
CD13
alanyl aminopeptidase, membrane
total:14
Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. 2009 to the paper
Santa Cruz anti-aminopeptidase N antibody was used in immunohistochemistry in order to investigate the role of neprilysin in the regulation of pulmonary vascular remodeling in response to chronic hypoxia. more
ATP1B3
ATPase Na+/K+ transporting subunit beta 3
total:5
Control of chemokine gradients by the retinal pigment epithelium. 2008 to the paper
Abcam Na, K-ATPase antibody was used in immunocytochemistry in order to examine the physiological responses of human fetal retinal pigment epithelia (hfRPE) after polarized activation of proinflammatory cytokine receptors in vitro more
CD57
beta-1,3-glucuronyltransferase 1
total:9
Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival. 2008 to the paper
Becton Dickinson anti-CD57 antibody was used in immunohistochemistry to investigate the relationship between IDO expression and tumor-infiltrating lymphocytes in endometrial cancer. more
CXCR5
C-X-C motif chemokine receptor 5
total:4
Striking alteration of some populations of T/B cells in systemic lupus erythematosus: relationship to expression of CD62L or some chemokine receptors. 2008 to the paper
R&D phycoerythrin(PE)-conjugated anti-CXCR5 (51505) antibody was used to perform flow cytometry and immunocytochemistry in order to study the relationship between striking alteration of some populations of T/B cells and expression of CD62L or some chemokine receptors in patients with systemic lupus erythematosus. more
BMPR1A
bone morphogenetic protein receptor type 1A
total:5
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. 2006 to the paper
Santa Cruz Biotechnology anti-BMPR1a antibody was used to perform immunocytochemistry in order to study the regulatory effects of highly expressed bone morphogenetic protein 4(BMP4) and Gremlin toward myogenic progenitor proliferation in human fetal skeletal muscle. more
BMPR1B
bone morphogenetic protein receptor type 1B
total:3
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1. 2005 to the paper
R & D Systems anti-BMP-RIB was used to perform western blot in order to show that in mature human B cells BMP-6 could regulate Smad phosphorylation, Id1 expression, and cell growth. more
CD147
basigin (Ok blood group)
total:15
Upregulation of EMMPRIN after permanent focal cerebral ischemia. 2008 to the paper
Serotec rat anti-EMMPRIN monoclonal antibody (1:200) was used in immunohistochemistry in order to examine potential association between EMMPRIN and MMP-9 expre more
BST2
bone marrow stromal cell antigen 2
total:2
BST-2 diminishes HIV-1 infectivity. 2010 to the paper
NIH AIDS Research and Reference Reagent Program antiserum anti-human BST-2 antibody was used to perform western blot in order to study the infectivity of HIV-1 reduced by BST-2. more
CCR1
C-C motif chemokine receptor 1
total:3
A key role for CC chemokine receptor 1 in T-cell-mediated respiratory inflammation. 2008 to the paper
Capralogics rabbit anti-human CCR1 antibody was used in flow cytometry at a dilution of 1:200 to stduy the role for CC chemokine receptor 1 in T-cell-mediated respiratory inflammation. more
CCR5
C-C motif chemokine receptor 5 (gene/pseudogene)
total:28
Effects of ferumoxides-protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells. 2008 to the paper
Biolegend FITC conjugated mouse anti-human CD195 IgG2a was used in flow cytometry in order to demonstrate that endocytosed FePro nanoparticles did not significantly affect immunological properties of THP-1 cells more
CCR6
C-C motif chemokine receptor 6
total:5
CC chemokine receptor 6 expression by B lymphocytes is essential for the development of isolated lymphoid follicles. 2007 to the paper
R&D Systems rat anti-mouse CCR6 antibody was used in flow cytometry to study the role for CCR6 in the development of isolated lymphoid follicles (ILFs). more
CCR7
C-C motif chemokine receptor 7
total:9
Role of Twist in head and neck carcinoma with lymph node metastasis. 2008 to the paper
R&D Systems anti-CCR7 monoclonal antibody was used to perform immunohistochemistry in order to study the role of twist in metastasis of head and neck carcinoma. more
CCR8
C-C motif chemokine receptor 8
total:3
Autocrine and paracrine promotion of cell survival and virus replication by human herpesvirus 8 chemokines. 2008 to the paper
Epitomics anti-CCR8 antibody was used in western blot to study the effect of human herpesvirus 8 chemokines on endothelial survival and virus replication. more
CCR9
C-C motif chemokine receptor 9
total:1
CCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion. 2010 to the paper
R&D Systems PE-conjugated mouse anti-human CCR9 (clone 112509) antibody was used to perform flow cytometry in order to study the interactions between CCL25 and CCR9 in ovarian carcinoma cell migration and invasion.
CD1a
CD1a molecule
total:15
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
BD Pharmingen anti-CD1a-FITC was used to perform flow cytometry in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more
CD1B
CD1b molecule
total:1
Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function. 2006 to the paper
Santa Cruz Biotechnology CD1 antibody was used in immunoprecipitation to study the association of ILT2 and murine MHC class I molecules in vivo.
CD1C
CD1c molecule
total:2
Mycobacterial disease and impaired IFN-? immunity in humans with inherited ISG15 deficiency. 2012 to the paper
BD Biosciences anti-CD1c was used to perform flow cytometry in order to show that ISG15 deletion in humans impairs IFN-gamma immunity and results in mycobacterial disease susceptibility. more
CD1D
CD1d molecule
total:5
A novel IL-17-dependent mechanism of cross protection: respiratory infection with mycoplasma protects against a secondary listeria infection. 2009 to the paper
BD PharMingen anti-NK1.1 antibody was used in flow cytometry in order to investigate the role of IL-17 in the regulation of Listeria infection. more
CD2
CD2 molecule
total:12
Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1. 2012 to the paper
BD Pharmingen anti-CD2 monoclonal antibody was used to perform FACS in order to study novel HIV-1 capture mechanism. more
CD3
CD3d molecule
total:43
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
eBioscience anti-CD3 antibody was used to perform cell culture in order to study how gut microbiota regulate immunesystem. more
CD3E
CD3e molecule
total:20
Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1. 2012 to the paper
eBioscience anti-CD3 monoclonal antibody OKT3 was used to stimulate CD4+ T cell in order to study novel HIV-1 capture mechanism. more
CD3G
CD3g molecule
total:48
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD3 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
CD4
CD4 molecule
total:118
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Beckman coulter anti-CD4 PC5 was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
CD5
CD5 molecule
total:9
B cell receptor crosstalk: B cells express osteopontin through the combined action of the alternate and classical BCR signaling pathways. 2009 to the paper
BD Pharmingen anti-CD5 antibody was used to isolate B cell subpopulations in order to investigate the mechanism for BCR signaling pathway in the regulation of osteopontin production and secretion when B cells is exposed to IL-4. more
CD6
CD6 molecule
total:1
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
BD Biosciences anti-CD6 was used to perform flow cytometry in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway.
CD7
CD7 molecule
total:4
Intestinal T-cell and natural killer-cell lymphomas in Taiwan with special emphasis on 2 distinct cellular types: natural killer-like cytotoxic T cell and true natural killer cell. 2008 to the paper
Novocastra anti-CD7 antibody was used to perform immunohistochemistry in order to study the clinicopathological features of intestinal T-cell and natural killer-cell lymphomas in Taiwan. more
CD8A
CD8a molecule
total:96
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Becton Dickinson anti-CD8a antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
CD8B
CD8b molecule
total:5
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Becton Dickinson anti-CD8b antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
CD9
CD9 molecule
total:7
Expression and function of CD9 in melanoma cells. 2010 to the paper
Abcam anti-CD9 antibody was used to perform western blot in order to study the expression and function of CD9. more
CD14
CD14 molecule
total:80
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
AbDSerotec PE-Cy5-conjugated anti-CD14 antibody was used to perform flow cytometry in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
CD19
CD19 molecule
total:62
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Becton Dickinson anti-CD19 PE was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
CD27
CD27 molecule
total:12
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. 2011 to the paper
Beckman Coulter anti-CD27-APC-AlexaFluor700 was used to perform flow cytometry in order to show that HIV neutralizing antibodies evolved to recognize an invariant viral structure. more
CD28
CD28 molecule
total:25
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD28 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
CD33
CD33 molecule
total:12
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD33 was used in 1.5ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
CD34
CD34 molecule
total:79
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
AbDSerotec PE-Cy5-conjugated anti-CD34 antibody was used to perform flow cytometry in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
CD36
CD36 molecule
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
CD37
CD37 molecule
total:1
The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma. 2009 to the paper
Santa Cruz Biotechnology mouse anti-human CD37 was used to carry out immunostaining assays in order to investigate the role of PI3k/Akt pathway in macrophage-mediated antibody-dependent cell-mediated cytotoxicity.
CD38
CD38 molecule
total:21
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD38 was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
CD40
CD40 molecule
total:40
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-CD40 (C-20) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
CD40 ligand
total:13
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
Santa Cruz anti-CD40L antibody (1:200) was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
CD44
CD44 molecule (Indian blood group)
total:49
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Millipore rat anti-heparan sulfate proteoglycan monoclonal antibody was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models. more
CD46
CD46 molecule
total:8
CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells. 2010 to the paper
Hycult-Biotechnologies anti-CD46 mouse monoclonal antibody was used to perform western blot and flow cytometry in order to study the function of CD147/EMMPRIN as a receptor for measles virus on epithelial cells. more
CD47
CD47 molecule
total:4
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
BD Biosciences anti-CD47 was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
CD48
CD48 molecule
total:1
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Santa Cruz Biotechnology CD48 antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts.
CD52
CD52 molecule
total:2
Heterogeneous CD52 expression among hematologic neoplasms: implications for the use of alemtuzumab (CAMPATH-1H). 2006 to the paper
Serotec rat anti-human CD52 antibody with the same complementary determining regions as the humanized antibody (clone YTH34.5) was used in immunohistochemistry and flow cytometry to study heterogeneous CD52 expression among hematologic neoplasms and its implications for the use of alemtuzumab (CAMPATH-1H) more
CD55
CD55 molecule (Cromer blood group)
total:14
The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium. 2008 to the paper
Serotec monoclonal anti-CD55 antibody (67) was used in immunohistochemistry to determine whether the heterogeneous clinical response to tumour necrosis factor (TNF) alpha blocking therapy in rheumatoid arthritis (RA) can be predicted by TNFalpha expression in the synovium before initiation of treatment. more
CD58
CD58 molecule
total:6
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 to the paper
Immunotech/Coulter anti-CD58 antibody was used in flow cytometry immunophenotyping to study the function of fibromodulin which serves as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL) to enable the expansion of specific CD8+ autologous T lymphocytes more
CD59
CD59 molecule (CD59 blood group)
total:10
Activity after site-directed mutagenesis of CD59 on complement-mediated cytolysis. 2008 to the paper
Santa Cruz Biotechnology goat anti-human CD59 polyclonal antibody(Catalog #, sc-7077) was used to perform Enzyme-linked immunosorbent assays in order to demonstrate that residue W40 site of CD59 is important to its anti-complement activity. more
CD63
CD63 molecule
total:18
Acid sphingomyelinase activity triggers microparticle release from glial cells. 2009 to the paper
Santa Cruz Goat polyclonal anti-CD63/LAMP3 Ab (clone M-13, 1:50) was used in western blot in order to study the activation of acid sphingomyelinase in microparticle release from glial cells. more
CD68
CD68 molecule
total:83
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Dako FITC-labeled-anti-CD68 mAb was used to perform immunohistochemistry in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
CD69
CD69 molecule
total:15
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys. 2008 to the paper
BD Biosciences anti-CD69 antibody was used to perform flow cytometric analysis in order to study the determinants of the level of viremia in naturally SIV-infected SMs. more
CD70
CD70 molecule
total:1
CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production. 2010 to the paper
BD Biosciences anti-CD70 antibody was used in flow cytometry in order to investigate the role of CD27 in the regulation of IL2 production.
CD74
CD74 molecule
total:10
Identification of potential therapeutic targets in human head & neck squamous cell carcinoma. 2009 to the paper
Santa Cruz anti-CD74 antibody was used to perform immunohistochemistry in order to find out the potential therapeutic targets of the human head and neck squamous cell carcinoma. more
CD80
CD80 molecule
total:24
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Beckman anti-CD80 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
CD81
CD81 molecule
total:8
Fas death receptor enhances endocytic membrane traffic converging into the Golgi region. 2009 to the paper
BD Biosciences CD81 was used in immunocytochemistry in order to study the mechanism of endocytic membrane traffic converging into the golgi region more
CD83
CD83 molecule
total:20
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Beckman anti-CD83 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
CD86
CD86 molecule
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Beckman anti-CD86 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
CD93
CD93 molecule
total:1
ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. 2009 to the paper
eBioscience, C1qRp antibody was used for flow cytometry in order to clarify that ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling.
ADGRE5
adhesion G protein-coupled receptor E5
total:2
Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions. 2010 to the paper
Imgenex rabbit polyclonal CD97 antibody was used in western blot in order to investigate the function of CD97 in intestinal epithelial cells. more
CD99
CD99 molecule (Xg blood group)
total:4
The diagnostic value of SYT-SSX detected by reverse transcriptase-polymerase chain reaction (RT-PCR) and fluorescence in situ hybridization (FISH) for synovial sarcoma: a review and prospective study of 255 cases. 2008 to the paper
Zymed Laboratory anti-CD99 (O13) antibody was used to perform immunohistochemistry in order to study the diagnostic value of SYT-SSX detected by RT-PCR and FISH for synovial sarcoma. more
BY55
CD160 molecule
total:1
A novel activity for substance P: stimulation of peroxisome proliferator-activated receptor-gamma protein expression in human monocytes and macrophages. 2008 to the paper
Abcam rabbit polyclonal anti-NK1 receptor antibody (ab466) was used in western blot to evaluate the effects of SP on PPAR-gamma protein expression in monocytes and macrophages (MDMs: monocyte-derived macrophages) from healthy smokers and non-smokers.
CD163
CD163 molecule
total:11
Antimicrobial peptide hLF1-11 directs granulocyte-macrophage colony-stimulating factor-driven monocyte differentiation toward macrophages with enhanced recognition and clearance of pathogens. 2010 to the paper
BD Biosciences anti-CD163 monoclonal antibody was used to perform flow cytometry in order to study the antimicrobial peptide hLF1-11 affected human monocyte-macrophage differentiation. more
CD177
CD177 molecule
total:1
Tumorigenic potential of olfactory bulb-derived human adult neural stem cells associates with activation of TERT and NOTCH1. 2009 to the paper
Anti-HNA antibody from Chemicon was used for immunohistochemistry in order to study the relationship between the activation of TERT and NOTCH1 and tumorigenic potential of human adult neural stem cells from olfactory bulb.
CD200
CD200 molecule
total:2
Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration. 2007 to the paper
Cedarlane Laboratories CD200 antibody was used in immunohistochemistry at 1:200 dilution to study the role of CD200-CD200R pathway in axonal protection in the setting of inflammation-mediated neurodegeneration. more
CD244
CD244 molecule
total:2
ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. 2009 to the paper
eBioscience, CD244 antibody was used for flow cytometry in order to clarify that ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. more
CD247
CD247 molecule
total:68
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD3 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
CD274
CD274 molecule
total:4
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. 2009 to the paper
Biolegend anti-B7-H1 antibody was used in flow cytometry to harvest and stain infected cells in order to investigate the role of the JAK-STAT1 pathway in the regulation of the replication of HSV-1. more
E-cadherin
cadherin 1
total:129
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Invitrogen rat anti-E-Cadherin (ECCD-2; 13-1900) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
N-cadherin
cadherin 2
total:26
Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. 2010 to the paper
Abcam rabbit anti-N-cadherin antibody was used to carry out western blot analysis in order to investigate the role of forward trafficking of connexin 43 in gap junction coupling and ischemia-related cardiac arrhythmias therapy. more
VE cadherin
cadherin 5
total:19
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. 2009 to the paper
eBioscience anti-CD144 antibody was used in immunohistochemistry in order to demonstrate that vasculogenesis in human MM may develop from tumoral production of pleiotrophin, which induces the transdifferentiation of monocytes into VECs. more
CEACAM5
CEA cell adhesion molecule 5
total:5
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. 2010 to the paper
BD anti-pan-MCM antibody was used in western blot in order to investigate the mechanism of how the embryonic stem cells chromatin structure change was regulated by condensin complexes during mitotic progression. more
CEACAM6
CEA cell adhesion molecule 6
total:6
CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells. 2009 to the paper
Abcam mouse monoclonal CEACAM6 antibody was used to carry out western blot analysis in order to investigate the role for CEACAM6 in restricting adenovirus infection in cancer cells. more
CEACAM8
CEA cell adhesion molecule 8
total:3
Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. 2008 to the paper
Beckman Coulter fluorochrome-conjugated CD66b antibody was used in flow cytometry in order to determine whether high LPS levels are associated with increased monocyte activation and HAD more
CLEC4C
C-type lectin domain family 4 member C
total:1
Expression of the plasmacytoid dendritic cell marker BDCA-2 supports a spectrum of maturation among CD4+ CD56+ hematodermic neoplasms. 2006 to the paper
Cocalico Biologicals anti-BDCA-2 antibody was used in western blot and inmunohistochemistry to assess expression of BDCA-2 in CD4+CD56+ hematodermic neoplasms.
CLEC4M
C-type lectin domain family 4 member M
total:1
PPAR? controls Dectin-1 expression required for host antifungal defense against Candida albicans. 2010 to the paper
eBioscience anti-SIGNR1 antibody was used in flow cytometry in order to investigate the role of PPARgamma in the regulation dectin-1 expression and host antifungal defense.
CR1
complement C3b/C4b receptor 1 (Knops blood group)
total:2
Mesenchymal stem cell-mediated functional tooth regeneration in swine. 2006 to the paper
Pharmingen/BD Bioscience R-PE conjugated monoclonal anti-human CD35 antibody was used in human mesenchymal stem cell and in flow cytometry to study the role for mesenchymal stem cell in tooth regeneration in swine. more
CD21
complement C3d receptor 2
total:12
B cell receptor crosstalk: B cells express osteopontin through the combined action of the alternate and classical BCR signaling pathways. 2009 to the paper
BD Pharmingen anti-CD21 antibody was used to isolate B cell subpopulations in order to investigate the mechanism for BCR signaling pathway in the regulation of osteopontin production and secretion when B cells is exposed to IL-4. more
CSF1R
colony stimulating factor 1 receptor
total:7
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. 2006 to the paper
Upstate (Millipore) rabbit anti-human CSF-1 R polyclonal antibody(06-457)was used to perform mmunohistochemistry assays in order to investigate the molecular regulation mechanisms of Smad4 in the process of normal pancreas development and pancreatic ductal adenocarcinomas (PDAC) growth. more
CSF2RA
colony stimulating factor 2 receptor subunit alpha
total:7
Short-term heat exposure inhibits inflammation by abrogating recruitment of and nuclear factor-{kappa}B activation in neutrophils exposed to chemotactic cytokines. 2008 to the paper
Santa Cruz GM-CSF-receptor antibody was used in western blot in order to test the hypothesis that exposure of mice to fever-like temperatures abrogates neutrophil recruitment and NF-kappaB activation in a mouse model of skin inflammation more
CTLA 4
cytotoxic T-lymphocyte associated protein 4
total:6
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. 2011 to the paper
Santa Cruz anti-CTLA-4 antibody was used to perform immunocytochemistry in order to reveal the reason why CTLA-4 can inhibit CD28 stimulation. more
CXCR3
C-X-C motif chemokine receptor 3
total:11
A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells. 2008 to the paper
R&D Systems monoclonal anti-CXCR3 was used to perform blocking or activating experiments in order to show that a computational-based peptidomics can be used to identify peptides inhibiting the proliferation and migration of endothelial cells systematically. more
CXCR4
C-X-C motif chemokine receptor 4
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
CXCR6
C-X-C motif chemokine receptor 6
total:2
Role of Twist in head and neck carcinoma with lymph node metastasis. 2008 to the paper
R&D Systems anti-CXCR6 monoclonal antibody was used to perform immunohistochemistry in order to study the role of twist in metastasis of head and neck carcinoma. more
ACKR1
atypical chemokine receptor 1 (Duffy blood group)
DDR1
discoidin domain receptor tyrosine kinase 1
total:8
Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. 2009 to the paper
R&D Systems anti-NEP antibody was used in immunohistochemistry in order to investigate the role of neprilysin in the regulation of pulmonary vascular remodeling in response to chronic hypoxia. more
DPP4
dipeptidyl peptidase 4
total:6
Suppression of neuroblastoma growth by dipeptidyl peptidase IV: relevance of chemokine regulation and caspase activation. 2009 to the paper
Biomol anti-DPPIV antibody was used to perform immunohistochemistry in order to study the suppression of neuroblastoma growth performed by dipeptidyl peptidase IV. more
CD105
endoglin
total:13
Extended flow cytometry characterization of normal bone marrow progenitor cells by simultaneous detection of aldehyde dehydrogenase and early hematopoietic antigens: implication for erythroid differentiation studies. 2008 to the paper
R&D Systems anti-105 antibody was used to perform flow cytometry in order to study the new characterization about the dissection of normal bone marrow progenitor cells more
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
CD39
ectonucleoside triphosphate diphosphohydrolase 1
total:5
Vascular precursors in developing human retina. 2008 to the paper
Chemicon anti-CD39 antibody was used to perform immunohistochemistry in order to study vascular precursors of human retina. more
tissue factor
coagulation factor III, tissue factor
total:5
Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1. 2006 to the paper
BD Biosciences tissue factor antibody (CD142, clone number HTF-1) was used in western blot to detect its expression in culture medium and cell lysate from versican G3- or vector-transfected astrocytoma cell line U87 more
Fas
Fas cell surface death receptor
total:52
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Santa Cruz Biotechnology FAS antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
FasL
Fas ligand
total:12
HYAL1-v1, an alternatively spliced variant of HYAL1 hyaluronidase: a negative regulator of bladder cancer. 2006 to the paper
Santa Cruz Biotechnology anti-Fas-L antibody was used in western blot to study the role of HYAL1-v1 in regulating in bladder cancer growth, infiltration, and angiogenesis in transfected human HT1376 bladder cancer cells. more
CD23
Fc fragment of IgE receptor II
total:11
TRAF6 is required for generation of the B-1a B cell compartment as well as T cell-dependent and -independent humoral immune responses. 2009 to the paper
BD Pharmingen anti-CD23 antibody was used in flow cytometry in order to study the role for TRAF6 in T cell-dependent and T cell-independent humoral immune responses. more
CD64
Fc fragment of IgG receptor Ia
total:15
PPAR? controls Dectin-1 expression required for host antifungal defense against Candida albicans. 2010 to the paper
Serotec anti-F4/80 antibody was used in flow cytometry in order to investigate the role of PPARgamma in the regulation dectin-1 expression and host antifungal defense. more
CD32
Fc fragment of IgG receptor IIa
total:9
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-IgG antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
FCGR2B
Fc fragment of IgG receptor IIb
total:6
Loss of CD103+ intestinal dendritic cells during colonic inflammation. 2010 to the paper
BD Pharmingen CD32 antibody was used for FACS analysis in order to investigate possible differences in dendritic cells within intestinal tissue of mice before and after induction of colitis. more
CD16
Fc fragment of IgG receptor IIIa
total:42
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
AbDSerotec PE-Cy5-conjugated anti-CD16 antibody was used to perform flow cytometry in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
FCGR3B
Fc fragment of IgG receptor IIIb
total:3
Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. 2008 to the paper
Beckman Coulter fluorochrome-conjugated CD16b antibody was used in flow cytometry in order to determine whether high LPS levels are associated with increased monocyte activation and HAD more
FCRL5
Fc receptor like 5
total:1
Immunoglobulin superfamily receptor translocation associated 2 protein on lymphoma cell lines and hairy cell leukemia cells detected by novel monoclonal antibodies. 2005 to the paper
Ira Pastan (NIH) IRTA2 antibody was used in western blot to study the expression of the IRTA2 gene product.
FGFR1
fibroblast growth factor receptor 1
total:17
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Biosource International anti-FGFR-1 (pYpY653/654) antibodies were used to perform western blot and ELISA analyses in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
FGFR2
fibroblast growth factor receptor 2
total:9
Endothelial function of von Hippel-Lindau tumor suppressor gene: control of fibroblast growth factor receptor signaling. 2008 to the paper
Santa Cruz rabbit polyclonal anti-FGFR2 was used to perform western blot in order to show that VHL tumor supppressor gene has endothelial function through fibroblast growth factor receptor signaling. more
FGFR3
fibroblast growth factor receptor 3
total:7
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Santa Cruz mouse anti-FGFR3 was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
FGFR4
fibroblast growth factor receptor 4
total:5
Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-FGFR4 antibody was used to carry out western blot analysis in order to investigate whether FGFR4 plays a role in promoting the progression of hepatocellular carcinoma. more
FLT3
fms related receptor tyrosine kinase 3
total:6
Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation. 2006 to the paper
Santa Cruz Biotechnology anti-FLT3(S18) antibody was used to perform western blot in order to study the mechanism of the decreased proliferation of acute myeloid leukemia (AML) cells treated with arsenic trioxide. more
CD15
fucosyltransferase 4
total:16
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD15 was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
GP5
glycoprotein V platelet
total:3
Renewal of mural thrombus releases plasma markers and is involved in aortic abdominal aneurysm evolution. 2006 to the paper
Diagnostica Stago antibody against soluble glycoprotein V (sGPV) was used in ELISA to measure sGPV levels in plasma samples and eluates obtained from patients more
CRTH2
prostaglandin D2 receptor 2
total:1
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. 2009 to the paper
Miltenyi Biotec anti-CRTH2-PE antibody was used to carry out flow cytometry analysis in order to investigate the mechanism for IL-33 in promoting allergic inflammation.
Glycophorin A
glycophorin A (MNS blood group)
total:16
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Beckman-coulter PE-conjugated anti-Glycophorin A was used to perform flow cytometry in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
glycophorin C
glycophorin C (Gerbich blood group)
total:2
Functional consequences of interactions between human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells. 2008 to the paper
BD Pharmingen anti-CD236 antibody was used in flow cytometry to deplete CD236+ T cells. more
ICAM-1
intercellular adhesion molecule 1
total:30
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. 2011 to the paper
R&D systems anti-ICAM-1 antibody was used to perform immunocytochemistry in order to study the remodelling of cortical actin at natural killer cell immune synapses. more
ICAM2
intercellular adhesion molecule 2
total:2
ICAM-2 expression mediates a membrane-actin link, confers a nonmetastatic phenotype and reflects favorable tumor stage or histology in neuroblastoma. 2008 to the paper
R&D Systems anti-ICAM-2 antibody was used for western blot in order to investigate the role of ICAM-2 in the mediation of membrane-actin link in neuroblastoma. more
intercellular adhesion molecule 3
total:8
Binding of the Streptococcus gordonii DL1 surface protein Hsa to the host cell membrane glycoproteins CD11b, CD43, and CD50. 2008 to the paper
R&D Systems anti-CD50 (1:250) antibody was used in western blotting in order to investigate the binding of the Streptococcus gordonii DL1 surface protein Hsa to the host cell membrane glycoproteins CD11b, CD43, and CD50 more
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ICOS
inducible T cell costimulator
total:3
Lack of disease specificity limits the usefulness of in vitro costimulation in HIV- and HCV-infected patients. 2008 to the paper
eBioscience agonistic anti-ICOS antibody (final concentration of 1 ug/mL) was used to treat cells in order to test the effects of IL-7/IL-15, IFN-alpha, anti-ICOS, and anti-CD28 on antigen-specific T cell responses in patients infected with HCV or HIV more
IFITM1
interferon induced transmembrane protein 1
total:1
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Proteintech Group anti-IFITM1 antibody was used to perform immunoblot in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers.
IFNGR1
interferon gamma receptor 1
total:5
Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling. 2008 to the paper
BD Biosciences anti-CD119 monoclonal antibody was used to perform flow cytometry in order to study the role of human BM-derived MSCs expressed TLR3 and TLR4 in inhibiting their T-Cell modulatory activity. more
IGF-IR
insulin like growth factor 1 receptor
total:40
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Santa Cruz Biotechnology PE-conjugated anti-IGF-1R antibody was used in flow cytometry to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
CI-MPR
insulin like growth factor 2 receptor
total:7
Vaccinia virus p37 interacts with host proteins associated with LE-derived transport vesicle biogenesis.. 2009 to the paper
Affinity BioReagents CI-MPR was used as primary antibody in immunofluorecent staining in order to study the interaction between the vaccinia virus p37 and host proteins associated with LE-derived transport vesicle biogenesis. more
IL1R1
interleukin 1 receptor type 1
total:5
Control of chemokine gradients by the retinal pigment epithelium. 2008 to the paper
Abcam IL-1R1 antibody was used in western blot in order to examine the physiological responses of human fetal retinal pigment epithelia (hfRPE) after polarized activation of proinflammatory cytokine receptors in vitro more
IL1R2
interleukin 1 receptor type 2
total:2
Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology. 2007 to the paper
R&D Systems polyclonal goat anti-human IL1R2 antibody was used in western blot and immunocytochemistry to evaluate the role of IL1R2 deficiency in endometriosis pathophysiology. more
CD25
interleukin 2 receptor subunit alpha
total:49
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. 2009 to the paper
eBioscience anti-CD25 antibody was used in flow cytometry in order to investigate the role of dendritic cells in the regulation of spontaneous fatal autoimmunity. more
IL2RB
interleukin 2 receptor subunit beta
total:5
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
BD Biosciences PE anti-CD122 monoclonal antibody was used to perform flow cytometry to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
IL2RG
interleukin 2 receptor subunit gamma
total:5
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. 2008 to the paper
BD Bioscience CD132 antibody was used to perform flow cytometry in order to identify that IL-13 is an effector cytokine and IL-4 is an immunoregulatory cytokine. more
CD123
interleukin 3 receptor subunit alpha
total:12
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD123 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
IL-6R
interleukin 6 receptor
total:10
Intracellular signaling mechanisms and activities of human herpesvirus 8 interleukin-6. 2009 to the paper
Santa Cruz Biotechnology anti-gp80 antibody was used in western blot in order to study the role of vIL-6 in the growth and survival of cells latently infected with HHV-8. more
gp130
interleukin 6 signal transducer
total:12
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway. 2010 to the paper
Santa Cruz Biotechnology anti-GP130 polyclonal antibody was used to perform immunohistochemistry in order to study the modulation of IL11 expression by PROK1 via PROKR1 and the calcineurin/NFAT signalling pathway. more
IL7R
interleukin 7 receptor
total:6
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Immunotech anti-CDw127 was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
CXCR1
C-X-C motif chemokine receptor 1
total:7
Short-term heat exposure inhibits inflammation by abrogating recruitment of and nuclear factor-{kappa}B activation in neutrophils exposed to chemotactic cytokines. 2008 to the paper
Santa Cruz IL-8-receptor antibody was used in western blot in order to test the hypothesis that exposure of mice to fever-like temperatures abrogates neutrophil recruitment and NF-kappaB activation in a mouse model of skin inflammation more
CXCR2
C-X-C motif chemokine receptor 2
total:9
The role of the chemokines MCP-1, GRO-alpha, IL-8 and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques. 2008 to the paper
R&D Systems CXCR2 IgG2a antbody was used to inhibit cell adhesion in order to study the role of the chemokines MCP-1, GRO-alpha, IL-8, and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques more
IL10RB
interleukin 10 receptor subunit beta
total:1
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-10R2 mAb was used to perform western blot in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26.
IL13RA1
interleukin 13 receptor subunit alpha 1
total:3
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. 2008 to the paper
R&D Systems anti-IL-13Ralpha1 antibody was used for flow cytometry to elucidated the role of IL-4 and IL-13 in regulates relative cytokine sensitivity. more
IL13RA2
interleukin 13 receptor subunit alpha 2
total:4
Expression of glioma-associated antigens in pediatric brain stem and non-brain stem gliomas. 2008 to the paper
R&D goat anti-human IL-13Ralpha2 polyclonal antibody (15 ug/ml) was used in immunohistochemistry in order to investigate the protein expression of three glioma-associated antigens (GAAs) in pediatric brain stem glioma (BSG) and non-brain stem glioma (NBSG) cases more
IL17RA
interleukin 17 receptor A
total:3
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. 2011 to the paper
R&D Systems PE-anti-human IL-17RA was used to perform flow cytometry in order to show that IL-17 immunodeficiency could lead to CMCD. more
IL18R1
interleukin 18 receptor 1
total:2
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. 2009 to the paper
R&D Systems anti-IL-18R-PE antibody was used to carry out flow cytometry analysis in order to investigate the mechanism for IL-33 in promoting allergic inflammation. more
insulin receptor
total:22
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti subunit of insulin receptors (IR) antibody was used in western blot and immunocytochemistry to test the hypothesis that insulin signaling provides a physiological defense mechanism against the synaptotoxicity of Abeta-derived diffusible ligands. more
ITGA1
integrin subunit alpha 1
total:11
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha1 antibody (clone FB12) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
integrin alpha2
integrin subunit alpha 2
total:15
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha2 antibody (clone P1E6) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
CD41
integrin subunit alpha 2b
total:13
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD41 was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
integrin alpha3
integrin subunit alpha 3
total:16
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
Millipore anti-integrin alpha 3 antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
ITGA4
integrin subunit alpha 4
total:7
Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells. 2009 to the paper
eBioscience antibodies against alpha4beta1 were used in immunohistochemistry to investigate MuPAR and plasmin in the regulation of the proliferation, marrow pool size, homing, engraftment, and mobilization of HSPCs and HSCs. more
integrin alpha5
integrin subunit alpha 5
total:30
The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis. 2008 to the paper
Chemicon monoclonal anti-alpha5 was used to perform blocking experiments in order to show that integrins could interact with CXCL4 and play a role in angiogenesis. more
ITGA6
integrin subunit alpha 6
total:20
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD49f-PE antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
ITGAE
integrin subunit alpha E
total:2
Loss of CD103+ intestinal dendritic cells during colonic inflammation. 2010 to the paper
BD Pharmingen CD103 antibody was used for FACS analysis in order to investigate possible differences in dendritic cells within intestinal tissue of mice before and after induction of colitis. more
LFA-1
integrin subunit alpha L
total:14
Altered gene expression in early atherosclerosis is blocked by low level apolipoprotein E. 2008 to the paper
eBioscience CD11a antibody was used in immunohistochemistry in order to study the linkage between changes of adhesion molecules/cofactors and atherosclerosis more
CD11b
integrin subunit alpha M
total:46
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Beckman-coulter PE-conjugated anti-CD11b was used to perform flow cytometry in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
integrin alpha v
integrin subunit alpha V
total:24
TGFBI expression is associated with a better response to chemotherapy in NSCLC. 2010 to the paper
Chemicon Interational anti-integrin alphavbeta3 monoclonal was used to perform flow cytometry in order to determine if this integrin influences TGFBI-mediated NSCLC cell susceptibility to chemotherapy. more
CD11c
integrin subunit alpha X
total:25
Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1. 2012 to the paper
BioLegend anti-CD11c monoclonal antibody was used to perform FACS in order to study novel HIV-1 capture mechanism. more
beta1 integrin
integrin subunit beta 1
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
CD18
integrin subunit beta 2
total:23
CBFbeta is critical for AML1-ETO and TEL-AML1 activity. 2009 to the paper
eBioscience allophycocyanin (APC), phycoerythrin (PE), or PerCPcy5.5 conjugated anti Mac-1 (clone M1/70) antibody was used in flow cytometry in order to determine whether CBFbeta is required for AML1-ETO and TEL-AML1 activity more
integrin beta3
integrin subunit beta 3
total:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal integrin beta3 antibody (1:1000) was used in western blot in order to study the role of activated state of p42/44 and p38 in MMP-13 expression. more
ITGB4
integrin subunit beta 4
total:12
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-ITGB4 antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
JAGGED1
jagged canonical Notch ligand 1
total:12
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
R&D Systems anti-Jagged1 antibody was used to perform flow cytometry in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
VEGFR-2
kinase insert domain receptor
total:35
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling.. 2010 to the paper
Santa Cruz anti-Flk-1 antibody was used to perform immunoprecipitation in order to reveal the critical role of prorenin receptor and vacuolar H+-ATPase-mediated acidification in Wnt signaling. more
KEL
Kell metallo-endopeptidase (Kell blood group)
KIR2DL1
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
KIR2DL2
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2
KIR2DL4
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
KIR2DL5A
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A
KIR2DS1
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1
KIR2DS4
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4
KIR2DS5
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5
KIR3DL1
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
KIR3DL2
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2
KIR3DL3
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
C-kit
KIT proto-oncogene, receptor tyrosine kinase
total:42
Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. 2012 to the paper
NeoMarkers mouse anti-human CD117 monoclonal antibody was used to perform immunohistochemistry in order to analyze the cellular origin of adult functional blood vessels. more
KLRB1
killer cell lectin like receptor B1
total:6
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD161 was used in 5ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
NKG2A
killer cell lectin like receptor C1
total:1
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. 2011 to the paper
R&D systems anti-NKG2A antibody was used to perform immunocytochemistry in order to study the remodelling of cortical actin at natural killer cell immune synapses.
NKG2D
killer cell lectin like receptor K1
total:5
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. 2010 to the paper
BD Pharmingen monoclonal anti-NKG2D-allophycocyanin antibody was used to perform flow cytometry in order to show multiple CD3 Zeta-dependent receptor functions can be impaired simultaneously by pathological NKG2D ligand expression. more
LAG3
lymphocyte activating 3
total:1
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Becton Dickinson anti-LAG3 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem.
LAIR1
leukocyte associated immunoglobulin like receptor 1
LAIR2
leukocyte associated immunoglobulin like receptor 2
LAMP-1
lysosomal associated membrane protein 1
total:47
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
BD Biosciences anti-Lamp-1 antibody was used to perform western blot in order to study the diffrent trafficking mechanisms of endosomal TLRs mediated by UNC93B1. more
Lamp-2
lysosomal associated membrane protein 2
total:24
Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. 2012 to the paper
Abcam rabbit anti-LAMP2 was used to perform immunocytochemistry in order to show that ciliogenesis was regulated by an evolutionarily assembled cis-regulatory module more
LAMP3
lysosomal associated membrane protein 3
total:1
Depletion of alveolar glycogen corresponds with immunohistochemical development of CD208 antigen expression in perinatal lamb lung. 2006 to the paper
Beckman Coulter mouse monoclonal anti-CD208 antibody (1:5000) was used in immunohistochemistry to demonstrate that CD208 antigen expression may serve as a marker for pneumocyte maturation in the developing fetal lung.
leptin receptor
total:9
leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. 2007 to the paper
Santa Cruz Biotechnology OB-R antibodies (C-20: specific for long form of leptin receptor, H-300: for both long and short form of leptin receptor, mouse monoclonal B-3: for both long and short forms of leptin receptor) were used in immunoprecipitation (C-20 and H-300) and western blot (B-3) to study the recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3 by leptin and its stimulation of breast cancer cells. more
LIFR
LIF receptor subunit alpha
total:7
Interleukin-6 and neural stem cells: more than gliogenesis. 2009 to the paper
Santa Cruz rabbit polyclonal anti-LIFR antibody was used to detect LIFR in western blot in order to demonstrate that the MAPK/CREB cascade and the STAT-3 signaling pathway mediate H-IL-6-activated neurogenesis and gliogenesis more
ILT7
leukocyte immunoglobulin like receptor A4
LIR9
leukocyte immunoglobulin like receptor A5
LILRA6
leukocyte immunoglobulin like receptor A6
LILRB1
leukocyte immunoglobulin like receptor B1
total:2
Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function. 2006 to the paper
Upstate CD85j antibody was used in western blot to study the association of ILT2 and murine MHC class I molecules in vivo. more
MCAM
melanoma cell adhesion molecule
total:4
Hypoxia regulates cross-talk between Syk and Lck leading to breast cancer progression and angiogenesis. 2006 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-MelCAM antibody and mouse monoclonal anti-MelCAM antibody were used in human MCF-7 cells and paraffin sections from human tumor, and which were used in western blot and immunohistochemistry, to study the role for the effect of hypoxia on cross-talk between Syk and Lck in breast cancer progression and angiogenesis. more
CD10
membrane metalloendopeptidase
total:22
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD10 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
MRC1
mannose receptor C-type 1
total:2
Antimicrobial peptide hLF1-11 directs granulocyte-macrophage colony-stimulating factor-driven monocyte differentiation toward macrophages with enhanced recognition and clearance of pathogens. 2010 to the paper
BD Biosciences anti-CD206 monoclonal antibody was used to perform flow cytometry in order to study the antimicrobial peptide hLF1-11 affected human monocyte-macrophage differentiation. more
CD20
membrane spanning 4-domains A1
total:54
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD20 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
RON
macrophage stimulating 1 receptor
total:4
The RON receptor tyrosine kinase promotes MSP-independent cell spreading and survival in breast epithelial cells. 2009 to the paper
Santa Cruz anti-RON antibody was used to perform western blot in order to study the oncogenic behavior of the RON receptor tyrosine kinase in breast epithelial cells. more
MUC1
mucin 1, cell surface associated
total:28
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Lab Vision anti-MUC1-C antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
CD56
neural cell adhesion molecule 1
total:56
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD56 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
NCR1
natural cytotoxicity triggering receptor 1
total:3
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. 2010 to the paper
Beckman Coulter monoclonal anti-NKp46-PE antibody was used to perform flow cytometry in order to show multiple CD3 Zeta-dependent receptor functions were impaired simultaneously by pathological NKG2D ligand expression. more
NCR2
natural cytotoxicity triggering receptor 2
NCR3
natural cytotoxicity triggering receptor 3
total:2
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. 2010 to the paper
Beckman Coulter monoclonal anti-NKp30-PE antibody was used to perform flow cytometry in order to show multiple CD3 Zeta-dependent receptor functions were impaired simultaneously by pathological NKG2D ligand expression. more
p75NTR
nerve growth factor receptor
total:17
Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line. 2008 to the paper
Novus Biologicals anti-p75NTR antibody was used to perform immunocytochemistry in order to show that cellular phenotype can be changed after exposure to acid and bile salt in Barrett's epithelial cell line. more
neuropilin 1
total:7
Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer xenografts. 2007 to the paper
Santa Cruz Biotechnology NRP-1 antibody was used in western blot and immunohistochemistry to study the role of placenta growth factor in malignancy. more
CD73
5'-nucleotidase ecto
total:12
Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. 2010 to the paper
Hycult Biotechnology mouse anti-human CD73 (1:50) antibody was used to perform immunohistochemistry in order to show that the adenosine metabolism and signaling in the lungs of patients with COPD and IPF are altered. more
PDCD1
programmed cell death 1
total:1
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. 2008 to the paper
Ebioscience anti-PD-1 antibody (J116 clone) was used in immunohistochemistry to study the role for FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes in theraping high-risk breast cancer patients paraffin section from human tumor.
PDCD1LG2
programmed cell death 1 ligand 2
total:3
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. 2009 to the paper
Biolegend B7-DC antibody was used in flow cytometry to harvest and stain infected cells in order to investigate the role of the JAK-STAT1 pathway in the regulation of the replication of HSV-1. more
PDGFR alpha
platelet derived growth factor receptor alpha
total:14
PDGFRalpha/beta expression correlates with the metastatic behavior of human colorectal cancer: a possible rationale for a molecular targeting strategy. 2008 to the paper
Santa Cruz Biotechnology anti-PDGFRA antibody was used to perform Western Blot and immunohistochemistry in order to prove that the metastatic behavior of human colorectal cancer correlates with PDGFRalpha/beta expression. more
PDGFR beta
platelet derived growth factor receptor beta
total:27
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy. 2009 to the paper
Abgent anti-p-PDGFR Tyr579 antibody was used in immunohistochemistry in order to investigate the mechanism of how Akt mediates sterol regulatory element-binding protein 1 (SREBP-1) cleavage induced by EGFR. more
PECAM 1
platelet and endothelial cell adhesion molecule 1
total:125
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Millipore anti-mouse CD31 antibody was used to perform immunohistochemistry in order to study the inhibition of antifungal drug thiabendazole to tumor growth in a mouse xenograft model. more
uPAR
plasminogen activator, urokinase receptor
total:13
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 to the paper
Abcam rabbit anti-uPAR antibody was used to carry out immunofluorescence assays in order to investigate the association for increased expression of urokinase plasminogen activator and megakaryocyte differentiation in Quebec platelet disorder. more
prion protein
total:17
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Chemicon anti-Prion Protein was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
PROCR
protein C receptor
total:4
Endothelial protein C receptor is overexpressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes. 2007 to the paper
R&D systems goat antihuman EPCR antibody was used in immunohistochemistry to determine the major cell type (s) that EPCR is associated with and whether EPCR functions to mediate the effects of activated protein C (APC) on these cells. more
CD133
prominin 1
total:19
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. 2009 to the paper
Abcam polyclonal anti-CD133 antibody was used for western blot in order to identify the role of MT1-MMP for the regulation of COX-2 expression in CD133 (+) U87 glioblastoma cells. more
PSG1
pregnancy specific beta-1-glycoprotein 1
total:1
Expression of Sp1 and KLF6 in the developing human cornea. 2007 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-Sp1 antibody (PEP2) was used in immunohistochemistry to study the temporal and spatial expression of Sp1 and Kr ppel-like factor 6 (KLF6) in the cornea in fetal and adult human eyes.
CD45
protein tyrosine phosphatase receptor type C
total:123
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Invitrogen biotin-labeled anti-CD45 mAb was used for cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
NECTIN1
nectin cell adhesion molecule 1
total:3
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
R&D Systems goat anti-human PVRL1 antibody was used to perform cell culture and western blot in order to investigate the role of PVRL4 in tumor progression. more
NECTIN3
nectin cell adhesion molecule 3
total:1
A double mutation in glycoprotein gB compensates for ineffective gD-dependent initiation of herpes simplex virus type 1 infection. 2010 to the paper
R&D anti-nectin-3 monoclonal antibody was used to pretreat CHO-K1 cells in vitro to investigate the compensation by mutated-gB for initiation of HSV-1 Infection.
RHD
Rh blood group D antigen
total:2
CAPERalpha is a novel Rel-TAD-interacting factor that inhibits lymphocyte transformation by the potent Rel/NF-kappaB oncoprotein v-Rel. 2008 to the paper
Santa-Cruz Biotechnology anti-RHD antibody (SC-6955) was used in western blot to study the effect of the interaction of CAPERalpha with Rel-TAD on modulating lymphocyte transformation. more
syndecan
syndecan 1
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more
E-selectin
selectin E
total:5
The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium. 2008 to the paper
R&D monoclonal anti-E-selectin antibody (BBIG-E4) was used in immunohistochemistry to determine whether the heterogeneous clinical response to tumour necrosis factor (TNF) alpha blocking therapy in rheumatoid arthritis (RA) can be predicted by TNFalpha expression in the synovium before initiation of treatment. more
CD62L
selectin L
total:14
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 2010 to the paper
BD Biosciences anti-CD62L antibody was used in flow cytometry in order to investigate the roles of Fas ligand and TRAIL in the regulation of murine thymic graft-versus-host disease. more
P-selectin
selectin P
total:8
Effect of tumour necrosis factor-alpha receptor 1 genetic deletion on carrageenan-induced acute inflammation: a comparison with etanercept. 2008 to the paper
Santa Cruz Biotechnology anti-P-selectin antibody was used in immunohistochemistry at 1:500 in order to evaluate an in vivo role of TNF-alphaR1 on the pathogenesis of inflammatory diseases more
SELPLG
selectin P ligand
total:5
Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function. 2008 to the paper
BD Bioscience anti-PSGL-1 antibody (PL1) was used in blocking or activating expriments to study the effect of the role for Anaplasma phagocytophilum in increasing cathepsin L activity on neutrophil function. more
SEMA7A
semaphorin 7A (John Milton Hagen blood group)
total:1
Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis. 2007 to the paper
R&D Systems SEMA 7A (AF1835) antibody was used in western blot to study the role of semaphorin 7A in TGF-beta1-induced pulmonary fibrosis
SIGLEC6
sialic acid binding Ig like lectin 6
total:1
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A. 2009 to the paper
Abcam anti-sialic acid binding Ig-like lectin 6 polyclonal antibody was used for immunohistochemistry in order to study the gene expression profiling of pulmonary mucosa-associated lymphoid tissue lymphoma and identify new biologic insights with potential diagnostic and therapeutic applications.
CD150
signaling lymphocytic activation molecule family member 1
total:5
CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells. 2010 to the paper
Biolegend anti-SLAM mouse monoclonal antibody was used to perform western blot and flow cytometry in order to study the function of CD147/EMMPRIN as a receptor for measles virus on epithelial cells. more
AE1
solute carrier family 4 member 1 (Diego blood group)
total:5
Adenomatoid tumour of the liver. 2008 to the paper
Labvision anti-AE1 antibody was used to perform immunohistochemistry in order to study the adenomatoid tumour of the liver. more
CD43
sialophorin
total:10
Fas death receptor enhances endocytic membrane traffic converging into the Golgi region. 2009 to the paper
Santa Cruz Biotechnology CD43 was used in immunocytochemistry in order to study the mechanism of endocytic membrane traffic converging into the golgi region more
EPCAM
epithelial cell adhesion molecule
total:11
Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. 2010 to the paper
BD Biosciences anti-EpCam antibody was used to perform purification of primary lung tumor cells in order to study whether TLR7 and TLR8 expressed by human lung cancer cells induced cell survival and chemoresistance. more
tie-2
TEK receptor tyrosine kinase
total:11
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-Flk-1 antibody was used in western blot in order to demonstrate that vasculogenesis in human MM may develop from tumoral production of pleiotrophin, which induces the transdifferentiation of monocytes into VECs. more
transferrin receptor
total:70
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-CD71-APC antibody was used to perform flow cytometry in order to study the different trafficking mechanisms of endosomal Toll-like receptors mediated by UNC93B1. more
thrombomodulin
total:8
IL-32-dependent effects of IL-1beta on endothelial cell functions. 2009 to the paper
R&Dsystems anti-human CD141/TM antibody was used in western blot to study the role for IL-32 in the effect of IL-1 on endothelial cell functions. more
CD90
Thy-1 cell surface antigen
total:19
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Becton Dickinson anti-Thy1 was used in 40 ul/mL to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
TLR1
toll like receptor 1
total:3
Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis.. 2008 to the paper
Santa Cruz Biotechnology rabbit polyclonal TLR1 antibody (2 ug/ml) was used in western blot in order to study the role of toll-Like receptors in the pathogenesis of lyme neuroborreliosis more
TLR2
toll like receptor 2
total:22
Inflammatory role of Toll-like receptors in human and murine adipose tissue. 2010 to the paper
Hycult Biotechnologies monoclonal anti-TLR2 was used to perform ELISA in order to show that Toll-like receptors in human and murine adipose tissue participate omental adipose tissue-related inflammation. more
TLR3
toll like receptor 3
total:9
Expression of Toll-like receptors in verruca and molluscum contagiosum. 2008 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human TLR3 was used in immunohistochemistry to study the expression of toll-like receptors in verruca and molluscum contagiosum in cryostat sections from human skin. more
TLR4
toll like receptor 4
total:37
Role of Toll-like receptor 4 and human defensin 5 in primary endocervical epithelial cells. 2010 to the paper
R&D mouse monoclonal anti-TLR4 antibody was used to perform western blot in order to study the immune defence role of TLR4 and HD5 in primary endocervical epithelial cells. more
TLR9
toll like receptor 9
total:6
Expression of Toll-like receptors in verruca and molluscum contagiosum. 2008 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human TLR9 was used in immunohistochemistry to study the expression of toll-like receptors in verruca and molluscum contagiosum in cryostat sections from human skin. more
TNFR1
TNF receptor superfamily member 1A
total:23
Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation. 2009 to the paper
Santa Cruz anti-TNFR1 antibody was used to perform western blot in order to study the mechanism that TRAF2 inhibits stress-induced cell death. more
TNFR2
TNF receptor superfamily member 1B
total:14
Control of chemokine gradients by the retinal pigment epithelium. 2008 to the paper
Stressgen Bioreagents TNFR2 antibody was used in western blot in order to examine the physiological responses of human fetal retinal pigment epithelia (hfRPE) after polarized activation of proinflammatory cytokine receptors in vitro more
CD30
TNF receptor superfamily member 8
total:10
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 to the paper
Immunotech/Coulter anti-CD30 antibody was used in flow cytometry immunophenotyping to study the function of fibromodulin which serves as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL) to enable the expansion of specific CD8+ autologous T lymphocytes more
4 1BB
TNF receptor superfamily member 9
total:3
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. 2008 to the paper
Santa Cruz Biotechnology polyclonal anti-CD137/4-1 BB(N-16) antibody was used to perform flow cytometric analysis in order to study the important role of CD30 signaling in Hodgkin's and anaplastic large cell lymphoma (ALCL) cell lines. more
DR4
TNF receptor superfamily member 10a
total:10
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. 2008 to the paper
Diaclone mouse monoclonal anti-DR4 antibody (B-N28) was used to perform western blot in order to study the function of the natural product honokiol. more
DR5
TNF receptor superfamily member 10b
total:15
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 2010 to the paper
eBioscience rabbit polyclonal anti-DR5 antibody was used in flow cytometry in order to investigate the roles of Fas ligand and TRAIL in the regulation of murine thymic graft-versus-host disease. more
TNFRSF10C
TNF receptor superfamily member 10c
total:1
Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway. 2005 to the paper
Alexis anti-DcR1 (HS301) antibody was used in flow cytometry to study the biological function of TRAIL induced apoptosis in human colon cells.
TNFRSF10D
TNF receptor superfamily member 10d
total:3
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation. 2010 to the paper
Stressgen DcR2 antibody was used in immunohistochemistry in order to show the importance of protection of the ATM-mediated DDR-p53 signaling pathway for breast cancer prevention. more
TNFRSF11A
TNF receptor superfamily member 11a
total:2
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Abcam anti-RANK monoclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
TNFRSF12A
TNF receptor superfamily member 12A
total:1
Regulation of tumor necrosis factor-like weak inducer of apoptosis receptor protein (TWEAKR) expression by Kaposi's sarcoma-associated herpesvirus microRNA prevents TWEAK-induced apoptosis and inflammatory cytokine expression. 2010 to the paper
Cell Signaling anti-TWEAKR antibody was used to perform western blot in order to study the mechanism by which KSHV miRNA prevented TWEAK-induced apoptosis and proinflammatory response.
TACI
TNF receptor superfamily member 13B
total:3
Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes. 2009 to the paper
Peprotech EC biotinylated polyclonal goat anti-human TACI antibody was used to carry out flow cytometry analysis in order to evaluate the genetic, immunologic, and clinical condition of patients with different TNFRSF13B variants. more
BCMA
TNF receptor superfamily member 17
total:2
Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor. 2005 to the paper
R&D Systems anti BCMA antibody was used in western blot and flow cytometry to study graft-versus-tumor response in patients with multiple myeloma more
TRAIL
TNF superfamily member 10
total:6
Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells. 2005 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-TRAIL antibody was used in western blot to investigate the role of human BVR in sodium arsenite (As) mediated induction of HO-1 and in cytoprotection against apoptosis by small interference RNA-mediated gene silencing. more
RANKL
TNF superfamily member 11
total:7
Differential expression of RANK, RANK-L, and osteoprotegerin by synovial fluid neutrophils from patients with rheumatoid arthritis and by healthy human blood neutrophils. 2007 to the paper
R&D Systems monoclonal anti-human OPG antibody was used in elisa to study differential expression of RANK, RANK-L, and osteoprotegerin from patients with rheumatoid arthritis. more
TNFSF13
TNF superfamily member 13
total:2
Expression of TNF-superfamily members BAFF and APRIL in breast cancer: immunohistochemical study in 52 invasive ductal breast carcinomas. 2008 to the paper
Alexis mouse monoclonal anti-APRIL (hAprily-8) antibody (ALX-804-149) was used in immunohistochemistry to study the expression of BAFF and APRIL in breast cancer in paraffin sections from human tumor. more
TNFSF13B
TNF superfamily member 13b
total:6
Expression of TNF-superfamily members BAFF and APRIL in breast cancer: immunohistochemical study in 52 invasive ductal breast carcinomas. 2008 to the paper
Alexis monoclonal anti-BAFF antibody (804-131-C100, Buffy-2 clone) was used in immunohistochemistry to study the expression of BAFF and APRIL in breast cancer in paraffin sections from human tumor. more
VCAM-1
vascular cell adhesion molecule 1
total:19
The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. 2009 to the paper
Immunotech anti-VCAM-1 antibody was used in blocking or activating expriments to study the role for prostate specific membrane antigen in regulating the expression of IL-6 and CCL5 in prostate tumour cells. more