Assembly of the pre-replicative complex
gene
reagent
sample publication
sample review
CDC6
cell division cycle 6
total:9
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdc6 antibody was used to perform immunoprecipitation in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
CDT1
chromatin licensing and DNA replication factor 1
total:3
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Proteintech Group Cdt1 antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
geminin
geminin DNA replication inhibitor
total:5
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 to the paper
Santa Cruz anti-Geminin was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction more
MCM2
minichromosome maintenance complex component 2
total:8
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 to the paper
BD Biosciences antibody to total Mcm2 was used in western blot to examine the levels of total Mcm2 in HeLa cells. more
MCM3
minichromosome maintenance complex component 3
total:5
Orc1 controls centriole and centrosome copy number in human cells. 2009 to the paper
Santa Cruz Biotechnology rabbit pAb anti-MCM3 antibody was used for western blot in order to demonstrate that the copy numbers of centriole and centrosome were regulated by Orc1 in human cells. more
MCM4
minichromosome maintenance complex component 4
total:1
The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. 2010 to the paper
Acbam anti-MCM4 antibody was used for western blot in order to investigate the role of the ETG1 in the regulation of endogenous DNA stress.
MCM5
minichromosome maintenance complex component 5
total:2
The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation. 2005 to the paper
Bethyl Laboratories MCM5 antibody was used in ChIP assay to study the role of DNA replication factor MCM5 in Stat1-mediated transcriptional activation more
MCM6
minichromosome maintenance complex component 6
total:2
The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. 2010 to the paper
Acbam anti-MCM6 antibody was used for western blot in order to investigate the role of ETG1 in the regulation of endogenous DNA stress. more
MCM7
minichromosome maintenance complex component 7
total:6
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Mcm7 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
MCM8
minichromosome maintenance 8 homologous recombination repair factor
ORC1
origin recognition complex subunit 1
total:1
p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation. 2005 to the paper
Abcam ORC1 antibody was used in western blot to investigate the regulation of Cdc6 protein stability by p53.
ORC2
origin recognition complex subunit 2
total:7
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Orc2 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
ORC4
origin recognition complex subunit 4
total:1
Orc1 controls centriole and centrosome copy number in human cells. 2009 to the paper
Abcam goat pAb anti-Orc4 antibody was used for western blot in order to demonstrate that the copy numbers of centriole and centrosome were regulated by Orc1 in human cells.
PA200
proteasome activator subunit 4
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal regulator PA200 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
PSMA1
proteasome 20S subunit alpha 1
total:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 to the paper
Abcam C2 proteasome antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway more
PSMA3
proteasome 20S subunit alpha 3
total:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Santa Cruz Biotechnology anti-Psc3 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
PSMA4
proteasome 20S subunit alpha 4
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International mouse monoclonal anti-human 20S proteasome subunit alpha4 was used for immunohistochemistry to investigate the effect of immunoproteasome on the Multiple Sclerosis pathogenesis. more
PSMA7
proteasome 20S subunit alpha 7
total:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Enzo Life Sciences anti-alpha7 antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
PSMB1
proteasome 20S subunit beta 1
total:2
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta1 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD). more
PSMB5
proteasome 20S subunit beta 5
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
PSMB8
proteasome 20S subunit beta 8
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP7 antibody was used for immunohistochemistry to study the effect of immunoproteasome on the Multiple Sclerosis. more
PSMB9
proteasome 20S subunit beta 9
total:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP2 antibody was used to perform immunohistochemistry to study the role of immunoproteasome in the Multiple Sclerosis pathogenesis. more
PSMC4
proteasome 26S subunit, ATPase 4
total:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 to the paper
Cell Signaling Technology anti-phospho-Ser235/236-S6 antibody was used to perform immunocytochemistry in order to study the capacity of rapamycin to provide neuroprotection in Parkinson disease models. more
PSMC6
proteasome 26S subunit, ATPase 6
total:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 to the paper
New England BioLabs antiphospho-p44/42 MAPK antibody and p44/42 MAPK antibody (PhosphoPlus p44/42 MAPK antibody kit) was used in western blot to study the physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing RhoGEFs.
PSMD2
proteasome 26S subunit, non-ATPase 2
total:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S2 subunit antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication.
PSMD4
proteasome 26S subunit, non-ATPase 4
total:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S5a antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication. more
PSMD9
proteasome 26S subunit, non-ATPase 9
total:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p27 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
PSME1
proteasome activator subunit 1
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International rabbit polyclonal anti-PA28alpha antibody was used for immunohistochemistry to determine the role of immunoproteasome in the Multiple Sclerosis. more
PSME2
proteasome activator subunit 2
total:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 to the paper
BIOMOL anti-proteasome activator 28 subunit beta (PA28beta) antibodoy was used to perform western blot in order to confirm the effect on the expression of proteasome-interacting proteins caused by chronic ethanol feeding.
RPS27A
ribosomal protein S27a
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
UBC
ubiquitin C
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
ubiquitin
ubiquitin B
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more