Assembly of collagen fibrils and other multimeric structures
gene
reagent
sample publication
sample review
BMP1
bone morphogenetic protein 1
total:1
Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation. 2005 to the paper
Affinity Bioreagents polyclonal anti-BMP-1 antibody (recognizing the CUB-2 domain) was used in western blot to study the binding of cellular fibronectin with lysyl oxidase
cathepsin B
total:14
Acid sphingomyelinase activity triggers microparticle release from glial cells. 2009 to the paper
Chemicon rabbit polyclonal anti-Cathepsin B Ab (1:200) was used in western blot in order to study the activation of acid sphingomyelinase in microparticle release from glial cells. more
cathepsin L
total:8
Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function. 2008 to the paper
Calbiochem of EMD Bioscience Inc. anti-cathepsin L antibody was used in western blot to study the effect of the role for Anaplasma phagocytophilum in increasing cathepsin L activity on neutrophil function. more
COL10A1
collagen type X alpha 1 chain
total:1
Stanniocalcin 1 acts as a paracrine regulator of growth plate chondrogenesis. 2006 to the paper
Santa Cruz Biotechnology rabbit polyclonal collagen X antibody was used in immunohistochemistry to study the effects of rhSTC on collagen X expression in control and STC-treated metatarsal bones
COL11A2
collagen type XI alpha 2 chain
total:2
Pathophysiological role of poly(ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice. 2005 to the paper
Molecular Probes anti-nitrotyrosine antibody was used in immunohistochemistry to evaluate a pathophysiological role of PARP-1. more
COL1A2
collagen type I alpha 2 chain
total:8
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 to the paper
Developmental Studies Hybridoma Bank anti-collagen-I antibody was used to perform western blot in order to investigate the mechanism of Golgi-mediated protein traffic. more
COL4A1
collagen type IV alpha 1 chain
total:9
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
Abcam anti Col IV antibody was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
COL4A3
collagen type IV alpha 3 chain
total:5
Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. 2005 to the paper
Santa Cruz Biotechnology goat anti-alpha3 antibody was used in western blot to study the effect of activation of vascular endothelial growth factor receptor 3 on endothelial function and infection. more
COL4A4
collagen type IV alpha 4 chain
total:2
ELR-negative CXC chemokine CXCL11 (IP-9/I-TAC) facilitates dermal and epidermal maturation during wound repair. 2008 to the paper
Abcam rabbit polyclonal collagen IV antibody was used in immunohistochemistry in order to study the role of IP-10 and IP-9 in epidermal maturation during wound repair more
COL4A6
collagen type IV alpha 6 chain
total:4
Comparison between human fetal and adult skin. 2010 to the paper
Dako anti-Collagen type IV was used to perform immunohistochemistry in dilution 1:250 in order to show that dermal components express differentially between human fetal and adult skin and play important roles in fetal scarless healing. more
COL6A1
collagen type VI alpha 1 chain
total:2
The extracellular matrix glycoprotein elastin microfibril interface located protein 2: a dual role in the tumor microenvironment. 2010 to the paper
Santa Cruz Biotechnology anti-type I collagen antibody was used in western blot in order to investigate the function of the 90-amino acid residue fragment of elastin microfibril interface located protein 2 (EMILIN2) in the tumor microenvironment. more
CTSS
cathepsin S
total:4
T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. 2009 to the paper
Abcam goat polyclonal anti-cathepsin S was used to block and incubate the blots in order to suggest that T-cell activation can limits collagen maturation in the atherosclerotic plaque. more
CTSV
cathepsin V
total:2
Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification. 2006 to the paper
R&D Systems monoclonal mouse-anti-human CTSV antibody was used in immunohistochemistry to study cystatin M/E as a high affinity inhibitor of cathepsin V and cathepsin L through a reactive site that is distinct from the legumain-binding site more
endostatin
collagen type XVIII alpha 1 chain
total:4
Reduction of endogenous angiogenesis inhibitors in Bruch's membrane of the submacular region in eyes with age-related macular degeneration. 2008 to the paper
R&D Systems anti-endostatin antibody was used to perform immunohistochemistry in order to study the level of angiogenesis inhibitors in eyes with age-related macular degeneration. more
ITGA6
integrin subunit alpha 6
total:20
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD49f-PE antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
ITGB4
integrin subunit beta 4
total:12
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-ITGB4 antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
LAMA3
laminin subunit alpha 3
total:3
Nephrotic syndrome and aberrant expression of laminin isoforms in glomerular basement membranes for an infant with Herlitz junctional epidermolysis bullosa. 2005 to the paper
Chemicon monoclonal anti-laminin alpha3 chain antibody P3H9 was used in immunohistochemistry to study the association of laminin isoforms with herlitz junctional epidermolysis bullosa in a case complicated by nephrotic syndrome. more
LAMC2
laminin subunit gamma 2
total:6
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
Millipore anti-laminin gamma 2 chain antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
lysyl oxidase
total:2
T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. 2009 to the paper
Novus Biologicals rabbit polyclonal anti-LOX was used to block and incubate the blots in order to suggest that T-cell activation can limits collagen maturation in the atherosclerotic plaque. more
MMP-3
matrix metallopeptidase 3
total:8
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-3 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
MMP-7
matrix metallopeptidase 7
total:9
Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma. 2010 to the paper
Santa Cruz Biotechnology anti-MMP7 antibody was used in immunohistochemistry to investigate the function of UPK1A in esophageal squamous cell carcinoma. more
MMP-9
matrix metallopeptidase 9
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
MMP13
matrix metallopeptidase 13
total:7
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-13 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
PLEC
plectin
total:5
Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength. 2009 to the paper
Epitomics rabbit monoclonal anti-plectin antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the function for beta3 integrin-mediated vimentin IF recruitment to the cell surface. more
TLL2
tolloid like 2
total:2
Expression of Toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis. 2008 to the paper
Santa Cruz Biotechnology rabbit TLR2 polyclonal antibody(1:10) was used to perform immunohistochemistry in order to investigate the expression of TLR2, TLR4, and their transmembrane coreceptor CD14 in the intestinal mucosa of terminal ileum. more
type I collagen
collagen type I alpha 1 chain
total:21
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. 2010 to the paper
Abcam anti-collagen I antibody was used to perform immunohistochemistry and immunocytochemistry in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors. more
type II collagen
collagen type II alpha 1 chain
total:15
A stem cell-based approach to cartilage repair. 2012 to the paper
Abcam anti-type II collagen antibody was used to perform immunocytochemistry in order to show that kartogenin could be used to induce chondrocyte differentiation for osteoarthritis treatment. more
type III collagen
collagen type III alpha 1 chain
total:13
TNF-alpha regulates the effects of irradiation in the mouse bone marrow microenvironment. 2010 to the paper
Chemicon anti-collagen IV antibody was used to carry out dot-blotting analysis in order to investigate the role of TNF-a in irradiation-induced bone marrow cell apoptosis and bone marrow dysfunction. more