Arachidonic acid metabolism
gene
reagent
sample publication
sample review
ALOX12
arachidonate 12-lipoxygenase, 12S type
total:2
Role of 12-lipoxygenase in volatile anesthetic-induced delayed preconditioning in mice. 2006 to the paper
Cayman Chemical 12-LO primary antibody was used in western blot to study the role of 12-lipoxygenase in volatile anesthetic-induced delayed preconditioning in mice. more
ALOX5
arachidonate 5-lipoxygenase
total:6
A mutant of hepatitis B virus X protein (HBxDelta127) promotes cell growth through a positive feedback loop involving 5-lipoxygenase and fatty acid synthase. 2010 to the paper
Santa Cruz Biotechnology anti-5-LOX antibody was used to perform western blotting in order to study how the cell growth are promoted by research on a mutant of HBx. more
CBR1
carbonyl reductase 1
total:2
Differential expression of prostaglandin (PG) synthesis enzymes in conceptus during peri-implantation period and endometrial expression of carbonyl reductase/PG 9-ketoreductase in the pig. 2007 to the paper
Abcam 1:2000 polyclonal anti-human CBR1 antibody was used in western blot to study the role of prostaglandins (PGs) in luteolysis, maternal recognition of pregnancy, and implantation. more
Cyp1A1
cytochrome P450 family 1 subfamily A member 1
total:15
Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. 2009 to the paper
Chemicon International anti-CYP 1A1 antibody (AB1258) was used in western blot to determine the functional significance of aryl hydrocarbon receptor (AhR) in gastric carcinogenesis, and to explore the possible role of AhR in gastric cancer (GC) treatment more
CYP1A2
cytochrome P450 family 1 subfamily A member 2
total:2
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Alexis Biochemicals mouse anti-Mrp2 antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes. more
CYP1B1
cytochrome P450 family 1 subfamily B member 1
total:8
Preferential induction of cytochrome P450 1A1 over cytochrome P450 1B1 in human breast epithelial cells following exposure to quercetin. 2008 to the paper
Santa Cruz affinity purified goat polyclonal Cyp1B1 antibody was used in western blot in order to study the role of estrogen metabolism in estrogen-induced breast carcinogenesis more
CYP2C8
cytochrome P450 family 2 subfamily C member 8
total:3
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 to the paper
BD Biosciences-Pharmingen monoclonal anti-cytochrome c antibody was used in immunohistochemistry in order to introduce a rapid regulation of mitochondrial dynamics in acute kidney injury. more
CYP2C9
cytochrome P450 family 2 subfamily C member 9
total:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
BD Gentest anti-CYP2C9 antibody (1:1000) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
CYP4A22
cytochrome P450 family 4 subfamily A member 22
CYP4F11
cytochrome P450 family 4 subfamily F member 11
total:1
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 to the paper
Proteintech polyclonal anti-CYP4F11 antibody was used to perform western blot in order to clarify that retinoic acid could inhibit CYP4F11 expression in human keratinocyte-derived HaCaT cells by multiple signaling pathways including RXR and JNK pathways.
CYP4F2
cytochrome P450 family 4 subfamily F member 2
CYP4F22
cytochrome P450 family 4 subfamily F member 22
CYP4F8
cytochrome P450 family 4 subfamily F member 8
CYP8B1
cytochrome P450 family 8 subfamily B member 1
GPX1
glutathione peroxidase 1
total:3
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
Affinity BioReagents ATP synthase antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction. more
MK2
MAPK activated protein kinase 2
total:18
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Cell Signaling Technology anti-MAPKAPK 2 (pT334) was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
PGIS
prostaglandin I2 synthase
total:4
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. 2005 to the paper
Oxford Biomedical Research mouse monoclonal PGIS antibody was used in western blot to demonstrate that the mPGES-1 enzyme is a primary release mechanism of PGH2 accumulation. more
PLA2G4A
phospholipase A2 group IVA
total:8
Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.. 2009 to the paper
Santa Cruz Biotechnology anit-cPLA2a antibody was used to perform western blot and immunocytochemistry to study the role of cPLA2a in the formation of intercisternal tubular continuities and transport through the Golgi complex. more
prostaglandin E synthase
total:9
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-mPGES-1 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
PTGDS
prostaglandin D2 synthase
total:2
Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid. 2007 to the paper
Osaka Bioscience Institute rabbit polyclonal anti-human L-PGDS (1:1,000 dilution) and anti-mouse L-PGDS (1:4,000 dilution) antibodies were used in immunohistochemistry to demonstrate lipocalin-type prostaglandin D synthase/beta-trace as a major amyloid beta-chaperone in human cerebrospinal fluid. more
PTGES3
prostaglandin E synthase 3
total:5
High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance. 2010 to the paper
Thermo Fisher anti-p23 antibody was used for performing immunoblotting and immunohistochemistry in order to study the effect of high levels of Hsp90 cochaperone p23 on tumor progression and prognosis in breast cancer. more
PTGS1
prostaglandin-endoperoxide synthase 1
total:12
Cyclooxygenase-2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha. 2009 to the paper
Santa Cruz anti-COX-1 antibody was used to perform western blot and immunohistochemistry in order to show that the cyclooxygenase-2 can leads to the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma. more
PTGS2
prostaglandin-endoperoxide synthase 2
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
TBXAS1
thromboxane A synthase 1
total:3
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 to the paper
Abcam anti-TBXAS1 antibody was used to perform western blot in order to study the novel BRAF fusion gene in 7q34 duplication of pediatric low-grade astrocytomas detected by high density SNP-based genotype array analysis. more