Apoptosis
gene
reagent
sample publication
sample review
total:9
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3beta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
total:5
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Santa Cruz Biotechnology anti-14-3-3epsilon antibody (1:2000) was used in western blot to study the effects of curcumin on the expression of peroxisome proliferator-activated receptor delta (PPARdelta) and related genes in HT-29 cells. more
total:3
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3gamma antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
total:21
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Santa Cruz Biotechnology anti-14-3-3 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
total:6
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3zeta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
total:13
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. 2008 to the paper
Santa Cruz Biotechnology anti-TACE antibody was used to perform Western Blot in order to show that TACE has a inhibitory role in EGFR axis in colorectal cancer. more
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:4
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. 2008 to the paper
Millipore anti-Akt3 was used to perform western blot in order to show that PTEN-null tumors is promoted to autophagy and more sensitive to lysosomotropic agents after Akt inhibition. more
total:9
Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization. 2010 to the paper
Bioquote monoclonal anti-Apaf-1 antibody was used for western blot in order to investigate the role of XIAP in the regulation of mitochondrial permeabilization. more
total:11
A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis. 2009 to the paper
Calbiochem anti-APC was used to perform immunocytochemistry in order to show that MRP protein plays an important role in adherens junction formation and tumorigenesis more
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Cell Signaling Technology, anti-BAD monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:27
Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. 2010 to the paper
Upstate Biotech anti-Bak NT antibody was used to perform immunoprecipitation and western blot in order to study the interactions between Bak and F1L or Mcl1. more
total:102
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 to the paper
Santa Cruz anti-BAX was used to perform western blot in order to show that chemotherapy is efficient for patients with high mitochondrial priming more
total:130
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Santa Cruz anti-Bcl-2 antibody (C-2, sc-7382, 1:500) was used to perform western blot in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
total:85
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. 2008 to the paper
Santa Cruz Biotechnology mouse anti-Bcl-XL monoclonal antibody was used to perform western blot in order to study the function of the natural product honokiol. more
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
total:35
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 to the paper
Santa Cruz anti-Bid was used to perform western blot in order to show that chemotherapy is efficient for patients with high mitochondrial priming more
total:31
Control of cellular Bcl-xL levels by deamidation-regulated degradation. 2013 to the paper
Calbiochem anti-Bim antibody was used to perform immunoprecipitation in order to investigate the regulatory effect of deamidation on Bcl-xL degradation. more
total:1
Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection. 2009 to the paper
Cell Signaling Bmf antibody was used in western blot in order to study the effect of Bim and Bmf on Neisseria Gonorrhoeae infected cells.
total:15
Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination. 2011 to the paper
Alexis anti-cIAP1 was used to perform western blot in order to show that autoubiquitination could be promoted by conformational change of cIAP1 induced by antagonists. more
total:9
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. 2006 to the paper
R & D Systems anti-caspase-10 antibody was used in human THP-1 cells and in western blot to study the roles for the interaction of the B30.2 domain of pyrin, the familial mediterranean fever protein with caspase-1 in IL-1 production. more
total:212
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Abcam Caspase-3 antibody was used to perform immunohistochemistry in order to study theeffect of thiabendazole on proliferation and apoptosis of human cells. more
total:12
Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6. 2010 to the paper
Abcam monoclonal anti-caspase-6 antibody was used for western blot in order to investigate the role of DJ-1 mutations in the regulation of Parkinson disease pathology. more
total:23
Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI. 2008 to the paper
Santa Cruz Caspase-7 antibody was used in western blot in order to analyze changes in a subproteome of ~800 proteins in the promyelocytic leukemia cell line HL-60 upon treatment with the proteasome inhibitor PSI more
total:73
Detachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis. 2009 to the paper
R&D systems anti-casp8 antibody was used to carry out western blot analysis in order to investigate the mechanism of DR5 relocalization and its effect on cell apoptosis during adhesion to detachment of EC9706 cells. more
total:75
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-caspase-9 antibody was used to perform immunocytochemistry in order to study the protective autophagy involved in trail resistance of apoptosis-defective tumor cells. more
total:6
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Bethyl Laboratories rabbit anti-Claspin antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
total:48
Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. 2010 to the paper
BD PharMingen anti-cytochrome c antibody was used to perform western blot in order to study the interaction between F1L and endogenous Bak. more
total:2
Netrin-1 inhibits leukocyte migration in vitro and in vivo. 2005 to the paper
Santa Cruz Biotechnology goat anti-mouse DCC antibody was used in immunocytochemistry to study the effect of netrin-1 on leukocyte migration more
total:11
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 to the paper
Serotec anti-desmoplakin was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis. more
total:8
Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis. 2007 to the paper
Chemicon International ICAD antibody was used in western blot to study the role of semaphorin 7A in TGF-beta1-induced pulmonary fibrosis more
total:3
Oligomerization state of the DNA fragmentation factor in normal and apoptotic cells. 2005 to the paper
BD Pharmingen rabbit polyclonal anti-human CAD antibody was used in western blot to study the oligonucleosomal DNA fragmentation factor in normal and apoptotic cells. more
total:4
ER tubules mark sites of mitochondrial division. 2011 to the paper
Abcam anti-Dnm1L was used to perform western blot in order to show that mitochondrial fission could be mediated by ER tubules. more
total:15
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 2010 to the paper
eBioscience rabbit polyclonal anti-DR5 antibody was used in flow cytometry in order to investigate the roles of Fas ligand and TRAIL in the regulation of murine thymic graft-versus-host disease. more
total:5
The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes. 2006 to the paper
Research Diagnostics monoclonal anti-Dsg1 antibody (clone P124, which recognizes N-terminal extracellular domain of Dsg1) was used in parental A431 human vulvar epidermoid carcinoma cells and in western blot to study the function for Dsg1 in facilitating apoptotic elimination of damaged cells. more
total:3
Limbal epithelial crypt: a model for corneal epithelial maintenance and novel limbal regional variations. 2008 to the paper
Zymed Laboratories anti-desmoglein 3 antibody was used to perform immunohistochemistry in order to study the distribution of cell membrane proteins and extracellular matrix proteins in human corneoscleral limbus rims. more
total:3
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix. 2009 to the paper
Abcam monoclonal anti-dynein antibody (74.1ab23905) was used in blocking or activating expriments to study the roles for nudel and dynein in assembly of the lamin B spindle matrix. more
total:129
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Invitrogen rat anti-E-Cadherin (ECCD-2; 13-1900) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
total:37
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Santa Cruz E2F1 antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:19
Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis. 2008 to the paper
Cell Signaling Technology anti-FADD antibody was used to perform western blot in order to assess the effect of Rk1 on cell viability and telomerase activity. more
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:52
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Santa Cruz Biotechnology FAS antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
total:12
HYAL1-v1, an alternatively spliced variant of HYAL1 hyaluronidase: a negative regulator of bladder cancer. 2006 to the paper
Santa Cruz Biotechnology anti-Fas-L antibody was used in western blot to study the role of HYAL1-v1 in regulating in bladder cancer growth, infiltration, and angiogenesis in transfected human HT1376 bladder cancer cells. more
total:16
CK2beta is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation. 2009 to the paper
Santa Cruz anti-FLIP antibody was used to perform immunohistochemistry in order to show the role of CK2B in apoptosis resistance and cell proliferation in endometrial carcinoma. more
total:1
The calpain system is involved in the constitutive regulation of beta-catenin signaling functions. 2005 to the paper
Sigma anti-Gas2 antibody was used in western blot to study constitutive regulation of beta-catenin signaling functions
total:8
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Sigma anti-gelsolin antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
total:4
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. 2009 to the paper
Santa Cruz Biotechnology mouse anti-granzyme B monoclonal antibody was used to carry out immunofluorescence assays in order to investigate the mechanism for IL-33 in promoting allergic inflammation. more
total:3
DNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositides. 2009 to the paper
Santa Cruz anti-histone H1 antibody was used for western blot in order to illustrate the new functions of SAP30L and SAP30 in mediating key protein-protein and protein-DNA interactions involved in chromatin remodeling and transcription. more
total:3
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Abcam anti-histone H1 antibody was used to perform western blot in order to study the DNA damage and response by UV. more
total:1
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. 2009 to the paper
Abcam anti-histone H1.4K26me2 was used to perform western blot in order to show the effects of G9a/KMT1C and jumonji-C type histone demethylases in histone H1 isotype 4 methylation and demethylation.
total:2
The cell cycle timing of centromeric chromatin assembly in Drosophila meiosis is distinct from mitosis yet requires CAL1 and CENP-C. 2012 to the paper
Chemicon mouse anti-pan-histone antibody was used to perform immunostaining in order to study the cell cycle timing of CID assembly in mitosis and meiosis. more
total:7
ATM, the Mre11/Rad50/Nbs1 complex, and topoisomerase I are concentrated in the nucleus of Purkinje neurons in the juvenile human brain. 2007 to the paper
Santa Cruz mouse anti-Histone H1 monoclonal antibody(1:100) was used to perform immunofluoresence in order to study the mechanism of genetic disease ataxia telangiectasia (AT) in the nucleus of human Purkinje neurons. more
total:10
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Abcam anti-HMGB1 antibody was used to perform western blot in order to study the role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:2
HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalpha. 2009 to the paper
Aviva anti-HMGB2 antibody was used to detect HMGB2 in SDS-PAGE in order to prove that HMGB1 and HMGB2 proteins can enhance the expression of human topoisomerase II alpha. more
total:193
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-JNK1 monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:1
Novel nuclear import of Vpr promoted by importin alpha is crucial for human immunodeficiency virus type 1 replication in macrophages. 2007 to the paper
MBL monoclonal importin alpha 5/7 antibody was used in western blot to study novel nuclear import of Vpr promoted and its roles in human immunodeficiency virus type 1 replication in macrophages
total:7
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-importin beta antibody (sc-137016) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
total:57
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Santa Cruz lamin A/C goat polyclonal (1:1000)was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more
total:31
CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin. 2010 to the paper
Santa Cruz anti-lamin-B antibody was used for western blot in order to show that CYLD negatively regulates cell-cycle progression by inactivating HDAC6. more
total:1
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 to the paper
Santa Cruz goat anti-NRAGE antibody was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity.
total:1
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 to the paper
BD Transduction Laboratories anti-NMT1 antibody was used in western blot to detect NMT1 in SK-OV-3 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.
total:4
A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis. 2007 to the paper
Oncogene Research Products NOXA antibody was used in western blot to identify p18 (Hamlet) as a new cell-fate regulator. more
total:21
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
Santa Cruz anti-occludin antibody was used to perform immunocytochemistry in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal regulator PA200 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
total:6
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 to the paper
Santa Cruz Biotechnology anti-PAK-2 antibody was used for western blot in order to investigate the role of PAK-2 in the regulation of anticancer drug-induced cell apoptosis. more
total:35
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. 2009 to the paper
Santa Cruz Biotechnology anti-PKCdelta antibody was used in western blot to study the mechanism underlying PKCalpha suppressing tumor in the intestine. more
total:5
Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength. 2009 to the paper
Epitomics rabbit monoclonal anti-plectin antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the function for beta3 integrin-mediated vimentin IF recruitment to the cell surface. more
total:3
Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. 2006 to the paper
Sigma CnB1 antibody was used in western blot to demonstrate direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. more
total:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKCtheta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
total:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 to the paper
Abcam C2 proteasome antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway more
total:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Santa Cruz Biotechnology anti-Psc3 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International mouse monoclonal anti-human 20S proteasome subunit alpha4 was used for immunohistochemistry to investigate the effect of immunoproteasome on the Multiple Sclerosis pathogenesis. more
total:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Enzo Life Sciences anti-alpha7 antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:2
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta1 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD). more
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP7 antibody was used for immunohistochemistry to study the effect of immunoproteasome on the Multiple Sclerosis. more
total:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP2 antibody was used to perform immunohistochemistry to study the role of immunoproteasome in the Multiple Sclerosis pathogenesis. more
total:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 to the paper
Cell Signaling Technology anti-phospho-Ser235/236-S6 antibody was used to perform immunocytochemistry in order to study the capacity of rapamycin to provide neuroprotection in Parkinson disease models. more
total:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 to the paper
New England BioLabs antiphospho-p44/42 MAPK antibody and p44/42 MAPK antibody (PhosphoPlus p44/42 MAPK antibody kit) was used in western blot to study the physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing RhoGEFs.
total:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S2 subunit antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication.
total:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S5a antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication. more
total:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p27 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International rabbit polyclonal anti-PA28alpha antibody was used for immunohistochemistry to determine the role of immunoproteasome in the Multiple Sclerosis. more
total:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 to the paper
BIOMOL anti-proteasome activator 28 subunit beta (PA28beta) antibodoy was used to perform western blot in order to confirm the effect on the expression of proteasome-interacting proteins caused by chronic ethanol feeding.
total:12
Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer. 2008 to the paper
Calbiochem anti-PUMA antibody was used in western blot to study the mechanism and effect of p53 activation by a potent and specific MDM2 antagonist (MI-43) in colon cancer. more
total:9
Repression of NF-kappaB and activation of AP-1 enhance apoptosis in prostate cancer cells. 2009 to the paper
Santa Cruz Biotechnology anti-RIP antibody was used in western blot to study the effect of repression of NF-kB and activation of AP-1 on apoptosis in prostate cancer cells. more
total:8
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 to the paper
Santa Curz anit-ROCK1 antibody was used to perform western blot to study the different roles of ROCK1 and ROCK2 in regulating keratinocyte adhesion and terminal differentiation. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:2
Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1. 2009 to the paper
Santa Cruz Biotechnology acetylated SATB1 antibody was used in western blot in order to study the role of SATB1-CtBP1 interaction in the repression and derepression of SATB1 target genes during Wnt signaling in T cells more
total:16
Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization. 2010 to the paper
Calbiochem anti-Smac/DIABLO antibody (1/3000) was used to perform ELISA in order to study the function of cancer cell lines mitochondria in exploring the mechanisms of mitochondrial membrane permeabilization induced by BH3 peptides and ABT-737. more
total:6
Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ labeling, multidimensional liquid chromatography, and tandem mass spectrometry. 2008 to the paper
Santa Cruz Biotechnology anti-stratifin antibody was used in immunohistochemistry and western blot to discover head-and-neck cancer biomarkers. more
total:45
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Proteintech Group MAPT antibody (1:1500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
total:1
Identification and characterization of novel isoforms of human DP-1: DP-1{alpha} regulates the transcriptional activity of E2F1 as well as cell cycle progression in a dominant-negative manner. 2005 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-DP-1 antibody was used in western blot to identify and Characterize the novel isoforms of human DP-1.
total:3
EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability. 2008 to the paper
Zymed Laboratories rabbit polyclonal anti-ZO-2 antibody was used in western blot and immunocytochemistry to study the role for EspF in pedestal maturation and the disruption of paracellular permeability. more
total:68
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-TNFa-PE or -APC antibody was used to perform flow cytometry in order to study the diffrent trafficking mechanisms of endosomal TLRs mediated by UNC93B1. more
total:23
Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation. 2009 to the paper
Santa Cruz anti-TNFR1 antibody was used to perform western blot in order to study the mechanism that TRAF2 inhibits stress-induced cell death. more
total:26
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TRAF2 (C-20) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:6
Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells. 2005 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-TRAIL antibody was used in western blot to investigate the role of human BVR in sodium arsenite (As) mediated induction of HO-1 and in cytoprotection against apoptosis by small interference RNA-mediated gene silencing. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:1
Unc5B associates with LARG to mediate the action of repulsive guidance molecule. 2009 to the paper
R&D Systems Unc5B antibody was used for western blot in order to investigate the role of Unc5B and LARG in the regulation of repulsive guidance molecule.
total:76
Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-vimentin (C-20 and H-84, 1:1000) antibody was used to perform western blot in order to study the formation mechanism of tubulin-based microtentacles in detached breast tumor cells. more
total:28
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance. 2009 to the paper
R&D systems anti-XIAP antibody was used in western blot to investigate the role of PARP-1 in the NF-kB signalling cascade induced by ionizing radiation more
total:55
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Zymed mouse anti-ZO-1 (1:1,000) antibody was used to perform immunofluorescence in order to study the role for TRAF4, a novel phosphoinositide-binding protein, in modulating tight junctions and promoting cell migration. more