Activation of NMDA receptor upon glutamate binding and postsynaptic events
gene
reagent
sample publication
sample review
ACTN2
actinin alpha 2
total:3
UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) binds to alpha-actinin 1: novel pathways in skeletal muscle?. 2008 to the paper
Sigma monoclonal anti-alpha-actinin-2 antibody was used in immunohistochemistry to study the role for the binding of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) with alpha-actinin 1 in skeletal muscle. more
ADCY1
adenylate cyclase 1
total:2
Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. 2005 to the paper
FabGennix isoform-specific anti-adenylate cyclase antibody was used in western blot to study the effedt of interferon-gamma on adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia. more
ADCY3
adenylate cyclase 3
total:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Santa Cruz anti-adenylyl cyclase III antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
B-Raf
B-Raf proto-oncogene, serine/threonine kinase
total:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
CAMK2A
calcium/calmodulin dependent protein kinase II alpha
total:13
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 to the paper
Affinity Bioreagents anti-phospho-CaMKII antibody was used for western blot in order to investigate the role of CaMKII in the regulation of pressure overload-induced cardiac hypertrophy to heart failure in mice. more
CAMK2G
calcium/calmodulin dependent protein kinase II gamma
total:10
Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2. 2010 to the paper
Santa Cruz anti-phos-CaMKII antibody was used to perform western blot in order to study the role of cGMP-dependent protein kinase and RGS2 in local antihypertrophic effects of cardiac atrial natriuretic peptide. more
CAMK4
calcium/calmodulin dependent protein kinase IV
total:3
Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation. 2005 to the paper
Transduction Laboratories monoclonal anti-CaMKIV antibody was used in western blot and immunocytochemistry to study the presence of CaMKIV in mammalian sperm and its role in the regulation of human sperm motility. more
CREB
cAMP responsive element binding protein 1
total:58
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
ERK2
mitogen-activated protein kinase 1
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
GluR1
glutamate ionotropic receptor AMPA type subunit 1
total:12
Parallel memory processing by the CA1 region of the dorsal hippocampus and the basolateral amygdala. 2008 to the paper
Santa Cruz Biotechnology anti-pGluR1 antibdoy was used in western blot in order to investigate molecular correlates of IA consolidation in the hippocampus and the basolateral amygdala structures and their relation to NMDA receptors (NMDArs) and beta-adrenergic receptors (beta-ADrs) more
GluR2
glutamate ionotropic receptor AMPA type subunit 2
total:9
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. 2009 to the paper
Chemicon rabbit anti-GluR2 antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity. more
GRF2
Ras protein specific guanine nucleotide releasing factor 2
GRIA3
glutamate ionotropic receptor AMPA type subunit 3
total:3
Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. 2006 to the paper
Millipore GluR3 antibody was used in western blot and immunoprecipitation to study the function of alsin gene. more
GRIA4
glutamate ionotropic receptor AMPA type subunit 4
total:2
TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. 2005 to the paper
Upstate Biotechnology GluR4 antibody was used in western blot to study cell-autonomous role of TrkB in the establishment of hippocampal Schaffer collateral synapses. more
GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
total:9
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. 2009 to the paper
Chemicon rabbit anti-NR2A antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity. more
H-Ras
HRas proto-oncogene, GTPase
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
neurofilament L
neurofilament light
total:20
The geometric structure of the brain fiber pathways. 2012 to the paper
Abcam mouse monoclonal anti-Neurofilament was used at 1:1000 to perform immunohistochemistry in order to show the architecture of the brain fiber pathways. more
NR1
glutamate ionotropic receptor NMDA type subunit 1
total:21
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. 2009 to the paper
Chemicon rabbit anti-NR1 antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity. more
NR2B
glutamate ionotropic receptor NMDA type subunit 2B
total:10
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. 2009 to the paper
Chemicon rabbit anti-NR2B antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity. more
p90rsk
ribosomal protein S6 kinase A1
total:20
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Santa Cruz anti-RSK-1 antibody (1:1,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediates anti-apoptotic effects. more
PRKACA
protein kinase cAMP-activated catalytic subunit alpha
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
PRKACG
protein kinase cAMP-activated catalytic subunit gamma
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
PSD-95
discs large MAGUK scaffold protein 4
total:24
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
Thermo Scientific monoclonal anti-PSD-95 antibody was used to carry out western blot analysis and immunofluorescence assays in order to determine the atomic structure of human adenovirus. more
Raf-1
Raf-1 proto-oncogene, serine/threonine kinase
total:46
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. 2010 to the paper
Santa Cruz Biotechnology anti-RAF1 antibody was used to perform western blot in order to study the role of microRNA-7 in tongue squamous cell carcinoma cells. more
RPS6KA2
ribosomal protein S6 kinase A2
total:9
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 to the paper
Cell Signaling anti-phosphorylated p90RSK antibody was used to perform western blot in order to study the important role of GRK4 in D3 receptor's signaling in human proximal tubule cells. more
RPS6KA3
ribosomal protein S6 kinase A3
total:9
Mitogen-activated protein kinase-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection. 2009 to the paper
Santa Cruz anti-RSK2 antibody was used to perform western blot in order to study the role of RSK2 in the cellular antiviral response. more