Overview
Labome lists 449244 antibody products against 41374 genes, including 15695 human, 11355 mouse, and 9387 rat genes.

Labome antibody review database lists 36118 antibody applications for 7982 genes, based on 8163 formal publications. see examples: p53 antibody, beta actin antibody, GFP, integrin antibody, tubulin antibody, insulin antibody, and Myc antibody.

Gene Overview
Labome antibody review database contains antibody applications for 2021 genes with antibodies supplied from Sigma based on 864 formal publications.
Select Gene Review
  • beta-actin gene: 57 publications, see all beta-actin antibody application review
    • Sigma rabbit anti-actin antibody was used in western blot as control to study TOGp (human homolog of XMAP215/Dis1) is required for centrosome integrity, spindle pole organization and bipolar spindle assembly.
    • Sigma anti-beta-actin was used as a probe in western blot in order to prove that the loss of full length CtBP1 expression can induce human melanoma
    • Sigma anti-?-actin antibody was used in immunoprecipitation in order to confirm that histone ubiquitination cause DNA damage.
    • Sigma anti-??-Actin antibody was used in western blot to indentify CK2 as a PER2-phosphorylating kinase and novel component of the mammalian circadian clock.
    • Sigma anti-beta-actin antibody was used in western blot to study the heterogeneous nuclear ribonucleoprotein A1 as a novel internal ribosome entry site trans-acting factor which modulates alternative initiation of translation of the fibroblast growth factor 2 mRNA.
  • vinculin gene: 30 publications, see all vinculin antibody application review
    • Sigma mouse monoclonal anti-human vinculin antibody was used in western blot and ChIP assay in order to demonstrate that annexin A1 promoter activity is controlled by a functional cooperation between p53 and factors binding to the proximal CCAAT box
    • Sigma monoclonal anti-vinculin antibody was used in immunohistochemistry to study the role of punctinin the extracellular matrix.
    • Sigma monoclonal anti-vinculin antibody was used in immunocytochemistry to study its induction of F-actin reorganization
    • Sigma mouse anti-vinculin was used in immunocytochemistry to visualize focal adhesions in bovine aortic endothelial (BAE) cells
    • Sigma monoclonal vinculin antibody was used in western blot and immunoprecipitation to study the association of gelsolin with SH2-containing signaling proteins
  • gamma-tubulin gene: 23 publications, see all gamma-tubulin antibody application review
    • Sigma mouse anti-gamma-tubulin monoclonal antibody was used in immunocytochemistry to detect gamma-tubulin in 293 and U2OS cells.
    • Sigma gamma-tubulin monoclonal and polyclonal antibodies were used in immunocytochemistry to study the interaction between EB1 and p150Glued
    • Sigma Cy3-conjugate anti-gamma-tubulin antibody was used in immunocytochemistry to stain for gamma-tubulin in HEK293 cells
    • Sigma mouse anti-gamma-tubulin monoclonal antibody was used in immunocytochemistry to study the parkin accumulation in aggresomes due to proteasome impairment.
    • Sigma anti-gamma-tubulin antibody was used in western blot to study the regulation of human Rif1, ortholog of a yeast telomeric protein by ATM and 53BP1 and functions in the S-phase checkpoint.
  • actin gene: 23 publications, see all actin antibody application review
    • Sigma Anti-actin was used to do immunoprecipitation in order to study the role of MERIT40 in BRCA1 localization and DNA damage repair
    • Sigma mouse anti-Actin antibody was used in immunoblots to detect cell lysate in order to conform that autophagy can sensitize apoptosis during deprivation of growth factors.
    • Sigma monoclonal anti alpha-sarcomeric actin antibody was used in immunocytochemistry to study cardiotrophin-1 effect on cardiac fibroblast growth
    • Sigma anti-actin antibody was used to perform western blot in order to study the role estradiol plays in activating the beta-Catenin dependent transcription in neurons.
    • Sigma ??-actin was used for western blot in order to dentify miR-181a as a regulator of p27 mRNA translation during myeloid cell differentiation.
  • alpha-tubulin gene: 22 publications, see all alpha-tubulin antibody application review
    • Sigma mouse monoclonal alpha-tubulin antibody was used for western blot in order to investigate the role of SRPK1 in the regulation of SR protein phosphorylation.
    • Sigma mouse monoclonal anti-tubulin antibody was used in human HeLa cells and in immunocytochemistry to study the role for PKC in controlling traffic pathway for c-Met that operates independently of its degradative pathway.
    • Sigma monoclonal mouse anti human tubulin antibody was used in western blot as a control to study the apoptosis in p53-defective tumors
    • Sigma anti-tubulin monoclonal antibody (clone DM1A) was used in western blot as a loading control to study the expression of splice variants of DCLK in embryonic and adult brain.
    • Sigma anti-{alpha}-tubulin antibody was used in western blot to study tumor suppression by the von Hippel-Lindau protein
  • beta-actin gene: 19 publications, see all beta-actin antibody application review
    • Sigma anti-b-actin antibody was used as loading control to carry out western blot analysis in order to identify transcription factors potentially important for mammalian neuronal differentiation by a high throughput ES cell screen.
    • Sigma FITC-conjugated anti-beta-actin antibody was used in immunocytochemistry to detect beta-actin in mouse C2C12 cells grown on coverslips transiently transfected with a construct encoding wild type Ndrg2.
    • Sigma goat anti-?-actin antibody was used for the Western blot in order to show that neutrophils traverse human dermal microvascular endothelial cells using one of two pathways: a transcellular route directly through the cell or a paracellular route through cellular junctions.
    • Sigma anti-beta-actin antibody was used to perform western blot in order to show that PLC?2 is an important player in integrin and Fc receptor-mediated neutrophil functions and the neutrophil-mediated effector phase of autoimmune arthritis.
    • Sigma anti-beta Actin antibody was used to perform western blot in order to study the role of E2f3b in in myogenic differentiation.
  • alpha-tubulin gene: 17 publications, see all alpha-tubulin antibody application review
    • Sigma mouse monoclonal anti-alpha-Tubulin antibody was used for western blot in order to investigate the role of Neuroglian in the regulation of Lis1 localization in circulating immunosurveillance cells..
    • Sigma monoclonal anti-alpha-tubulin antibody was used in western blot to detect alpha-tubulin as loading control in COS cells expressing MuSK protein.
    • Sigma anti-alpha-tubulin antibody was used for western blot in order to investigate the roles of MDA5 and PTPN2 in the regulation of pancreatic ??-cell responses to the viral by-product double-stranded RNA.
    • Sigma anti-alpha-tubulin antibody was used in western blot to detect alpha-tubulin as a loading control in human umbilical vascular endothelial cell (HUVEC) expressing Nek2 and C-Nap1.
    • Sigma anti-tyrosinated alpha-tubulin antibody was used for western blot in order to show that CYLD negatively regulates cell-cycle progression by inactivating HDAC6.
  • Tubulin gene: 16 publications, see all Tubulin antibody application review
    • Sigma anti-Tubulin antibody was used in western blot in order to demonstrate that Shp2 tyrosine phosphatase can regulate human and mouse embryonic stem cell pluripotency and differentiation.
    • Sigma mouse monoclonal anti-alpha-tubulin antibody (clone B-5-1-2) was used in tissue from mouse and in western blot to study the effect of targeted deletion of the muscular dystrophy gene myotilin on muscle structure or function in mice.
    • Sigma anti-?-tubulin was used to perform immunohistochemistry in order to study the therapeutic approaches of pompe disease in murine muscle cell models.
    • Sigma anti-alpha-tubulin antibody was used to perform western blot in order to study the role of E2f3b in in myogenic differentiation.
    • Sigma anti-alpha-tubulin antibody was used to perform immunoprecipitation and western blot in order to study the effect of Shp2 tyrosine phosphatase.