- Mary Johnson Ph. D.mary at labome dot comSynatom Research, Princeton, New Jersey, United States
If you are looking for Abcam antibodies against a specific gene, type in gene name in the box above and search. In the resultant gene webpage, select antibody link for the correct gene to go to the antibody webpage, and use "Abcam" filter as the supplier.
Abcam is a major supplier of research antibodies and associated reagents.
http://www.abcam.com/ in English.
Abcam maintains an international English language website from which users in most countries can select their country from a drop-down menu on the top right to select country-specific pricing and delivery information. For those countries to which Abcam does not ship directly, contact details are given for the local distributor.
Abcam also maintains regional Chinese and Japanese websites for customers located in these countries.
中文： http://www.abcam.cn/ in Chinese.
日本語： http://www.abcam.co.jp/ in Japanese.
Abcam has 8 offices globally. The following are details of key contact information. If your country is not listed here, please see the main international website here.
|location||phone and time||fax|
|United Kingdom (HQ)||+44(0)1223 email@example.com, firstname.lastname@example.org||fax: +44(0)1223 215215|
|United States||(888) 77-ABCAM (22226)||email@example.com, firstname.lastname@example.org||fax: (877) 774-8286, (617) 577-4201|
|China||108008523689, email@example.com, firstname.lastname@example.org||fax: (852) 3016-1888|
|Japan||+81(0)3 6231 email@example.com, firstname.lastname@example.org||fax: +81(0)3 6231 0941|
Abcam operates a total of 8 offices in the United Kingdom, United States, China and Japan. Abcam's headquarters is located at 330 Cambridge Science Park, Cambridge CB4 OF4, United Kingdom.
Based on its latest website update, Abcam offers over 100,000 products. This includes over 75,000 primary antibodies, over 2,700 secondary antibodies, over 10,000 proteins/protein fragments/peptides and some 2,000 cell/nuclear lysates. A range of over 600 bioactive small molecule reagents is available from AbcamBiochemicals. Abcam sources products from 400 suppliers worldwide. It also produces products in-house at 5 specialist production sites. According to abcam's 2012 annual report, 17% of total Group revenue came from products produced in-house. Although externally sourced reagents account for a very large proportion of Group revenue, approximately 80% of orders were fulfilled from held stock for same day dispatch. Primary antibody products accounted for over 88% of revenue during this same period. Abcam brand names include Abcam, Abcam Biochemicals, Epitomics and RabMab.
Europe: in-stock orders received by 4pm GMT Monday to Friday are dispatched the same day for next day delivery.
North America: in-stock orders received by 8pm EST Monday to Friday are dispatched the same day for next day delivery.
Technical support is available in English, Chinese, Japanese, French, German and Spanish.
Abcam maintains a poster library covering both general technical information and scientific information relevant to a range of areas (e.g. cancer, inflammation, cardiovascular, neuroscience, epigenetics, stem cells etc.).
Abcam also runs a number of webinars on techniques relevant to its products.
Abcam was formed in 1998 by Jonathan Milner, David Cleevely and Professor Tony Kouzarides FRS out of a lab at Cambridge University, UK. The principal founder, Jonathan Milner, is currently CEO.
Abcam plc is a public limited company incorporated in England & Wales. Abcam (Stock symbol: ABCA.L) trades on AIM, the London Stock Exchange's international market for smaller growing companies. Its annual revenue is nearly £98 million.
In May 2011, it acquired Mitosciences of Eugene, Oregon, a leading developer of antibodies and assays for mitochondrial research. In September 2011, Abcam acquired Ascent Biochemicals (now called AbcamBiochemicals) of Bristol, Uk, a specialist supplier of biochemical reagents including bioactive small molecules. In September 2012, Abcam acquired Epitomics of Burlingame, California. This has given Abcam access to Epitomics range of RabMAbs® rabbit monoclonal antibodies.
Abcam antibodies have been cited frequently in the literature. Labome manually reviews formal publications for information about antibody applications and about applications of other reagents and instruments. As of November 11, 2013, among the over 10100 publications that Labome reviewed, 888 publications cited antibody products from Abcam. The most frequently cited Abcam antibodies in the Labome publication database are listed in Table 2.
|Gene||Number of publications|
Abcam antibodies have been used in a range of applications as illustrated by the following examples. Abcam anti-H3K4me1 (catalog number: ab8895) and anti-H3K79me2 (catalog number: ab3594) antibodies were used to perform ChIP assays in order to show that gene transcription and chromatin remodelling change with the circadian clock in mammals . Abcam anti-Oct4 antibody (catalog number: ab19857) was used to probe western blots in experiments investigating the role of BRCA1 in the regulation of early embryogenesis . Abcam anti-H3 antibody (catalog number: ab1791) was used in western blotting experiments to study the role of histone H2A.X-F in modulating the cellular response to the rapid early cell cycles in externally developing species . Abcam CENP-F antibody (catalog number: ab90) was used in immunohistochemistry to study high CENP-F expression as a prognostic indicator of primary breast cancer . Abcam anti-pyruvate kinase antibody (catalog number: ab6191) was used to probe western blots in a proteomic study of keratinocytes after exposure to low doses arsenic and ionizing radiation . Abcam affinity purified rabbit polyclonal anti-BRCA2 antibody (catalog number: ab9143) was used in immunocytochemistry to study the interaction of the Fanconi anaemia protein FANCG with BRCA2/FANCD1 . Abcam anti-CD11b antibody was used in western blotting experiments to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the mass synthesis of secretory proteins . Abcam rabbit anti-GFP antibody (catalog number: ab6556) was used in immunohistochemistry to demonstrate that fetomaternal immune tolerance was regulated by epigenetic chemokine gene silencing in decidual stromal cells . Abcam anti-histone H1 antibody (catalog number: ab11079) was used to probe western blots in a study of the repair of DNA damaged by exposure to UV radiation .
Abcam's team of Ph.D. graduates attend a wide range of scientific meetings around the world to meet with the research community and stay up to date with the latest scientific developments. A list of the meetings that Abcam will be attending is available on the 'Events' tab of the abcam homepage. Abcam also invites requests from researchers to organise and co-chair scientific meetings (see: abcam tradeshow).
- Hussain S, Witt E, Huber P, Medhurst A, Ashworth A, Mathew C. Direct interaction of the Fanconi anaemia protein FANCG with BRCA2/FANCD1. Hum Mol Genet. 2003;12:2503-10 PMID 12915460
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