This is a review about Ppara, based on 21 published articles (read how Labome selects the articles), using Ppara antibody in all methods. It is aimed to help Labome visitors find the most suited Ppara antibody.
Ppara synonym: 4933429D07Rik; AW742785; Nr1c1; PPAR-alpha; PPARalpha; Ppar; nuclear receptor subfamily 1 group C member 1

Knockout validation
Rockland Immunochemicalsrabbit polyclonal
  • WB (knockout); mouse; 1:600; fig 3f
Rockland Immunochemicals Ppara antibody (Rockland, 600?C401-421) was used in western blot (knockout) on mouse samples at 1:600 (fig 3f). Proc Natl Acad Sci U S A (2015) ncbi
Abcam
rabbit polyclonal
  • WB; hamsters
Abcam Ppara antibody (Abcam, 8934) was used in western blot on hamsters samples. J Endocrinol (2015) ncbi
rabbit polyclonal
  • WB; mouse; 1:1000
Abcam Ppara antibody (Abcam, 24509) was used in western blot on mouse samples at 1:1000. Cardiovasc Diabetol (2015) ncbi
rabbit polyclonal
  • WB; mouse
Abcam Ppara antibody (Abcam, Ab24509) was used in western blot on mouse samples. BMC Endocr Disord (2015) ncbi
rabbit polyclonal
  • WB; mouse; fig 6b
In order to test the effects of high fat diet using a mouse model of familial Alzheimer disease, Abcam Ppara antibody (Abcam, Ab8934) was used in western blot on mouse samples (fig 6b). Biochim Biophys Acta (2015) ncbi
rabbit polyclonal
  • WB; rat
Abcam Ppara antibody (Abcam, ab24509) was used in western blot on rat samples. PLoS ONE (2014) ncbi
rabbit polyclonal
  • WB; rat; 1:500
Abcam Ppara antibody (Abcam, Ab24509) was used in western blot on rat samples at 1:500. Endocrinology (2014) ncbi
rabbit polyclonal
  • WB; human; 1:500
  • WB; rat; 1:500
Abcam Ppara antibody (Abcam, ab8934) was used in western blot on human samples at 1:500 and on rat samples at 1:500. Br J Pharmacol (2013) ncbi
rabbit polyclonal
  • IHC-P; rat; 1:500
Abcam Ppara antibody (Abcam, ab24509) was used in immunohistochemistry - paraffin section on rat samples at 1:500. Toxicol Sci (2013) ncbi
not indicated
  • WB; mouse
ABCAM anti-PPAR alpha antibody was used to perform western blot in order to study the role of adenosine signaling in ethanol-induced fatty liver.J Clin Invest (2009) ncbi
Santa Cruz Biotechnology
rabbit polyclonal (H-98)
  • WB; mouse
In order to study the regulatory effect of a high-fish-oil diet on rodent white adipose tissue inflammation pathways, Santa Cruz Biotechnology Ppara antibody (Santa Cruz, SC-9000) was used in western blot on mouse samples. J Nutr Biochem (2015) ncbi
goat polyclonal (N-19)
  • IHC-P; human; 1:100
Santa Cruz Biotechnology Ppara antibody (Santa Cruz Biotechnology, sc 1985) was used in immunohistochemistry - paraffin section on human samples at 1:100. J Dermatol (2015) ncbi
rabbit polyclonal (H-98)
  • WB; rat
In order to study the effect of palmitate on cytokine and PPAR activity/expression in primary rat neonatal cardiomyocytes, Santa Cruz Biotechnology Ppara antibody (Santa Cruz, SC-9000) was used in western blot on rat samples. Biochem Biophys Res Commun (2015) ncbi
goat polyclonal (N-19)
  • WB; rat
  • IC; rat
Santa Cruz Biotechnology Ppara antibody (Santa Cruz Biotechnology, sc-1985) was used in western blot on rat samples and in immunocytochemistry on rat samples. Reprod Toxicol (2014) ncbi
rabbit polyclonal (H-98)
  • IHC; rat; 1:100
  • WB; rat; 1:200
Santa Cruz Biotechnology Ppara antibody (Santa Cruz Biotechnology Inc., sc-9000) was used in immunohistochemistry on rat samples at 1:100 and in western blot on rat samples at 1:200. Neuroscience (2014) ncbi
rabbit polyclonal (H-98)
  • IHC; mouse
  • IHC; rat
Santa Cruz Biotechnology Ppara antibody (Santa Cruz Biotechnology, H-98) was used in immunohistochemistry on mouse samples and on rat samples. J Biol Chem (2014) ncbi
Invitrogen
rabbit polyclonal
  • WB; mouse
In order to investigate the role of L-FABP and SCP-2/SCP-x in hepatic lipid metabolism, Invitrogen Ppara antibody (Pierce, PA1-822A) was used in western blot on mouse samples. Arch Biochem Biophys (2015) ncbi
rabbit polyclonal
  • WB; mouse
In order to investigate the role of SCP-2/SCP-x and dietary cholesterol in hepatic lipid metabolism, Invitrogen Ppara antibody (ThermoFisher Scientific, PA1-822A) was used in western blot on mouse samples. Am J Physiol Gastrointest Liver Physiol (2015) ncbi
rabbit polyclonal
  • WB; mouse; 1:1000
In order to study the mechanisms underlying the beneficial effects of a dietary pine bark extract on glucose tolerance in a murine model of type 2 diabetes, Invitrogen Ppara antibody (Thermo Scientific, PA1-822A) was used in western blot on mouse samples at 1:1000. J Pharm Pharmacol (2014) ncbi
Rockland Immunochemicals
rabbit polyclonal
  • WB (knockout); mouse; 1:600; fig 3f
Rockland Immunochemicals Ppara antibody (Rockland, 600?C401-421) was used in western blot (knockout) on mouse samples at 1:600 (fig 3f). Proc Natl Acad Sci U S A (2015) ncbi
EMD Millipore
rabbit polyclonal
  • EMSA; human
In order to study the regulation of brown adipocyte UCP3 transcription by a novel intronic enhancer that binds SP1 and SP3, EMD Millipore Ppara antibody (Millipore, 07-466) was used in EMSA on human samples. PLoS ONE (2013) ncbi
Sigma-Aldrich
rabbit polyclonal
  • WB; mouse; fig 4
In order to study the protective effects against cardiac steatosis and dilated cardiomyopathy of specifically overexpressing triglyceride lipase in cardiomyocytes in a murine model of diet-induced obesity, Sigma-Aldrich Ppara antibody (Sigma, P0369) was used in western blot on mouse samples (fig 4). Int J Obes (Lond) (2014) ncbi
Articles Reviewed
  1. Ricardo J Samms et al. (2015). "Dual effects of fibroblast growth factor 21 on hepatic energy metabolism".PMID 26294388
  2. Jun He et al. (2015). "MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet".PMID 26242235
  3. Megan T Quintana et al. (2015). "Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet".PMID 26215257
  4. Gregory G Martin et al. (2015). "Loss of L-FABP, SCP-2/SCP-x, or both induces hepatic lipid accumulation in female mice".PMID 26116377
  5. Devon Klipsic et al. (2015). "Impact of SCP-2/SCP-x gene ablation and dietary cholesterol on hepatic lipid accumulation".PMID 26113298
  6. Grant T Corbett et al. (2015). "Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP".PMID 26080426
  7. Dmitry Petrov et al. (2015). "High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents".PMID 26003667
  8. Thereza Cristina Lonzetti Bargut et al. (2015). "A high-fish-oil diet prevents adiposity and modulates white adipose tissue inflammation pathways in mice".PMID 25997866
  9. Rana M Elewa et al. (2015). "Age-associated skin changes in innate immunity markers reflect a complex interaction between aging mechanisms in the sebaceous gland".PMID 25818897
  10. Taha Haffar et al. (2015). "Cardiomyocyte lipotoxicity is mediated by Il-6 and causes down-regulation of PPARs".PMID 25712520
  11. Xi Zhang et al. (2014). "Inhibition of PPARα attenuates vimentin phosphorylation on Ser-83 and collapse of vimentin filaments during exposure of rat Sertoli cells in vitro to DBP".PMID 25291543
  12. J Wang et al. (2014). "Down-regulation of PPARα in the spinal cord contributes to augmented peripheral inflammation and inflammatory hyperalgesia in diet-induced obese rats".PMID 25135355
  13. Frits Mattijssen et al. (2014). "Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion".PMID 24876382
  14. Chae Young Bang et al. (2014). "Enzogenol improves diabetes-related metabolic change in C57BL/KsJ-db/db mice, a model of type 2 diabetes mellitus".PMID 24611864
  15. Bradley Carrier et al. (2014). "Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats".PMID 24595397
  16. Christoph Hoffmann et al. (2013). "A novel SP1/SP3 dependent intronic enhancer governing transcription of the UCP3 gene in brown adipocytes".PMID 24391766
  17. L Nikolaenko et al. (2014). "Testosterone replacement ameliorates nonalcoholic fatty liver disease in castrated male rats".PMID 24280056
  18. T Pulinilkunnil et al. (2014). "Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity".PMID 23817015
  19. Wei Wang et al. (2013). "Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats".PMID 23647015
  20. Simon M Plummer et al. (2013). "Identification of transcription factors and coactivators affected by dibutylphthalate interactions in fetal rat testes".PMID 23358192
  21. Zhongsheng Peng et al. (2009). "Adenosine signaling contributes to ethanol-induced fatty liver in mice".PMID 19221436