This is a review about Pax2, based on 48 published articles (read how Labome selects the articles), using Pax2 antibody in all methods. It is aimed to help Labome visitors find the most suited Pax2 antibody.
Pax2 synonym: Opdc; Pax-2; optic disc coloboma; paired box gene 2

Invitrogen
rabbit polyclonal
  • IC; human; 1:300
In order to evaluate the kidney organoids from human iPS cells, Invitrogen Pax2 antibody (Zymed, 71-6,000) was used in immunocytochemistry on human samples at 1:300. Nature (2015) ncbi
rabbit polyclonal
  • IHC; mouse; 1:200
In order to describe a novel type of kidney cell, Invitrogen Pax2 antibody (Zymed Labs., 71-6000) was used in immunohistochemistry on mouse samples at 1:200. Cell Tissue Res (2016) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:500
In order to investigate how PNKP inactivation impacts neurogenesis, Invitrogen Pax2 antibody (Zymed, cat# 71-6000) was used in immunohistochemistry - frozen section on mouse samples at 1:500. EMBO J (2015) ncbi
rabbit polyclonal
  • IHC; mouse; 1:200
In order to examine Klf4 expression in embryonic development of the normal and Klf4 knockout cerebellum, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry on mouse samples at 1:200. PLoS ONE (2015) ncbi
rabbit polyclonal
  • IHC-P; mouse; 1:200
In order to study kidney development in Robo2 mouse mutants, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry - paraffin section on mouse samples at 1:200. Dev Biol (2015) ncbi
rabbit polyclonal
  • IHC; mouse; 1:500; fig 4
In order to investigate the role of Sox-9 in the maintenance and fate decision of the neural progenitor pool in the cerebellum, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry on mouse samples at 1:500 (fig 4). Mol Brain (2015) ncbi
rabbit polyclonal
  • IHC-P; mouse; 1:5
In order to determine the origin of the rostral Substantia nigra pars reticulata, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry - paraffin section on mouse samples at 1:5. Brain Struct Funct (2016) ncbi
rabbit polyclonal
  • IHC; mouse; 1:1000
In order to compare the localization of gastrin-releasing peptide immunoreactivity to primary afferent or excitatory interneuron terminals, Invitrogen Pax2 antibody (Life Technologies, 716000) was used in immunohistochemistry on mouse samples at 1:1000. Mol Pain (2014) ncbi
rabbit polyclonal
  • IHC; mouse; 1:200
In order to investigate mechanisms by which organs coordinate their size and shape, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry on mouse samples at 1:200. Dev Biol (2014) ncbi
not indicated
  • IHC; mouse
Invitrogen anti-Pax2 was used to perform immunohistochemistry in order to study the regulation of retinal axon growth by secreted Vax1 homeodomain protein.elife (2014) ncbi
rabbit polyclonal
  • IC; mouse; 1:1000; fig 3
In order to elucidate the roles of Ascl1 and Ptf1a in neuronal development, Invitrogen Pax2 antibody (Life Technologies, 71-6000) was used in immunocytochemistry on mouse samples at 1:1000 (fig 3). Development (2014) ncbi
rabbit polyclonal
  • IHC; mouse; 1:100
In order to determine the function of Msx genes in the spinal cord, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry on mouse samples at 1:100. Development (2014) ncbi
rabbit polyclonal
  • IHC; mouse; 1:1000; fig s6
In order to identify a population of motor synergy encoder neurons in the mouse spinal cord that may represent a central node in neural pathways for voluntary and reflexive movement, Invitrogen Pax2 antibody (Invitrogen, 716000) was used in immunohistochemistry on mouse samples at 1:1000 (fig s6). Nat Neurosci (2014) ncbi
rabbit polyclonal
  • IC; human; 1:200; fig 3
In order to describe a protocol for pluripotent-stem-cell-based renal regeneration, Invitrogen Pax2 antibody (Zymed, 71-6,000) was used in immunocytochemistry on human samples at 1:200 (fig 3). Nat Cell Biol (2014) ncbi
rabbit polyclonal
  • IHC; mouse; 1:400; fig 2, 3
In order to test if cell-autonomous Otx2 is required to control the identity and fate of dorsal mesencephalic progenitors, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry on mouse samples at 1:400 (fig 2, 3). Development (2014) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:1000; fig 1
In order to describe a combinatorial transcription factor code that defines nine different inhibitory and excitatory interneuron populations in laminae III-IV of the postnatal cord, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 1). PLoS ONE (2013) ncbi
rabbit polyclonal
  • IHC-P; mouse; 1:200
In order to examine the role of chromatin modification in nephrogenesis, Invitrogen Pax2 antibody (Invitrogen, 71?C6000) was used in immunohistochemistry - paraffin section on mouse samples at 1:200. Epigenetics (2014) ncbi
rabbit polyclonal
  • IHC; mouse; fig 3
In order to examine the proximal nephron response to unilateral ureteral obstruction in the maturing kidney, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry on mouse samples (fig 3). Am J Physiol Renal Physiol (2013) ncbi
rabbit polyclonal
  • IHC-P; human; 1:100
In order to identify the origin of ovarian Brenner tumour, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry - paraffin section on human samples at 1:100. Eur J Cancer (2013) ncbi
rabbit polyclonal
  • IHC; mouse
In order to study the function of cerebellins in the cerebellum and striatum, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry on mouse samples. J Comp Neurol (2014) ncbi
rabbit polyclonal
  • IHC-Free; mouse; 1:500
In order to examine the functions of Smad proteins during cerebellum development, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry - free floating section on mouse samples at 1:500. Mol Cell Biol (2013) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:100; fig 4
In order to investigate cellular pathogenesis of GM2 gangliosidosis, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 4). PLoS Genet (2012) ncbi
rabbit polyclonal
  • IHC-P; mouse; fig 2
In order to describe three methods for re-constructing mouse fetal kidney tissue, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry - paraffin section on mouse samples (fig 2). Methods Mol Biol (2012) ncbi
rabbit polyclonal
  • WB; mouse; 1:500; fig 5
  • IC; mouse; 1:50; fig 5
In order to examine the morphology of primary glomerular epithelial cells, Invitrogen Pax2 antibody (Invitrogen, 716000) was used in western blot on mouse samples at 1:500 (fig 5) and in immunocytochemistry on mouse samples at 1:50 (fig 5). PLoS ONE (2012) ncbi
rabbit polyclonal
  • IHC-P; mouse; fig 3
In order to study the antagonization of BMP signaling by Fstl1 and the significance for normal development of the ureter, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry - paraffin section on mouse samples (fig 3). PLoS ONE (2012) ncbi
rabbit polyclonal
  • IC; mouse; fig 6
In order to study the Wnt1 expressing progenitors in the rhombomere 1, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunocytochemistry on mouse samples (fig 6). Mol Cell Neurosci (2012) ncbi
rabbit polyclonal
  • WB; human; fig 6
In order to study the role and regulation of PAX2 in the control of luminal breast cancer invasion, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in western blot on human samples (fig 6). Mol Cancer (2011) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:200; fig 2
In order to describe a transcriptional program that controls Renshaw cell differentiation, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 2). Development (2012) ncbi
rabbit polyclonal
  • IHC; mouse; 1:750
In order to report a role for MMP-3 in the histogenesis of the mouse cerebellar cortex, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry on mouse samples at 1:750. Mol Neurobiol (2012) ncbi
rabbit polyclonal
  • IHC; mouse; 1:1000; fig 2
In order to show a role for KLF5 in the formation and terminal differentiation of the urothelium, Invitrogen Pax2 antibody (Invitrogen, 716000) was used in immunohistochemistry on mouse samples at 1:1000 (fig 2). Dev Biol (2011) ncbi
rabbit polyclonal
  • IHC; mouse; tbl 1
In order to use transgenic zebrafish to study Pax8 localization and function, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry on mouse samples (tbl 1). J Comp Neurol (2011) ncbi
rabbit polyclonal
  • IHC-Free; mouse; 1:200
In order to investigate the migration and maturation of neurogenin1 neurons in the rodent central nervous system, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry - free floating section on mouse samples at 1:200. J Comp Neurol (2011) ncbi
rabbit polyclonal
  • WB; mouse; fig 1
In order to report that Lig3 is essential for mitochondrial DNA integrity but dispensable for nuclear DNA repair, Invitrogen Pax2 antibody (Zymed, 71?C6000) was used in western blot on mouse samples (fig 1). Nature (2011) ncbi
rabbit polyclonal
  • IHC-P; mouse; fig 1
In order to study the role of non-canonical Calcium/NFAT Wnt signaling in nephrogenesis, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry - paraffin section on mouse samples (fig 1). Dev Biol (2011) ncbi
rabbit polyclonal
  • IHC-F; zebrafish; 1:400; fig 2
In order to characterize the spatio-temporal patterns of regulatory elements in the pou3f4 locus using zebrafish, Invitrogen Pax2 antibody (Zymed laboratories, 71-6000) was used in immunohistochemistry - frozen section on zebrafish samples at 1:400 (fig 2). PLoS ONE (2010) ncbi
rabbit polyclonal
  • IHC-P; human; 1:100; fig 2
In order to characterize multilocular cystic renal cell carcinoma samples, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2). Mod Pathol (2011) ncbi
rabbit polyclonal
  • IHC-P; human; fig 4
In order to examine p53 and PAX2 in all secretory cell outgrowths, Invitrogen Pax2 antibody (Invitrogen, 71-6000) was used in immunohistochemistry - paraffin section on human samples (fig 4). J Pathol (2010) ncbi
rabbit polyclonal
  • IHC-P; chicken; 1:500
In order to identify cerebellin2 in chick and study its expression pattern, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry - paraffin section on chicken samples at 1:500. J Comp Neurol (2010) ncbi
rabbit polyclonal
  • IHC-F; mouse
In order to exmaine the role of Cdk5 in the neurnal migration in the developing spinal cord, Invitrogen Pax2 antibody (Zymed Laboratories, 71-6000) was used in immunohistochemistry - frozen section on mouse samples. J Comp Neurol (2007) ncbi
rabbit polyclonal
  • IHC-P; human; 10 ug/ml; fig 6
  • WB; human; 1:1000; fig 3
In order to assess the pattern and requirement for PAX gene expression in a panel of common cancer cell lines, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry - paraffin section on human samples at 10 ug/ml (fig 6) and in western blot on human samples at 1:1000 (fig 3). Oncogene (2003) ncbi
rabbit polyclonal
  • IHC; mouse; fig 5
In order to investigate the role of JSAP1 in early embryonic neurogenesis, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in immunohistochemistry on mouse samples (fig 5). J Biol Chem (2003) ncbi
rabbit polyclonal
  • IHC-P; human
In order to examine the developing urinary tract in individuals with Kallmann's syndrome, Invitrogen Pax2 antibody (Zymed, 71?C6000) was used in immunohistochemistry - paraffin section on human samples. Nephrol Dial Transplant (2001) ncbi
rabbit polyclonal
  • WB; human
In order to investigate the role of TGF-beta1 in the pathobiology of dysplastic kidneys, Invitrogen Pax2 antibody (Zymed, 71-6000) was used in western blot on human samples. Am J Pathol (2000) ncbi
BioLegend
rabbit polyclonal (Poly19010)
  • IHC-F; common platanna; 1:200
BioLegend Pax2 antibody (Covance, PRB-276P) was used in immunohistochemistry - frozen section on common platanna samples at 1:200. Dev Biol (2015) ncbi
rabbit polyclonal (Poly19010) BioLegend Pax2 antibody (COVANCE, PRB-276P) was used . Dev Dyn (2012) ncbi
not indicated
  • IHC; mouse
Covance anti-Pax-2 antibody was used in immunohistochemistry to stain for Pax-2 in mouse early developing nephrons and ureteric budsJ Biol Chem (2006) ncbi
Santa Cruz Biotechnology
mouse monoclonal (60-P)
  • WB; rat
Santa Cruz Biotechnology Pax2 antibody (Santa Cruz Biotechnology, sc-130387) was used in western blot on rat samples. Redox Biol (2014) ncbi
Cambridge Bioscience
not indicated
  • IHC; mouse
Cambridge Bioscience anti-Pax2 antibody was used in immunohistochemistry to examine the consequences of over-expression of Pax6 for the eye and its axonal connections.BMC Dev Biol (2008) ncbi
Articles Reviewed
  1. Minoru Takasato et al. (2015). "Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis".PMID 26444236
  2. M S Forbes et al. (2016). "A population of mitochondrion-rich cells in the pars recta of mouse kidney".PMID 26337515
  3. Mikio Shimada et al. (2015). "Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability".PMID 26290337
  4. Peter Zhang et al. (2015). "Kruppel-Like Factor 4 Regulates Granule Cell Pax6 Expression and Cell Proliferation in Early Cerebellar Development".PMID 26226504
  5. Elanor N Wainwright et al. (2015). "ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation".PMID 26116176
  6. Keng Ioi Vong et al. (2015). "Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum".PMID 25888505
  7. M Pilar Madrigal et al. (2016). "Mesencephalic origin of the rostral Substantia nigra pars reticulata".PMID 25579066
  8. MarĂ­a Gutierrez-Mecinas et al. (2014). "Expression of gastrin-releasing peptide by excitatory interneurons in the mouse superficial dorsal horn".PMID 25496164
  9. Joseph Fomusi Ndisang et al. (2014). "Mechanisms by which heme oxygenase rescue renal dysfunction in obesity".PMID 25460740
  10. Isabelle Buisson et al. (2015). "Pax8 and Pax2 are specifically required at different steps of Xenopus pronephros development".PMID 25446030
  11. Elanor N Wainwright et al. (2014). "Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice".PMID 25224227
  12. Namsuk Kim et al. (2014). "Regulation of retinal axon growth by secreted Vax1 homeodomain protein".PMID 25201875
  13. Mark D Borromeo et al. (2014). "A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord".PMID 24924197
  14. Nathalie Duval et al. (2014). "Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord".PMID 24715462
  15. Ariel J Levine et al. (2014). "Identification of a cellular node for motor control pathways".PMID 24609464
  16. M Takasato et al. (2014). "Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney".PMID 24335651
  17. Luca G Di Giovannantonio et al. (2014). "Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity".PMID 24335253
  18. Marta Garcia Del Barrio et al. (2013). "A transcription factor code defines nine sensory interneuron subtypes in the mechanosensory area of the spinal cord".PMID 24223744
  19. Nathan McLaughlin et al. (2014). "In situ histone landscape of nephrogenesis".PMID 24169366
  20. Michael S Forbes et al. (2013). "Chronic unilateral ureteral obstruction in the neonatal mouse delays maturation of both kidneys and leads to late formation of atubular glomeruli".PMID 24107422
  21. Elisabetta Kuhn et al. (2013). "Ovarian Brenner tumour: a morphologic and immunohistochemical analysis suggesting an origin from fallopian tube epithelium".PMID 24012099
  22. Michael C Cagle et al. (2014). "Parcellation of cerebellins 1, 2, and 4 among different subpopulations of dorsal horn neurons in mouse spinal cord".PMID 23853053
  23. Ka Kui Tong et al. (2013). "Common partner Smad-independent canonical bone morphogenetic protein signaling in the specification process of the anterior rhombic lip during cerebellum development".PMID 23459943
  24. Timothy J Sargeant et al. (2012). "Characterization of inducible models of Tay-Sachs and related disease".PMID 23028353
  25. Jamie A Davies et al. (2012). "Dissociation of embryonic kidney followed by re-aggregation as a method for chimeric analysis".PMID 22639257
  26. Nazanin Kabgani et al. (2012). "Primary cultures of glomerular parietal epithelial cells or podocytes with proven origin".PMID 22529955
  27. Jingyue Xu et al. (2012). "Fstl1 antagonizes BMP signaling and regulates ureter development".PMID 22485132
  28. Nellwyn Hagan et al. (2012). "Wnt1 expression temporally allocates upper rhombic lip progenitors and defines their terminal cell fate in the cerebellum".PMID 22173107
  29. David Beauchemin et al. (2011). "PAX2 is activated by estradiol in breast cancer cells of the luminal subgroup selectively, to confer a low invasive phenotype".PMID 22168360
  30. Kazuhide Asakawa et al. (2012). "An mnr2b/hlxb9lb enhancer trap line that labels spinal and abducens motor neurons in zebrafish".PMID 22128106
  31. Floor J Stam et al. (2012). "Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program".PMID 22115757
  32. Inge Van Hove et al. (2012). "An aberrant cerebellar development in mice lacking matrix metalloproteinase-3".PMID 22108898
  33. Sheila M Bell et al. (2011). "Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium".PMID 21803035
  34. Takanori Ikenaga et al. (2011). "Formation of the spinal network in zebrafish determined by domain-specific pax genes".PMID 21452218
  35. Euiseok J Kim et al. (2011). "Spatiotemporal fate map of neurogenin1 (Neurog1) lineages in the mouse central nervous system".PMID 21452201
  36. Yankun Gao et al. (2011). "DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair".PMID 21390131
  37. S F Burn et al. (2011). "Calcium/NFAT signalling promotes early nephrogenesis".PMID 21295565
  38. Alex Robert-Moreno et al. (2010). "Characterization of new otic enhancers of the pou3f4 gene reveal distinct signaling pathway regulation and spatio-temporal patterns".PMID 21209840
  39. Adriana von Teichman et al. (2011). "VHL mutations and dysregulation of pVHL- and PTEN-controlled pathways in multilocular cystic renal cell carcinoma".PMID 21151099
  40. Eleanor Y Chen et al. (2010). "Secretory cell outgrowth, PAX2 and serous carcinogenesis in the Fallopian tube".PMID 20597068
  41. Mao Yang et al. (2010). "Identification of cerebellin2 in chick and its preferential expression by subsets of developing sensory neurons and their targets in the dorsal horn".PMID 20506477
  42. Martine Manuel et al. (2008). "Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance".PMID 18507827
  43. Yee Ping Yip et al. (2007). "Cdk5 selectively affects the migration of different populations of neurons in the developing spinal cord".PMID 17492640
  44. Chin Tong Ong et al. (2006). "Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability".PMID 16365048
  45. Aleksandra Muratovska et al. (2003). "Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival".PMID 12970747
  46. Ping Xu et al. (2003). "In vitro development of mouse embryonic stem cells lacking JNK/stress-activated protein kinase-associated protein 1 (JSAP1) scaffold protein revealed its requirement during early embryonic neurogenesis".PMID 12968026
  47. A Deeb et al. (2001). "Multicystic dysplastic kidney and Kallmann's syndrome: a new association?".PMID 11390716
  48. S P Yang et al. (2000). "Potential biological role of transforming growth factor-beta1 in human congenital kidney malformations".PMID 11073823