This is a review about Mcl1, based on 30 published articles (read how Labome selects the articles), using Mcl1 antibody in all methods. It is aimed to help Labome visitors find the most suited Mcl1 antibody.
Mcl1 synonym: AW556805; Mcl-1; bcl-2-related protein EAT/mcl1

Santa Cruz Biotechnology
rabbit polyclonal (S-19)
  • IC; mouse
In order to investigate the role of MCL-1 in oocyte survival, Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz Biotechnologies, sc-819) was used in immunocytochemistry on mouse samples. Cell Death Dis (2015) ncbi
mouse monoclonal (RC13)
  • WB; human
In order to assess the effect of matrine on STAT3 signaling in cholangiocarcinoma cells, Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz, sc-56152) was used in western blot on human samples. Pharmacol Rep (2015) ncbi
rabbit polyclonal (S-19)
  • WB; human; 1:700
Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz Biotechnology, (sc-819) was used in western blot on human samples at 1:700. Chem Biol Interact (2015) ncbi
rabbit polyclonal (S-19)
  • WB; human; fig 2c
Santa Cruz Biotechnology Mcl1 antibody (Santa, sc-819) was used in western blot on human samples (fig 2c). Cell (2014) ncbi
rabbit polyclonal (S-19)
  • WB; mouse; 1:500-1:1000; fig s1f
In order to elucidate the regulation of Notch by Cyclin C, Santa Cruz Biotechnology Mcl1 antibody (Santa, sc-819) was used in western blot on mouse samples at 1:500-1:1000 (fig s1f). Nat Cell Biol (2014) ncbi
rabbit polyclonal (S-19)
  • WB; human
Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz Biotechnology, sc-819) was used in western blot on human samples. J Natl Cancer Inst (2014) ncbi
rabbit polyclonal (S-19)
  • WB; human
Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz Biotechnology, sc-819) was used in western blot on human samples. Cell Death Differ (2014) ncbi
rabbit polyclonal (S-19)
  • IHC; human; 1:800
In order to study treatment resistance mechanisms in triple-negative breast cancers, Santa Cruz Biotechnology Mcl1 antibody (Santa, sc-819) was used in immunohistochemistry on human samples at 1:800. Cancer Discov (2014) ncbi
rabbit polyclonal (S-19)
  • WB; human; 1:200
  • IC; human; 1:100
In order to investigate the signaling events in pregnant and postnatal uteri of mice and baboons, Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz Biotech, SC-819) was used in western blot on human samples at 1:200 and in immunocytochemistry on human samples at 1:100. Endocrinology (2013) ncbi
rabbit polyclonal (S-19)
  • WB; mouse; 1:1000
Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz, sc-819) was used in western blot on mouse samples at 1:1000. Hepatology (2013) ncbi
rabbit polyclonal (S-19)
  • WB; human; 1:500
Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz, sc-819) was used in western blot on human samples at 1:500. PLoS ONE (2013) ncbi
rabbit polyclonal (S-19)
  • WB; human
  • WB; mouse
Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz Biotechnology, sc-819) was used in western blot on human samples and on mouse samples. Cell Death Dis (2013) ncbi
rabbit polyclonal (S-19)
  • WB; human; 1:1000
Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz Biotechnology, sc-819) was used in western blot on human samples at 1:1000. Leuk Res (2012) ncbi
not indicated
  • WB; mouse
Santa Cruz anti-MCL-1 antibody was used in western blot in order to investigate the role of BID, BIM, and PUMA in activating the BAX- and BAK-dependent cell death program.Science (2010) ncbi
rabbit polyclonal (S-19)
  • WB; human; 1:200
Santa Cruz Biotechnology Mcl1 antibody (Santa Cruz Biotechnology, sc-819) was used in western blot on human samples at 1:200. Gut (2007) ncbi
Abcam
rabbit monoclonal (Y37)
  • WB; human; 1:1000
Abcam Mcl1 antibody (Abcam, ab32087) was used in western blot on human samples at 1:1000. Apoptosis (2014) ncbi
rabbit monoclonal (Y37)
  • WB; human; 1:500
Abcam Mcl1 antibody (Abcam, ab32087) was used in western blot on human samples at 1:500. Autophagy (2013) ncbi
not indicated
  • WB; mouse
Abcam antibody against mouse Mcl1 was used in western blot to detect Mcl1 in mouse embryo fibroblasts (MEFs).Genes Dev (2008) ncbi
Rockland Immunochemicals
rabbit polyclonal
  • WB; mouse
In order to study the effect of parkin deletion and acute knockdown on acetaminophen-induced mitophagy and liver injury in mice, Rockland Immunochemicals Mcl1 antibody (Rockland, 600-401-394) was used in western blot on mouse samples. J Biol Chem (2015) ncbi
rabbit polyclonal
  • WB; mouse
Rockland Immunochemicals Mcl1 antibody (Rockland Immunochemicals, 600-401-394) was used in western blot on mouse samples. Methods Enzymol (2009) ncbi
not indicated
  • WB; mouse
Rockland rabbit polyclonal anti-Mcl-1 was used to perform western blot in order to demonstrate that Puma imposes a significant, and Noxa a minor barrier to c-Myc-driven lymphomagenesisCell Death Differ (2009) ncbi
not indicated
  • WB; mouse
Rockland Immunochemical rabbit polyclonal anti-MCL-1 was used to perform western blot in order to illustrate the importance of Mcl-1 in granulocyte development and macrophage effector function.Blood (2009) ncbi
Cell Signaling Technology
rabbit monoclonal (D35A5)
  • WB; human; fig 5
In order to elucidate how PLK1 regulates cell survival during mTORC1 hyperactivation, Cell Signaling Technology Mcl1 antibody (Cell signaling, 5453) was used in western blot on human samples (fig 5). Cell Cycle (2015) ncbi
rabbit monoclonal (D35A5)
  • WB; human
Cell Signaling Technology Mcl1 antibody (Cell Signaling Technology, 5453) was used in western blot on human samples. Mol Cell Biol (2014) ncbi
rabbit monoclonal (D35A5)
  • WB; human
Cell Signaling Technology Mcl1 antibody (Cell Signaling Technologies, 5453) was used in western blot on human samples. PLoS ONE (2014) ncbi
rabbit monoclonal (D35A5)
  • WB; mouse
Cell Signaling Technology Mcl1 antibody (Cell Signaling Technology, 5453) was used in western blot on mouse samples. J Neurosci (2013) ncbi
rabbit monoclonal (D35A5)
  • WB; mouse
Cell Signaling Technology Mcl1 antibody (Cell Signaling, D35A5) was used in western blot on mouse samples. Mol Cancer Ther (2013) ncbi
rabbit monoclonal (D35A5)
  • WB; human
Cell Signaling Technology Mcl1 antibody (Cell Signaling, 5453) was used in western blot on human samples. Cell Cycle (2013) ncbi
not indicated
  • WB; mouse
Cell Signaling Technology Bcl-2 antibody was used in western blot in order to suggest that targeting of NF-kappa B signaling can contribute to increase the yield of milk.J Cell Physiol (2010) ncbi
Abgent
not indicated
  • WB; mouse
Abgent anti-Mcl-1 antibody was used to perform western blot in order to stduy TCL-1 transgenic mouse is a approach for screen new drugs for CLL.Blood (2006) ncbi
Articles Reviewed
  1. S Omari et al. (2015). "Mcl-1 is a key regulator of the ovarian reserve".PMID 25950485
  2. Jessica A Williams et al. (2015). "Chronic Deletion and Acute Knockdown of Parkin Have Differential Responses to Acetaminophen-induced Mitophagy and Liver Injury in Mice".PMID 25752611
  3. Nanmu Yang et al. (2015). "Matrine suppresses proliferation and induces apoptosis in human cholangiocarcinoma cells through suppression of JAK2/STAT3 signaling".PMID 25712669
  4. Min Ae Han et al. (2015). "6-Shogaol enhances renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated cytochrome c release and down-regulation of c-FLIP(L) expression".PMID 25619640
  5. Matthildi Valianou et al. (2015). "Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy".PMID 25565629
  6. Edmond Chipumuro et al. (2014). "CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer".PMID 25416950
  7. Na Li et al. (2014). "Cyclin C is a haploinsufficient tumour suppressor".PMID 25344755
  8. Iraz T Aydin et al. (2014). "FBXW7 mutations in melanoma and a new therapeutic paradigm".PMID 24838835
  9. S C Cazanave et al. (2014). "Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis".PMID 24769730
  10. Matthew S Waitkus et al. (2014). "Signal integration and gene induction by a functionally distinct STAT3 phosphoform".PMID 24615012
  11. Heejei Yoon et al. (2014). "Targeted inhibition of FAK, PYK2 and BCL-XL synergistically enhances apoptosis in ovarian clear cell carcinoma cell lines".PMID 24523919
  12. Alessandro Annibaldi et al. (2014). "TAT-RasGAP317-326-mediated tumor cell death sensitization can occur independently of Bax and Bak".PMID 24362790
  13. Justin M Balko et al. (2014). "Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets".PMID 24356096
  14. Andrew J Crowther et al. (2013). "Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma".PMID 24227720
  15. Yuan Fei Peng et al. (2013). "Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells".PMID 24157892
  16. Chandrashekara Kyathanahalli et al. (2013). "Cross-species withdrawal of MCL1 facilitates postpartum uterine involution in both the mouse and baboon".PMID 24140717
  17. Christian D Fingas et al. (2013). "Polo-like kinase 2 is a mediator of hedgehog survival signaling in cholangiocarcinoma".PMID 23703673
  18. Tian Ma et al. (2013). "Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer".PMID 23686769
  19. Ryan C Thompson et al. (2013). "The sensitivity of diffuse large B-cell lymphoma cell lines to histone deacetylase inhibitor-induced apoptosis is modulated by BCL-2 family protein activity".PMID 23667527
  20. M A Mobasher et al. (2013). "Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity".PMID 23661004
  21. Elisa Carra et al. (2013). "Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures".PMID 23324350
  22. Patricia Balsas et al. (2012). "Bortezomib resistance in a myeloma cell line is associated to PSMβ5 overexpression and polyploidy".PMID 21978467
  23. Decheng Ren et al. (2010). "BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program".PMID 21127253
  24. Linda Connelly et al. (2010). "Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection".PMID 19746431
  25. Ji Zhang et al. (2009). "Mitophagy in mammalian cells: the reticulocyte model".PMID 19200886
  26. E M Michalak et al. (2009). "Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis".PMID 19148184
  27. Desiree A Steimer et al. (2009). "Selective roles for antiapoptotic MCL-1 during granulocyte development and macrophage effector function".PMID 19064728
  28. Konstantinos J Mavrakis et al. (2008). "Tumorigenic activity and therapeutic inhibition of Rheb GTPase".PMID 18708578
  29. Harmeet Malhi et al. (2007). "Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity".PMID 17470478
  30. Amy J Johnson et al. (2006). "Characterization of the TCL-1 transgenic mouse as a preclinical drug development tool for human chronic lymphocytic leukemia".PMID 16670263