This is a review about Cdkn2a, based on 18 published articles (read how Labome selects the articles), using Cdkn2a antibody in all methods. It is aimed to help Labome visitors find the most suited Cdkn2a antibody.
Cdkn2a synonym: ARF-INK4a; Arf; INK4a-ARF; Ink4a/Arf; MTS1; Pctr1; p16; p16(INK4a); p16INK4a; p19; p19ARF; CDK4I; cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; mitochondrial smARF; p16-INK4; p16-INK4a

Santa Cruz BiotechnologySanta Cruz Biotechnology Cdkn2a product
  • immunocytochemistryIn 2005, I Ching Wang et al. applied Santa Cruz Biotechnology Cdkn2a antibody to study the function of forkhead box M1 to regulate the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase [ncbi , more ].
  • immunohistochemistryIn 2010, Jay P Reddy et al. applied Santa Cruz Biotechnology Cdkn2a antibody to show the importance of protection of the ATM-mediated DDR-p53 signaling pathway for breast cancer prevention [ncbi , more ]. In 2009, Matthias Becker et al. used Santa Cruz Biotechnology Cdkn2a antibody to perform immunohistochemistry in order to reveal the importance of Bmi1 for tumor cell expansion [ncbi , more ]. In 2006, Patrice Delobel et al. applied Santa Cruz Biotechnology Cdkn2a antibody to detect p16 Ink4 expression patterns in brain and spinal cord of human P301S tau-transgenic mice and age-matched controls [ncbi , more ].
  • immunoprecipitationIn 2010, Pablo J Fernandez-Marcos et al. applied Santa Cruz Biotechnology Cdkn2a antibody to study the role of Sei1 in pancreatic beta-cells and the link between Sei1 and the core cell cycle regulators [ncbi , more ].
  • western blotIn 2010, Pablo J Fernandez-Marcos et al. applied Santa Cruz Biotechnology Cdkn2a antibody to study the role of Sei1 in pancreatic beta-cells and the link between Sei1 and the core cell cycle regulators [ncbi , more ]. Santa Cruz Biotechnology Cdkn2a antibody was employed in 2009 to perform western blot in order to show that the loss of Faf1 resulted in aberrant NF-kB signaling and tumor progression [ncbi , more ], to demonstrate that cold-inducible RNA-binding protein bypassed replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activation [ncbi , more ]and to perform western blot in order to show that the absence of p53 can result in tumourgenesis in those mesenchymal stem cells lacking p21 [ncbi , more ]. In 2008, Konstantinos J Mavrakis et al. employed Santa Cruz Biotechnology Cdkn2a antibody to detect p16 in mouse embryo fibroblasts (MEFs) [ncbi , more ]. Anna Sergeeva et al. applied Santa Cruz Biotechnology Cdkn2a antibody to perform western blot assays in order to investigate the molecular regulation mechanisms of Smad4 in the process of normal pancreas development and pancreatic ductal adenocarcinomas (PDAC) growth. (catalog: sc-1207) [ncbi , more ] in 2006 and Patrice Delobel et al. used Santa Cruz Biotechnology Cdkn2a antibody to detect p16 Ink4 expression patterns in brain and spinal cord of human P301S tau-transgenic mice and age-matched controls [ncbi , more ]. In 2005, Lakita G Cavin et al. applied Santa Cruz Biotechnology Cdkn2a antibody to detect p16 in mouse hepatocellular carcinoma cell lines 223 infected with adIKK-2 or adGFP (catalog: sc-1207) [ncbi , more ].
Novus BiologicalsNovus Biologicals Cdkn2a product
  • western blotIn 2001, C Tournier et al. applied Novus Biologicals Cdkn2a antibody to examine the role of MKK4 and MKK7 in the JNK signal transduction pathway [ncbi , more ].
AbcamAbcam Cdkn2a product
  • immunocytochemistryIn 2005, I Ching Wang et al. applied Abcam Cdkn2a antibody to study the function of forkhead box M1 to regulate the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase [ncbi , more ].
  • immunohistochemistryIn 2009, Matthias Becker et al. used Abcam Cdkn2a antibody to perform immunohistochemistry in order to reveal the importance of Bmi1 for tumor cell expansion [ncbi , more ].
  • western blotIn 2010, Tamihiro Kamata et al. employed Abcam Cdkn2a antibody to study the mechanism of Braf inactivation driving aneuploidy [ncbi , more ]. Abcam Cdkn2a antibody was used in 2009 to demonstrate that cold-inducible RNA-binding protein bypassed replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activation [ncbi , more ], to perform western blot in order to demonstrate that Puma imposes a significant, and Noxa a minor barrier to c-Myc-driven lymphomagenesis [ncbi , more ]and to perform western blot in order to show that the loss of Faf1 resulted in aberrant NF-kB signaling and tumor progression [ncbi , more ]. In 2006, Anna Sergeeva et al. utilized Abcam Cdkn2a antibody to perform western blot assays in order to investigate the molecular regulation mechanisms of Smad4 in the process of normal pancreas development and pancreatic ductal adenocarcinomas (PDAC) growth [ncbi , more ]. In 2005, Andrew V Samuelson et al. utilized Abcam Cdkn2a antibody to study that p400 is required for E1A to promote apoptosis [ncbi , more ].
Cell Signaling Technology
  • western blotChao Yung Wang et al. used Cell Signaling Technology Cdkn2a antibody to carry out western blot analysis in order to investigate the effect of obesity-induced long-term activation of Akt-mTOR signaling on vascular senescence and cardiovascular disease [ncbi , more ] in 2009 and Xin Zhang et al. used Cell Signaling Technology Cdkn2a antibody to perform western blot in order to study the regulation of NANOG in G1 to S transition in human embryonic stem cells [ncbi , more ].
ST CRZ BIOTECHNOOGY
  • immunohistochemistryIn 2010, Carmen Blanco-Aparicio et al. utilized Cdkn2a antibody to study the role of AKT in mammary tumorigenesis [ncbi , more ].
Articles Reviewed
  1. Tamihiro Kamata et al. (2010). "BRAF inactivation drives aneuploidy by deregulating CRAF".PMID 20978199
  2. Carmen Blanco-Aparicio et al. (2010). "Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models".PMID 20174572
  3. Jay P Reddy et al. (2010). "Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation".PMID 20133707
  4. Pablo J Fernandez-Marcos et al. (2010). "Normal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator sei1".PMID 20090907
  5. Rene Rodriguez et al. (2009). "Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells".PMID 19308294
  6. Chao Yung Wang et al. (2009). "Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR".PMID 19293429
  7. Deborah A Altomare et al. (2009). "Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice".PMID 19223589
  8. Ana Artero-Castro et al. (2009). "Cold-inducible RNA-binding protein bypasses replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activation".PMID 19158277
  9. Matthias Becker et al. (2009). "Polycomb group protein Bmi1 is required for growth of RAF driven non-small-cell lung cancer".PMID 19156217
  10. E M Michalak et al. (2009). "Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis".PMID 19148184
  11. Xin Zhang et al. (2009). "A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A".PMID 19139263
  12. Konstantinos J Mavrakis et al. (2008). "Tumorigenic activity and therapeutic inhibition of Rheb GTPase".PMID 18708578
  13. Anna Sergeeva et al. (2006). "Display technologies: application for the discovery of drug and gene delivery agents".PMID 17123658
  14. Patrice Delobel et al. (2006). "Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1".PMID 16507903
  15. I Ching Wang et al. (2005). "Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase".PMID 16314512
  16. Lakita G Cavin et al. (2005). "Transforming growth factor-alpha inhibits the intrinsic pathway of c-Myc-induced apoptosis through activation of nuclear factor-kappaB in murine hepatocellular carcinomas".PMID 16046551
  17. Andrew V Samuelson et al. (2005). "p400 is required for E1A to promote apoptosis".PMID 15741165
  18. C Tournier et al. (2001). "MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines".PMID 11390361