This is a review about p300, based on 49 published articles (read how Labome selects the articles), using p300 antibody in experiments. It is aimed to help Labome visitors find the most suited p300 antibody.
p300 synonym: KAT3B; RSTS2; p300; E1A-associated protein p300; E1A-binding protein, 300kD; histone acetyltransferase p300; p300 HAT

  • Santa Cruz CBP/p300 antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires. (catalog: sc-369) ncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology26p300 antibodysc-584, sc-585
    EMD Millipore8p300 antibody
    Abcam1p300 antibody
    BD Biosciences2
    Table 1. p300 antibody western blot.
  • Santa Cruz Biotechnology rabbit anti-p300 (C-20) polyclonal antibody (epitope mapping at the C-terminus of p300 of human origin) was used to study Ciglitazone induced cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells. (catalog: sc-585) ncbi, more
  • Santa Cruz anti-p300 was used in western blot to detect p300 levels in human HEK293T cells. (catalog: sc-585) ncbi, more
  • Santa Cruz Biotechnology anti-p300 antibody was used in western blot, immunoprecipitation, and immunohistochemistry to detect p300 in HeLa cells. (catalog: sc-585) ncbi, more
  • Santa Cruz Biotechnology polyclonal anti-p300 antibody was used in western blot to provide biochemical and genetic evidence to show that the HATs p300, CBP, and PCAF are regulators of E2A activity in B lymphocytes (catalog: sc-585) ncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal anti-p300 antibody was used in immunoprecipitation to study the Interaction of a novel zinc finger protein TReP-132 with CBP/p300 to regulate human CYP11A1 gene expression. (catalog: sc-584) ncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology9p300 antibodysc-584, sc-585
    EMD Millipore2p300 antibody
    Life Technologies Corporation1p300 antibody
    BD Biosciences1
    Table 2. p300 antibody immunoprecipitation.
  • Santa Cruz Biotechnology anti-p300 polyclonal antibody was used in western blot and immunoprecipitation to study the down-regulation of Msx1 promoter through recruiting histone deacetylase by Msx3 protein. (catalog: sc-584) ncbi, more
  • Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis.ncbi, more
  • Santa Cruz Biotechnology anti-p300 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs.ncbi, more
  • Santa Cruz Biotechnology anti-p300 antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathwayncbi, more
  • Santa Cruz Biotechnology anti-p300 antibody was used for ChIP assays in order to show that tumor suppressor PTEN can regulate ARE activation through chromatin modifications.ncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology8p300 antibodysc-369
    EMD Millipore3p300 antibody
    BD Biosciences1
    Table 3. p300 antibody ChIP assay.
  • Santa Cruz Biotechnology p300 antibody was used in western blot in order to study the role of SATB1-CtBP1 interaction in the repression and derepression of SATB1 target genes during Wnt signaling in T cellsncbi, more
  • Santa Cruz Biotechnology anti-p300 antibody was used in western blot in order to introduce Brd4 as a coactivator of NF-kappa B via specific binding to acetylated RelA.ncbi, more
  • Santa Cruz anti-p300 antibody was used to perform western blot in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters.ncbi, more
  • Santa Cruz p300 antibody was used in western blot in order to demonstrate that p300 plays a role in the activation of the MT-I genencbi, more
  • Santa Cruz Biotechnology p300 antibody was used in ChIP assays in order to study the molecular basis of CD4 regulation and provide a conceptual framework for understanding how the same regulatory elements can mediate both reversible and irreversible CD4 regulationncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology2p300 antibody
    EMD Millipore1p300 antibody
    Table 4. p300 antibody immunocytochemistry.
  • Santa Cruz anti-p300 antibody was used in ChIP assays in order to demonstrate that lithium suppresses Smad3/4-dependent TGF-beta-responsive gene transactivationncbi, more
  • Santa Cruz Biotechnology p300 antibody was used in western blot and immunoprecipitation to demonstrate that neural agrin-dependent reprogramming of myonuclei involves chromatin remodelling, histone hyperacetylation and histone hyperphosphorylation.ncbi, more
  • Santa Cruz Biotechnology E1A antibody was used in western blot to demonstrate that E4 ORF3 is critical to the replicative success of adenovirus during the IFN-induced antiviral state.ncbi, more
  • Santa Cruz Biotechnology p300 antibody was used in western blot to study the role of BRMS1 in the metastasis of breast cancer.ncbi, more
  • Santa Cruz Biotechnology rabbit anti-p300 (C-20) was used in western blot to demonstrate p300 modulating ATF4 stability and transcriptional activity independently of its acetyltransferase domain.ncbi, more
  • suppliernumreagent linkcited catalog
    EMD Millipore1p300 antibody05-257
    Santa Cruz Biotechnology1p300 antibodysc-585
    Table 5. p300 antibody immunohistochemistry.
  • Santa Cruz Biotechnology anti-p300 (C-20) was used in CHIP assay to determine whether Hic-5/ARA55 interacts with other coactivator proteins at glucocorticoid-responsive promoters in A1 2 cells derived from the T47D human mammary carcinoma cells linencbi, more
  • SCBT p300 (N-15) antibody was used in ChiP assay to investigate the regulation of ER alpha proteolysis and transcriptionncbi, more
  • SCBT p300 antibody (N-15) was used in ChIP assays to study aryl hydrocarbon receptor-mediated transcription in MCF-7 human breast carcinoma, T47D breast carcinoma cells, and HuH7 human liver carcinoma cells.ncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal p300 antibody was used in western blot to determine the mechanism underlying regulation of the insulin gene by Pdx-1.ncbi, more
  • Santa Cruz Biotechnology anti-p300 antibody was used in EMSA to study the regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology1p300 antibody
    Table 6. p300 antibody EMSA.
  • Santa Cruz Biotechnology anti-p300 antibody was used in western blot to detect p300 in TSA-treated MIA PaCa-2 cells.ncbi, more
  • Santa Cruz Biotechnology anti-p300 antibody was used in western blot, immunoprecipitation to study that notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1.ncbi, more
  • Santz mouse antihuman p300 antibody was used in chromatin immunoprecipitation (ChIP) to study the affect of ER transcription factor cross talk on a genome-wide scale in Breast Cancerncbi, more
  • Santa Cruz Biotechnology antibody against p300 (N-15) was used in chip assay to examine the dynamic association of coactivator p300 with the ERalpha-responsive promoters in human T47D cells.ncbi, more
  • Santa Cruz anti-p300 antibody was used in western blot and immunoprecipitation to study the acetylation of the human DNA glycosylase NEIL2 and inhibition of its activity.ncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal anti-human p300 antibody was used in western blot, immunoprecipitation, and ChIP assay to study p300 in RAW 264.7 cells with wt p300 or p300 HAT deletion mutant transfection.ncbi, more
  • Santa Cruz Biotechnology rabbit anti-p300 was used in western blot and immunocytochemistry to study that mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.ncbi, more
  • Santa Cruz Biotechnology p300 polyclonal antibody that does not cross-react with cAMP-response element-binding protein (CREB) binding protein (N-15) was used in western blot to study the function of the HMG-I/Y-related protein p8 to regulate the trans-activation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter by binding to p300 and Pax2 trans-activation domain-interacting protein (PTIP)ncbi, more
  • Santa Cruz Biotechnology anti-human p300 antibody was used in western blot to study the different function of protein kinase A and glycogen synthase kinase-3b for the activity of the exon 2-encoded transactivator domain of heterogeneous nuclear ribonucleoprotein D.ncbi, more
  • Santa Cruz Biotechnology goat anti-p300 antibody was used in western blot to study the role of deltex-1 as a transcriptional regulator downstream of the notch receptorncbi, more
  • Upstate mouse monoclonal anti-p300 (1:600) antibody was used in immunohistochemistry in order to demonstrate that Crx activates transcription by recruiting HAT-harboring co-activators to target gene promoters and promoting histone acetylation. (catalog: 05-257) ncbi, more
  • Upstate Biotechnology anti-p300 antibody was used in western blot and immunoprecipitation to detect p300 in HeLa cells.ncbi, more
  • Millipore anti-p300 was used to perform western blot in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis.ncbi, more
  • Upstate anti-p300 antibody was used in western blot to study the effect of EGF receptor signaling on aryl hydrocarbon receptor-mediated transcription and cell differentiation in human epidermal keratinocytesncbi, more
  • Upstate anti-p300 antibody was used to perform ChIP assays in order to study the functions of protein arginine methyltransferase 1. ncbi, more
  • Upstate anti-p300 antibody was used to perform ChIP assays in order to sthudy the function of coiled-coil coactivator's N-terminal in regulating transcriptional activation.ncbi, more
  • Oncogene anti-p300 was used in western blot to study a role for STAG/Scc3 in transcriptional regulation by cohesins.ncbi, more
  • Oncogene Research anti-E1A monoclonal antibody was used in western blot to study the DNA damage response and MCL-1 destruction initiating apoptosis in adenovirus-infected cells.ncbi, more
  • Upstate Biotechnology anti-p300 antibody was used in western blot to study the molecular basis of p53 functional inactivation by the leukemic protein MLL-ELLncbi, more
  • Upstate Biotechnology E1a antibody was used in western blot, immunoprecipitation, and ChIP assay to study the regulation of the FGF-4 gene.ncbi, more
  • Upstate Biotechnology anti-p300 antibody was used in western blot to study the different function of protein kinase A and glycogen synthase kinase-3b for the activity of the exon 2-encoded transactivator domain of heterogeneous nuclear ribonucleoprotein D.ncbi, more
  • Calbiochem monoclonal anti-p300 antibody was used in human Calu-6 cells and in immunocytochemistry to study the function of ZNF265.ncbi, more
Life Technologies CorporationLife Technologies Corporation p300 product
  • Zymed Laboratories anti-p300 monoclonal antibody was used in immunoprecipitation to study transforming growth factor-beta signalingncbi, more
  • Abcam anti-p300 antibody was used to carry out western blot analysis in order to determine the histone H3 lysine 56 acetylation by histone acetyl transferases CBP/p300.ncbi, more
BD Biosciences
  • BD Biosciences mouse anti-human p300 antibody was used in ChIP assays in order to study the role of the alternative expression from AE2 gene in the physiology and pathophysiology of the hepatobiliary tractncbi, more
  • Pharmingen anti-p300 monoclonal antibody (NM11) was used in western blot and immunoprecipitation to study the effects of MAPK signaling on the activity of hypoxia-inducible factors by promoting the formation of the HIF-p300/CBP complex and by modulating the transactivation activity of p300/CBPncbi, more
Articles Reviewed
  1. Lan Wang et al. (2011). "The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation".PMID 21764752
  2. Di Feng et al. (2010). "Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression".PMID 20935208
  3. Yang Yang et al. (2009). "Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment".PMID 19308286
  4. Chandrima Das et al. (2009). "CBP/p300-mediated acetylation of histone H3 on lysine 56".PMID 19270680
  5. Carrie Hayes Sutter et al. (2009). "EGF receptor signaling blocks aryl hydrocarbon receptor-mediated transcription and cell differentiation in human epidermal keratinocytes".PMID 19255421
  6. Kensuke Sakamoto et al. (2009). "Role of the tumor suppressor PTEN in antioxidant responsive element-mediated transcription and associated histone modifications".PMID 19158375
  7. Prabhat Kumar Purbey et al. (2009). "Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1".PMID 19103759
  8. Bo Huang et al. (2009). "Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA".PMID 19103749
  9. Hiroki Matsuda et al. (2009). "Novel functions of protein arginine methyltransferase 1 in thyroid hormone receptor-mediated transcription and in the regulation of metamorphic rate in Xenopus laevis".PMID 19047371
  10. Susan Nozell et al. (2008). "The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes".PMID 18779315
  11. Yong Li et al. (2008). "Zinc-induced formation of a coactivator complex containing the zinc-sensing transcription factor MTF-1, p300/CBP, and Sp1".PMID 18458062
  12. Ming Yu et al. (2008). "Nucleoprotein structure of the CD4 locus: implications for the mechanisms underlying CD4 regulation during T cell development".PMID 18322012
  13. Fabián Arenas et al. (2008). "Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells".PMID 18188457
  14. Min Huei Liang et al. (2008). "Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling".PMID 18077182
  15. Guang Hua Peng et al. (2007). "Crx activates opsin transcription by recruiting HAT-containing co-activators and promoting histone acetylation".PMID 17656371
  16. Aymeric Ravel-Chapuis et al. (2007). "Postsynaptic chromatin is under neural control at the neuromuscular junction".PMID 17304221
  17. Amanda J Ullman et al. (2007). "Adenovirus E4 ORF3 protein inhibits the interferon-mediated antiviral response".PMID 17301128
  18. Sergey Denissov et al. (2007). "Identification of novel functional TBP-binding sites and general factor repertoires".PMID 17268553
  19. Yuan Liu et al. (2006). "Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis".PMID 17000776
  20. Catherine K Yang et al. (2006). "Role of the N-terminal activation domain of the coiled-coil coactivator in mediating transcriptional activation by beta-catenin".PMID 16931570
  21. Irina Lassot et al. (2005). "p300 modulates ATF4 stability and transcriptional activity independently of its acetyltransferase domain".PMID 16219772
  22. M D Heitzer et al. (2006). "Mechanism of action of Hic-5/androgen receptor activator 55, a LIM domain-containing nuclear receptor coactivator".PMID 16141357
  23. Christopher C Valley et al. (2005). "Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus".PMID 15964799
  24. Jason Matthews et al. (2005). "Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters".PMID 15964790
  25. Tessy Iype et al. (2005). "Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes".PMID 15743769
  26. Shunbin Ning et al. (2005). "Regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling".PMID 15664995
  27. Weiqi Huang et al. (2005). "Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex".PMID 15647279
  28. Fei Chen et al. (2005). "Ciglitazone induces early cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells through p65 phosphorylation".PMID 15618021
  29. Eri Ishiko et al. (2005). "Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1".PMID 15563463
  30. David G DeNardo et al. (2005). "Global gene expression analysis of estrogen receptor transcription factor cross talk in breast cancer: identification of estrogen-induced/activator protein-1-dependent genes".PMID 15514030
  31. Sarah E Aiyar et al. (2004). "Attenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor".PMID 15342491
  32. Kishor K Bhakat et al. (2004). "Acetylation of the human DNA glycosylase NEIL2 and inhibition of its activity".PMID 15175427
  33. Maria Carla Motta et al. (2004). "Mammalian SIRT1 represses forkhead transcription factors".PMID 14980222
  34. Wu Guo Deng et al. (2003). "Regulation of inducible nitric oxide synthase expression by p300 and p50 acetylation".PMID 14662860
  35. Enrique Lara-Pezzi et al. (2004). "Evidence of a transcriptional co-activator function of cohesin STAG/SA/Scc3".PMID 14660624
  36. Andrea Cuconati et al. (2003). "DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells".PMID 14633975
  37. Rui Hong et al. (2003). "The human proliferating Cell nuclear antigen regulates transcriptional coactivator p300 activity and promotes transcriptional repression".PMID 12937166
  38. Kiyoshi Higashi et al. (2003). "Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3".PMID 12917425
  39. Dmitri Wiederschain et al. (2003). "Molecular basis of p53 functional inactivation by the leukemic protein MLL-ELL".PMID 12773566
  40. Nianli Sang et al. (2003). "MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300".PMID 12588875
  41. Tamara Nowling et al. (2003). "The co-activator p300 associates physically with and can mediate the action of the distal enhancer of the FGF-4 gene".PMID 12488456
  42. Curtis Bradney et al. (2003). "Regulation of E2A activities by histone acetyltransferases in B lymphocyte development".PMID 12435739
  43. Christy J Fryer et al. (2002). "Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex".PMID 12050117
  44. Albrecht Hoffmeister et al. (2002). "The HMG-I/Y-related protein p8 binds to p300 and Pax2 trans-activation domain-interacting protein to regulate the trans-activation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter".PMID 11940591
  45. Mate Tolnay et al. (2002). "Protein kinase A enhances, whereas glycogen synthase kinase-3 beta inhibits, the activity of the exon 2-encoded transactivator domain of heterogeneous nuclear ribonucleoprotein D in a hierarchical fashion".PMID 11903055
  46. N Yamamoto et al. (2001). "Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor".PMID 11564735
  47. D J Adams et al. (2001). "ZNF265--a novel spliceosomal protein able to induce alternative splicing".PMID 11448987
  48. F Gizard et al. (2001). "A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression".PMID 11349124
  49. R Mehra-Chaudhary et al. (2001). "Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter".PMID 11115394