This is a review about p27, based on 108 published articles (read how Labome selects the articles), using p27 antibody in experiments. It is aimed to help Labome visitors find the most suited p27 antibody.
p27 synonym: CDKN4; KIP1; MEN1B; MEN4; P27KIP1; cyclin-dependent kinase inhibitor 1B

Santa Cruz BiotechnologySanta Cruz Biotechnology p27 product
  • Santa Cruz anti-p27 was used in 1:1000 dilution to perform western blot in order to show that CSN plays an important role for cell autophagy in K562 cells.ncbi, more , figure 1
  • Figure 1
    p27 antibody western blot Santa Cruz Biotechnology
    p27 antibody western blot Santa Cruz Biotechnology
    The level of Cul1 neddylation (top panels, indicates neddylated Cul-1), Skp2 protein (second panels) and p27 protein (third panels) was determined in n = 3 shCSN2 (left) and shCSN5 (right) samples by western blot.
    Claire Pearce et al. (2009). "Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy".PMID 19400951
  • Santa Cruz anti-p27Kip1 and anti-phospho-p27Kip1 was used to perform western blot in order to show the role of cyclin K and cyclin D1b in multiple myeloma. (catalog: sc-528,sc-9104) ncbi, more
  • Santa Cruz Biotechnology p27 antibody (1:100) was used in western blot to study the role of an unliganded TRbeta mutant in pituitary tumorigenesis in vivo. (catalog: sc-1641) ncbi, more
  • Santa Cruz Biotechnology p27Kip1 antibody was used in western blot to demonstrate that pituitary adenylate cyclase activating polypeptide anti-mitogenic signaling in cerebral cortical progenitors is regulated by p57Kip2-dependent CDK2 activity. (catalog: SC-528) ncbi, more
  • Santa Cruz Biotechnology rabbit anti-p27 antibody (1/2,000) was used for western blot in order to investigate the role of ILK in the regulation of human intestinal cells migration and proliferation.ncbi, more
  • Santa Cruz Biotechnology p27Kip1 antibody was used for immunoprecipitation in order to show that cyclin D1 is essential for estrogen regulation of cyclin E2.ncbi, more
  • Santa Cruz Biotechnology p27kip1 was used for western blot in order to dentify miR-181a as a regulator of p27 mRNA translation during myeloid cell differentiation.ncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology46p27 antibodysc-1641, SC-528, sc-528,sc-9104
    EMD Millipore4p27 antibody
    Life Technologies Corporation3p27 antibody
    Thermo Scientific Pierce Products1p27 antibody
    BD Biosciences32
    Cell Signaling Technology3p27 antibody
    Sigma-Aldrich1
    Dako2p27 antibody
    New England Biolabs1
    Individual Researcher1
    Table 1. p27 antibody western blot.
  • Santa Cruz Biotechnology rabbit anti-p27Kip1 antibody (1:50) was used to perform immunofluorescence in order to study the KIS opposed stathmin-mediating VSMC migration.ncbi, more
  • Santa Cruz Biotechnology anti-p27 antibody was used in western blot in order to study the reguation of the expression of Ect2, MgcRacGAP, and MKLP1 during cell cycle progressionncbi, more
  • Santa Cruz Biotechnology anti-p27 antibody was used to carry out western blot analysis in order to investigate whether FGFR4 plays a role in promoting the progression of hepatocellular carcinoma.ncbi, more
  • Santa Cruz anti-p27Kip1 was used to perform western blot in order to show that PTEN-null tumors is promoted to autophagy and more sensitive to lysosomotropic agents after Akt inhibition.ncbi, more
  • Santa Cruz Biotechnology p27 antibody was used in western blot in order to study the role of Cdh1/APC in tumorigenesisncbi, more
  • suppliernumreagent link
    Thermo Scientific Pierce Products4p27 antibody
    Santa Cruz Biotechnology3p27 antibody
    EMD Millipore2p27 antibody
    Life Technologies Corporation2p27 antibody
    BD Biosciences5
    Sigma-Aldrich1
    Dako2p27 antibody
    MBL International1
    Leica Microsystems2
    Table 2. p27 antibody immunohistochemistry.
  • Santa Cruz Biotechnology mouse monoclonal p27 antibody was used in western blot in order to examine the effects of combining a proteasome inhibitor with an HDAC inhibitor in GBM cell linesncbi, more
  • Santa Cruz Biotechnology anti-p27kip1 antibody was used to perform western blot in order to study how genistein regulate tumor suppressor genes in prostate cancer cells.ncbi, more
  • Santa Cruz Biotechnology anti-p27Kip1 antibody was used in western blot to elucidate the anti-mitogenic effect of a proteasome inhibitor in relation to BMP signalling in colon cancer.ncbi, more
  • Santa Cruz Biotechnology anti-p27Kip1 was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis.ncbi, more
  • Santa Cruz Biotechnology anti-p27/kip1 antibody was used in western blot in order to demonstrate that sulindac suppresses beta-catenin expression in human cancer cellsncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology6p27 antibody
    BD Biosciences4
    Table 3. p27 antibody immunoprecipitation.
  • Santa Cruz Biotechnology p27 antibody was used in western blot to investigate the role of these complexes in the biology of mesenchymal stem cells (MSCs).ncbi, more
  • Santacruz Biotechnology anti-p27 antibody was used in human cells and in western blot, immunocytochemistry to study the role for p21cip/waf1 and p27kip1 in TNF-alpha-induced inhibition of proliferation in human glioma cells.ncbi, more
  • Santa Cruz Biotechnology p27Kip1 antibody was used in western blot to study the role of PDCD4 in retinoic acid-induced terminal granulocytic differentiation of human myeloid leukemia cells.ncbi, more
  • Santa Cruz p27Kip1 antibody was used in immunohistochemistry to demonstrate the homeodomain transcription factor Phox2a coordinates cell cycle exit and differentiation by inducing p27 (Kip1) transcription.ncbi, more
  • Santa Cruz Biotechnology p27 antibody was used in western blot to explore the relationship between IGFBP-3 and androgens.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology4p27 antibody
    BD Biosciences5
    Table 4. p27 antibody immunocytochemistry.
  • Santa Cruz Biotech anti-p27 antibody (C-19) was used in human cells and in western blot to study the mechanism that regulates E7 expression in differentiated cells.ncbi, more
  • Santa Cruz Biotechnology p27 antibody was used in western blot to demonstrate that combination of Ad-mda7 with Herceptin may be a novel therapy for breast cancer.ncbi, more
  • Santa Cruz Biotechnology polyclonal anti-p27 antibody was used in human cells and in western blot to study the role for physical association between Cul4A, DDB1, and Skp2 and the COP9 signalosome in proteolysis of p27Kip1.ncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal p27 antibody was used in western blot and immunocytochemistry to detect p27 expression in the human metastatic melanoma cell line HO-1ncbi, more
  • SCBT p27 antibody was used in western blot to investigate the repression of RNA polymerase I transcription by PTEN.ncbi, more
  • Santa Cruz Biotechnology anti-p27 antibody was used in western blot to study the role for dynamin-2 in VEGFR-2/KDR-mediated endothelial signaling in human umbilical vein endothelial cells (HUVECs).ncbi, more
  • SCBT anti-p27 (C-19) antibody was used in western blot to investigate the role of ORC2 in CDK2 activationncbi, more
  • Santa Cruz Biotechnology antibody against p27Kip1 (product C-19) was used in immunoprecipitation to isolate p27Kip1 and in western blot to detect p27Kip1 in human primary effusion lymphoma (PEL) cell lines BC2 and BC3ncbi, more
  • Santa Cruz p27 antibody was used in western blot to study prognostic and diagnostic implications of cell cycle-regulated proteins pRB2/p130, p107, E2F4, p27, and pCNA.ncbi, more
  • Santa Cruz Biotechnology anti-p27 antibody was used in western blot to demonstrate that mutation of Cys105 inhibits dimerization of p12CDK2-AP1.ncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal p27Kip1 (C-19) antibody was used in western blot to study retinoblastoma phosphorylation in neuronal cell deathncbi, more
  • Santa Cruz Biotech anti- p27KIP1 antibody was used in western blot to study the suppression of cyclic GMP-specific phosphodiesterase 5 promoting apoptosis and inhibiting growth in HT29 cells.ncbi, more
  • Santa Cruz Biotechnology anti-p27 antibody (F8) was used in western blot to study GCP in vitro and in vivo for potential utility as a prostate cancer chemopreventative agent in human prostate cancer cell line.ncbi, more
  • Santa Cruz Biothechnology anti-p27Kip1 antibody F-8 was used in western blot to study the activity of the p53-independent DNA damage G2 checkpoint which is modulated by activation of Ras-Ral pathway.ncbi, more
  • Santa Cruz Biotechnology anti-p27 antibody (sc-776) was used in human MCF7 cells and in western blot to study the effect of DRF 3188 on the cell cycle of MCF 7 breast cancer cells.ncbi, more
  • Santa Cruz Biotechnology anti-p27kip1 (C-19) monoclonal antibody was used in western blot to study the role of shox in cell cycle, apoptosis, and human growth plate chondrocytes.ncbi, more
  • Santa Cruz polyclonal anti-p27kip1 antibody (1:1000) was used in western blot to study the interaction of Nkx3.1 and p27kip1 in prostate tumor initiation.ncbi, more
  • Santa Cruz Biotechnology p27kip1 antibody was used in western blot to study the role of PTEN in PDGF-induced DNA synthesis.ncbi, more
  • Santa Cruz Biotechnology p27Kip1 antibody was used in western blot to study the role of AMF/PGI in the regulation of cell proliferation.ncbi, more
  • Santa Cruz anti-p27Kip1 antibody was used in western blot to study the association of p55 with Rb.ncbi, more
  • Santa Cruz Biotechnology anti-p27 antibody (C-19) was used in human MCF-7 cells and in immunoprecipitation, western blot to study the role for the interaction of p27Kip1 with CRM1/Ran in a nuclear export signal and the linking p27 export and proteolysis.ncbi, more
  • Santa Cruz Biotechnology anti-human p27 antibody was used in HEK293F cells and in immunoprecipitation, western blot to study the role of association of TSG101 with p21Cip1/WAF1 in regulating of cell growth and differentiation.ncbi, more
  • Santa Cruz Biotechnology polyclonal antibody against p27 (C-19) was used in immunoprecipitation and immunocytochemistry to study the different p27Kip1 phosphorylation patterns during cell cycle progression in human epithelial cells resistant to transforming growth factor beta-mediated G1 arrest.ncbi, more
  • Santa Cruz Biotechnology anti-p27 antibody (C-19) was used in human cells and in immunocytochemistry to study the effects of SF/HGF, c-myc, p27, Cdk2, or E2F1 on glioblastoma cell cycle progression.ncbi, more
  • Santa Cruz anti-human p27 antibody was used in western blot to study the role for LATS1 tumor suppressor in regulating G2/M transition and apoptosis in human cells.ncbi, more
  • Santa Cruz anti-p27 antibody was used in human thyroid carcinoma cells and in immunoprecipitation to study the role for vitamin D in arresting thyroid carcinoma cell growth and inducing p27 dephosphorylation and accumulation.ncbi, more
  • Santa Cruz Biotechnology p27 kip1 antibody was used in western blot to study the effects of the natural plasma constituent recovered from type 2 diabetic patients (dm-LDL) on endothelial cells.ncbi, more
  • Santa Cruz Biotechnology p27Kip1 antibody was used in western blot to stduy the mechanism (s) by which Cdk4 activity is regulated in MCF-7 cells.ncbi, more
  • Santa Cruz Biotechnology anti-p27KIP1 antibody was used in western blot to study the requirement of galectin-3 phosphorylation for its anti-apoptotic function and cell cycle Aarrest.ncbi, more
  • Santa Cruz Biotechnology murine polyclonal anti-p27kip1 antibody was used in sections from Wistar rats arteries and rat aortic embryonal SMCs (A10 cells), which were used in immunohistochemistry and western blot, to study the effect of membrane-bound protein kinase A on smooth muscle cell proliferation in vitro and in vivo.ncbi, more
  • Calbiochem/Oncogene Science mouse monoclonal anti-p27Kip1 (clone DCS72; Ab-2) was used in immunohistochemistry to detect p27Kip1 immunoreactivity in human bladder cancer.ncbi, more
  • Upstate Biotechnology polyclonal rabbit anti-p27 antibody was used in western blot to investigate basal and Vitamin D-regulated expression and activity of the synthesizing (CYP27B1) and metabolizing (CYP24A1) hydroxylase.ncbi, more
  • Chemicon p27Kip1 antibody was used in immunohistochemistry to demonstrate the homeodomain transcription factor Phox2a coordinates cell cycle exit and differentiation by inducing p27 (Kip1) transcription.ncbi, more
  • Oncogene Research Products p27Kip-1 antibody was used in western blot at dilutions of 1:500 to 1:1000 to facilitate the establishment of an in vitro model that can be reliably used to study the pathogenesis of MCL.ncbi, more
  • Upstate Biotechnology anti-p27kip1 antibody was used in human breast cancer cells and in western blot to study the role for Q227L-Galpha in inhibiting growth of established tumors of later-stage human breast cancer cells in athymic mice.ncbi, more
  • Oncogene Research Products anti-p27 antibody was used in western blot to study the effects of over-expression of the potential tumor suppressor gene IGFBP-rP1/mac25 on cell-cycle kinetics in human prostate cancer cells.ncbi, more
Life Technologies CorporationLife Technologies Corporation p27 product
  • ZYMED anti-p27 antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway.ncbi, more
  • Zymed rabbit polyclonal antibody directed against p27Kip1 was used in western blot and immunohistochemistry to examine the role of Cks1 expression in breast cancer and its relation to p27Kip1 and Skp2 expression and to tumor aggressiveness.ncbi, more
  • Zymed monoclonal mouse anti-p27kip1 antibody was used in immunohistochemistry to study the role for altered expression of Skp2, c-Myc, and p27 proteins in chronic gastritis in paraffin sections from patients with chronic gastritis.ncbi, more
  • Zymed anti-pThr187-p27 antibody was used in human thyroid carcinoma cells and in western blot to study the role for vitamin D in arresting thyroid carcinoma cell growth and inducing p27 dephosphorylation and accumulation.ncbi, more
Thermo Scientific Pierce ProductsThermo Scientific Pierce Products p27 product
  • Lab Vision mouse monoclonal anti-p27 antibody (1:50) was used in immunohistochemistry in order to investigate the expression of p16INK4a, p21WAF1/CIP1, p27KIP1, and p53 in human corneal endothelial cell (HCEC) senescence ex vivo at various donor agesncbi, more
  • NeoMarkers p27 antibody was used in immunohistochemistry to study the role of notch signaling in hair cell increases and cell differentiation in COUP-TFI-/- mice.ncbi, more
  • Neomarkers anti-p27 Kip1 antibody was used in western blot to study the function of the mitogen-activated protein kinase kinase kinase DLK as a key regulator of keratinocyte terminal differentiationncbi, more
  • Neomarkers anti-p27Kip1 antibody was used in immunohistochemistry to study the role of Cx32/GJIC in radiation-induced tumorigenesis of the liver.ncbi, more
  • Neomarkers mouse monoclonal anti-p27kip1 antibody (clone DCS-72.F6) was used in immunohistochemistry to study the expression of cell-cycle-regulated proteins pRb2/p130, p107, p27kip1, p53, mdm-2, and Ki-67 in prostatic gland adenocarcinoma in paraffin sections from human tumor.ncbi, more
Cell Signaling TechnologyCell Signaling Technology p27 product
  • Cell Signaling Technology anti-p27KIP antibody was used in western blot to study the function of the 19 S proteasomal subunit POH1 in the regulation of c-Jun ubiquitination, stability, and subcellular localization in human HEK293 cells.ncbi, more
  • Cell Signaling anti-p27 antibody was used in western blot to detect p27 in HT-29 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.ncbi, more
  • Cell Singaling Technology anti-phospho-JNK antibody was used in western blot to study the function of the mitogen-activated protein kinase kinase kinase DLK as a key regulator of keratinocyte terminal differentiationncbi, more
Sigma-Aldrich
  • Sigma-Aldrich anti-p27 Kip1 (DCS-72) was used in western blot to detect p27 Kip1 expression levels in spinal cord and brain of human P301S tau-transgenic mice and age-matched controls, and in immunohistochemistry to investigate p27 Kip1 expression patterns in spinal cord (Sc), brainstem (BS), and cerebral cortex (Cx) of human P301S tau-transgenic (Tg) mice and age-matched controls, as well as in the frontal cortex from a human case of FTDP-17 with the P301L tau mutation.ncbi, more
BD Biosciences
  • BD Pharmingen anti-p27CDKN1B antibody was used to perform western blot in order to show that p53-dependent cell proliferation and survival could be regulated by atg7.ncbi, more
  • BD Transduction Laboratories anti-p27 antibody was used in western blot in order to elucidate the essential role of lamin A/C phosphorylated by EBV-PK (Epstein-Barr virus (EBV) encoded viral protein kinase) during lytic viral replication.ncbi, more
  • BD Transduction Laboratories p27Kip1 antibody was used for western blot in order to show that cyclin D1 is essential for estrogen regulation of cyclin E2.ncbi, more
  • BD mouse anti-p27 antibody (catalog no:610241) was used in western blot to combine computational simulations, experimental testing of simulation results, and finally reverse engineering of a protein interaction network to define potential therapeutic strategies for de novo trastuzumab resistant breast cancerncbi, more
  • BD Biosciences mouse anti-p27Kip1 antibody (1:1,000) was used to perform western blot in order to study the KIS opposed stathmin-mediating VSMC migration.ncbi, more
  • BD Biosciences p27 antibody was used in western blot and immunoprecipitation in order to study the role of Jab1 in mediating EGFR signalingncbi, more
  • BD Biosciences anti-p27Kip1 was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis.ncbi, more
  • BD Transduction Laboratories mouse monoclonal anti-p27/Kip1 antibody (1:200) was used in immunohistochemistry to study the expression and function of a putative Notch target gene.ncbi, more
  • BD Transduction Laboratories p27kip1 antibody was used in immunohistochemistry in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic modelsncbi, more
  • BD Biosciences monoclonal anti-p27 antibody was used in western blot to study the mechanism through which availability of substrate recognition subunits and substrates can regulate the ubiquitin ligase activity.ncbi, more
  • BD-Transduction Laboratories monoclonal anti-p27 antibody (K25020) was used in human (T98G, IMR-90) cells and in western blot, immunoprecipitation to study the role for cyclins and CDK "inhibitors" in Thr172 phosphorylation of CDK4.ncbi, more
  • BD Transduction Laboratory monoclonal anti-p27 antibody was used in human cells and in immunocytochemistry to study the role for physical association between Cul4A, DDB1, and Skp2 and the COP9 signalosome in proteolysis of p27Kip1.ncbi, more
  • BD Biosciences mouse anti-Kip1/p27 antibody was used in western blot and immunocytochemistry to study the function of forkhead box M1 to regulate the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase.ncbi, more
  • Transduction Laboratories Kip1/p27 antibody was used in western blot to investigate the regulation of Cdc6 protein stability by p53.ncbi, more
  • BD Transduction Laboratories p27kip1 antibody was used in western blot to study interleukin 7 effects on T cell acute lymphoblastic leukemia cellsncbi, more
  • Transduction Laboratories anti-Kip1/p27 antibody was used in western blot to detect Kip1/p27 in NIH 3T3 cells transiently transfected with vector, RACK1, or mutant RACK1.ncbi, more
  • Transduction Laboratories p27 (K25020) antibody was used in western blot to study the efffect of Cdt1 phosphorylation by cyclin A-dependent kinasesncbi, more
  • Transduction laboratories anti-p27kip was used in western blot to detect p27 in human HEK293T cells.ncbi, more
  • BD Biosciences anti-p27 was used in western blot to detect p27 in the lysates of human WI-38 fibroblastsncbi, more
  • Transduction Laboratories p27Kip1 antibody (1:2, 500) was used in western blot to study the role of Sp1 family in the overexpression of p27 (Kip1).ncbi, more
  • Transduction Laboratories monoclonal anti-p27 antibody was used in human HEK293 cells and in western blot to study the role for the p27Kip1 inhibition of GRB2-SOS formation in regulating Ras activation.ncbi, more
  • Transduction Laboratories mouse p27KIP1 antibody (clone 57) was used in immunohistochemistry to study the PTEN and p27 expression level during tumor cell proliferationncbi, more
  • BD Biosciences anti-p27 antibody was used in western blot to study that resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells.ncbi, more
  • BD Biosciences PharMingen polyclonal p27 antibody was used in western blot and immunohistochemistry to assesse p27 and JAB1 in systemic anaplastic large cell lymphoma (ALCL).ncbi, more
  • BD Transduction Laboratories mouse monoclonal anti-p27 antibody was used in human MCF-7 cells and in immunocytochemistry to study the role for the interaction of p27Kip1 with CRM1/Ran in a nuclear export signal and the linking p27 export and proteolysis.ncbi, more
  • BD Biosciences antibody against p27/Kip1 was used in western blot to identify a member of forkhead transcription factor FKHRL1 as a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells.ncbi, more
  • Transduction Laboratories against Kip1 (p27) antibody was used in western blot to study the expression of Kip1 (p27) in the Eker renal tumors.ncbi, more
  • Transduction Laboratories anti-p27Kip1 antibody K25020 was used in MCF-7S human breast cancer cells and in immunoprecipitation, western blot to study the mechanism by which IGF-I induces the activation of the cyclin D1-CDK4 complex.ncbi, more
  • Transduction Laboratories monoclonal antibody against p27 was used in western blot and immunocytochemistry to study the different p27Kip1 phosphorylation patterns during cell cycle progression in human epithelial cells resistant to transforming growth factor beta-mediated G1 arrest.ncbi, more
  • PharMingen anti-p27Kip1 (13231A) was used in western blot to identify cyclin E as a target of WT1 transcriptional repression.ncbi, more
  • Transduction Laboratories anti-Kip1p27 antibody was used in human cells and in western blot to study the effects of SF/HGF, c-myc, p27, Cdk2, or E2F1 on glioblastoma cell cycle progression.ncbi, more
  • Transduction Laboratories monoclonal anti-p27 antibody was used in human thyroid carcinoma cells and in immunocytochemistry, immunoprecipitation, western blot to study the role for vitamin D in arresting thyroid carcinoma cell growth and inducing p27 dephosphorylation and accumulation.ncbi, more
  • Transduction Laboratories antibody to p27 was used in western blot to examine p27 levels in HT29 colon carcinoma sublines U9, HP1, HD3, and HD4.ncbi, more
  • Transduction Laboratories p27KIP1 antibody was used in western blot to study the induction of the BCL-6 transcriptional repressor by forkhead transcription factor AFXncbi, more
  • Transduction Laboratories p27kip1 antibody was used in western blot to study the effect of CCI-779 on the proliferation of a panel of breast cancer cell lines.ncbi, more
  • PharMingen mouse monoclonal p27kip1 antibody was used in western blot to study the relationship between UCN-01 actions and activity of the MAPK pathway.ncbi, more
  • Transduction Laboratories monoclonal anti-p27 antibody was used in paraffin sections from human tumors and in immunohistochemistry to study the correlation between PTEN and Akt, p27, cyclin D1 in primary epithelial ovarian carcinomas.ncbi, more
  • Transduction Laboratories polyclonal anti-human p27 antibody was used in western blot to study interaction of human thymidine kinase 1 with p21Waf1.ncbi, more
  • Dako anti-p27kip1 antibody was used to perform immunohistochemistry in order to study the features of the potential molecular oncogenic mechanism of CDK6-BLPDs.ncbi, more
  • DakoCytomation monoclonal mouse anti-human p27 antibody was used in human breast cancer cell lines MCF-7 and in western blot to study the role for p27 in the development of resistance to docetaxel in breast cancer cells.ncbi, more
  • DAKO monoclonal anti-p27 antibody (clone SX53G8) was used in immunohistochemistry to study the level of expression and correlation of p27 and Jab1 in various melanocytic lesions, and to identify their potential significance for diagnosis and prognosis of such lesions in sections from human.ncbi, more
  • Dako monoclonal p27Kip1 antibody (1:1000) was used in western blot to evaluate expression levels of Jun activation domain-binding protein 1 (JAB1) in breast cancer tissue and adjacent normal tissue.ncbi, more
MBL International
  • Medical and Biological Laboratories anti-p27 antibody was used in immunohistochemistry to study the role for targeting the cytoskeleton in inhibition of metastatic outgrowth from single dormant tumor cells.ncbi, more
ONCOGENE LABORATORIES
  • Oncogene Laboratories mouse anti-p27 monoclonal antibody was used in western blot and immunocytochemistry to detect p27 in the human PEL cell line BCBL1ncbi, more
Leica Microsystems
  • Novocastra Laboratories mouse monoclonal anti-p27KIP1 antibody (clone 1B4) was used in immunohistochemistry to study nuclear localization of KLF4 in early-stage breast cancer.ncbi, more
  • Novocastra mouse monoclonal anti-p27KIP1 antibody (clone 1B4) was used in immunohistochemistry to study GnT-V expression in non-small cell lung cancers.ncbi, more
New England Biolabs
  • New England Biolabs polyclonal anti-p27 antibody was used in western blot to study that disialoganglioside (GD3) synthase gene expression suppresses vascular smooth muscle cell responses via the inhibition of ERK1/2 phosphorylation, cell cycle progression, and matrix metalloproteinase-9 expression.ncbi, more
Individual Researcher
  • Dr.Samuel H. Speck (Emory University School of Medicine) rabbit polyclonal anti-v-cyclin antibody was used in western blot to determine the contribution of v-cyclin-mediated cell cycle regulation to the viral life cycle.ncbi, more
Articles Reviewed
  1. In Hye Lee et al. (2012). "Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress".PMID 22499945
  2. Jixin Cui et al. (2010). "Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family".PMID 20688984
  3. Veronique Marsaud et al. (2010). "Cyclin K and cyclin D1b are oncogenic in myeloma cells".PMID 20459741
  4. Qiao Meng et al. (2010). "Simian virus 40 T/t antigens and lamin A/C small interfering RNA rescue the phenotype of an Epstein-Barr virus protein kinase (BGLF4) mutant".PMID 20147387
  5. David Gagné et al. (2010). "Integrin-linked kinase regulates migration and proliferation of human intestinal cells under a fibronectin-dependent mechanism".PMID 19885839
  6. C Elizabeth Caldon et al. (2009). "Estrogen regulation of cyclin E2 requires cyclin D1 but not c-Myc".PMID 19564413
  7. Claire Pearce et al. (2009). "Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy".PMID 19400951
  8. Rafael Cuesta et al. (2009). "miR-181a regulates cap-dependent translation of p27(kip1) mRNA in myeloid cells".PMID 19273599
  9. Dong Chen et al. (2009). "Clinicopathologic features of CDK6 translocation-associated B-cell lymphoproliferative disorders".PMID 19145199
  10. Ozgur Sahin et al. (2009). "Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance".PMID 19118495
  11. Thomas H Langenickel et al. (2008). "KIS protects against adverse vascular remodeling by opposing stathmin-mediated VSMC migration in mice".PMID 19033656
  12. Laetitia Seguin et al. (2009). "CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase".PMID 19015243
  13. Xinqiang Huang et al. (2009). "Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis".PMID 19009564
  14. Michael Degtyarev et al. (2008). "Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents".PMID 18838554
  15. Dalit Barkan et al. (2008). "Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton".PMID 18676848
  16. Takeo Fujita et al. (2008). "Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis".PMID 18535175
  17. Jiaxu Wang et al. (2008). "Jab1 is a target of EGFR signaling in ERalpha-negative breast cancer".PMID 18534028
  18. Chunrong Yu et al. (2008). "Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells".PMID 18445700
  19. Nobuyuki Kikuno et al. (2008). "Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells".PMID 18431742
  20. W K K Wu et al. (2008). "Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells".PMID 18414391
  21. Sin Ae Lee et al. (2008). "Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma".PMID 18357344
  22. Zhenhua Song et al. (2008). "Expression of senescence-related genes in human corneal endothelial cells".PMID 18334933
  23. Shuangding Li et al. (2008). "Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development".PMID 18302773
  24. Anjia Han et al. (2008). "Sulindac suppresses beta-catenin expression in human cancer cells".PMID 18291362
  25. Katsuya Tanabe et al. (2008). "Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance".PMID 18288891
  26. Marco A Napolitano et al. (2007). "Brg1 chromatin remodeling factor is involved in cell growth arrest, apoptosis and senescence of rat mesenchymal stem cells".PMID 17666433
  27. Pabbisetty Sudheer Kumar et al. (2007). "Differential expression and role of p21cip/waf1 and p27kip1 in TNF-alpha-induced inhibition of proliferation in human glioma cells".PMID 17565690
  28. Farhang Rabbani et al. (2007). "Prognostic significance of p27Kip1 expression in bladder cancer".PMID 17555476
  29. Eng Hui Chew et al. (2007). "Substrate-mediated regulation of cullin neddylation".PMID 17439941
  30. Bulent Ozpolat et al. (2007). "Programmed cell death-4 tumor suppressor protein contributes to retinoic acid-induced terminal granulocytic differentiation of human myeloid leukemia cells".PMID 17259349
  31. Daniel Lechner et al. (2007). "1alpha,25-dihydroxyvitamin D3 downregulates CYP27B1 and induces CYP24A1 in colon cells".PMID 17029768
  32. Jason W Upton et al. (2006). "Evidence for CDK-dependent and CDK-independent functions of the murine gammaherpesvirus 68 v-cyclin".PMID 17005668
  33. Maryline Paris et al. (2006). "Homeodomain transcription factor Phox2a, via cyclic AMP-mediated activation, induces p27Kip1 transcription, coordinating neural progenitor cell cycle exit and differentiation".PMID 16982676
  34. Louisa S Tang et al. (2006). "COUP-TFI controls Notch regulation of hair cell and support cell differentiation".PMID 16914494
  35. Lihong Peng et al. (2006). "Growth inhibitory concentrations of androgens up-regulate insulin-like growth factor binding protein-3 expression via an androgen response element in LNCaP human prostate cancer cells".PMID 16825320
  36. Kwang Jin Oh et al. (2006). "Deregulation of eIF4E: 4E-BP1 in differentiated human papillomavirus-containing cells leads to high levels of expression of the E7 oncoprotein".PMID 16809313
  37. D Bocangel et al. (2006). "Combinatorial synergy induced by adenoviral-mediated mda-7 and Herceptin in Her-2+ breast cancer cells".PMID 16783343
  38. Laurence Bockstaele et al. (2006). "Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"".PMID 16782892
  39. Joseph F Nabhan et al. (2006). "The 19 S proteasomal subunit POH1 contributes to the regulation of c-Jun ubiquitination, stability, and subcellular localization".PMID 16569633
  40. Tanya Bondar et al. (2006). "Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome".PMID 16537899
  41. Patrice Delobel et al. (2006). "Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1".PMID 16507903
  42. I Ching Wang et al. (2005). "Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase".PMID 16314512
  43. Merav Slotky et al. (2005). "The expression of the ubiquitin ligase subunit Cks1 in human breast cancer".PMID 16168119
  44. Charles E Ducker et al. (2005). "Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis".PMID 16123142
  45. Sung S Kim et al. (2006). "Altered expression of Skp2, c-Myc and p27 proteins but not mRNA after H. pylori eradication in chronic gastritis".PMID 16118628
  46. Devanand Sarkar et al. (2005). "Defining the domains of human polynucleotide phosphorylase (hPNPaseOLD-35) mediating cellular senescence".PMID 16055741
  47. Anja Duursma et al. (2005). "p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation".PMID 16055707
  48. Cheng Zhang et al. (2005). "PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex".PMID 16055704
  49. Resham Bhattacharya et al. (2005). "Regulatory role of dynamin-2 in VEGFR-2/KDR-mediated endothelial signaling".PMID 16049137
  50. Yuichi J Machida et al. (2005). "Acute reduction of an origin recognition complex (ORC) subunit in human cells reveals a requirement of ORC for Cdk2 activation".PMID 15944161
  51. Rukiyah Van Dross et al. (2005). "Constitutively active K-cyclin/cdk6 kinase in Kaposi sarcoma-associated herpesvirus-infected cells".PMID 15870436
  52. Giuseppe Russo et al. (2005). "Expression of cell cycle-regulated proteins pRB2/p130, p107, E2F4, p27, and pCNA in salivary gland tumors: prognostic and diagnostic implications".PMID 15867222
  53. Yong Kim et al. (2005). "Mutation of Cys105 inhibits dimerization of p12CDK2-AP1 and its growth suppressor effect".PMID 15840587
  54. Malika Hamdane et al. (2005). "p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death".PMID 15741232
  55. Hubert Robitaille et al. (2005). "The mitogen-activated protein kinase kinase kinase dual leucine zipper-bearing kinase (DLK) acts as a key regulator of keratinocyte terminal differentiation".PMID 15695824
  56. Hiroko Furumoto et al. (2005). "An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis".PMID 15601836
  57. Bing Zhu et al. (2005). "Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells".PMID 15526282
  58. Joao T Barata et al. (2004). "Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells".PMID 15353558
  59. Iain Brown et al. (2004). "Reduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cells".PMID 15318941
  60. Debra L Bemis et al. (2004). "A concentrated aglycone isoflavone preparation (GCP) that demonstrates potent anti-prostate cancer activity in vitro and in vivo".PMID 15297432
  61. Vidya Mamidipudi et al. (2004). "RACK1 regulates G1/S progression by suppressing Src kinase activity".PMID 15254245
  62. Larissa S Agapova et al. (2004). "Activation of Ras-Ral pathway attenuates p53-independent DNA damage G2 checkpoint".PMID 15208305
  63. Chitkala Satyanarayana et al. (2004). "DRF 3188 a novel semi-synthetic analog of andrographolide: cellular response to MCF 7 breast cancer cells".PMID 15207007
  64. Sung Kwon Moon et al. (2004). "Disialoganglioside (GD3) synthase gene expression suppresses vascular smooth muscle cell responses via the inhibition of ERK1/2 phosphorylation, cell cycle progression, and matrix metalloproteinase-9 expression".PMID 15175338
  65. Doina Ivan et al. (2004). "Expression of cell cycle inhibitor p27Kip1 and its inactivator Jab1 in melanocytic lesions".PMID 15154004
  66. Antonio Marchini et al. (2004). "The short stature homeodomain protein SHOX induces cellular growth arrest and apoptosis and is expressed in human growth plate chondrocytes".PMID 15145945
  67. Bernard Gary et al. (2004). "Interaction of Nkx3.1 and p27kip1 in prostate tumor initiation".PMID 15111307
  68. Ashka Y Pandya et al. (2004). "Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer".PMID 15102675
  69. Hirotoshi Dosaka-Akita et al. (2004). "Expression of N-acetylglucosaminyltransferase v is associated with prognosis and histology in non-small cell lung cancers".PMID 15014031
  70. Nozomi Sugimoto et al. (2004). "Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding".PMID 14993212
  71. Maria Carla Motta et al. (2004). "Mammalian SIRT1 represses forkhead transcription factors".PMID 14980222
  72. Christina R Kahl et al. (2004). "Regulation of cyclin D1/Cdk4 complexes by calcium/calmodulin-dependent protein kinase I".PMID 14754892
  73. Timothy J King et al. (2004). "Mice deficient for the gap junction protein Connexin32 exhibit increased radiation-induced tumorigenesis associated with elevated mitogen-activated protein kinase (p44/Erk1, p42/Erk2) activation".PMID 14742325
  74. Lenin Mahimainathan et al. (2004). "Inactivation of platelet-derived growth factor receptor by the tumor suppressor PTEN provides a novel mechanism of action of the phosphatase".PMID 14718524
  75. Francisco J Esteva et al. (2003). "Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer".PMID 14654548
  76. Frederick Y Wu et al. (2003). "Cell cycle arrest by Kaposi's sarcoma-associated herpesvirus replication-associated protein is mediated at both the transcriptional and posttranslational levels by binding to CCAAT/enhancer-binding protein alpha and p21(CIP-1)".PMID 12885907
  77. Soichi Tsutsumi et al. (2003). "Regulation of cell proliferation by autocrine motility factor/phosphoglucose isomerase signaling".PMID 12783864
  78. Qiou Wei et al. (2003). "The Sp1 family of transcription factors is involved in p27(Kip1)-mediated activation of myelin basic protein gene expression".PMID 12773549
  79. Stephanie J Moeller et al. (2003). "p27Kip1 inhibition of GRB2-SOS formation can regulate Ras activation".PMID 12748278
  80. Ole J Halvorsen et al. (2003). "Combined loss of PTEN and p27 expression is associated with tumor cell proliferation by Ki-67 and increased risk of recurrent disease in localized prostate cancer".PMID 12684422
  81. Hesham M Amin et al. (2003). "Characterization of 4 mantle cell lymphoma cell lines".PMID 12683869
  82. Ursula G B Haider et al. (2003). "Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells".PMID 12644594
  83. George Z Rassidakis et al. (2003). "Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma".PMID 12631617
  84. Xianmin Xia et al. (2003). "The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrest".PMID 12588990
  85. Michael K Connor et al. (2003). "CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis".PMID 12529437
  86. Norio Komatsu et al. (2003). "A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells".PMID 12456669
  87. Heidi L Kenerson et al. (2002). "Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors".PMID 12384518
  88. Irene H L Hamelers et al. (2002). "Insulin-like growth factor I triggers nuclear accumulation of cyclin D1 in MCF-7S breast cancer cells".PMID 12364325
  89. Pier Paolo Claudio et al. (2002). "Expression of cell-cycle-regulated proteins pRb2/p130, p107, p27(kip1), p53, mdm-2, and Ki-67 (MIB-1) in prostatic gland adenocarcinoma".PMID 12060621
  90. Hyesun Oh et al. (2002). "Negative regulation of cell growth and differentiation by TSG101 through association with p21(Cip1/WAF1)".PMID 11943869
  91. Sandra Ciarallo et al. (2002). "Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrest".PMID 11940657
  92. David M Loeb et al. (2002). "Cyclin E is a target of WT1 transcriptional repression".PMID 11919196
  93. Kevin A Walter et al. (2002). "Scatter factor/hepatocyte growth factor stimulation of glioblastoma cell cycle progression through G(1) is c-Myc dependent and independent of p27 suppression, Cdk2 activation, or E2F1-dependent transcription".PMID 11909963
  94. Rebecca G Carey et al. (2002). "Pituitary adenylate cyclase activating polypeptide anti-mitogenic signaling in cerebral cortical progenitors is regulated by p57Kip2-dependent CDK2 activity".PMID 11880488
  95. Hong Xia et al. (2002). "LATS1 tumor suppressor regulates G2/M transition and apoptosis".PMID 11850843
  96. Wei Liu et al. (2002). "Vitamin D arrests thyroid carcinoma cell growth and induces p27 dephosphorylation and accumulation through PTEN/akt-dependent and -independent pathways".PMID 11839571
  97. Tara Ann Santore et al. (2002). "Adenovirus-directed expression of Q227L-G alpha(s) inhibits growth of established tumors of later-stage human breast cancer cells in athymic mice".PMID 11805301
  98. Cynthia C Sprenger et al. (2002). "Over-expression of insulin-like growth factor binding protein-related protein-1(IGFBP-rP1/mac25) in the M12 prostate cancer cell line alters tumor growth by a delay in G1 and cyclin A associated apoptosis".PMID 11791184
  99. Zhongfa Yan et al. (2002). "Transforming growth factor beta 1 induces proliferation in colon carcinoma cells by Ras-dependent, smad-independent down-regulation of p21cip1".PMID 11784716
  100. Maria Felice Brizzi et al. (2002). "Diabetic LDL inhibits cell-cycle progression via STAT5B and p21(waf)".PMID 11781356
  101. Tracy Tzu Ling Tang et al. (2002). "The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor".PMID 11777915
  102. Andrew J Skildum et al. (2002). "The cyclin-dependent kinase inhibitor p21WAF1/Cip1 is an antiestrogen-regulated inhibitor of Cdk4 in human breast cancer cells".PMID 11741909
  103. Tadashi Yoshii et al. (2002). "Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest".PMID 11724777
  104. K Yu et al. (2001). "mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer".PMID 11566616
  105. Y Dai et al. (2001). "Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells".PMID 11431348
  106. K Kurose et al. (2001). "Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas".PMID 11395387
  107. D Y Huang et al. (2001). "Interaction of human thymidine kinase 1 with p21(Waf1)".PMID 11389691
  108. C Indolfi et al. (2001). "Membrane-bound protein kinase A inhibits smooth muscle cell proliferation in vitro and in vivo by amplifying cAMP-protein kinase A signals".PMID 11179200