This is a review about p16, based on 44 published articles (read how Labome selects the articles), using p16 antibody in experiments. It is aimed to help Labome visitors find the most suited p16 antibody.
p16 synonym: ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16; CDK4 inhibitor p16-INK4; cell cycle negative regulator beta; cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); multiple tumor suppressor 1

Santa Cruz BiotechnologySanta Cruz Biotechnology p16 product
  • Santa Cruz Biotechnology antibody which recognizes human ARF was used in western blot to study that p400 is required for E1A to promote apoptosis. (catalog: sc-8340) ncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology15p16 antibodysc-8340
    Thermo Scientific Pierce Products6p16 antibody
    Abcam3p16 antibody
    EMD Millipore1p16 antibody
    BD Biosciences4p16 antibody
    Table 1. p16 antibody western blot.
  • Santa Cruz Biotechnologies anti-p16 antibody (Cat# Sc-1661) was used in immunohistochemistry to study the role for targeting the cytoskeleton in inhibition of metastatic outgrowth from single dormant tumor cells. (catalog: Sc-1661) ncbi, more
  • Santa Cruz Biotechnology anti-Arf antibody was used as primary antibody for immunoblotting in order to suggest that ATM plays a role in oncogene-induced senescence or in p53-dependent tumor suppression.ncbi, more
  • SantaCruz rabbit anti-p16INK4a antibody (N-20) was used in western blot and immunohistochemistry to study the association of the chromatin remodelling factor BRG1 with the tumor suppressor p16INK4ancbi, more
  • Santa Cruz Biotechnology anti-p19 antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation.ncbi, more
  • Santa Cruz Biotechnology p14ARF antibody 1H6B10G7 was used in western blot on to study the regulation of cell proliferation and senescence by Mel-18 via transcriptional repression of Bmi-1 and c-Myc oncoproteinsncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology6p16 antibodySc-1661
    Thermo Scientific Pierce Products5p16 antibody
    Abcam2p16 antibody
    BD Biosciences3p16 antibody
    Dako1
    Table 2. p16 antibody immunohistochemistry.
  • Santa Cruz Biotechnology p16INK4A antibody was used in western blot to study the role of CPEB in cellular senescence.ncbi, more
  • Santa Cruz Biotechnology anti-p16 antibody was used in human HCT116 cells and in immunoprecipitation to study the role for FAT10 in the regulation of chromosomal stability.ncbi, more
  • Santa Cruz Biotechnology p16Ink4a antibody was used in western blot to study the role of Dmp1 in Ras-Raf-Arf signaling.ncbi, more
  • Santa Cruz Biotechnology p16INK4A polyclonal antibody (C-20) was used in immunohistochemistry to study p16INK4A hypermethylation in hepatocellular carcinomancbi, more
  • Santa Cruz Biotech anti- p14ARF/p16INK4a antibody was used in western blot to study the suppression of cyclic GMP-specific phosphodiesterase 5 promoting apoptosis and inhibiting growth in HT29 cells.ncbi, more
  • suppliernumreagent linkcited catalog
    Thermo Scientific Pierce Products2p16 antibody
    Novus Biologicals1p16 antibodyNB200-106
    Santa Cruz Biotechnology1p16 antibody
    BD Biosciences1p16 antibody
    Table 3. p16 antibody immunocytochemistry.
  • Santa Cruz Biotechnology anti-p16 was used in western blot to detect the expression of p16 in tumor tissues from patients with squamous cell carcinoma of the head and neck (SCCHN).ncbi, more
  • Santa Cruz Biotechnology anti-p16INK4A mouse monoclonal F-12 antibody was used in immunohistochemistry p16INK4A, p14ARF, p53, and proliferating cell nuclear antigen expression in cervical cancerncbi, more
  • Santa Cruz Biotechnology p16 antibody was used in western blot to study the role of the DNA methyltransferase variant DNMT3b3 in DNA methylation.ncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal anti-p16 antibody C20 was used in primary human keratinocytes, epidermal SCC line SCC-13 cells and seborrheic keratosis, benign papillary hyperplasia and hyperkeratosis of alveolar ridge epithelium, human foreskin and were used in immunocytochemistry and immunohistochemistry to study the setting in which p16 is expressed and functions as a tumor suppressor in stratified squamous epithelia in vivo.ncbi, more
  • Santa Cruz Biotechnology p16INK4a antibody was used in western blot at dilutions of 1:500 to 1:1000 to facilitate the establishment of an in vitro model that can be reliably used to study the pathogenesis of MCL.ncbi, more
  • suppliernumreagent link
    Thermo Scientific Pierce Products2p16 antibody
    Life Technologies Corporation1
    Santa Cruz Biotechnology1p16 antibody
    Table 4. p16 antibody immunoprecipitation.
  • Santa Cruz Biotechnology antibody against human p16 was used in western blot to study the RB activation defect in tumor cell lines.ncbi, more
  • Santa Cruz Biotechnology goat anti-p14ARF antibody was used in western blot to study the induction of extracellular matrix-remodeling genes by the senescence-associated protein APA-1.ncbi, more
  • Santa Cruz Biotechnology anti-p16 antibody was used in western blot to study the role of Tbx3 in p53 pathway.ncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal anti-p14/ARF antibody was used in western blot to study expression of p53, ErbB1, ErbB2, and Raf-1 in lung cancer.ncbi, more
  • Santa Cruz Biotechnology polyclonal anti-Arf antibody was used in human cells (HT1080 fibrosarcoma, A375 melanoma, RD rhabdomyosarcoma cells) and in western blot to study the role for integrins in regulating the apoptotic response to DNA damage.ncbi, more
  • Novus Biologicals antibody which recognizes p19ARF was used in immunocytochemistry to study that p400 is required for E1A to promote apoptosis. (catalog: NB200-106) ncbi, more
  • Oncogene Research Products anti-p16 antibody was used in western blot to study the effects of over-expression of the potential tumor suppressor gene IGFBP-rP1/mac25 on cell-cycle kinetics in human prostate cancer cells.ncbi, more
Thermo Scientific Pierce ProductsThermo Scientific Pierce Products p16 product
  • NeoMarkers p19Arf antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence.ncbi, more
  • Lab Vision rabbit polyclonal anti-p16 antibody (1:50) was used in immunohistochemistry in order to investigate the expression of p16INK4a, p21WAF1/CIP1, p27KIP1, and p53 in human corneal endothelial cell (HCEC) senescence ex vivo at various donor agesncbi, more
  • ABR Affinity Bioreagents anti-Arf monoclonal antibody was used to perform immunocytochemistry in order to investigate the relations between PI4P and GGA.ncbi, more
  • Neomarkers monoclonal anti-p16 antibody (DCS-50) was used in human IMR-90 cells and in western blot, immunoprecipitation to study the role for cyclins and CDK "inhibitors" in Thr172 phosphorylation of CDK4.ncbi, more
  • NeoMarker p16 antibody was used in western blot to investigate the effect of mitochondrial stress on p21 expression and cell apoptosisncbi, more
  • Neomarkers p14ARF antibody was used in western blot to study p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2ncbi, more
  • Labvision anti-p16 antibody was used in immunohistochemistry to study the interaction of the loss of expression of the adipocyte-type fatty acid-binding protein (A-FABP) with progression of human urothelial carcinomas.ncbi, more
  • Neomarkers rabbit polyclonal Ab-4 anti-p14ARF antibody was used in immunohistochemistry p16INK4A, p14ARF, p53, and proliferating cell nuclear antigen expression in cervical cancerncbi, more
  • Neomarkers mouse monoclonal ARF (14PO2) antibody was used in western blot to study the effect of MDM2 on MDMXncbi, more
  • Neomarkers mouse monoclonal anti-p16INK4a antibody (clone 16P07) was used in immunohistochemistry and immunocytochemistry to study the effect of hypoxia on erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its role in cervical carcinogenesis and tumor progression.ncbi, more
  • Affinity BioReagents anti-ARF antibody was used in western blot and immunoprecipitation to study the interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1).ncbi, more
  • Abcam mouse anti-human P16 antibody(Ab50282) was used to perform western blot in order to study the role of polycomb CBX7 in H3K9me3.ncbi, more
  • Abcam rat ARF antibody was used in immunohistochemistry in order to show the importance of protection of the ATM-mediated DDR-p53 signaling pathway for breast cancer prevention.ncbi, more
  • Abcam anti-Arf antibody was used as primary antibody for immunoblotting in order to suggest that ATM plays a role in oncogene-induced senescence or in p53-dependent tumor suppression.ncbi, more
  • Abcam rabbit polyclonal p16 antibody was used for western blot in order to investigate the role of Aurora B in the regulation of postmitotic endoreduplication checkpoint.ncbi, more
  • Abcam rabbit anti-p19Arf was used to perform immunohistochemistry in order to illustrate that the Bmi1 functions on neurons oxidative metabolism are associated with repression of p53 pro-oxidant activity.ncbi, more
Life Technologies Corporation
  • Zymed Laboratories mouse anti-p16INK4a antibody (2B4D11) was used in immunoprecipitation to study the association of the chromatin remodelling factor BRG1 with the tumor suppressor p16INK4ancbi, more
  • BD Pharmingen monoclonal anti-P16INK4 was used in 1:200 to perform immunohistochemistry in order to show the mutational spectrum of head and neck squamous cell carcinomancbi, more
  • BD Bioscience anti-human p16 antibody was used in western blot to investigate the expression and localization of H2RSP in normal, injured, and neoplastic human intestinal tissue.ncbi, more
  • BD Biosciences anti-p16 antibody was used in human carcinoma cells and in western blot to study the effect of DNA damage-induced expression of p53 on mitotic checkpoint kinase hMps1.ncbi, more
  • BD Biosciences mouse monoclonal p16 antibody was used in western blot to detect the expression of p16 in the human metastatic melanoma cell line HO-1ncbi, more
  • BD Biosciences PharMingen anti-p16INK4a antibody G175-405 was used in human mesenchymal stem cells (hMSCs) and in western blot to study the prolongation of life span of human umbilical cord blood-derived mesenchymal stem cells (UCBMSCs).ncbi, more
  • PharMingen mouse monoclonal 16 (CDKN2A; Clone G175 1239) antibody was used to study p16 methylation in nonadenomatous pituitaries from Cushing s disease patientsncbi, more
  • PharMingen mouse monoclonal anti-p16 antibody (G175 405) was used in primary human keratinocytes, epidermal SCC line SCC-13 cells and seborrheic keratosis, benign papillary hyperplasia and hyperkeratosis of alveolar ridge epithelium, human foreskin and were used in immunocytochemistry and immunohistochemistry to study the setting in which p16 is expressed and functions as a tumor suppressor in stratified squamous epithelia in vivo.ncbi, more
Dako
  • Dako rabbit p16 polyclonal antibody was used in immunohistochemistry to study cyclin D1, p16, and retinoblastoma protein expressions in gallbladder carcinomancbi, more
ONCOGENE LABORATORIES
  • Oncogene Laboratories mouse anti-p16 monoclonal antibody was used in western blot and immunocytochemistry to detect p16 in the human PEL cell line BCBL1ncbi, more
Articles Reviewed
  1. Nicolas Stransky et al. (2011). "The mutational landscape of head and neck squamous cell carcinoma".PMID 21798893
  2. Qiang Li et al. (2010). "Polycomb CBX7 directly controls trimethylation of histone H3 at lysine 9 at the p16 locus".PMID 21060834
  3. Hui Kuan Lin et al. (2010). "Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence".PMID 20237562
  4. Jay P Reddy et al. (2010). "Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation".PMID 20133707
  5. Alejo Efeyan et al. (2009). "Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression".PMID 19421407
  6. Jayasree S Nair et al. (2009). "Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780".PMID 19225156
  7. Therese M Becker et al. (2009). "The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a".PMID 19149898
  8. Wassim Chatoo et al. (2009). "The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity".PMID 19144853
  9. Dalit Barkan et al. (2008). "Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton".PMID 18676848
  10. Yelena Lyustikman et al. (2008). "Constitutive activation of Raf-1 induces glioma formation in mice".PMID 18472967
  11. Zhenhua Song et al. (2008). "Expression of senescence-related genes in human corneal endothelial cells".PMID 18334933
  12. Jing Wang et al. (2007). "PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal".PMID 17494868
  13. Wei jian Guo et al. (2007). "Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins".PMID 17151361
  14. Irina Groisman et al. (2006). "Control of cellular senescence by CPEB".PMID 17015432
  15. S Uchiyama et al. (2007). "Enhanced expression of hepatocyte growth factor activator inhibitor type 2-related small peptide at the invasive front of colon cancers".PMID 16809422
  16. Laurence Bockstaele et al. (2006). "Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"".PMID 16782892
  17. Jianwei Ren et al. (2006). "FAT10 plays a role in the regulation of chromosomal stability".PMID 16495226
  18. Mandar R Bhonde et al. (2006). "DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis".PMID 16446370
  19. Devanand Sarkar et al. (2005). "Defining the domains of human polynucleotide phosphorylase (hPNPaseOLD-35) mediating cellular senescence".PMID 16055741
  20. Ching Hao Li et al. (2005). "Chloramphenicol-induced mitochondrial stress increases p21 expression and prevents cell apoptosis through a p21-dependent pathway".PMID 15905168
  21. Mark W Jackson et al. (2005). "p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2".PMID 15827088
  22. Andrew V Samuelson et al. (2005). "p400 is required for E1A to promote apoptosis".PMID 15741165
  23. Gita Ohlsson et al. (2005). "Loss of expression of the adipocyte-type fatty acid-binding protein (A-FABP) is associated with progression of human urothelial carcinomas".PMID 15734831
  24. Hong Bing Ma et al. (2005). "Association of cyclin D1, p16 and retinoblastoma protein expressions with prognosis and metastasis of gallbladder carcinoma".PMID 15655836
  25. Masanori Terai et al. (2005). "Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway".PMID 15647378
  26. Ramesh Sreeramaneni et al. (2005). "Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor".PMID 15601844
  27. Xin Li et al. (2004). "p16INK4A hypermethylation is associated with hepatitis virus infection, age, and gender in hepatocellular carcinoma".PMID 15569978
  28. Bing Zhu et al. (2005). "Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells".PMID 15526282
  29. Shadan Ali et al. (2004). "Cytochrome p450 and glutathione transferase expression in squamous cell cancer".PMID 15240530
  30. Jian Liu Wang et al. (2004). "Predictive significance of the alterations of p16INK4A, p14ARF, p53, and proliferating cell nuclear antigen expression in the progression of cervical cancer".PMID 15073118
  31. David J Simpson et al. (2004). "Molecular pathology shows p16 methylation in nonadenomatous pituitaries from patients with Cushing's disease".PMID 15014032
  32. Daniel J Weisenberger et al. (2004). "Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation".PMID 14757847
  33. Frederick Y Wu et al. (2003). "Cell cycle arrest by Kaposi's sarcoma-associated herpesvirus replication-associated protein is mediated at both the transcriptional and posttranslational levels by binding to CCAAT/enhancer-binding protein alpha and p21(CIP-1)".PMID 12885907
  34. Easwar Natarajan et al. (2003). "Co-expression of p16(INK4A) and laminin 5 gamma2 by microinvasive and superficial squamous cell carcinomas in vivo and by migrating wound and senescent keratinocytes in culture".PMID 12875969
  35. Yu Pan et al. (2003). "MDM2 promotes ubiquitination and degradation of MDMX".PMID 12860999
  36. Geza Acs et al. (2003). "Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression".PMID 12759237
  37. Hesham M Amin et al. (2003). "Characterization of 4 mantle cell lymphoma cell lines".PMID 12683869
  38. Philip Ian Padilla et al. (2003). "Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): effects of FK506".PMID 12606707
  39. Cristina BroceƱo et al. (2002). "RB activation defect in tumor cell lines".PMID 12379745
  40. Jennifer A Benanti et al. (2002). "Induction of extracellular matrix-remodeling genes by the senescence-associated protein APA-1".PMID 12370286
  41. Hanqian Carlson et al. (2002). "Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation".PMID 12032820
  42. Xiaodan Yu et al. (2002). "Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228".PMID 11929951
  43. Jean McArthur Lewis et al. (2002). "Integrins regulate the apoptotic response to DNA damage through modulation of p53".PMID 11904424
  44. Cynthia C Sprenger et al. (2002). "Over-expression of insulin-like growth factor binding protein-related protein-1(IGFBP-rP1/mac25) in the M12 prostate cancer cell line alters tumor growth by a delay in G1 and cyclin A associated apoptosis".PMID 11791184