This is a review about mTOR, based on 28 published articles (read how Labome selects the articles), using mTOR antibody in experiments. It is aimed to help Labome visitors find the most suited mTOR antibody.
mTOR synonym: FRAP; FRAP1; FRAP2; RAFT1; RAPT1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP12-rapamycin complex-associated protein 1; mammalian target of rapamycin; rapamycin and FKBP12 target 1; rapamycin associated protein FRAP2; rapamycin target protein 1; serine/threonine-protein kinase mTOR

  • Upstate Biotechology rabbit anti-raptor antibody was used in western blot to identify the pathway and mechanism by which AAs signal to hVps34 to stimulate mTOR complex1 signaling.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology3mTOR antibody
    EMD Millipore2mTOR antibody
    Novus Biologicals1
    Cell Signaling Technology19mTOR antibody
    BD Biosciences3
    Table 1. mTOR antibody western blot.
  • Upstate anti-phospho-mTOR Ser-2481, anti-phospho-mTOR Ser-2448 and anti-mTOR antibodies were used in human A549 cells and were used in western blot, immunoprecipitation to study the effect of mammalian target of rapamycin on the activation of STAT1.ncbi, more
  • Santa Cruz polyclonal anti-mTOR (N-19 (alpha-FRAP) was used to perform western blot in order to show that mTOR is identified as a regulator of p73 by a gene signature-based approach.ncbi, more
  • Santa Cruz Biotechology anti-FRAP (N19) antibody was used in western blot to identify the pathway and mechanism by which AAs signal to hVps34 to stimulate mTOR complex1 signaling.ncbi, more
  • SCBT anti-mTOR antibody was used in immunoprecipitation to identify S6 Kinase 1 as a mTOR-phosphorylating kinasencbi, more
  • Santa Cruz Biotech anti-FRAP antibody was used in western blot to study the inhibition of lysophosphatidic acid acyltransferase beta on proliferative and survival signals in normal cells and apoptosis of tumor cells.ncbi, more
  • suppliernumreagent link
    EMD Millipore1mTOR antibody
    Santa Cruz Biotechnology1mTOR antibody
    Cell Signaling Technology1mTOR antibody
    Table 2. mTOR antibody immunoprecipitation.
Novus Biologicals
  • Novus Biologicals anti-mTor antibody was used for western blot in order to investigate the role of BPAG1e in the regulation the activities of Rac 1 and Cofilinncbi, more
  • Cell Signaling Technology anti-phospho-S2481 mTOR was used to perform western blot in order to show that how growth factor signaling is inhibited by mTOR through mTOR-regulated phosphoproteome.ncbi, more , figure 1
  • Figure 1
    mTOR antibody western blot Cell Signaling Technology
    mTOR antibody western blot Cell Signaling Technology
    Known mTOR pathway phosphorylations in HEK-293E cells serum starved for 4 hrs, treated with 100 nM rapamycin, 250 nM Torin1 or vehicle control for 1 hr, and then stimulated where indicated with 150 nM insulin for 20 min or TSC2+/+ and TSC2-/- MEFs
    Peggy P Hsu et al. (2011). "The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling".PMID 21659604
  • Cell Signaling Technology anti-mTOR antibody was used to carry out western blot analysis in order to investigate the precise contribution of 4E-BPs to mTORC1 signaling.ncbi, more
  • Cell Signaling anti-mTOR was used to perform western blot and immunocytochemistry in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation.ncbi, more
  • Cell Signaling anti-mTOR antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins.ncbi, more
  • Cell Signaling Technology rabbit anti-mTOR antibody was used to carry out western blot analysis in order to investigate the function for beta3 integrin-mediated vimentin IF recruitment to the cell surface.ncbi, more
  • Cell Signaling rabbit anti-phospho mTOR Ser2448 antibody was used in immunoblots to detect cell lysate in order to confirm that autophagy can sensitize apoptosis deprivation of growth factors.ncbi, more
  • Cell Signaling anti-phospho-mTOR (Ser 2448) was used to perform immunohistochemistry in dilution 1:50 in order to show that AXL and SHC1 expression disregulation may be associated with pathogenesis of endometriosis.ncbi, more
  • suppliernumreagent link
    Cell Signaling Technology3mTOR antibody
    Table 3. mTOR antibody immunohistochemistry.
  • Cell Signaling Technology anti-mTOR antibody was used to carry out western blot analysis in order to investigate the regulation of insulin-induced translational activation of TOP mRNAs by TSC-mTOR pathway.ncbi, more
  • Cell Signaling anti-mTOR antibody was used in western blot in order to study the role of S6K1 in glial transformationncbi, more
  • Cell Signaling Technology mTOR Ser2448 antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathwayncbi, more
  • Cell Signaling phosphorylated-mTOR (Ser2448) antibody was used in western blot in order to provide evidence for a dual role of AMPK activation in the protection of normal brain from energy stress while also killing the brain tumor cellsncbi, more
  • Cell Signaling Technologies anti-mTOR antibody was used in western blot and immunoprecipitation to identify the pathway and mechanism by which AAs signal to hVps34 to stimulate mTOR complex1 signaling.ncbi, more
  • suppliernumreagent link
    Cell Signaling Technology2mTOR antibody
    BD Biosciences1
    Table 4. mTOR antibody immunocytochemistry.
  • Cell Signaling Technology rabbit anti-mTOR antibody was used for western blot in order to investigate the role of eIF4GI in the regulation of cell proliferation and autophagy.ncbi, more
  • Cell Signaling Technology phosphorylated phosphorylated S2448 mTOR antibody (1:1000 dilution) was used in western blot in order to study molecular mechanisms underlying TSH-secreting pituitary tumors (TSHomas)ncbi, more
  • Cell Signaling Technology phosphorylated phosphorylated S2448 mTOR antibody (1:500 dilution) was used in western blot in order to study molecular mechanisms underlying TSH-secreting pituitary tumors (TSHomas)ncbi, more
  • Cell Signaling anti-phospho-mTOR antibody(1:1,000) was used to perform western blot in order to investigate the role of the mTOR signaling pathway in the synthesis of human muscle protein.ncbi, more
  • Cell Signaling Technology anti-mTOR antibody (phosphorylated) was used in western blot to study the mechanism of protein synthesis inhibition by hypoxia in human breast cancer cells.ncbi, more
  • suppliernum
    BD Biosciences1
    Table 5. mTOR antibody block or activate.
  • Cell Signaling Technology antibody against mTOR was used in western blot to study the critical role of the mTOR-dependent suppression of protein phosphatase 2A for phospholipase D survival signals in human breast cancer cells.ncbi, more
  • Cell Signaling phospho-mTOR (Ser-2448) antibody was used in western blot and immunohistochemistry to investigate the activation of phosphatidylinositol 3-kinase/Akt and transformation by NBS1ncbi, more
  • Cell Signaling Technology anti-mTOR and anti-phospho-mTOR (Ser2448) antibodies were used in paraffin sections from human hepatocellular tumors and in immunohistochemistry to study the role of mTOR and S6K in hepatocellular carcinoma.ncbi, more
  • Cell Signaling Technology anti-total and phosphorylated mTOR antibody was used in western blot to detect total and phosphorylated mTOR in PANC-1 and P/ARK cell lines.ncbi, more
  • Cell Signalling Tech anti-mTOR antibody was used in western blot to study the inhibition of lysophosphatidic acid acyltransferase beta on proliferative and survival signals in normal cells and apoptosis of tumor cells.ncbi, more
  • Cell Signaling antibody that specifically recognize phosphorylated mTOR at Ser2448 was used in immunohistochemistry to study the expression of mTOR in human TSC tumors and normal kidney.ncbi, more
BD Biosciences
  • Transduction Laboratories mTOR antibody was used in western blot to study the role of protein phosphatase 5 in signal-regulating kinase 1 signaling rapamycin inhibition activated apoptosis.ncbi, more
  • BD Biosciences anti-mTOR antibody was used in human A549 cells and in western blot to study the effect of mammalian target of rapamycin on the activation of STAT1.ncbi, more
  • BD Transduction Laboratories monoclonal mTOR/FRAP antibody was used in western blot, immunocytochemistry, and blocking experiments to study the role of phosphorylation of p53S15 by mTOR/FRAP in syncytial apoptosis driven by HIV-1 Env.ncbi, more
Articles Reviewed
  1. Roberto Zoncu et al. (2011). "mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase".PMID 22053050
  2. Peggy P Hsu et al. (2011). "The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling".PMID 21659604
  3. Masako Narita et al. (2011). "Spatial coupling of mTOR and autophagy augments secretory phenotypes".PMID 21512002
  4. Ryan J O Dowling et al. (2010). "mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs".PMID 20508131
  5. Kevin J Hamill et al. (2009). "BPAG1e maintains keratinocyte polarity through beta4 integrin-mediated modulation of Rac1 and cofilin activities".PMID 19403692
  6. Ramona Bhattacharya et al. (2009). "Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength".PMID 19366731
  7. Brian J Altman et al. (2009). "Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis".PMID 19109422
  8. Hiroshi Honda et al. (2008). "Serial analysis of gene expression reveals differential expression between endometriosis and normal endometrium. Possible roles for AXL and SHC1 in the pathogenesis of endometriosis".PMID 19055724
  9. Ilona Patursky-Polischuk et al. (2009). "The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner".PMID 19047368
  10. Jean L Nakamura et al. (2008). "S6K1 plays a key role in glial transformation".PMID 18701474
  11. Jennifer M Rosenbluth et al. (2008). "A gene signature-based approach identifies mTOR as a regulator of p73".PMID 18678646
  12. P L Greenhaff et al. (2008). "Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle".PMID 18577697
  13. Purna Mukherjee et al. (2008). "Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain".PMID 18474106
  14. Pawan Gulati et al. (2008). "Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34".PMID 18460336
  15. Francisco Ramírez-Valle et al. (2008). "eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy".PMID 18426977
  16. Changxue Lu et al. (2008). "Activation of phosphatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors".PMID 18356276
  17. Hans C Dreyer et al. (2008). "Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle".PMID 18056791
  18. Eileen Connolly et al. (2006). "Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells".PMID 16648488
  19. Li Hui et al. (2005). "mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells".PMID 16109716
  20. Yen Chung Chen et al. (2005). "Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt".PMID 16036916
  21. Marina K Holz et al. (2005). "Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase".PMID 15905173
  22. Fikret Sahin et al. (2004). "mTOR and P70 S6 kinase expression in primary liver neoplasms".PMID 15623621
  23. Shile Huang et al. (2004). "Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity".PMID 15218033
  24. Atsushi Suzuki et al. (2004). "ARK5 is a tumor invasion-associated factor downstream of Akt signaling".PMID 15060171
  25. Michael Coon et al. (2003). "Inhibition of lysophosphatidic acid acyltransferase beta disrupts proliferative and survival signals in normal cells and induces apoptosis of tumor cells".PMID 14578472
  26. Arnold S Kristof et al. (2003). "Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin".PMID 12807916
  27. Heidi L Kenerson et al. (2002). "Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors".PMID 12384518
  28. M Castedo et al. (2001). "Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation".PMID 11602639