This is a review about integrin alpha2, based on 39 published articles (read how Labome selects the articles), using integrin alpha2 antibody in all methods. It is aimed to help Labome visitors find the most suited integrin alpha2 antibody.
integrin alpha2 synonym: CD49B; GPIa; HPA-5; VLA-2; VLAA2; CD49 antigen-like family member B; alpha 2 subunit of VLA-2 receptor; collagen receptor; human platelet alloantigen system 5; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit

EMD Millipore
mouse monoclonal (P1E6)
  • FC; human
In order to determine the role of growth factors in EMT, EMD Millipore integrin alpha2 antibody (Millipore, P1E6) was used in flow cytometry on human samples. PLoS ONE (2015) ncbi
rabbit polyclonal
  • WB; human; 1:1000
EMD Millipore integrin alpha2 antibody (Millipore, AB1936) was used in western blot on human samples at 1:1000. J Cell Biochem (2015) ncbi
mouse monoclonal (BHA2.1)
  • Neut; human
EMD Millipore integrin alpha2 antibody (Merck Millipore, MAB1998Z) was used in neutralization on human samples. Biomaterials (2015) ncbi
mouse monoclonal (P1E6)
  • Neut; human; 1:50
  • FC; human; 1:200
In order to investigate the effect of glycosylation on tumor cell adhesion and invasion and its mechanism, EMD Millipore integrin alpha2 antibody (Chemicon, P1E6) was used in neutralization on human samples at 1:50 and in flow cytometry on human samples at 1:200. PLoS ONE (2014) ncbi
mouse monoclonal (P1E6)
  • FC; human
EMD Millipore integrin alpha2 antibody (Millipore, P1E6) was used in flow cytometry on human samples. PLoS ONE (2014) ncbi
mouse monoclonal (P1E6)
  • Neut; human; 10 ug/ml
  • FC; human; 2 ug/25 x104cells
EMD Millipore integrin alpha2 antibody (Millipore, P1E6) was used in neutralization on human samples at 10 ug/ml and in flow cytometry on human samples at 2 ug/25 x104cells. Oncogene (2015) ncbi
mouse monoclonal (P1E6)
  • WB; human
EMD Millipore integrin alpha2 antibody (Millipore, P1E6) was used in western blot on human samples. PLoS ONE (2013) ncbi
mouse monoclonal (10G11)
  • Neut; human
EMD Millipore integrin alpha2 antibody (Millipore, MAB1988) was used in neutralization on human samples. Oncogene (2014) ncbi
mouse monoclonal (BHA2.1)
  • Neut; human
EMD Millipore integrin alpha2 antibody (Chemicon, MAB1998) was used in neutralization on human samples. Int J Cell Biol (2013) ncbi
mouse monoclonal (P1E6)
  • IHC-F; human; 1:100
  • FC; human
EMD Millipore integrin alpha2 antibody (Millipore, MAB1950Z) was used in immunohistochemistry - frozen section on human samples at 1:100 and in flow cytometry on human samples. J Orthop Res (2013) ncbi
mouse monoclonal (P1E6)
  • IC; human
In order to determine the composition of focal adhesion cultured on titanium surface., EMD Millipore integrin alpha2 antibody (Merck Millipore, MAB1950Z) was used in immunocytochemistry on human samples. J Biomed Mater Res A (2014) ncbi
mouse monoclonal (P1E6)
  • FC; human
EMD Millipore integrin alpha2 antibody (Millipore, P1E6) was used in flow cytometry on human samples. Am J Respir Cell Mol Biol (2013) ncbi
mouse monoclonal (P1E6)
  • IC; human; 1:40
EMD Millipore integrin alpha2 antibody (Millipore, MAB1950) was used in immunocytochemistry on human samples at 1:40. BMC Cancer (2013) ncbi
mouse monoclonal (P1E6)
  • IC; human
EMD Millipore integrin alpha2 antibody (Millipore, P1E6) was used in immunocytochemistry on human samples. Toxicol Appl Pharmacol (2013) ncbi
mouse monoclonal (P1E6)
  • Neut; human
EMD Millipore integrin alpha2 antibody (Millipore, MAB1950) was used in neutralization on human samples. Clin Cancer Res (2013) ncbi
not indicated
  • WB; human
Chemicon monoclonal anti-integrin alpha2 antibody (clone P1E6) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells.J Biol Chem (2006) ncbi
not indicated
  • IP; human
  • Neut; human
CHEMICON International anti-alpha2-beta1 (clone BHA2.1, JBS2) antibodies were used in immunoprecipitation and blocking experiment to study the regulation of the endothelial cell response to Ang-1 through stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor.J Cell Biol (2005) ncbi
not indicated
  • WB; human
Chemicon integrin alpha2 antibody were used in western blot to investigate the involvement of TGFB1, PKC delta, and integrin in the mobility of gastric carcinoma cells.Mol Cell Biol (2005) ncbi
not indicated
  • Neut; human
Chemicon anti-integrins alpha-2 antibody was used in blocking or activating expriments to study the role for hepatocyte growth factor in promoting lymphatic vessel formation and function in human dermal BVEC and LEC.EMBO J (2005) ncbi
not indicated
  • Neut; human
Upstate Biotechnology monoclonal antibody against the integrin alpha2 subunit was used in blocking experiments to study the function of cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5) to support chondrocyte attachment through interaction with integrinsJ Biol Chem (2005) ncbi
not indicated
  • Neut; human
Chemicon International rabbit polyclonal anti-integrin alpha2 antibody was used in blocking or activating expriments to study the role of uPAR in cross-talk between FPR and alphavbeta5.J Biol Chem (2005) ncbi
not indicated
  • FC; human
  • Neut; human
Chemicon monoclonal anti-integrin alpha-2 (P1E6) antibody was used in flow cytometry and blocking experiment to study the beta-ig-h3-mediated keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha-3, beta-1, and the phosphatidylinositol 3-kinase/Akt signaling pathway.J Biol Chem (2005) ncbi
R and D Systems
mouse monoclonal (HAS3) R and D Systems integrin alpha2 antibody (B&D, MAB1233) was used . Acta Cir Bras (2015) ncbi
mouse monoclonal (HAS3)
  • IC; human
R and D Systems integrin alpha2 antibody (R&D Systems, BAM1233) was used in immunocytochemistry on human samples. J Biol Chem (2014) ncbi
mouse monoclonal (HAS3)
  • FC; human
In order to study the role of alpha-4 integrin in the mechanism by which CD82 modulates cell adhesion, R and D Systems integrin alpha2 antibody (R&D, HAS3) was used in flow cytometry on human samples. Mol Biol Cell (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-9)
  • WB; human
Santa Cruz Biotechnology integrin alpha2 antibody (Santa Cruz Biotechnology, sc-74466) was used in western blot on human samples. Colloids Surf B Biointerfaces (2015) ncbi
rabbit polyclonal (H-293)
  • WB; rat; 1:8000
  • IHC; rat; 1:200
Santa Cruz Biotechnology integrin alpha2 antibody (Santa Cruz Biotechnology, sc-9089) was used in western blot on rat samples at 1:8000 and in immunohistochemistry on rat samples at 1:200. Cell Tissue Res (2014) ncbi
rabbit polyclonal (H-293)
  • FC; mouse
In order to study Pigment epithelium-derived factor expression in regards to regulation of phenotypes of the lung endothelium, Santa Cruz Biotechnology integrin alpha2 antibody (Santa Cruz, sc-9089) was used in flow cytometry on mouse samples. Am J Physiol Lung Cell Mol Physiol (2014) ncbi
AbD Serotec (Bio-Rad)
mouse monoclonal (AK7)
  • FC; human
AbD Serotec (Bio-Rad) integrin alpha2 antibody (Serotec, MCA743PET) was used in flow cytometry on human samples. Br J Cancer (2013) ncbi
mouse monoclonal (AK7)
  • FC; human
In order to perform a phoshoproteomic analysis of the collagen receptor signalling network and study the importance of SHP-2 phosphorylation, AbD Serotec (Bio-Rad) integrin alpha2 antibody (AbD Serotec, AK7) was used in flow cytometry on human samples. Biochem J (2013) ncbi
mouse monoclonal (AK7)
  • Neut; human; 10 ug/ml
  • IC; human; 10 ug/ml
AbD Serotec (Bio-Rad) integrin alpha2 antibody (AbD Serotec, AK7) was used in neutralization on human samples at 10 ug/ml and in immunocytochemistry on human samples at 10 ug/ml. PLoS ONE (2012) ncbi
mouse monoclonal (16B4)
  • IHC-P; human
AbD Serotec (Bio-Rad) integrin alpha2 antibody (Serotec, MCA2025) was used in immunohistochemistry - paraffin section on human samples. Clin Exp Metastasis (2013) ncbi
mouse monoclonal (AK7) AbD Serotec (Bio-Rad) integrin alpha2 antibody (Serotec, MCA743) was used . J Biol Chem (2012) ncbi
Invitrogen
mouse monoclonal (AK7)
  • FC; human
In order to describe a method to expand antigen-specific regulatory T cells in vivo, Invitrogen integrin alpha2 antibody (Pierce, AK7) was used in flow cytometry on human samples. Nature (2016) ncbi
mouse monoclonal (31H4)
  • FC; human
In order to determine the function of alpha M beta-propeller in specific ligand recognition by alpha M beta 2, Invitrogen integrin alpha2 antibody (BIOSOURCE, 31H4) was used in flow cytometry on human samples. J Biol Chem (2003) ncbi
Abcam
mouse monoclonal (P1E6)
  • IP; human
In order to profile an integrin-mediated SV40 mechanism, Abcam integrin alpha2 antibody (Abcam, P1E6) was used in immunoprecipitation on human samples. PLoS ONE (2013) ncbi
BioLegend
not indicatedBiolegend APC-conjugated anti-CD49b antibody was used to perform cell sorting in order to study the role of Dectin-1 in anti-tumor responses.elife (2014) ncbi
BD Biosciences
mouse monoclonal (AK-7)
  • FC; human
BD Biosciences integrin alpha2 antibody (BD, AK-7) was used in flow cytometry on human samples. Clin Exp Metastasis (2013) ncbi
not indicated
  • WB; human
BD Biosciences monoclonal anti-integrin alpha 2 antibody was used as plasma membrane marker to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation.Mol Biol Cell (2009) ncbi
not indicated
  • FC; human
BD Pharmingen APC-conjugated anti-CD49b antibody was used in flow cytometry in order to study the role of CD31 (-) CD45 (-) side population (SP) cells in muscle regenerationAm J Pathol (2008) ncbi
Articles Reviewed
  1. Xavier Clemente-Casares et al. (2016). "Expanding antigen-specific regulatory networks to treat autoimmunity".PMID 26886799
  2. Seiji Mori et al. (2015). "Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells".PMID 26334633
  3. Chiara Pelillo et al. (2015). "Colorectal Cancer Metastases Settle in the Hepatic Microenvironment Through α5β1 Integrin".PMID 25857463
  4. Yi Chin Toh et al. (2015). "Modulation of integrin and E-cadherin-mediated adhesions to spatially control heterogeneity in human pluripotent stem cell differentiation".PMID 25736499
  5. Claudio Ricardo de Oliveira et al. (2015). "Effects of blocking αvβ3 integrin by a recombinant RGD disintegrin on remodeling of wound healing after induction of incisional hernia in rats".PMID 25714693
  6. Yang Shen et al. (2015). "Effect of surface chemistry on the integrin induced pathway in regulating vascular endothelial cells migration".PMID 25575348
  7. Shiho Chiba et al. (2014). "Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses".PMID 25149452
  8. Maciej J Stawikowski et al. (2014). "Glycosylation modulates melanoma cell α2β1 and α3β1 integrin interactions with type IV collagen".PMID 24958723
  9. Sònia Bassagañas et al. (2014). "Pancreatic cancer cell glycosylation regulates cell adhesion and invasion through the modulation of α2β1 integrin and E-cadherin function".PMID 24878505
  10. Christina M Termini et al. (2014). "The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density".PMID 24623721
  11. Joji Iida et al. (2014). "DNA aptamers against exon v10 of CD44 inhibit breast cancer cell migration".PMID 24586375
  12. Kiyoko Uehara et al. (2014). "Integrin αvβ5 in endothelial cells of rat splenic sinus: an immunohistochemical and ultrastructural study".PMID 24556923
  13. P Stampolidis et al. (2015). "LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody intervention".PMID 24362527
  14. Eui Seok Shin et al. (2014). "PEDF expression regulates the proangiogenic and proinflammatory phenotype of the lung endothelium".PMID 24318110
  15. F M Frame et al. (2013). "HDAC inhibitor confers radiosensitivity to prostate stem-like cells".PMID 24220693
  16. Patricia Costa et al. (2013). "Integrin-specific control of focal adhesion kinase and RhoA regulates membrane protrusion and invasion".PMID 24040310
  17. Leo K Iwai et al. (2013). "Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants".PMID 23822953
  18. L Damiano et al. (2014). "Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin".PMID 23770848
  19. Xiaodong Feng et al. (2013). "Fibrin and collagen differentially but synergistically regulate sprout angiogenesis of human dermal microvascular endothelial cells in 3-dimensional matrix".PMID 23737792
  20. D T Bridgen et al. (2013). "Integrin-mediated interactions with extracellular matrix proteins for nucleus pulposus cells of the human intervertebral disc".PMID 23737292
  21. Yi Ho et al. (2014). "Translucent titanium coating altered the composition of focal adhesions and promoted migration of osteoblast-like MG-63 cells on glass".PMID 23625870
  22. Kristina Kligys et al. (2013). "Laminin-332 and α3β1 integrin-supported migration of bronchial epithelial cells is modulated by fibronectin".PMID 23590307
  23. Daniel Ohlund et al. (2013). "Type IV collagen stimulates pancreatic cancer cell proliferation, migration, and inhibits apoptosis through an autocrine loop".PMID 23530721
  24. Piotr Jakubowski et al. (2013). "Identification of inhibitors of α2β1 integrin, members of C-lectin type proteins, in Echis sochureki venom".PMID 23499869
  25. Sucharitha Balasubramaniam et al. (2013). "Aberrant BAF57 signaling facilitates prometastatic phenotypes".PMID 23493350
  26. Lilli Stergiou et al. (2013). "Integrin-mediated signaling induced by simian virus 40 leads to transient uncoupling of cortical actin and the plasma membrane".PMID 23409046
  27. Huifang Xu et al. (2012). "Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activation".PMID 23284937
  28. Joseph L Sottnik et al. (2013). "Integrin alpha2beta 1 (α2β1) promotes prostate cancer skeletal metastasis".PMID 23242739
  29. Samir W Hamaia et al. (2012). "Mapping of potent and specific binding motifs, GLOGEN and GVOGEA, for integrin α1β1 using collagen toolkits II and III".PMID 22654115
  30. Zhongjian Xie et al. (2009). "Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation".PMID 19158393
  31. Norio Motohashi et al. (2008). "Muscle CD31(-) CD45(-) side population cells promote muscle regeneration by stimulating proliferation and migration of myoblasts".PMID 18669618
  32. Mario Vallon et al. (2006). "Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans".PMID 16982628
  33. Ilaria Cascone et al. (2005). "Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1".PMID 16157706
  34. Mi Sook Lee et al. (2005). "The signaling network of transforming growth factor beta1, protein kinase Cdelta, and integrin underlies the spreading and invasiveness of gastric carcinoma cells".PMID 16055706
  35. Kentaro Kajiya et al. (2005). "Hepatocyte growth factor promotes lymphatic vessel formation and function".PMID 16052207
  36. Faye Hui Chen et al. (2005). "Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins".PMID 16051604
  37. Lucia Gargiulo et al. (2005). "Cross-talk between fMLP and vitronectin receptors triggered by urokinase receptor-derived SRSRY peptide".PMID 15866865
  38. Ju Eun Oh et al. (2005). "Beta ig-h3 induces keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha3beta1 and the phosphatidylinositol 3-kinase/Akt signaling pathway".PMID 15805105
  39. Yang Li et al. (2003). "The fourth blade within the beta-propeller is involved specifically in C3bi recognition by integrin alpha M beta 2".PMID 12816955