This is a review about integrin alpha v, based on 21 published articles (read how Labome selects the articles), using integrin alpha v antibody in all methods. It is aimed to help Labome visitors find the most suited integrin alpha v antibody.
integrin alpha v synonym: CD51; MSK8; VNRA; VTNR; antigen identified by monoclonal antibody L230; integrin alpha-V; integrin alphaVbeta3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); vitronectin receptor subunit alpha

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Santa Cruz BiotechnologySanta Cruz Biotechnology integrin alpha v product
  • western blotIn 2005, Karim Kaabeche et al. employed Santa Cruz Biotechnology integrin alpha v antibody to study the functional link between FGFR2 signaling and Cbl-mediated alpha-5-integrin expression resulting in altered cell attachment and apoptosis in osteoblasts [ncbi , more ].
EMD MilliporeEMD Millipore integrin alpha v product
  • block or activateIn 2008, Sallouha Aidoudi et al. utilized EMD Millipore integrin alpha v antibody to perform blocking experiments and flow cytometry in order to show that integrins could interact with CXCL4 and play a role in angiogenesis [ncbi , more , fig ]. EMD Millipore integrin alpha v antibody was applied in 2005 to study the beta-ig-h3-mediated keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha-3, beta-1, and the phosphatidylinositol 3-kinase/Akt signaling pathway [ncbi , more ], to study the role of CAR, alphavbeta3 or alphavbeta5 integrin in PAd3 internalization [ncbi , more ], to study integrin-dependent NOV (CCN3) functions in wound healing [ncbi , more ]and to study the regulation of the endothelial cell response to Ang-1 through stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor [ncbi , more ]. In 2004, Shr Jeng Leu et al. utilized EMD Millipore integrin alpha v antibody to neutralize integrin alphavbeta3 in primary human foreskin fibroblasts [ncbi , more ]. Shr Jeng Leu et al. used EMD Millipore integrin alpha v antibody to identify a novel integrin alpha-6-beta-1 binding site in the angiogenic inducer CCN1 [ncbi , more ] in 2003 and Yang Li et al. used EMD Millipore integrin alpha v antibody to study the role of sequences within domain II of the urokinase receptor for differential ligand recognition [ncbi , more ]. In 2002, Gieri Camenisch et al. employed EMD Millipore integrin alpha v antibody to study the role for ANGPTL3 in endothelial cell adhesion and migration and blood vessel formation in Vivo in human cells [ncbi , more ]. In 2001, C C Chen et al. used EMD Millipore integrin alpha v antibody to study the induction of adhesive signaling in primary human skin fibroblasts [ncbi , more ].
  • flow cytometryIn 2010, Marta Irigoyen et al. employed EMD Millipore integrin alpha v antibody to perform flow cytometry in order to determine if this integrin influences TGFBI-mediated NSCLC cell susceptibility to chemotherapy [ncbi , more ]. In 2008, Sallouha Aidoudi et al. applied EMD Millipore integrin alpha v antibody to perform blocking experiments and flow cytometry in order to show that integrins could interact with CXCL4 and play a role in angiogenesis [ncbi , more , fig ].
  • immunocytochemistryIn 2009, Ramona Bhattacharya et al. applied EMD Millipore integrin alpha v antibody to carry out immunofluorescence assays in order to investigate the function for beta3 integrin-mediated vimentin IF recruitment to the cell surface [ncbi , more ]. In 2006, Jiansong Xie et al. utilized EMD Millipore integrin alpha v antibody to study the identity of the capsid proteins responsible for mediating Ad5 entry into the acinar epithelial cells of the lacrimal gland [ncbi , more ]. In 2005, Dinesh S Bangari et al. used EMD Millipore integrin alpha v antibody to study the role of CAR, alphavbeta3 or alphavbeta5 integrin in PAd3 internalization [ncbi , more ].
  • immunoprecipitationEMD Millipore integrin alpha v antibody was employed in 2005 to study the role of uPAR in cross-talk between FPR and alphavbeta5 [ncbi , more ], to study a sequence in domain 2 of uPAR that plays a structural and functional role in this interaction between the urokinase receptor (uPAR) and the integrin v 3 [ncbi , more ]and to study the regulation of the endothelial cell response to Ang-1 through stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor [ncbi , more ]. In 2004, Abha Sahni et al. applied EMD Millipore integrin alpha v antibody to study endothelial cell proliferation by FGF-2 [ncbi , more ]. In 2003, Shr Jeng Leu et al. used EMD Millipore integrin alpha v antibody to identify a novel integrin alpha-6-beta-1 binding site in the angiogenic inducer CCN1 [ncbi , more ].
  • western blotIn 2006, Mario Vallon et al. applied EMD Millipore integrin alpha v antibody to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells [ncbi , more ]. In 2004, Abha Sahni et al. applied EMD Millipore integrin alpha v antibody to study endothelial cell proliferation by FGF-2 [ncbi , more ]. In 2003, Qi Shi et al. utilized EMD Millipore integrin alpha v antibody to study the role for tethering-induced signaling mode for alpha5beta1 integrin in phosphorylation of FAK Y397 [ncbi , more ].
Sigma-AldrichSigma-Aldrich integrin alpha v product
  • block or activateIn 2004, Cheng Chi Chang et al. employed Sigma-Aldrich integrin alpha v antibody to study the role of connective tissue growth factor in lung adenocarcinoma invasion and metastasis [ncbi , more ].
EBERHARD KLEIN
  • immunohistochemistryIn 2004, Dirk Breitkreutz et al. applied integrin alpha v antibody to study basement membrane formation inhibition in human skin-organotypic cocultures [ncbi , more ].
Figure
Chemicon monoclonal anti-alphavbeta5 was used to perform blocking experiments and flow cytometry in order to show that integrins could interact with CXCL4 and play a role in angiogenesis.
integrin alpha v antibody flow cytometry EMD Millipore
Expression profile of integrins in HUVECs cells analyzed by flow cytometry. HUVECs were incubated with primary antibodies specific for alphavbeta3 (LM609), or alphavbeta5 (P1F6), or alpha5beta1 (HA5) and antibody binding was detected with FITC-labeled secondary antibody. Cells stained with secondary antibody (2 Ab) only were used as a negative control.
integrin alpha v antibody block or activate EMD Millipore
Cell adhesion to CXCL4 and CXCL4/CTF is alphavbeta3, alphavbeta5 and alpha5beta1 integrins dependent. Cells were incubated with the indicated antibodies or RGD-, RGE peptides before plating to wells coated with CXCL4 or CXCL4/CTF. Anti-integrin antibodies used were: anti-alphavbeta3 (LM609), anti-alphav (ALPHAV1), anti-beta3 (B3A), anti-alphavbeta5 (P1F6), anti-alpha5beta1 (JBS5), anti-alpha5 (P1D6) and anti-beta1 (CD29).
Sallouha Aidoudi et al. (2008). "The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis".PMID 18648521
Articles Reviewed
  1. Marta Irigoyen et al. (2010). "TGFBI expression is associated with a better response to chemotherapy in NSCLC".PMID 20509890
  2. Ramona Bhattacharya et al. (2009). "Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength".PMID 19366731
  3. Sallouha Aidoudi et al. (2008). "The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis".PMID 18648521
  4. Jiansong Xie et al. (2006). "Novel fiber-dependent entry mechanism for adenovirus serotype 5 in lacrimal acini".PMID 16987972
  5. Mario Vallon et al. (2006). "Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans".PMID 16982628
  6. Ilaria Cascone et al. (2005). "Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1".PMID 16157706
  7. Lucia Gargiulo et al. (2005). "Cross-talk between fMLP and vitronectin receptors triggered by urokinase receptor-derived SRSRY peptide".PMID 15866865
  8. Bernard Degryse et al. (2005). "Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor".PMID 15863511
  9. Ju Eun Oh et al. (2005). "Beta ig-h3 induces keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha3beta1 and the phosphatidylinositol 3-kinase/Akt signaling pathway".PMID 15805105
  10. Karim Kaabeche et al. (2005). "Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation".PMID 15728256
  11. Dinesh S Bangari et al. (2005). "Porcine adenovirus serotype 3 internalization is independent of CAR and alphavbeta3 or alphavbeta5 integrin".PMID 15661148
  12. Cristiane G Lin et al. (2005). "Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing".PMID 15611078
  13. Shr Jeng Leu et al. (2004). "Targeted mutagenesis of the angiogenic protein CCN1 (CYR61). Selective inactivation of integrin alpha6beta1-heparan sulfate proteoglycan coreceptor-mediated cellular functions".PMID 15322081
  14. Abha Sahni et al. (2004). "Stimulation of endothelial cell proliferation by FGF-2 in the presence of fibrinogen requires alphavbeta3".PMID 15297314
  15. Dirk Breitkreutz et al. (2004). "Inhibition of basement membrane formation by a nidogen-binding laminin gamma1-chain fragment in human skin-organotypic cocultures".PMID 15159456
  16. Cheng Chi Chang et al. (2004). "Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis".PMID 14996858
  17. Qi Shi et al. (2003). "A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAK Y397".PMID 12960434
  18. Shr Jeng Leu et al. (2003). "Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61)".PMID 12826661
  19. Yang Li et al. (2003). "Sequences within domain II of the urokinase receptor critical for differential ligand recognition".PMID 12761227
  20. Gieri Camenisch et al. (2002). "ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo".PMID 11877390
  21. C C Chen et al. (2001). "The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts".PMID 11120741