This is a review about alpha synuclein, based on 24 published articles (read how Labome selects the articles), using alpha synuclein antibody in experiments. It is aimed to help Labome visitors find the most suited alpha synuclein antibody.
alpha synuclein synonym: NACP; PARK1; PARK4; PD1; alpha-synuclein; non A-beta component of AD amyloid; synuclein alpha-140

  • Santa Cruz Biotechnology anti-alpha-syn mAb211 antibody was used to perform western blot in order to develop a cell modle of LB-associated neurodegeneration. (catalog: sc-12767) ncbi, more
  • suppliernumreagent linkcited catalog
    Life Technologies Corporation5alpha synuclein antibody
    EMD Millipore3alpha synuclein antibodyAB5038P
    Synaptic Systems1
    Santa Cruz Biotechnology1alpha synuclein antibodysc-12767
    BD Biosciences11610786
    Meridian Life Science1
    Wako Chemicals USA1
    Table 1. alpha synuclein antibody western blot.
  • Santa Cruz Biotechnology goat polyclonal antibody directed against amino acids 1 to 19 of alpha-synuclein was used in immunocytochemistry to detect alpha-synuclein in substantia nigra and hippocampal tissues from five patients with a pathological diagnosis of DLBD and five control cases (catalog: SC-7012) ncbi, more
  • Chemicon anti-alpha-syn Ab111 antibody was used to perform western blot in order to develop a cell modle of LB-associated neurodegeneration. (catalog: AB5038P) ncbi, more
  • Chemicon international anti-alpha-syn AB5464 antibody was used to perform western blot in order to develop a cell modle of LB-associated neurodegeneration.ncbi, more
  • Chemicon rabbit polyclonal anti-alpha-synuclein antibody was used in paraffin sections from human brain tissues and in immunohistochemistry to study the role of tTGase in the formation of alpha-synuclein aggregates.ncbi, more
  • Chemicon rabbit anti-alpha-synuclein polyclonal antibody was used in western blot and immunocytochemistry to study the parkin accumulation in aggresomes due to proteasome impairment.ncbi, more
  • suppliernumreagent link
    Life Technologies Corporation5alpha synuclein antibody
    EMD Millipore1alpha synuclein antibody
    Meridian Life Science1
    Dako1
    Covance1
    Table 2. alpha synuclein antibody immunohistochemistry.
  • StressGen anti-PD1 antibody was used in immunocytochemistry to study DISC1 localizationncbi, more
  • Zymed monoclonal alpha-synuclein antibody was used for immunohistochemistry in order to study the function of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases.ncbi, more
  • Zymed SNCA antibody was used in immunohistochemistry to examine LBP in the brainstem, limbic cortex, and neocortex of a large number of familial AD cases with mutations in 2 presenilin (PSEN) genes.ncbi, more
  • Zymed alpha-synuclein (LB509) antibody was used in immunohistochemistry to study the regulation of tau ubiquitination, degradation, and aggregation by CHIP and Hsp70ncbi, more
  • Zymed monoclonal anti-alpha-synuclein antibody LB509 was used in human embryonic kidney (HEK) 293T cells and in immunoprecipitation, western blot to study the role of tTGase in the formation of alpha-synuclein aggregates.ncbi, more
  • suppliernumreagent linkcited catalog
    Enzo Life Sciences1alpha synuclein antibody
    EMD Millipore1alpha synuclein antibody
    Life Technologies Corporation1alpha synuclein antibody
    Santa Cruz Biotechnology1alpha synuclein antibodySC-7012
    BD Biosciences3
    Sigma-Aldrich1
    Table 3. alpha synuclein antibody immunocytochemistry.
  • Zymed Laboratories monoclonal anti-alpha-synuclein antibody LB509 was used in African monkey kidney cell line COS-7 with human alpha-synuclein and in immunocytochemistry, western blot to study the mechanism of alpha-synuclein aggregation in cells.ncbi, more
  • Zymed anti-alpha-synuclein antibody was used in immunohistochemistry and western blot to study the Localization of parkin to the lewy bodies of parkinson disease and dementia with lewy bodies.ncbi, more
  • Zymed Laboratories Inc. anti-alpha-syn antibody LB509 was used in african monkey kidney cell line COS-7 with human wild type alpha-syn cDNA and in western blot to study the effects of inhibitors of the mitochondrial electron-transport chain on the aggregation of synuclein.ncbi, more
  • Zymed mouse monoclonal anti-alpha-synuclein antibody (LB509) was used in western blot and immunohistochemistry to study inhibition of alpha-synuclein aggregation by beta-synuclein.ncbi, more
Synaptic Systems
  • Synaptic System GmbH anti-alpha-syn SYN128 antibody was used to perform western blot in order to develop a cell modle of LB-associated neurodegeneration.ncbi, more
  • suppliernumreagent link
    Life Technologies Corporation1alpha synuclein antibody
    BD Biosciences3
    Table 4. alpha synuclein antibody immunoprecipitation.
BD Biosciences
  • BD anti-synuclein-1 antibody was used to perform western blot and immonocytochemistry in order to develop a cell modle of LB-associated neurodegeneration.ncbi, more
  • BD Transduction monoclonal anti-alpha-synuclein antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. (catalog: 610786) ncbi, more
  • BD-Transduction Labs alpha-Syn antibody was used in western blot in order to study the function of the PD-related protein alpha-synuclein (alpha-Syn) with regard to dopamine synthesisncbi, more
  • Pharmingen anti-alpha-synuclein antibody was used in western blot to detect alpha-synuclein in HEK293 cells co-transfected with His-SUMO isoforms (SUMO1, SUMO2, and SUMO3) and full-length human tau or alpha-synuclein.ncbi, more
  • Transduction Laboratory mouse alpha-synuclein antibody was used in western blot and immunocytochemistry to study the effect of DJ-1 on alpha-synuclein toxicityncbi, more
  • suppliernum
    Meridian Life Science1
    Table 5. alpha synuclein antibody ELISA.
  • BD Biosciences anti-alpha-synuclein antibody was used in western blot to study the role of glycogen synthase kinase 3 beta on synphilin-1 ubiquitylationncbi, more
  • BD Transduction Laboratory anti-alpha-synuclein antibody was used in western blot and immunocytochemistry to the proteolytic cleavage of extracellularly secreted alpha-synuclein via the activation of MMP-3 in a selective manner.ncbi, more
  • Transduction Labs anti-alpha-synuclein antibody was used in western blot and immunoprecipitation to study the role of alpha-, beta-, and gamma-synuclein in regulating proteasomal function.ncbi, more
  • Transduction Laboratories monoclonal anti-alpha-synuclein antibody SYN-1 was used in human embryonic kidney (HEK) 293T cells and in immunoprecipitation, western blot to study the role of tTGase in the formation of alpha-synuclein aggregates.ncbi, more
  • Transduction Labs anti-syn-1 antibody was used in western blot to study the Localization of parkin to the lewy bodies of parkinson disease and dementia with lewy bodies.ncbi, more
  • Transduction Laboratories mouse anti-alpha-synuclein (Syn-1) antibody was used in western blot and immunoprecipitation to study the role for alpha-synuclein in the regulation of dopamine biosynthesis.ncbi, more
Sigma-Aldrich
  • Sigma rabbit polyclonal anti-alpha-synuclein antibody was used in human embryonic kidney (HEK) 293T cells and in immunocytochemistry to study the role of tTGase in the formation of alpha-synuclein aggregates.ncbi, more
Meridian Life Science
  • Biodesign International polyclonal goat anti-alpha-synuclein antibody was used in western blot, ELISA, and immunohistochemistry to study the role for the interaction of agrin with alpha-synuclein in modulating alpha-synuclein fibrillation in tissue and paraffin sections from PD patients brain.ncbi, more
Dako
  • Dako anti-alpha-synuclein (SNCA) antibody was used in immunohistochemistry to study whether PGRN genetic variability contributed to other common neurodegenerative brain diseases, such as Alzheimer disease (AD) or Parkinson disease (PD) in sections from human.ncbi, more
JQ TROJANOWSKI
  • Dr. J.Q. Trojanowski alpha-synuclein antibody was used in western blot and immunohistochemistry (LB509, 1 : 1 : 1000 and syn 303, 1 : 500) to study a novel progranulin mutation associated with variable clinical presentation and tau, TDP43, and alpha-synuclein pathologyncbi, more
Covance
  • Signet anti-alpha-synuclein antibody was used for western blot to elucidated the role of white matter tauopathy in frontotemporal lobar degeneration.ncbi, more
Wako Chemicals USA
  • Wako Chemicals anti- alpha-syn phosphorylation antibody was used to perform western blot in order to develop a cell modle of LB-associated neurodegeneration.ncbi, more
Articles Reviewed
  1. Jacqueline Burré et al. (2010). "Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro".PMID 20798282
  2. Li wen Ko et al. (2008). "Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells".PMID 18957893
  3. Gabor G Kovacs et al. (2008). "White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration".PMID 18800011
  4. Wen Lang Lin et al. (2008). "Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases".PMID 18607609
  5. Tshianda N M Alerte et al. (2008). "Alpha-synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity: lessons from viral transduction of knockout mice".PMID 18314273
  6. Nathalie Brouwers et al. (2007). "Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family".PMID 17923627
  7. J B Leverenz et al. (2007). "A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology".PMID 17439980
  8. James B Leverenz et al. (2006). "Lewy body pathology in familial Alzheimer disease: evidence for disease- and mutation-specific pathologic phenotype".PMID 16533963
  9. Veronique Dorval et al. (2006). "Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein".PMID 16464864
  10. Wenbo Zhou et al. (2005). "DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity".PMID 16227205
  11. Eyal Avraham et al. (2005). "Glycogen synthase kinase 3beta modulates synphilin-1 ubiquitylation and cellular inclusion formation by SIAH: implications for proteasomal function and Lewy body formation".PMID 16174773
  12. I Hsuan Liu et al. (2005). "Agrin binds alpha-synuclein and modulates alpha-synuclein fibrillation".PMID 16037493
  13. Jee Young Sung et al. (2005). "Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases".PMID 15863497
  14. Heather Snyder et al. (2005). "beta-Synuclein reduces proteasomal inhibition by alpha-synuclein but not gamma-synuclein".PMID 15591046
  15. Leonard Petrucelli et al. (2004). "CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation".PMID 14962978
  16. Jill A Morris et al. (2003). "DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation".PMID 12812986
  17. Eunsung Junn et al. (2003). "Tissue transglutaminase-induced aggregation of alpha-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies".PMID 12576551
  18. Eunsung Junn et al. (2002). "Parkin accumulation in aggresomes due to proteasome impairment".PMID 12364339
  19. He Jin Lee et al. (2002). "Characterization of cytoplasmic alpha-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells".PMID 12351642
  20. Michael G Schlossmacher et al. (2002). "Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies".PMID 12000718
  21. Ruth G Perez et al. (2002). "A role for alpha-synuclein in the regulation of dopamine biosynthesis".PMID 11943812
  22. He Jin Lee et al. (2002). "Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors".PMID 11724769
  23. M Hashimoto et al. (2001). "beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor".PMID 11683992
  24. N Sharma et al. (2001). "A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study".PMID 11438481