This is a review about alpha synuclein, based on 24 published articles (read how Labome selects the articles), using alpha synuclein antibody in all methods. It is aimed to help Labome visitors find the most suited alpha synuclein antibody.
alpha synuclein synonym: NACP; PARK1; PARK4; PD1; alpha-synuclein; non A-beta component of AD amyloid; synuclein alpha-140

Santa Cruz BiotechnologySanta Cruz Biotechnology alpha synuclein product
  • immunocytochemistryIn 2001, N Sharma et al. applied Santa Cruz Biotechnology alpha synuclein antibody to detect alpha-synuclein in substantia nigra and hippocampal tissues from five patients with a pathological diagnosis of DLBD and five control cases (catalog: SC-7012) [ncbi , more ].
  • western blotIn 2008, Li wen Ko et al. applied Santa Cruz Biotechnology alpha synuclein antibody to perform western blot in order to develop a cell modle of LB-associated neurodegeneration (catalog: sc-12767) [ncbi , more ].
EMD MilliporeEMD Millipore alpha synuclein product
  • immunocytochemistryIn 2002, Eunsung Junn et al. used EMD Millipore alpha synuclein antibody to study the parkin accumulation in aggresomes due to proteasome impairment [ncbi , more ].
  • immunohistochemistryIn 2003, Eunsung Junn et al. employed EMD Millipore alpha synuclein antibody to study the role of tTGase in the formation of alpha-synuclein aggregates [ncbi , more ].
  • western blotIn 2008, Li wen Ko et al. employed EMD Millipore alpha synuclein antibody to perform western blot in order to develop a cell modle of LB-associated neurodegeneration (catalog: AB5038P) [ncbi , more ]. In 2002, Eunsung Junn et al. used EMD Millipore alpha synuclein antibody to study the parkin accumulation in aggresomes due to proteasome impairment [ncbi , more ].
Enzo Life SciencesEnzo Life Sciences alpha synuclein product
  • immunocytochemistryIn 2003, Jill A Morris et al. employed Enzo Life Sciences alpha synuclein antibody to study DISC1 localization [ncbi , more ].
Life Technologies CorporationLife Technologies Corporation alpha synuclein product
  • immunocytochemistryIn 2002, He Jin Lee et al. employed Life Technologies Corporation alpha synuclein antibody to study the mechanism of alpha-synuclein aggregation in cells [ncbi , more ].
  • immunohistochemistryIn 2008, Wen Lang Lin et al. utilized Life Technologies Corporation alpha synuclein antibody to study the function of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases [ncbi , more ]. In 2006, James B Leverenz et al. utilized Life Technologies Corporation alpha synuclein antibody to examine LBP in the brainstem, limbic cortex, and neocortex of a large number of familial AD cases with mutations in 2 presenilin (PSEN) genes [ncbi , more ]. In 2004, Leonard Petrucelli et al. employed Life Technologies Corporation alpha synuclein antibody to study the regulation of tau ubiquitination, degradation, and aggregation by CHIP and Hsp70 [ncbi , more ]. In 2002, Michael G Schlossmacher et al. applied Life Technologies Corporation alpha synuclein antibody to study the Localization of parkin to the lewy bodies of parkinson disease and dementia with lewy bodies [ncbi , more ]. In 2001, M Hashimoto et al. used Life Technologies Corporation alpha synuclein antibody to study inhibition of alpha-synuclein aggregation by beta-synuclein [ncbi , more ].
  • immunoprecipitationIn 2003, Eunsung Junn et al. employed Life Technologies Corporation alpha synuclein antibody to study the role of tTGase in the formation of alpha-synuclein aggregates [ncbi , more ].
  • western blotIn 2003, Eunsung Junn et al. employed Life Technologies Corporation alpha synuclein antibody to study the role of tTGase in the formation of alpha-synuclein aggregates [ncbi , more ]. Life Technologies Corporation alpha synuclein antibody was used in 2002 to study the Localization of parkin to the lewy bodies of parkinson disease and dementia with lewy bodies [ncbi , more ], to study the effects of inhibitors of the mitochondrial electron-transport chain on the aggregation of synuclein [ncbi , more ]and to study the mechanism of alpha-synuclein aggregation in cells [ncbi , more ]. In 2001, M Hashimoto et al. used Life Technologies Corporation alpha synuclein antibody to study inhibition of alpha-synuclein aggregation by beta-synuclein [ncbi , more ].
Synaptic Systems
  • western blotIn 2008, Li wen Ko et al. applied Synaptic Systems alpha synuclein antibody to perform western blot in order to develop a cell modle of LB-associated neurodegeneration [ncbi , more ].
BD Biosciences
  • immunocytochemistryIn 2008, Li wen Ko et al. applied BD Biosciences alpha synuclein antibody to perform western blot and immonocytochemistry in order to develop a cell modle of LB-associated neurodegeneration [ncbi , more ]. Wenbo Zhou et al. employed BD Biosciences alpha synuclein antibody to study the effect of DJ-1 on alpha-synuclein toxicity [ncbi , more ] in 2005 and Jee Young Sung et al. used BD Biosciences alpha synuclein antibody to the proteolytic cleavage of extracellularly secreted alpha-synuclein via the activation of MMP-3 in a selective manner [ncbi , more ].
  • immunoprecipitationIn 2005, Heather Snyder et al. used BD Biosciences alpha synuclein antibody to study the role of alpha-, beta-, and gamma-synuclein in regulating proteasomal function [ncbi , more ]. In 2003, Eunsung Junn et al. employed BD Biosciences alpha synuclein antibody to study the role of tTGase in the formation of alpha-synuclein aggregates [ncbi , more ]. In 2002, Ruth G Perez et al. used BD Biosciences alpha synuclein antibody to study the role for alpha-synuclein in the regulation of dopamine biosynthesis [ncbi , more ].
  • western blotIn 2010, Jacqueline BurrĂ© et al. applied BD Biosciences alpha synuclein antibody to carry out western blot analysis in order to determine the atomic structure of human adenovirus (catalog: 610786) [ncbi , more ]. Li wen Ko et al. applied BD Biosciences alpha synuclein antibody to perform western blot and immonocytochemistry in order to develop a cell modle of LB-associated neurodegeneration [ncbi , more ] in 2008 and Tshianda N M Alerte et al. used BD Biosciences alpha synuclein antibody to study the function of the PD-related protein alpha-synuclein (alpha-Syn) with regard to dopamine synthesis [ncbi , more ]. In 2006, Veronique Dorval et al. employed BD Biosciences alpha synuclein antibody to detect alpha-synuclein in HEK293 cells co-transfected with His-SUMO isoforms (SUMO1, SUMO2, and SUMO3) and full-length human tau or alpha-synuclein [ncbi , more ]. BD Biosciences alpha synuclein antibody was used in 2005 to study the role of glycogen synthase kinase 3 beta on synphilin-1 ubiquitylation [ncbi , more ], to the proteolytic cleavage of extracellularly secreted alpha-synuclein via the activation of MMP-3 in a selective manner [ncbi , more ], to study the role of alpha-, beta-, and gamma-synuclein in regulating proteasomal function [ncbi , more ]and to study the effect of DJ-1 on alpha-synuclein toxicity [ncbi , more ]. In 2003, Eunsung Junn et al. employed BD Biosciences alpha synuclein antibody to study the role of tTGase in the formation of alpha-synuclein aggregates [ncbi , more ]. Michael G Schlossmacher et al. applied BD Biosciences alpha synuclein antibody to study the Localization of parkin to the lewy bodies of parkinson disease and dementia with lewy bodies [ncbi , more ] in 2002 and Ruth G Perez et al. used BD Biosciences alpha synuclein antibody to study the role for alpha-synuclein in the regulation of dopamine biosynthesis [ncbi , more ].
Sigma-AldrichSigma-Aldrich alpha synuclein product
  • immunocytochemistryIn 2003, Eunsung Junn et al. employed Sigma-Aldrich alpha synuclein antibody to study the role of tTGase in the formation of alpha-synuclein aggregates [ncbi , more ].
Meridian Life Science
  • ELISAIn 2005, I Hsuan Liu et al. applied Meridian Life Science alpha synuclein antibody to study the role for the interaction of agrin with alpha-synuclein in modulating alpha-synuclein fibrillation in tissue and paraffin sections from PD patients brain [ncbi , more ].
  • immunohistochemistryIn 2005, I Hsuan Liu et al. applied Meridian Life Science alpha synuclein antibody to study the role for the interaction of agrin with alpha-synuclein in modulating alpha-synuclein fibrillation in tissue and paraffin sections from PD patients brain [ncbi , more ].
  • western blotIn 2005, I Hsuan Liu et al. applied Meridian Life Science alpha synuclein antibody to study the role for the interaction of agrin with alpha-synuclein in modulating alpha-synuclein fibrillation in tissue and paraffin sections from PD patients brain [ncbi , more ].
Dako
  • immunohistochemistryIn 2007, Nathalie Brouwers et al. applied Dako alpha synuclein antibody to study whether PGRN genetic variability contributed to other common neurodegenerative brain diseases, such as Alzheimer disease (AD) or Parkinson disease (PD) in sections from human [ncbi , more ].
JQ TROJANOWSKI
  • immunohistochemistryIn 2007, J B Leverenz et al. employed alpha synuclein antibody to study a novel progranulin mutation associated with variable clinical presentation and tau, TDP43, and alpha-synuclein pathology [ncbi , more ].
Covance
  • immunohistochemistryIn 2008, Gabor G Kovacs et al. used Covance alpha synuclein antibody to elucidated the role of white matter tauopathy in frontotemporal lobar degeneration [ncbi , more ].
Wako Chemicals USA
  • western blotIn 2008, Li wen Ko et al. applied Wako Chemicals USA alpha synuclein antibody to perform western blot in order to develop a cell modle of LB-associated neurodegeneration [ncbi , more ].
Articles Reviewed
  1. Jacqueline Burré et al. (2010). "Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro".PMID 20798282
  2. Li wen Ko et al. (2008). "Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells".PMID 18957893
  3. Gabor G Kovacs et al. (2008). "White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration".PMID 18800011
  4. Wen Lang Lin et al. (2008). "Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases".PMID 18607609
  5. Tshianda N M Alerte et al. (2008). "Alpha-synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity: lessons from viral transduction of knockout mice".PMID 18314273
  6. Nathalie Brouwers et al. (2007). "Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family".PMID 17923627
  7. J B Leverenz et al. (2007). "A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology".PMID 17439980
  8. James B Leverenz et al. (2006). "Lewy body pathology in familial Alzheimer disease: evidence for disease- and mutation-specific pathologic phenotype".PMID 16533963
  9. Veronique Dorval et al. (2006). "Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein".PMID 16464864
  10. Wenbo Zhou et al. (2005). "DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity".PMID 16227205
  11. Eyal Avraham et al. (2005). "Glycogen synthase kinase 3beta modulates synphilin-1 ubiquitylation and cellular inclusion formation by SIAH: implications for proteasomal function and Lewy body formation".PMID 16174773
  12. I Hsuan Liu et al. (2005). "Agrin binds alpha-synuclein and modulates alpha-synuclein fibrillation".PMID 16037493
  13. Jee Young Sung et al. (2005). "Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases".PMID 15863497
  14. Heather Snyder et al. (2005). "beta-Synuclein reduces proteasomal inhibition by alpha-synuclein but not gamma-synuclein".PMID 15591046
  15. Leonard Petrucelli et al. (2004). "CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation".PMID 14962978
  16. Jill A Morris et al. (2003). "DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation".PMID 12812986
  17. Eunsung Junn et al. (2003). "Tissue transglutaminase-induced aggregation of alpha-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies".PMID 12576551
  18. Eunsung Junn et al. (2002). "Parkin accumulation in aggresomes due to proteasome impairment".PMID 12364339
  19. He Jin Lee et al. (2002). "Characterization of cytoplasmic alpha-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells".PMID 12351642
  20. Michael G Schlossmacher et al. (2002). "Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies".PMID 12000718
  21. Ruth G Perez et al. (2002). "A role for alpha-synuclein in the regulation of dopamine biosynthesis".PMID 11943812
  22. He Jin Lee et al. (2002). "Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors".PMID 11724769
  23. M Hashimoto et al. (2001). "beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor".PMID 11683992
  24. N Sharma et al. (2001). "A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study".PMID 11438481