This is a review about WRN, based on 10 published articles (read how Labome selects the articles), using WRN antibody in experiments. It is aimed to help Labome visitors find the most suited WRN antibody.
WRN synonym: RECQ3; RECQL2; RECQL3; DNA helicase, RecQ-like type 3; Werner syndrome ATP-dependent helicase; exonuclease WRN; recQ protein-like 2

  • Abcam anti-WRN (ab200) antibody was used in western blot and immunoprecipitation to study the interaction between WRN and recombination mediator protein RAD52 (catalog: ab200) ncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology3WRN antibodySC-5629
    Novus Biologicals1
    Abcam1WRN antibodyab200
    BD Biosciences5
    Table 1. WRN antibody western blot.
Santa Cruz BiotechnologySanta Cruz Biotechnology WRN product
  • Santa Cruz Biotechnology anti-WRN polyclonal antibody (SC-5629) was used in western blot and immunoprecipitation to study polymerase beta strand displacement synthesis stimulated by WRN (catalog: SC-5629) ncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal anti-WRN antibody H-300 was used in human glioma cell line MO59-K, human lymphoblastoid lines K562, and Jurkat and in western blot and immunoprecipitation to study the effect of DNA damage on nucleolar interaction of the werner protein with the AAA ATPase p97/VCP.ncbi, more
  • Santa Cruz Biotechnology goat polyclonal anti-WRN antibody was used in immunoprecipitation to study the interaction of human exonuclease 1 with the carboxyl-terminal region of the Werner syndrome protein which stimulates the exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1.ncbi, more
  • Santa Cruz antibody against WRN was used in western blot to study the regulational role for p53 in the processing of holliday junctions by BLM and WRN helicases.ncbi, more
Novus Biologicals
  • Novus Santa anti-WRN antibody (SC-5629) was used in ELISA to study polymerase beta strand displacement synthesis stimulated by WRNncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology3WRN antibodySC-5629
    Novus Biologicals1
    Abcam1WRN antibodyab200
    Table 2. WRN antibody immunoprecipitation.
  • Novusbio polyclonal WRN antibody was used in ELISA to investiget the interaction of POT1 with WRN and BLM.ncbi, more
  • Novus Biological anti-Wrn was used in immunocytochemistry to stain for Wrn localization in HeLa cells.ncbi, more
  • Novus rabbit anti-WRN1 antibody was used in human glioma cell line MO59-K, human lymphoblastoid lines K562 and Jurkat and in immunoprecipitation to study the effect of DNA damage on nucleolar interaction of the werner protein with the AAA ATPase p97/VCP.ncbi, more
  • Novus rabbit anti-WRN polyclonal antibody was used in western blot to colocalize Werner and Bloom syndrome proteins and study their physical and functional interaction.ncbi, more
BD Biosciences
  • Transduction Laboratories anti-WRN antibody was used to carry out western blot analysis in order to investigate the role for WRN in ATM pathway activation and the S-phase checkpoint in cells exposed to DNA interstrand cross-link-induced double-strand breaks.ncbi, more
  • suppliernum
    Novus Biologicals2
    Table 3. WRN antibody ELISA.
  • BD Transduction Laboratories mouse monoclonal anti-WRNp antibody was used in human glioma cell line MO59-K and in western blot, immunocytochemistry to study the effect of DNA damage on nucleolar interaction of the werner protein with the AAA ATPase p97/VCP.ncbi, more
  • BD Pharmingen mouse monoclonal anti-WRN antibody was used in western blot to study the interaction of human exonuclease 1 with the carboxyl-terminal region of the Werner syndrome protein which stimulates the exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1.ncbi, more
  • Transduction Laboratories mouse anti-WRN antibody was used in western blot to detect the association of TRF2 with WRN in HeLa cells.ncbi, more
  • Becton Dickinson mouse anti-WRN antibody was used in western blot to colocalize Werner and Bloom syndrome proteins and study their physical and functional interaction.ncbi, more
suppliernum
Novus Biologicals1
BD Biosciences1
Table 4. WRN antibody immunocytochemistry.
Articles Reviewed
  1. Wen Hsing Cheng et al. (2008). "WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks".PMID 18596239
  2. Patricia L Opresko et al. (2005). "POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates".PMID 16030011
  3. Jacob G Robison et al. (2004). "Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks".PMID 15180989
  4. Juneth Joaquin Partridge et al. (2003). "DNA damage modulates nucleolar interaction of the Werner protein with the AAA ATPase p97/VCP".PMID 12937274
  5. Sudha Sharma et al. (2003). "The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein".PMID 12704184
  6. Jeanine A Harrigan et al. (2003). "The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity".PMID 12665521
  7. Kimberly A Huebsch et al. (2003). "Rapsyn-mediated clustering of acetylcholine receptor subunits requires the major cytoplasmic loop of the receptor subunits".PMID 12532399
  8. Patricia L Opresko et al. (2002). "Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases".PMID 12181313
  9. Qin Yang et al. (2002). "The processing of Holliday junctions by BLM and WRN helicases is regulated by p53".PMID 12080066
  10. Cayetano Von Kobbe et al. (2002). "Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins".PMID 11919194