This is a review about WRN, based on 3 published articles (read how Labome selects the articles), using WRN antibody in all methods. It is aimed to help Labome visitors find the most suited WRN antibody.
WRN synonym: RECQ3; RECQL2; RECQL3; DNA helicase, RecQ-like type 3; Werner syndrome, RecQ helicase-like; exonuclease WRN; recQ protein-like 2

Novus Biologicals
rabbit polyclonal
  • WB (knockdown); human; 1:1000; fig 5
In order to identify a novel DNA2- and WRN-dependent mechanism of reversed replication fork processing and restart after prolonged genotoxic stress, Novus Biologicals WRN antibody (Novus, NB100-471) was used in western blot (knockdown) on human samples at 1:1000 (fig 5). J Cell Biol (2015) ncbi
not indicated
  • ELISA; human
Novusbio polyclonal WRN antibody was used in ELISA to investiget the interaction of POT1 with WRN and BLM.J Biol Chem (2005) ncbi
BD Biosciences
not indicated
  • WB; human
Transduction Laboratories anti-WRN antibody was used to carry out western blot analysis in order to investigate the role for WRN in ATM pathway activation and the S-phase checkpoint in cells exposed to DNA interstrand cross-link-induced double-strand breaks.Mol Biol Cell (2008) ncbi
Articles Reviewed
  1. Saravanabhavan Thangavel et al. (2015). "DNA2 drives processing and restart of reversed replication forks in human cells".PMID 25733713
  2. Wen Hsing Cheng et al. (2008). "WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks".PMID 18596239
  3. Patricia L Opresko et al. (2005). "POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates".PMID 16030011