This is a review about TNFR2, based on 22 published articles (read how Labome selects the articles), using TNFR2 antibody in all methods. It is aimed to help Labome visitors find the most suited TNFR2 antibody.
TNFR2 synonym: CD120b; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; p75; p75TNFR; TNF-R2; TNF-RII; p75 TNF receptor; p80 TNF-alpha receptor; soluble TNFR1B variant 1; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; tumor necrosis factor receptor 2; tumor necrosis factor receptor superfamily, member 1B; tumor necrosis factor receptor type II

Knockout validation
Santa Cruz Biotechnologygoat polyclonal (L-20)
  • IC (knockout); mouse; 1:400; fig 1
Santa Cruz Biotechnology TNFR2 antibody (Santa, sc-1074) was used in immunocytochemistry (knockout) on mouse samples at 1:400 (fig 1). FASEB J (2012) ncbi
Santa Cruz Biotechnology
goat polyclonal (L-20)
  • WB; human
Santa Cruz Biotechnology TNFR2 antibody (Santa Cruz Biotechnologies, sc-1074) was used in western blot on human samples. PLoS ONE (2015) ncbi
rabbit polyclonal (H-202)
  • IHC-P; mouse
Santa Cruz Biotechnology TNFR2 antibody (Santa Cruz Biotechnology, sc-7862) was used in immunohistochemistry - paraffin section on mouse samples. Nephron Extra (2015) ncbi
goat polyclonal (C-20)
  • WB; Domestic guinea pig; 1:100
Santa Cruz Biotechnology TNFR2 antibody (Santa Cruz Biotechnology, sc-1072) was used in western blot on Domestic guinea pig samples at 1:100. Theriogenology (2015) ncbi
rabbit polyclonal (H-202)
  • IP; mouse
Santa Cruz Biotechnology TNFR2 antibody (Santa Cruz Biotechnology, SC-7862) was used in immunoprecipitation on mouse samples. Cell Signal (2014) ncbi
goat polyclonal (L-20)
  • WB; cow; 1:100; fig 5
Santa Cruz Biotechnology TNFR2 antibody (Santa Cruz Biotechnology, #sc-1074) was used in western blot on cow samples at 1:100 (fig 5). Biol Reprod (2014) ncbi
goat polyclonal (L-20)
  • ELISA; human
Santa Cruz Biotechnology TNFR2 antibody (Santa Cruz Biotechnology, sc-1074) was used in ELISA on human samples. Fitoterapia (2014) ncbi
goat polyclonal (L-20)
  • IC (knockout); mouse; 1:400; fig 1
Santa Cruz Biotechnology TNFR2 antibody (Santa, sc-1074) was used in immunocytochemistry (knockout) on mouse samples at 1:400 (fig 1). FASEB J (2012) ncbi
mouse monoclonal (D-2)
  • WB; human
Santa Cruz Biotechnology TNFR2 antibody (Santa Cruz Biotechnology, sc-8041) was used in western blot on human samples. Carcinogenesis (2009) ncbi
R and D Systems
mouse monoclonal (22210)
  • Neut; human
In order to study the impact of TNF-alpha and IL-1beta on the inflammatory phenotype of cancer-associated fibroblasts and mesenchymal stem/stromal cells, R and D Systems TNFR2 antibody (R&D Systems, MAB726) was used in neutralization on human samples. Stem Cell Res Ther (2015) ncbi
mouse monoclonal (22221)
  • Neut; human
R and D Systems TNFR2 antibody (R&D Systems, 22221) was used in neutralization on human samples. J Immunol (2014) ncbi
mouse monoclonal (22210)
  • IP; human
R&D Systems TNFR2 monoclonal antibody MAB726 was used in immunoprecipitation to study the Met-196 > Arg variation of human tumor necrosis factor receptor 2 (TNFR2)J Biol Chem (2005) ncbi
Invitrogen
not indicated
  • FC; human
Caltag PE-conjugated mouse MAb to TNFR2 (clone 4D1B10) was used in flow cytometry to study TNF alpha induced apoptosis of neonatal blood granulocytesPediatr Res (2005) ncbi
mouse monoclonal (897C2G9)
  • ELISA; human; 1 ug/ml; fig 4
In order to determine the role of TNFR2 in chronic inflammation-induced colonic epithelial alteration, Invitrogen TNFR2 antibody (Biosource, clone 897C2G9) was used in ELISA on human samples at 1 ug/ml (fig 4). Gastroenterology (2002) ncbi
Hycult Biotech
rabbit polyclonal
  • FC; human
  • IC; human; 1:100
In order to study the role of caspases in cytokine-induced barrier breakdown during neuroinflammation, Hycult Biotech TNFR2 antibody (Hycult, HP9003) was used in flow cytometry on human samples and in immunocytochemistry on human samples at 1:100. J Immunol (2012) ncbi
Abcam
mouse monoclonal (MR2-1)
  • IP; human
Abcam muse monoclonal antibody specific for TNFR2 (ab8161) was used in immunoprecipitation to study the Met-196 > Arg variation of human tumor necrosis factor receptor 2 (TNFR2)J Biol Chem (2005) ncbi
Enzo Life Sciences
not indicated
  • WB; human
Stressgen Bioreagents TNFR2 antibody was used in western blot in order to examine the physiological responses of human fetal retinal pigment epithelia (hfRPE) after polarized activation of proinflammatory cytokine receptors in vitroInvest Ophthalmol Vis Sci (2008) ncbi
not indicated
  • WB; human
Stressgen rabbit polyclonal IgG anti-TNFR2 was used in western blot to study the Met-196 > Arg variation of human tumor necrosis factor receptor 2 (TNFR2)J Biol Chem (2005) ncbi
Promega
rabbit polyclonal
  • IHC; mouse; 1 ug/ml
Promega TNFR2 antibody (Promega, G3231) was used in immunohistochemistry on mouse samples at 1 ug/ml. Mol Cell Neurosci (2015) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:200
Promega TNFR2 antibody (Promega, G3231) was used in immunohistochemistry - frozen section on mouse samples at 1:200. J Control Release (2015) ncbi
rabbit polyclonal
  • IHC; mouse; 1 ug/mL
Promega TNFR2 antibody (Promega, G3231) was used in immunohistochemistry on mouse samples at 1 ug/mL. J Comp Neurol (2015) ncbi
rabbit polyclonal
  • WB; mouse; 1:2000
Promega TNFR2 antibody (Promega, G3231) was used in western blot on mouse samples at 1:2000. PLoS ONE (2014) ncbi
rabbit polyclonal
  • IHC-F; rat
Promega TNFR2 antibody (Promega, G3231) was used in immunohistochemistry - frozen section on rat samples. J Comp Neurol (2008) ncbi
Cell Signaling Technology
rabbit polyclonal
  • WB; rat
  • IC; human
Cell Signaling Technology TNFR2 antibody (Cell Signaling, 3727) was used in western blot on rat samples and in immunocytochemistry on human samples. Toxicol Lett (2015) ncbi
BD Biosciences
rat monoclonal (hTNFR-M1)
  • FC; human
In order to determine the presence, frequency, association to other immune parameters, and functional properties of circulating CD14(+) cells lacking HLA-DR expression in patients with untreated chronic lymphocytic leukemia, BD Biosciences TNFR2 antibody (BD Bioscience, hTNFR-M1) was used in flow cytometry on human samples. Blood (2014) ncbi
Articles Reviewed
  1. Floria Lizarraga et al. (2015). "Tissue Inhibitor of Metalloproteinase-4 Triggers Apoptosis in Cervical Cancer Cells".PMID 26291714
  2. Li Zhang et al. (2015). "FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells".PMID 25939952
  3. Christina Katanov et al. (2015). "Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-α and the NF-κB pathway".PMID 25928089
  4. Choon Hee Chung et al. (2015). "Effects of Tumor Necrosis Factor-α on Podocyte Expression of Monocyte Chemoattractant Protein-1 and in Diabetic Nephropathy".PMID 25852733
  5. Lynnmaria Nazareth et al. (2015). "Differing phagocytic capacities of accessory and main olfactory ensheathing cells and the implication for olfactory glia transplantation therapies".PMID 25752729
  6. Aline M Thomas et al. (2015). "Sponge-mediated lentivirus delivery to acute and chronic spinal cord injuries".PMID 25724274
  7. E Przygrodzka et al. (2015). "Expression of factors associated with apoptosis in the porcine corpus luteum throughout the luteal phase of the estrous cycle and early pregnancy: their possible involvement in acquisition of luteolytic sensitivity".PMID 25457680
  8. Lynnmaria Nazareth et al. (2015). "Olfactory ensheathing cells are the main phagocytic cells that remove axon debris during early development of the olfactory system".PMID 25312022
  9. Nicola J Maney et al. (2014). "Dendritic cell maturation and survival are differentially regulated by TNFR1 and TNFR2".PMID 25288570
  10. Yuetong Ding et al. (2014). "Functional motor recovery from motoneuron axotomy is compromised in mice with defective corticospinal projections".PMID 25003601
  11. Regina Jitschin et al. (2014). "CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs".PMID 24850760
  12. Meiling Li et al. (2014). "Progranulin is required for proper ER stress response and inhibits ER stress-mediated apoptosis through TNFR2".PMID 24703938
  13. Ilona Kowalczyk-Zieba et al. (2014). "Influence of lysophosphatidic acid on nitric oxide-induced luteolysis in steroidogenic luteal cells in cows".PMID 24307705
  14. Wonhwa Lee et al. (2014). "Vascular barrier protective effects of pellitorine in LPS-induced inflammation in vitro and in vivo".PMID 24262867
  15. M Alejandro Lopez-Ramirez et al. (2012). "Role of caspases in cytokine-induced barrier breakdown in human brain endothelial cells".PMID 22896632
  16. Ping He et al. (2012). "Genetic deletion of TNF receptor suppresses excitatory synaptic transmission via reducing AMPA receptor synaptic localization in cortical neurons".PMID 21982949
  17. Audrey Luce et al. (2009). "Death receptor pathways mediate targeted and non-targeted effects of ionizing radiations in breast cancer cells".PMID 19126655
  18. Richa B Tripathi et al. (2008). "Chronically increased ciliary neurotrophic factor and fibroblast growth factor-2 expression after spinal contusion in rats".PMID 18615534
  19. Guangpu Shi et al. (2008). "Control of chemokine gradients by the retinal pigment epithelium".PMID 18450597
  20. Chieh An Liu et al. (2005). "Higher spontaneous and TNFalpha-induced apoptosis of neonatal blood granulocytes".PMID 15879291
  21. Andreas Till et al. (2005). "The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression".PMID 15572357
  22. Emiko Mizoguchi et al. (2002). "Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice".PMID 11781288