This is a review about TNFR1, based on 39 published articles (read how Labome selects the articles), using TNFR1 antibody in all methods. It is aimed to help Labome visitors find the most suited TNFR1 antibody.
TNFR1 synonym: CD120a; FPF; MS5; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR1-d2; TNFR55; TNFR60; p55; p55-R; p60; TNF-R1; TNF-RI; TNFR-I; tumor necrosis factor binding protein 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor-alpha receptor

Knockout validation
Abcamrabbit polyclonal
  • IC (knockout); mouse; 1:400; fig 1
Abcam TNFR1 antibody (ab19139, ab19139) was used in immunocytochemistry (knockout) on mouse samples at 1:400 (fig 1). FASEB J (2012) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-5)
  • IP; human
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz Biotechnology, sc-8436) was used in immunoprecipitation on human samples. Oncogene (2015) ncbi
mouse monoclonal (H398)
  • WB; human
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz, sc-52739) was used in western blot on human samples. J Biomed Sci (2015) ncbi
mouse monoclonal (H-5)
  • WB; human
In order to evaluate the effect of tumor necrosis factor on claudin-5 endothelial tight junction barriers, Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz Biotechnology, sc-8436) was used in western blot on human samples. PLoS ONE (2015) ncbi
mouse monoclonal (H-5)
  • WB; rat
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz, Sc-8436) was used in western blot on rat samples. Cell Biol Toxicol (2015) ncbi
mouse monoclonal (H-5)
  • WB; human
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz Biotechnology, SC-8436) was used in western blot on human samples. J Biol Chem (2015) ncbi
rabbit polyclonal (Ser 274)
  • IHC-P; human; 1:50
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz Biotechnology, sc-130220) was used in immunohistochemistry - paraffin section on human samples at 1:50. Oncol Lett (2015) ncbi
mouse monoclonal (H-5)
  • WB; rat; 1:100
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz Biotechnology, SC-8436) was used in western blot on rat samples at 1:100. Mol Vis (2014) ncbi
mouse monoclonal (H-5)
  • IP; mouse
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz Biotechnology, SC-8436) was used in immunoprecipitation on mouse samples. Cell Signal (2014) ncbi
rabbit polyclonal (H-271)
  • IHC; rat; 1:500
  • IC; rat; 1:500
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz Biotechnology, sc-7895) was used in immunohistochemistry on rat samples at 1:500 and in immunocytochemistry on rat samples at 1:500. PLoS ONE (2014) ncbi
goat polyclonal (G-20)
  • WB; mouse
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz Biotechnology, sc-1069) was used in western blot on mouse samples. Endocrinology (2014) ncbi
goat polyclonal (N-20)
  • WB; cow; 1:100; fig 5
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz Biotechnology, #sc-1067) was used in western blot on cow samples at 1:100 (fig 5). Biol Reprod (2014) ncbi
not indicated
  • WB; human
Santa Cruz anti-TNFR1 antibody was used to perform western blot in order to study the mechanism that TRAF2 inhibits stress-induced cell death.Cancer Res (2009) ncbi
mouse monoclonal (H-5)
  • WB; human
Santa Cruz Biotechnology TNFR1 antibody (Santa Cruz Biotechnology, sc-8436) was used in western blot on human samples. Carcinogenesis (2009) ncbi
not indicated
  • WB; human
  • IP; human
Santa Cruz Biotechnology anti-TNFR1 antibody was used to carry out western blot analysis and immunoprecipitation assays in order to investigate the role of TRAF2 phosphorylation on modulating TNF-a signaling.Mol Cell Biol (2009) ncbi
not indicated
  • WB; human
  • IP; human
Santa Cruz Biotechnology monoclonal anti-TNF-R1 antibody was used in western blot and immunoprecipitation to study the role for the binding of Triad3A with Hsp90 in regulating ubiquitination and proteasomal degradation of RIP1 in human embryonic kidney 293 cells.J Biol Chem (2006) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology anti-TNFR1 antibody was used in western blot to study the mechanism by which ER stress activates NF-kappaB and its role in regulation of ER stress-induced cell death in human cells.Mol Cell Biol (2006) ncbi
not indicated
  • IP; human
Santa Cruz mouse anti-TNFR1 antibody was used in immunoprecipitation to study PAK4 functions in hela cells.J Biol Chem (2005) ncbi
Abcam
rabbit polyclonal
  • WB; Domestic guinea pig; 1:1000
Abcam TNFR1 antibody (Abcam, ab19139) was used in western blot on Domestic guinea pig samples at 1:1000. Theriogenology (2015) ncbi
rabbit polyclonal
  • IHC-P; human; 1:300
Abcam TNFR1 antibody (Abcam, ab19139) was used in immunohistochemistry - paraffin section on human samples at 1:300. PLoS ONE (2014) ncbi
rabbit polyclonal
  • WB; human
Abcam TNFR1 antibody (Abcam, ab19139) was used in western blot on human samples. Antioxid Redox Signal (2014) ncbi
rabbit polyclonal
  • IHC; rat
Abcam TNFR1 antibody (Abcam, ab19139) was used in immunohistochemistry on rat samples. Hypertension (2013) ncbi
rabbit polyclonal
  • WB; human; 1:1000
Abcam TNFR1 antibody (Abcam, ab19139) was used in western blot on human samples at 1:1000. PLoS ONE (2013) ncbi
rabbit polyclonal
  • IC; human
Abcam TNFR1 antibody (Abcam, ab19139) was used in immunocytochemistry on human samples. FASEB J (2013) ncbi
rabbit polyclonal
  • WB; human
  • WB; mouse
Abcam TNFR1 antibody (Abcam, ab19139) was used in western blot on human samples and on mouse samples. Mol Cancer Res (2013) ncbi
rabbit polyclonal
  • IHC-P; rat; 1:1000
  • WB; rat; 1:1000
Abcam TNFR1 antibody (Abcam, ab19139) was used in immunohistochemistry - paraffin section on rat samples at 1:1000 and in western blot on rat samples at 1:1000. Exp Neurol (2013) ncbi
rabbit polyclonal
  • IHC; human
Abcam TNFR1 antibody (Abcam, ab107860) was used in immunohistochemistry on human samples. Cell Cycle (2013) ncbi
rabbit polyclonal
  • IC (knockout); mouse; 1:400; fig 1
Abcam TNFR1 antibody (ab19139, ab19139) was used in immunocytochemistry (knockout) on mouse samples at 1:400 (fig 1). FASEB J (2012) ncbi
R and D Systems
mouse monoclonal (16803)
  • Neut; human
In order to study the impact of TNF-alpha and IL-1beta on the inflammatory phenotype of cancer-associated fibroblasts and mesenchymal stem/stromal cells, R and D Systems TNFR1 antibody (R&D Systems, MAB225) was used in neutralization on human samples. Stem Cell Res Ther (2015) ncbi
goat polyclonal
  • WB; human
R and D Systems TNFR1 antibody (R&D Systems, AF225) was used in western blot on human samples. J Biol Chem (2015) ncbi
mouse monoclonal (16805)
  • WB; human; 1:250
R and D Systems TNFR1 antibody (R&D Systems, 16805) was used in western blot on human samples at 1:250. J Biol Chem (2012) ncbi
mouse monoclonal (16803)
  • IHC-P; human
R and D Systems TNFR1 antibody (R&D Systems, MAB225) was used in immunohistochemistry - paraffin section on human samples. Oncotarget (2012) ncbi
mouse monoclonal (16803)
  • FC; human
R and D Systems TNFR1 antibody (R & D Systems, FAB225P) was used in flow cytometry on human samples. Oncotarget (2012) ncbi
not indicated
  • WB; human
R&D Systems anti-TNFR1 antibody was used in human cells and in western blot to study the role for p21cip/waf1 and p27kip1 in TNF-alpha-induced inhibition of proliferation in human glioma cells.Mol Cancer (2007) ncbi
not indicated
  • IC; human
R&D Systems goat anti-TNF-R1 agonistic antibody was used in immunocytochemistry to study the combination of TAK1 with the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex which leading to NF-kappaB activation with MEKK3.J Biol Chem (2005) ncbi
not indicated
  • WB; human
R & D Systems goat polyclonal anti-TNFR1 antibody was used in western blot to detect TNFR1 in the PAK4 knockdown cells treated with TNFalpha+CHX.J Biol Chem (2005) ncbi
Hycult Biotech
mouse monoclonal (H398)
  • Neut; human
Hycult Biotech TNFR1 antibody (Hycult Biotech, H398) was used in neutralization on human samples. J Immunol (2014) ncbi
rabbit polyclonal
  • FC; human
  • IC; human; 1:100
In order to study the role of caspases in cytokine-induced barrier breakdown during neuroinflammation, Hycult Biotech TNFR1 antibody (Hycult, HP9002) was used in flow cytometry on human samples and in immunocytochemistry on human samples at 1:100. J Immunol (2012) ncbi
Enzo Life Sciences
not indicated
  • WB; human
Stressgen Bioreagents TNFR1 antibody was used in western blot in order to examine the physiological responses of human fetal retinal pigment epithelia (hfRPE) after polarized activation of proinflammatory cytokine receptors in vitroInvest Ophthalmol Vis Sci (2008) ncbi
Invitrogen
not indicated
  • FC; human
Caltag PE-conjugated mouse MAb to TNFR1 (clone 2H10) was used in flow cytometry to study TNF alpha induced apoptosis of neonatal blood granulocytesPediatr Res (2005) ncbi
Cell Signaling Technology
rabbit monoclonal (C25C1)
  • WB; human; fig 3
In order to test if atrazine induces DNA damage response-related proteins in normal human breast epithelial cells and study its cytotoxicity, Cell Signaling Technology TNFR1 antibody (Cell Signaling, 3736) was used in western blot on human samples (fig 3). Int J Mol Sci (2015) ncbi
rabbit monoclonal (C25C1)
  • IC; human
  • WB; rat
Cell Signaling Technology TNFR1 antibody (Cell Signaling, 3736) was used in immunocytochemistry on human samples and in western blot on rat samples. Toxicol Lett (2015) ncbi
rabbit monoclonal (C25C1)
  • WB; human
Cell Signaling Technology TNFR1 antibody (Cell Signaling, C25C1) was used in western blot on human samples. FASEB J (2013) ncbi
PeproTech
not indicatedPeprotech recombinant sTNFR was used to treat cells in order to study the role for IL-32 in the effect of IL-1 on endothelial cell functions.Proc Natl Acad Sci U S A (2009) ncbi
Articles Reviewed
  1. C K Lee et al. (2015). "Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death".PMID 26212014
  2. Chih Chung Lin et al. (2015). "Tumor necrosis factor-alpha induces VCAM-1-mediated inflammation via c-Src-dependent transactivation of EGF receptors in human cardiac fibroblasts".PMID 26173590
  3. Peixin Huang et al. (2015). "Atrazine Triggers DNA Damage Response and Induces DNA Double-Strand Breaks in MCF-10A Cells".PMID 26114388
  4. Li Zhang et al. (2015). "FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells".PMID 25939952
  5. Christina Katanov et al. (2015). "Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-α and the NF-κB pathway".PMID 25928089
  6. Paul R Clark et al. (2015). "Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases".PMID 25816133
  7. Caleigh M Opperman et al. (2015). "Tumor necrosis factor alpha stimulates p62 accumulation and enhances proteasome activity independently of ROS".PMID 25761618
  8. Yu Bo Wang et al. (2015). "Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling".PMID 25681446
  9. Millena Prata Jammal et al. (2015). "Immunohistochemical staining of tumor necrosis factor-α and interleukin-10 in benign and malignant ovarian neoplasms".PMID 25624918
  10. E Przygrodzka et al. (2015). "Expression of factors associated with apoptosis in the porcine corpus luteum throughout the luteal phase of the estrous cycle and early pregnancy: their possible involvement in acquisition of luteolytic sensitivity".PMID 25457680
  11. Sheng Gao et al. (2014). "Ischemia-reperfusion injury of the retina is linked to necroptosis via the ERK1/2-RIP3 pathway".PMID 25352744
  12. Nicola J Maney et al. (2014). "Dendritic cell maturation and survival are differentially regulated by TNFR1 and TNFR2".PMID 25288570
  13. Su Mi Lee et al. (2014). "Circulating TNF receptors are significant prognostic biomarkers for idiopathic membranous nephropathy".PMID 25098821
  14. Meiling Li et al. (2014). "Progranulin is required for proper ER stress response and inhibits ER stress-mediated apoptosis through TNFR2".PMID 24703938
  15. Ulisse Garbin et al. (2014). "Do oxidized polyunsaturated Fatty acids affect endoplasmic reticulum stress-induced apoptosis in human carotid plaques?".PMID 24597951
  16. YiYu Deng et al. (2014). "Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain".PMID 24498101
  17. Elangovan Vellaichamy et al. (2014). "Genetically altered mutant mouse models of guanylyl cyclase/natriuretic peptide receptor-A exhibit the cardiac expression of proinflammatory mediators in a gene-dose-dependent manner".PMID 24424043
  18. Ilona Kowalczyk-Zieba et al. (2014). "Influence of lysophosphatidic acid on nitric oxide-induced luteolysis in steroidogenic luteal cells in cows".PMID 24307705
  19. Shun Guang Wei et al. (2013). "Subfornical organ mediates sympathetic and hemodynamic responses to blood-borne proinflammatory cytokines".PMID 23670302
  20. Luke Gammon et al. (2013). "Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism".PMID 23638097
  21. Mei Chung Moh et al. (2013). "Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling".PMID 23620528
  22. Jinbo Han et al. (2013). "Nuclear expression of β-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells".PMID 23339186
  23. Marc S Weinberg et al. (2013). "Opposing actions of hippocampus TNFα receptors on limbic seizure susceptibility".PMID 23333565
  24. Mazhar Al-Zoubi et al. (2013). "Creating a tumor-resistant microenvironment: cell-mediated delivery of TNFα completely prevents breast cancer tumor formation in vivo".PMID 23292149
  25. Damien Destouches et al. (2012). "Multivalent pseudopeptides targeting cell surface nucleoproteins inhibit cancer cell invasion through tissue inhibitor of metalloproteinases 3 (TIMP-3) release".PMID 23109338
  26. Jun Jie Chen et al. (2012). "Mislocalization of death receptors correlates with cellular resistance to their cognate ligands in human breast cancer cells".PMID 22909995
  27. M Alejandro Lopez-Ramirez et al. (2012). "Role of caspases in cytokine-induced barrier breakdown in human brain endothelial cells".PMID 22896632
  28. Ping He et al. (2012). "Genetic deletion of TNF receptor suppresses excitatory synaptic transmission via reducing AMPA receptor synaptic localization in cortical neurons".PMID 21982949
  29. Gregory S Thomas et al. (2009). "Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation".PMID 19336568
  30. Claudia A Nold-Petry et al. (2009). "IL-32-dependent effects of IL-1beta on endothelial cell functions".PMID 19228941
  31. Audrey Luce et al. (2009). "Death receptor pathways mediate targeted and non-targeted effects of ionizing radiations in breast cancer cells".PMID 19126655
  32. Ken Blackwell et al. (2009). "TRAF2 phosphorylation modulates tumor necrosis factor alpha-induced gene expression and cell resistance to apoptosis".PMID 18981220
  33. Guangpu Shi et al. (2008). "Control of chemokine gradients by the retinal pigment epithelium".PMID 18450597
  34. Pabbisetty Sudheer Kumar et al. (2007). "Differential expression and role of p21cip/waf1 and p27kip1 in TNF-alpha-induced inhibition of proliferation in human glioma cells".PMID 17565690
  35. Colleen Fearns et al. (2006). "Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding".PMID 16968706
  36. Ping Hu et al. (2006). "Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression".PMID 16581782
  37. Marzenna Blonska et al. (2005). "TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation".PMID 16260783
  38. Xiaofan Li et al. (2005). "PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor".PMID 16227624
  39. Chieh An Liu et al. (2005). "Higher spontaneous and TNFalpha-induced apoptosis of neonatal blood granulocytes".PMID 15879291