This is a review about TGF-beta1, based on 28 published articles (read how Labome selects the articles), using TGF-beta1 antibody in all methods. It is aimed to help Labome visitors find the most suited TGF-beta1 antibody.
TGF-beta1 synonym: CED; DPD1; LAP; TGFB; TGFbeta; TGF-beta 1 protein; TGF-beta-1; latency-associated peptide; transforming growth factor beta-1

R and D SystemsR and D Systems TGF-beta1 product
  • block or activateIn 2008, Eric Huet et al. employed R and D Systems TGF-beta1 antibody to perform blocking experiment in order to study the role of CD147 promoted myofibroblast differentiation in tissue remodeling [ncbi , more ]. In 2005, Eun Ok Lee et al. utilized R and D Systems TGF-beta1 antibody to study matrix metalloproteinase-2 production in human monocytic THP-1 Cells [ncbi , more ]. In 2004, Yoshihide Asano et al. utilized R and D Systems TGF-beta1 antibody to study the impaired smad7-smurf mediated negative regulation of TGF- signaling in scleroderma fibroblasts [ncbi , more ]. Megan K Levings et al. employed R and D Systems TGF-beta1 antibody to determine TGF- levels in human T cell culture supernatants, and in blocking experiment to neutralize TGF- activity in CD4+ T cells, and R&D Systems biotinylated-chicken-polyclonal IgY anti-TGF- Ab was used in flow cytometry to detect membrane-bound TGF- in human CD4+ T cells [ncbi , more ] in 2002 and Susan Fanayan et al. used R and D Systems TGF-beta1 antibody to study a signaling pathway for IGFBP-3 from a cell surface receptor to nuclear transcriptional activity [ncbi , more ].
  • ELISAIn 2004, Medhat Shehata et al. utilized R and D Systems TGF-beta1 antibody to study the TGF- 1 induction of bone marrow reticulin fibrosis in hairy cell leukemia [ncbi , more ]. In 2003, Katrien Janssens et al. applied R and D Systems TGF-beta1 antibody to study the effect of transforming growth factor- 1 mutations on the action of TGF- 1 in vitro [ncbi , more ]. Dimitrios S Goumenos et al. applied R and D Systems TGF-beta1 antibody to study the site of synthesis and expression profile of TGF- 1 in the renal tissue of patients with heavy proteinuria and the relation of this expression with the urinary excretion of TGF- 1 [ncbi , more ] in 2002 and Megan K Levings et al. used R and D Systems TGF-beta1 antibody to determine TGF- levels in human T cell culture supernatants, and in blocking experiment to neutralize TGF- activity in CD4+ T cells, and R&D Systems biotinylated-chicken-polyclonal IgY anti-TGF- Ab was used in flow cytometry to detect membrane-bound TGF- in human CD4+ T cells [ncbi , more ].
  • flow cytometryIn 2002, Megan K Levings et al. employed R and D Systems TGF-beta1 antibody to determine TGF- levels in human T cell culture supernatants, and in blocking experiment to neutralize TGF- activity in CD4+ T cells, and R&D Systems biotinylated-chicken-polyclonal IgY anti-TGF- Ab was used in flow cytometry to detect membrane-bound TGF- in human CD4+ T cells [ncbi , more ].
  • immunohistochemistryIn 2003, Mohammed S Razzaque et al. employed R and D Systems TGF-beta1 antibody to stain for TGF-beta1 in conjunctival fibroblasts isolated from patients with OCP [ncbi , more ].
  • western blotKatrien Janssens et al. applied R and D Systems TGF-beta1 antibody to study the effect of transforming growth factor- 1 mutations on the action of TGF- 1 in vitro [ncbi , more ] in 2003 and Zenzo Isogai et al. used R and D Systems TGF-beta1 antibody to charaterize transforming growth factor beta-binding protein 1 [ncbi , more ].
Santa Cruz BiotechnologySanta Cruz Biotechnology TGF-beta1 product
  • immunocytochemistryIn 2008, Amber C Liu et al. used Santa Cruz Biotechnology TGF-beta1 antibody to investigate the regulatory role of transforming growth factor-beta in valve interstitial cell function during wound repair [ncbi , more ]. In 2004, Francesco Cipollone et al. employed Santa Cruz Biotechnology TGF-beta1 antibody to study the increased expression of transforming growth factor- 1 as a stabilizing factor in human atherosclerotic plaques [ncbi , more ].
  • immunohistochemistryIn 2009, Minghua Wu et al. utilized Santa Cruz Biotechnology TGF-beta1 antibody to investigate the role of PPAR-gamma in the regulation of bleomycin induced scleroderma [ncbi , more ]. In 2008, Xiao R Huang et al. utilized Santa Cruz Biotechnology TGF-beta1 antibody to demonstrate that mice expressed a latent form of TGF-beta1 in skin keratinocytes exhibited renoprotective effects on renal fibrosis in obstructive kidney disease [ncbi , more ]. In 2006, Nabeel Bardeesy et al. employed Santa Cruz Biotechnology TGF-beta1 antibody to perform western blot and immunohistochemistry assays in order to investigate the molecular regulation mechanisms of Smad4 in the process of normal pancreas development and pancreatic ductal adenocarcinomas (PDAC) growth [ncbi , more ]. In 2005, S Toyran et al. utilized Santa Cruz Biotechnology TGF-beta1 antibody to study the role of GDF-5 and BMP-7 in pathogenetic mechanisms of bone formation in the eye [ncbi , more ]. In 2004, Francesco Cipollone et al. employed Santa Cruz Biotechnology TGF-beta1 antibody to study the increased expression of transforming growth factor- 1 as a stabilizing factor in human atherosclerotic plaques [ncbi , more ]. In 2003, Julia I Leu et al. employed Santa Cruz Biotechnology TGF-beta1 antibody to study the massive hepatic apoptosis associated with TGF-beta1 activation after Fas ligand treatment of IGF binding protein-1-deficient mice [ncbi , more ]. In 2002, Dimitrios S Goumenos et al. applied Santa Cruz Biotechnology TGF-beta1 antibody to study the site of synthesis and expression profile of TGF- 1 in the renal tissue of patients with heavy proteinuria and the relation of this expression with the urinary excretion of TGF- 1 [ncbi , more ].
  • western blotNabeel Bardeesy et al. employed Santa Cruz Biotechnology TGF-beta1 antibody to perform western blot and immunohistochemistry assays in order to investigate the molecular regulation mechanisms of Smad4 in the process of normal pancreas development and pancreatic ductal adenocarcinomas (PDAC) growth [ncbi , more ] in 2006 and Grant Bledsoe et al. used Santa Cruz Biotechnology TGF-beta1 antibody to study the effects and potential mechanisms of kallikrein/kinin on inflammation and apoptosis induced by gentamicin [ncbi , more ]. In 2005, Ju Eun Oh et al. applied Santa Cruz Biotechnology TGF-beta1 antibody to study the beta-ig-h3-mediated keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha-3, beta-1, and the phosphatidylinositol 3-kinase/Akt signaling pathway (catalog: sc-146) [ncbi , more ]. In 2004, Francesco Cipollone et al. employed Santa Cruz Biotechnology TGF-beta1 antibody to study the increased expression of transforming growth factor- 1 as a stabilizing factor in human atherosclerotic plaques [ncbi , more ]. In 2003, Baozhi Yuan et al. employed Santa Cruz Biotechnology TGF-beta1 antibody to determine whether nonhypertensive elevations of plasma ANG II would modify the expression of genes involved in renal injury [ncbi , more ]. In 2002, Elizabeth Gore-Hyer et al. utilized Santa Cruz Biotechnology TGF-beta1 antibody to systematically compare the profibrogenic effects of CTGF and TGF-beta on human renal cells [ncbi , more ].
AbD SerotecAbD Serotec TGF-beta1 product
  • immunohistochemistryIn 2008, Lucia Kim et al. utilized AbD Serotec TGF-beta1 antibody to determine the pathogenic role of transforming growth factor-beta1 (TGF-beta1) in the mechanism of chronic rheumatic heart disease [ncbi , more ].
AbcamAbcam TGF-beta1 product
  • immunohistochemistryIn 2010, Katherine L Cook et al. applied Abcam TGF-beta1 antibody to perform immunohistochemistry in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors [ncbi , more ].
Cell Signaling Technology
  • western blotIn 2010, Katherine L Cook et al. applied Cell Signaling Technology TGF-beta1 antibody to perform western blot in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors [ncbi , more ].
Life Technologies Corporation
  • block or activateIn 2004, Medhat Shehata et al. utilized Life Technologies Corporation TGF-beta1 antibody to study the TGF- 1 induction of bone marrow reticulin fibrosis in hairy cell leukemia [ncbi , more ].
  • immunocytochemistryIn 2004, Medhat Shehata et al. utilized Life Technologies Corporation TGF-beta1 antibody to study the TGF- 1 induction of bone marrow reticulin fibrosis in hairy cell leukemia [ncbi , more ].
  • immunohistochemistryIn 2004, Medhat Shehata et al. utilized Life Technologies Corporation TGF-beta1 antibody to study the TGF- 1 induction of bone marrow reticulin fibrosis in hairy cell leukemia [ncbi , more ].
Sigma-AldrichSigma-Aldrich TGF-beta1 product
  • block or activateIn 2006, York Hunt Ng et al. employed Sigma-Aldrich TGF-beta1 antibody to study the differential effects of IL-1beta and TGF-beta1 on ADAMTS-1 expression in human decidual stromal cells [ncbi , more ].
  • western blotIn 2008, Sin Ae Lee et al. employed Sigma-Aldrich TGF-beta1 antibody to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis [ncbi , more ].
TECHNE
  • ELISAIn 2008, Michiyo Sasajima et al. applied TGF-beta1 antibody to study the mechanism of hair growth enhancement by t-flavanone in human cells [ncbi , more ].
CHATENOUD (INSERM)
  • flow cytometryIn 2004, Qizhi Tang et al. applied TGF-beta1 antibody to demonstrate a TGF-beta-independent role for CTLA-4 in Treg-mediated suppression in vitro [ncbi , more ].
ANITA ROBERTS (NATIONAL CANCER INSTITUTE)
  • immunohistochemistryIn 2004, Mario Schiffer et al. employed TGF-beta1 antibody to study the role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis [ncbi , more ].
GENZYME CO
  • ELISAIn 2002, Dimitrios S Goumenos et al. applied TGF-beta1 antibody to study the site of synthesis and expression profile of TGF- 1 in the renal tissue of patients with heavy proteinuria and the relation of this expression with the urinary excretion of TGF- 1 [ncbi , more ].
Promega
  • western blotIn 2003, Katrien Janssens et al. applied Promega TGF-beta1 antibody to study the effect of transforming growth factor- 1 mutations on the action of TGF- 1 in vitro [ncbi , more ].
Articles Reviewed
  1. Katherine L Cook et al. (2010). "Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors".PMID 20837666
  2. Minghua Wu et al. (2009). "Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma".PMID 19147827
  3. Amber C Liu et al. (2008). "Transforming growth factor-beta regulates in vitro heart valve repair by activated valve interstitial cells".PMID 18832581
  4. Xiao R Huang et al. (2008). "Mice overexpressing latent TGF-beta1 are protected against renal fibrosis in obstructive kidney disease".PMID 18448597
  5. Sin Ae Lee et al. (2008). "Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma".PMID 18357344
  6. Michiyo Sasajima et al. (2008). "trans-3,4'-Dimethyl-3-hydroxyflavanone, a hair growth enhancing active component, decreases active transforming growth factor beta2 (TGF-beta2) through control of urokinase-type plasminogen activator (uPA) on the surface of keratinocytes".PMID 18310908
  7. Lucia Kim et al. (2008). "Overexpression of transforming growth factor-beta 1 in the valvular fibrosis of chronic rheumatic heart disease".PMID 18303197
  8. Eric Huet et al. (2008). "Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling".PMID 17965264
  9. Nabeel Bardeesy et al. (2006). "Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer".PMID 17114584
  10. York Hunt Ng et al. (2006). "Differential effects of interleukin-1beta and transforming growth factor-beta1 on the expression of the inflammation-associated protein, ADAMTS-1, in human decidual stromal cells in vitro".PMID 16675485
  11. Grant Bledsoe et al. (2006). "Kallikrein/kinin protects against gentamicin-induced nephrotoxicity by inhibition of inflammation and apoptosis".PMID 16401625
  12. S Toyran et al. (2005). "Expression of growth differentiation factor-5 and bone morphogenic protein-7 in intraocular osseous metaplasia".PMID 15965172
  13. Ju Eun Oh et al. (2005). "Beta ig-h3 induces keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha3beta1 and the phosphatidylinositol 3-kinase/Akt signaling pathway".PMID 15805105
  14. Eun Ok Lee et al. (2005). "The amyloid-beta peptide suppresses transforming growth factor-beta1-induced matrix metalloproteinase-2 production via Smad7 expression in human monocytic THP-1 cells".PMID 15632190
  15. Qizhi Tang et al. (2004). "Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function".PMID 15468055
  16. Francesco Cipollone et al. (2004). "Increased expression of transforming growth factor-beta1 as a stabilizing factor in human atherosclerotic plaques".PMID 15297631
  17. Mario Schiffer et al. (2004). "A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis".PMID 15213232
  18. Medhat Shehata et al. (2004). "TGF-beta1 induces bone marrow reticulin fibrosis in hairy cell leukemia".PMID 14991065
  19. Yoshihide Asano et al. (2004). "Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts".PMID 14722617
  20. Baozhi Yuan et al. (2003). "Gene expression reveals vulnerability to oxidative stress and interstitial fibrosis of renal outer medulla to nonhypertensive elevations of ANG II".PMID 12676744
  21. Mohammed S Razzaque et al. (2003). "Role of collagen-binding heat shock protein 47 and transforming growth factor-beta1 in conjunctival scarring in ocular cicatricial pemphigoid".PMID 12657600
  22. Julia I Leu et al. (2003). "Massive hepatic apoptosis associated with TGF-beta1 activation after Fas ligand treatment of IGF binding protein-1-deficient mice".PMID 12511596
  23. Katrien Janssens et al. (2003). "Transforming growth factor-beta 1 mutations in Camurati-Engelmann disease lead to increased signaling by altering either activation or secretion of the mutant protein".PMID 12493741
  24. Dimitrios S Goumenos et al. (2002). "Transforming growth factor-beta(1) in the kidney and urine of patients with glomerular disease and proteinuria".PMID 12454225
  25. Megan K Levings et al. (2002). "Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells".PMID 12438424
  26. Zenzo Isogai et al. (2003). "Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein".PMID 12429738
  27. Elizabeth Gore-Hyer et al. (2002). "TGF-beta and CTGF have overlapping and distinct fibrogenic effects on human renal cells".PMID 12217862
  28. Susan Fanayan et al. (2002). "Signaling through the Smad pathway by insulin-like growth factor-binding protein-3 in breast cancer cells. Relationship to transforming growth factor-beta 1 signaling".PMID 11751851