This is a review about Smad3, based on 42 published articles (read how Labome selects the articles), using Smad3 antibody in experiments. It is aimed to help Labome visitors find the most suited Smad3 antibody.
Smad3 synonym: HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3; MAD homolog 3; MAD, mothers against decapentaplegic homolog 3; SMA- and MAD-related protein 3; SMAD, mothers against DPP homolog 3; hMAD-3; hSMAD3; mad homolog JV15-2; mad protein homolog; mad3; mothers against DPP homolog 3; mothers against decapentaplegic homolog 3

  • Upstate anti-Smad2/3 antibody was used for western blot to study the suppressing role of human FHL1 family members in the modulation of tumor cell growth through a TGF-beta like signaling pathway.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology14Smad3 antibody
    Life Technologies Corporation8Smad3 antibody
    EMD Millipore3Smad3 antibody
    Epitomics3
    R and D Systems1Smad3 antibody
    Abcam1Smad3 antibody
    Cell Signaling Technology7Smad3 antibody
    BD Biosciences2
    Source BioScience1
    Table 1. Smad3 antibody western blot.
  • Upstate mouse anti-Smad3(clone 2C12; catalog no. MAB10075; 1:50) antibody was used to perform immunohistochemistry and western blot in order to study the dynamical regulation of TGF-beta signaling during late lung development in the human and mouse.ncbi, more
  • Upstate Biotechnology rabbit anti-Smad3 antibody was used in human breast tumor cells (MDA-MB-231 cells) and in western blot, immunoprecipitation to study the effect of hyaluronan on the interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells.ncbi, more
  • R&D Systems rabbit anti-phospho Smad3 antibody was used for western blot in order to investigate the role of ALK5 in the regulation of pulmonary arterial hypertension.ncbi, more
Life Technologies CorporationLife Technologies Corporation Smad3 product
  • Zymed Smad3 polyclonal antibody was used in western blot in order to investigate the role of BMP9 signalling via ALK2/Smad1/Smad4 pathway in ovarian cancer.ncbi, more
  • Zymed anti-Smad3 antibody was used to perform immunohistochemistry in order to study the mechanism of the epithelial-mesenchymal transition in human mammary carcinoma cells induced by Six1 homeoprotein.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology2Smad3 antibody
    EMD Millipore1Smad3 antibody
    Life Technologies Corporation1Smad3 antibody
    Epitomics1
    Cell Signaling Technology1Smad3 antibody
    BD Biosciences1
    Table 2. Smad3 antibody immunohistochemistry.
  • Zymed Laboratories polyclonal anti-Smad3 antibody was used in western blot and immunocytochemistry to ascertain whether the downstream signaling pathways mediated by TGF-beta vary in different liver injury models.ncbi, more
  • Invitrogen/Zymed mouse monoclonal anti-Smad2 was used to perform western blot in order to show the mechanism that two functions of TGF become un-coupled during cancer development.ncbi, more
  • Zymed Laboratories antibody against SMAD3 was used in western blot to study the role for AP-1 in the induction of Smad7 expression by UV irradiation in human skin fibroblasts.ncbi, more
  • Zymed Laboratories Inc. anti-SMAD3 antibody catalog no. 51-1500 was used in cultured human cell lines and in western blot to study the effect of gadd45beta3' enhancer on SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor beta.ncbi, more
  • Zymed Laboratories SMAD3 antibody was used in western blot to demonstrate that SMAD2 and SMAD7 were involved in the post-translational regulation of Muc4.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology2Smad3 antibody
    Life Technologies Corporation1Smad3 antibody
    Epitomics1
    Cell Signaling Technology2Smad3 antibody
    Table 3. Smad3 antibody immunocytochemistry.
  • Zymed Lab 3 g/ml rabbit polyclonal Smad3 antibody was used in western blot to evaluate the presence and function of the family of the TGFbeta signaling molecules Smads during follicle development.ncbi, more
  • Zymed Laboratories Inc. anti-human Smad3 antibody (LPC3) was used in human T47D and MCF-7 cells and in immunoprecipitation and western blot to study a signaling pathway for IGFBP-3 from a cell surface receptor to nuclear transcriptional activity.ncbi, more
  • Abcam anti- phospho-Smad3 (p-Smad3) (ser433/435) antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis.ncbi, more
  • Santa Cruz Biotechnology Inc anti-p-Smad3 antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis.ncbi, more
  • Santa Cruz Biotechnology mouse anti-Smad3 antibody was used to carry out immunofluorescence assays in order to investigate the role for transforming growth factor beta in regulating neuronal cell development.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology2Smad3 antibody
    EMD Millipore1Smad3 antibody
    Life Technologies Corporation1Smad3 antibody
    BD Biosciences1
    Table 4. Smad3 antibody immunoprecipitation.
  • Santa Cruz Biotechnology anti-phospho-Smad2/3 (Ser 423/425) antibody was used for western blot to study the suppressing role of human FHL1 family members in the modulation of tumor cell growth through a TGF-beta like signaling pathway.ncbi, more
  • Santa Cruz Biotechnology anti-Smad3 antibody (sc-8332) was used in human LNCaP cells and in western blot to study the role of epidermal growth factor in transforming growth factor beta signaling and growth suppression.ncbi, more
  • Santa Cruz Biotechnology anti-Smad3 monoclonal antibody (FL-425) was used in western blot to detect Smad3 expression in COS7 cells.ncbi, more
  • Santa Cruz monoclonal Smad3 (I-20) antibody was used in western blot to study transcriptional repression of smad4ncbi, more
  • Santa Cruz Biotechnology anti-Smad2/3 and anti-Phospho-Smad2/3 antibodies were used in western blot to study chondrogenesis Induction by Smad3ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology1Smad3 antibody
    Table 5. Smad3 antibody EMSA.
  • Santa Cruz Biotechnology mouse anti-Smad1/2/3 (H-2) antibody was used in immunocytochemistry to study the role of internalization in transforming growth factor beta 1-induced smad2 association with smad anchor for receptor activation (SARA) and smad2-dependent signaling in human mesangial cellsncbi, more
  • Santa Cruz Biotechnology anti-Smad3 antibody was used in western blot to study apoptosis induceed through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells by activin receptor-like kinase-7.ncbi, more
  • Santa Cruz Smad3 antibody was used in western blot to study the pituitary prolactin expression and cell growth inhibited by activin.ncbi, more
  • Santa Cruz Biotechnology Inc antibody for Smad2/Smad3 was used in western blot to study the impaired Smad7-Smurf mediated negative regulation of TGF- signaling in scleroderma fibroblastsncbi, more
  • Santa Cruz Biotechnology anti-Smad3 polyclonal antibody was used in western blot to study transforming growth factor-beta signalingncbi, more
  • suppliernumreagent link
    Cell Signaling Technology1Smad3 antibody
    Table 6. Smad3 antibody flow cytometry.
  • Santa Cruz Biotechnology anti-phospho-Smad3 antibody was used in western blot to study that transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation.ncbi, more
  • Santa Cruz Biotechnology anti-Smad3 antibody was used in western blot to study the regulation of endoglin expression by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathwaysncbi, more
  • Santa Cruz anti-Smad3 antibody was used in EMSA to study the effect of transforming growth factor- 1 (TGF- 1) on human type II collagen gene expression in articular chondrocytes and the relationship of it with Sp3/Sp1 ratio.ncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal antibody against Smad3 was used in immunoprecipitation to examine the influence of transforming growth factor (TGF) 1 on proximal tubular epithelial cell-cell interaction, with particular emphasis on the regulation of adherens junction complex formation.ncbi, more
  • Santa Cruz Biotechnology mouse anti-Smad3 (H-2) antibody was used in western blot to study the role of Ets1 in the growth factor beta (TGF-beta) signaling pathway.ncbi, more
  • Santa Cruz Biotechnology Smads3 antibody was used in western blot and immunohistochemistry to demonstrate that alterations in the Smad pathway is responsible for TGF-beta hyperresponsiveness.ncbi, more
  • Santa Cruz Biotechnology Smad3 (FL-425) antibody was used in western blot and immunoprecipitation to study SnoN ubiquitination and degradationncbi, more
Epitomics
  • Epitomics anti-pSmad3 antibody (#1880) was used to perform immunohistochemistry assays in order to study the important role of TGF-beta signalling in blood-borne metastasis.ncbi, more
  • Epitomics anti-Smad3 antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis.ncbi, more
  • Epitomics Inc rabbit monoclonal anti-Smad3 antibody was used to carry out western blot analysis in order to investigate the roles for HMGA2 and Smads in the regulation of SNAIL1 expression during epithelial-mesenchymal transition.ncbi, more
  • Epitomics monoclonal anti-phospho-Smad3 antibody was used in western blot and immunocytochemistry to ascertain whether the downstream signaling pathways mediated by TGF-beta vary in different liver injury models.ncbi, more
  • Cell Signaling Technologies anti-SMAD3 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes.ncbi, more
  • Cell Signaling anti-p-Smad3 antibody was used to perform western blot in order to study the mechanism of the epithelial-mesenchymal transition in human mammary carcinoma cells induced by Six1 homeoprotein.ncbi, more
  • Cell Signaling Technology rabbit polyclonal Smad3 antibody was used to perform westn blot in order to investigate the relations between TGFbeta1 and TNFa.ncbi, more
  • Cell Signaling Technology rabbit anti-P-Smad3 antibody was used in western blot in order to demostrate that the target gene expression can be promoted through Smad2/3 activation.ncbi, more
  • Cell Signaling Technology mouse monoclonal anti-phospho-Smad3 antibody was used to carry out western blot analysis in order to investigate the roles for HMGA2 and Smads in the regulation of SNAIL1 expression during epithelial-mesenchymal transition.ncbi, more
  • Cell Signaling Technology monoclonal anti-phospho-Smad3 antibody was used in western blot and immunocytochemistry to ascertain whether the downstream signaling pathways mediated by TGF-beta vary in different liver injury models.ncbi, more
  • Cell Signaling rabbit polyclonal anti-pSmad3 was used to perform western blot in order to show the mechanism that two functions of TGF become un-coupled during cancer development.ncbi, more
  • Cell Signaling phospho-Smad3 antibody was used in immunohistochemistry to study the role of Alk3 during AV cushion morphogenesis in mouse embryonic hearts.ncbi, more
  • Cell Signaling anti-phospho Smad3 antibody (catalog number 9514) was used in human LNCaP cells and in western blot to study the role of epidermal growth factor in transforming growth factor beta signaling and growth suppression.ncbi, more
BD Biosciences
  • BD Biosciences Smad3 monoclonal antibody was used in western blot in order to investigate the role of BMP9 signalling via ALK2/Smad1/Smad4 pathway in ovarian cancer.ncbi, more
  • BD mouse monoclonal antibody against human and mouse Smad3 was used in immunohistochemistry to investigate the role of transforming growth factor Beta signaling in the regulation of tumor growth.ncbi, more
  • Transduction Laboratories anti-Smad3 antibody was used in western blot and immunoprecipitation to study Smad3 activation in the transforming growth factor beta signaling pathwayncbi, more
TEN DIJKE
  • Dr. Ten Dijke anti-phospho-Smad3 rabbit polyclonal antibody was used in western blot to study the role of TGF- signaling in the phosphorylation of Smad2 and Smad3.ncbi, more
Source BioScience
  • Autogen Bioclear goat anti-human Smad3 antibody was used in western blot to study TGF-beta1 signalingncbi, more
Articles Reviewed
  1. Ruth S Waterman et al. (2010). "A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype".PMID 20436665
  2. Blanca Herrera et al. (2009). "Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation".PMID 19996292
  3. Shinako Araki et al. (2010). "TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer".PMID 19955655
  4. Silvia Giampieri et al. (2009). "Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility".PMID 19838175
  5. Joanna Boros et al. (2009). "Overlapping promoter targeting by Elk-1 and other divergent ETS-domain transcription factor family members".PMID 19789270
  6. Douglas S Micalizzi et al. (2009). "The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling".PMID 19726885
  7. Akiyoshi Komuro et al. (2009). "Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling".PMID 19351925
  8. Xiaoying Liu et al. (2009). "Transforming growth factor beta1-mediated activation of the smooth muscle alpha-actin gene in human pulmonary myofibroblasts is inhibited by tumor necrosis factor-alpha via mitogen-activated protein kinase kinase 1-dependent induction of the Egr-1 transcr".PMID 19261809
  9. Marcela Guzman-Ayala et al. (2009). "Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells".PMID 19172185
  10. Chaoyang Jin et al. (2009). "Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness".PMID 19155312
  11. Lihua Ding et al. (2009). "Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway".PMID 19139564
  12. Matthew Thomas et al. (2009). "Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrot".PMID 19116361
  13. Sylvie Thuault et al. (2008). "HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition".PMID 18832382
  14. Al Karim Khimji et al. (2008). "Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation".PMID 18753413
  15. Savita Bharathy et al. (2008). "Cancer-associated transforming growth factor beta type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype".PMID 18339844
  16. Miguel A Alejandre-Alcázar et al. (2008). "TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs".PMID 18095342
  17. Lanying Song et al. (2007). "Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts".PMID 16959237
  18. Kyung Song et al. (2006). "Novel permissive role of epidermal growth factor in transforming growth factor beta (TGF-beta) signaling and growth suppression. Mediation by stabilization of TGF-beta receptor type II".PMID 16428382
  19. Yasuko Yamamura et al. (2006). "RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells".PMID 16373335
  20. Xiao Liang Zhang et al. (2005). "Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling".PMID 15661740
  21. Che Chang Chang et al. (2005). "Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4".PMID 15637079
  22. Takayuki Furumatsu et al. (2005). "Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment".PMID 15623506
  23. Constance E Runyan et al. (2005). "The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells".PMID 15613484
  24. Taihao Quan et al. (2005). "Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts".PMID 15579469
  25. Byung Chul Kim et al. (2004). "Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells".PMID 15107418
  26. Annie Lacerte et al. (2004). "Activin inhibits pituitary prolactin expression and cell growth through Smads, Pit-1 and menin".PMID 15031321
  27. Yoshihide Asano et al. (2004). "Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts".PMID 14722617
  28. Michael B Major et al. (2004). "Identification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor beta".PMID 14630914
  29. Kiyoshi Higashi et al. (2003). "Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3".PMID 12917425
  30. Celine Prunier et al. (2003). "The oncoprotein Ski acts as an antagonist of transforming growth factor-beta signaling by suppressing Smad2 phosphorylation".PMID 12732634
  31. Dirk Haller et al. (2003). "Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation".PMID 12672795
  32. Pedro Soto et al. (2003). "SMAD2 and SMAD7 involvement in the post-translational regulation of Muc4 via the transforming growth factor-beta and interferon-gamma pathways in rat mammary epithelial cells".PMID 12668667
  33. Tilman Sanchez-Elsner et al. (2002). "Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways".PMID 12228247
  34. Christos Chadjichristos et al. (2002). "Down-regulation of human type II collagen gene expression by transforming growth factor-beta 1 (TGF-beta 1) in articular chondrocytes involves SP3/SP1 ratio".PMID 12186868
  35. Lilly Y W Bourguignon et al. (2002). "Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells".PMID 12145287
  36. Jian Xu et al. (2002). "Stage-specific expression of Smad2 and Smad3 during folliculogenesis".PMID 12021033
  37. Ya Chung Tian et al. (2002). "Interaction between the transforming growth factor-beta type II receptor/Smad pathway and beta-catenin during transforming growth factor-beta1-mediated adherens junction disassembly".PMID 12000714
  38. Joanna Czuwara-Ladykowska et al. (2002). "Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signaling pathway and an antagonist of the profibrotic effects of TGF-beta".PMID 11919190
  39. Chunming Dong et al. (2002). "Deficient Smad7 expression: a putative molecular defect in scleroderma".PMID 11904440
  40. Susan Fanayan et al. (2002). "Signaling through the Smad pathway by insulin-like growth factor-binding protein-3 in breast cancer cells. Relationship to transforming growth factor-beta 1 signaling".PMID 11751851
  41. S L Stroschein et al. (2001). "Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN".PMID 11691834
  42. M Furuhashi et al. (2001). "Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway".PMID 11438668