This is a review about Smad1, based on 40 published articles (read how Labome selects the articles), using Smad1 antibody in all methods. It is aimed to help Labome visitors find the most suited Smad1 antibody.
Smad1 synonym: BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1; MAD, mothers against decapentaplegic homolog 1; Mad-related protein 1; SMAD, mothers against DPP homolog 1; TGF-beta signaling protein 1; mothers against DPP homolog 1; transforming growth factor-beta signaling protein 1

Santa Cruz Biotechnology
rabbit polyclonal (N-18)
  • IHC; human; fig 2
Santa Cruz Biotechnology Smad1 antibody (Santa Cruz, sc-6031-R) was used in immunohistochemistry on human samples (fig 2). PLoS ONE (2015) ncbi
rabbit polyclonal (N-18)
  • WB; human; 1:1000
In order to study endogenous activin A in human granulosa cells, Santa Cruz Biotechnology Smad1 antibody (Santa Cruz Biotechnology, sc-6031-R) was used in western blot on human samples at 1:1000. J Clin Endocrinol Metab (2015) ncbi
rabbit polyclonal (N-18)
  • WB; rat
Santa Cruz Biotechnology Smad1 antibody (Santa Cruz Biotechnology, sc-6031-R) was used in western blot on rat samples. Br J Pharmacol (2015) ncbi
mouse monoclonal (913C1b)
  • WB; rat
In order to study the effect of rosiglitazone treatment on the transforming growth factor-beta/SMAD signaling pathway in white adipose tissue of diabetic rats, Santa Cruz Biotechnology Smad1 antibody (Santa Cruz Biotechnology, sc-81378) was used in western blot on rat samples. Obesity (Silver Spring) (2014) ncbi
rabbit polyclonal (N-18)
  • ChIP; mouse
Santa Cruz Biotechnology Smad1 antibody (Santa Cruz, sc-6031 X) was used in chromatin immunoprecipitation on mouse samples. Development (2013) ncbi
mouse monoclonal (A-4)
  • WB; mouse
Santa Cruz Biotechnology Smad1 antibody (Santa Cruz Biotechnology, sc-7965) was used in western blot on mouse samples. J Am Soc Nephrol (2013) ncbi
not indicated
  • IC; human
Santa Cruz Biotechnology mouse anti-Smad1 antibody was used to carry out immunofluorescence assays in order to investigate the role for transforming growth factor beta in regulating neuronal cell development.Cereb Cortex (2010) ncbi
not indicated
  • WB; human
Santa Cruz anti-human Smad1 antibody was used to perform western blot in order to study the role of Smurf1 in TNF-induced systemic bone loss.J Biol Chem (2008) ncbi
not indicated
  • WB; human
Santa Cruz mouse monoclonal anti-Smad1 antibody was used in western blot to study endofin as a Smad anchor for receptor activation in BMP signalingJ Cell Sci (2007) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology SMAD antibody was used in western blot to demonstrate the opposing roles of distinct mammalian SWI/SNF chromatin remodeling complexes in cell-cycle control.EMBO J (2007) ncbi
not indicated
  • IC; human
Santa Cruz Biotechnology mouse anti-Smad1/2/3 (H-2) antibody was used in immunocytochemistry to study the role of internalization in transforming growth factor beta 1-induced smad2 association with smad anchor for receptor activation (SARA) and smad2-dependent signaling in human mesangial cellsJ Biol Chem (2005) ncbi
EMD Millipore
rabbit polyclonal
  • IHC-P; mouse; 1:100
EMD Millipore Smad1 antibody (Millipore, AB3848) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. Dev Biol (2014) ncbi
rabbit polyclonal
  • IHC; pig; 1:100
EMD Millipore Smad1 antibody (Millipore, AB3848) was used in immunohistochemistry on pig samples at 1:100. Dev Biol (2014) ncbi
rabbit polyclonal
  • IC; pig
EMD Millipore Smad1 antibody (Millipore, AB3848) was used in immunocytochemistry on pig samples. J Mol Cell Cardiol (2013) ncbi
rabbit polyclonal
  • WB; human; 1:500
  • WB; mouse; 1:500
EMD Millipore Smad1 antibody (Millipore, AB3848) was used in western blot on human samples at 1:500 and on mouse samples at 1:500. J Appl Oral Sci (2012) ncbi
mouse monoclonal (AS22)
  • WB; human; 1:500
  • WB; mouse; 1:500
EMD Millipore Smad1 antibody (Millipore, 05-1459) was used in western blot on human samples at 1:500 and on mouse samples at 1:500. J Appl Oral Sci (2012) ncbi
not indicated
  • WB; human
Upstate Biotechnology Smad1 polyclonal antibody was used in western blot in order to investigate the role of BMP9 signalling via ALK2/Smad1/Smad4 pathway in ovarian cancer.Cancer Res (2009) ncbi
not indicated
  • WB; human
Upstate anti-phospho-Smad1 (Ser463/465) antibody was used in western blot to study endofin as a Smad anchor for receptor activation in BMP signalingJ Cell Sci (2007) ncbi
Invitrogen
rabbit monoclonal (31H14L11)
  • WB; mouse; 1:200
In order to study kidney development in Robo2 mouse mutants, Invitrogen Smad1 antibody (Invitrogen, 700047) was used in western blot on mouse samples at 1:200. Dev Biol (2015) ncbi
rabbit polyclonal
  • IHC-P; human
In order to identify therapeutic targets for pediatric midline high-grade astrocytomas, Invitrogen Smad1 antibody (Invitrogen, 38-5400) was used in immunohistochemistry - paraffin section on human samples. Nat Genet (2014) ncbi
rabbit polyclonal
  • WB; human; fig 1
In order to study the relationship between bone morphogenetic protein and TGF-beta, Invitrogen Smad1 antibody (Life Technologies, 385400) was used in western blot on human samples (fig 1). Mol Cell Biol (2012) ncbi
not indicated
  • WB; human
Zymed Smad1 polyclonal antibody was used in western blot in order to investigate the role of BMP9 signalling via ALK2/Smad1/Smad4 pathway in ovarian cancer.Cancer Res (2009) ncbi
Abcam
rabbit polyclonal
  • WB; rat; 1:400
Abcam Smad1 antibody (Abcam, ab46688) was used in western blot on rat samples at 1:400. Mol Med Rep (2015) ncbi
not indicated
  • WB; human
Abcam SMAD1 was used for western blot in order to study the mechanism for PTEN regulation in glioma and further highlight dysregulation of Akt signaling as crucial to the development of these tumors.Genes Dev (2009) ncbi
Epitomics
not indicated
  • WB; human
Epitomics anti-Smad1 antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis.Cancer Res (2009) ncbi
Cell Signaling Technology
rabbit monoclonal (D59D7)
  • WB; human
In order to report that L3MBTL1 represses the ability of stem cells to drive hematopoietic-specific transcriptional programs via SMAD5 and impairing its recruitment to target regulatory regions, Cell Signaling Technology Smad1 antibody (Cell Signaling, 6944P) was used in western blot on human samples. Stem Cell Reports (2015) ncbi
rabbit monoclonal (D59D7)
  • WB; mouse; 1:1000
In order to study heart valve development and cardiac function in Galnt1 KO mice, Cell Signaling Technology Smad1 antibody (Cell Signaling, 6944) was used in western blot on mouse samples at 1:1000. PLoS ONE (2015) ncbi
rabbit polyclonal
  • WB; mouse
Cell Signaling Technology Smad1 antibody (Cell Signalling, 9743) was used in western blot on mouse samples. Stem Cells (2015) ncbi
rabbit polyclonal
  • WB; mouse
Cell Signaling Technology Smad1 antibody (Cell Signaling, 9743) was used in western blot on mouse samples. Biochim Biophys Acta (2015) ncbi
rabbit polyclonal
  • WB; rat; 1:500
Cell Signaling Technology Smad1 antibody (Cell Signaling, 9743) was used in western blot on rat samples at 1:500. Biochim Biophys Acta (2014) ncbi
rabbit polyclonal
  • WB; human; fig 1
Cell Signaling Technology Smad1 antibody (Cell Signaling Technology , 9743) was used in western blot on human samples (fig 1). FASEB J (2014) ncbi
rabbit polyclonal
  • WB; human; 1:1000
Cell Signaling Technology Smad1 antibody (Cell Signal, 9743) was used in western blot on human samples at 1:1000. Stem Cells Dev (2014) ncbi
rabbit monoclonal (D59D7)
  • WB; human; 1:1000
Cell Signaling Technology Smad1 antibody (Cell Signaling, 6944) was used in western blot on human samples at 1:1000. Nucleic Acids Res (2013) ncbi
rabbit monoclonal (D59D7)
  • WB; human; 1:2000
Cell Signaling Technology Smad1 antibody (Cell Signaling Technologies, 6944p) was used in western blot on human samples at 1:2000. PLoS ONE (2013) ncbi
rabbit polyclonal
  • WB; mouse
In order to study the role of endothelial-to-mesenchymal transition in the onset and progression of cerebral cavernous malformations, Cell Signaling Technology Smad1 antibody (Cell Signaling, 9743) was used in western blot on mouse samples. Nature (2013) ncbi
rabbit monoclonal (D59D7)
  • WB; common platanna
Cell Signaling Technology Smad1 antibody (Cell Signaling, 6944) was used in western blot on common platanna samples. Development (2013) ncbi
not indicated
  • WB; human
Cell Signaling Technology phospho-Smad1 (Ser463/465) polyclonal antibody was used in western blot in order to investigate the role of BMP9 signalling via ALK2/Smad1/Smad4 pathway in ovarian cancer.Cancer Res (2009) ncbi
not indicated
  • WB; human
Cell Signaling anti-p-Smad1 antibody was used to perform western blot in order to study the mechanism of the epithelial-mesenchymal transition in human mammary carcinoma cells induced by Six1 homeoprotein.J Clin Invest (2009) ncbi
not indicated
  • WB; human
Cell Signaling Technology anti-c-terminal-phosph-Smad1/5/8 antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis.Cancer Res (2009) ncbi
not indicated
  • WB; human
Cell Signaling anti-human pSmad1 antibody was used to perform western blot in order to study the role of Smurf1 in TNF-induced systemic bone loss.J Biol Chem (2008) ncbi
not indicated
  • WB; human
  • IC; human
Cell Signaling Technology anti-Smad1 antibody and anti-phospho-Smad1/5/8 antibody were used in western blot and western blot, immunocytochemistry to elucidate the anti-mitogenic effect of a proteasome inhibitor in relation to BMP signalling in colon cancer.Br J Pharmacol (2008) ncbi
not indicated
  • WB; human
Cell Signaling rabbit polyclonal anti-pSmad1 was used to perform western blot in order to show the mechanism that two functions of TGF become un-coupled during cancer development.Cancer Res (2008) ncbi
not indicated
  • WB; human
Cell Signaling Technologies anti-phospho-Smad-1 antibody was used in western blot to investigate SOSTDC1 expression in normal human kidney cells and clear cell renal carcinoma.Mol Biol Cell (2008) ncbi
not indicated
  • IHC; human
Cell Signaling phospho-Smad1 antibody was used in immunohistochemistry to study the role of Alk3 during AV cushion morphogenesis in mouse embryonic hearts.Dev Biol (2007) ncbi
not indicated
  • IHC; human
Cell Signaling Technology phospho-Smad-1 antibody was used in immunohistochemistry to study the mechanisms by which BMP signaling stimulates cellular differentiation during cartilage development.Proc Natl Acad Sci U S A (2005) ncbi
not indicated
  • WB; human
Cell Signaling Smad1 antibody was used in western blot to study GADD45 beta role during chondrocyte terminal differentiationJ Biol Chem (2005) ncbi
Articles Reviewed
  1. Elanor N Wainwright et al. (2015). "ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation".PMID 26116176
  2. Kira Young et al. (2015). "BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses".PMID 25909848
  3. Fabiana Perna et al. (2015). "The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells".PMID 25754204
  4. E Tian et al. (2015). "Galnt1 is required for normal heart valve development and cardiac function".PMID 25615642
  5. Hsun Ming Chang et al. (2015). "Recombinant BMP4 and BMP7 increase activin A production by up-regulating inhibin βA subunit and furin expression in human granulosa-lutein cells".PMID 25562508
  6. Federico Galvagni et al. (2015). "Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes".PMID 25504116
  7. Joohwee Kim et al. (2015). "Prostaglandin F2α receptor (FP) signaling regulates Bmp signaling and promotes chondrocyte differentiation".PMID 25499765
  8. Huading Lu et al. (2015). "Hepcidin promotes osteogenic differentiation through the bone morphogenetic protein 2/small mothers against decapentaplegic and mitogen-activated protein kinase/P38 signaling pathways in mesenchymal stem cells".PMID 25351366
  9. Yu Chun Wang et al. (2015). "Oestrogen inhibits BMP4-induced BMP4 expression in cardiomyocytes: a potential mechanism of oestrogen-mediated protection against cardiac hypertrophy".PMID 25323043
  10. Marie M Lockhart et al. (2014). "Alk3 mediated Bmp signaling controls the contribution of epicardially derived cells to the tissues of the atrioventricular junction".PMID 25300579
  11. Adam M Fontebasso et al. (2014). "Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma".PMID 24705250
  12. Marie Soleil Beaudoin et al. (2014). "Novel effects of rosiglitazone on SMAD2 and SMAD3 signaling in white adipose tissue of diabetic rats".PMID 24500776
  13. Erawan Borkham-Kamphorst et al. (2014). "The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling".PMID 24487063
  14. Griselda Valdez Magaña et al. (2014). "Paracrine effects of embryo-derived FGF4 and BMP4 during pig trophoblast elongation".PMID 24445281
  15. Alisha Holtzhausen et al. (2014). "Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development".PMID 24308972
  16. Nianhua Feng et al. (2014). "Generation of highly purified neural stem cells from human adipose-derived mesenchymal stem cells by Sox1 activation".PMID 24138016
  17. Yan Bai et al. (2013). "Bmp signaling represses Vegfa to promote outflow tract cushion development".PMID 23863481
  18. Pei Shan Hou et al. (2013). "LHX2 regulates the neural differentiation of human embryonic stem cells via transcriptional modulation of PAX6 and CER1".PMID 23804753
  19. Gang Ren et al. (2013). "The immunoglobulin superfamily protein differentiation of embryonic stem cells 1 (dies1) has a regulatory role in preadipocyte to adipocyte conversion".PMID 23799023
  20. Luigi Maddaluno et al. (2013). "EndMT contributes to the onset and progression of cerebral cavernous malformations".PMID 23748444
  21. Kevin Bosse et al. (2013). "Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease".PMID 23583836
  22. Abdul Soofi et al. (2013). "Kielin/chordin-like protein attenuates both acute and chronic renal injury".PMID 23539757
  23. Ariadne Cristiane Cabral Cruz et al. (2012). "Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells".PMID 23329244
  24. Chin Yan Lim et al. (2013). "Optimal histone H3 to linker histone H1 chromatin ratio is vital for mesodermal competence in Xenopus".PMID 23318639
  25. Eva Grönroos et al. (2012). "Transforming growth factor β inhibits bone morphogenetic protein-induced transcription through novel phosphorylated Smad1/5-Smad3 complexes".PMID 22615489
  26. Blanca Herrera et al. (2009). "Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation".PMID 19996292
  27. Douglas S Micalizzi et al. (2009). "The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling".PMID 19726885
  28. Tanja Vogel et al. (2010). "Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component".PMID 19587023
  29. Jason T Huse et al. (2009). "The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo".PMID 19487573
  30. Chaoyang Jin et al. (2009). "Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness".PMID 19155312
  31. Ruolin Guo et al. (2008). "Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins".PMID 18567580
  32. W K K Wu et al. (2008). "Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells".PMID 18414391
  33. Savita Bharathy et al. (2008). "Cancer-associated transforming growth factor beta type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype".PMID 18339844
  34. Kimberly Rose Blish et al. (2008). "A human bone morphogenetic protein antagonist is down-regulated in renal cancer".PMID 18032587
  35. Weibin Shi et al. (2007). "Endofin acts as a Smad anchor for receptor activation in BMP signaling".PMID 17356069
  36. Norman G Nagl et al. (2007). "Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control".PMID 17255939
  37. Lanying Song et al. (2007). "Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts".PMID 16959237
  38. Tatsuya Kobayashi et al. (2005). "BMP signaling stimulates cellular differentiation at multiple steps during cartilage development".PMID 16322106
  39. Kosei Ijiri et al. (2005). "A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation".PMID 16144844
  40. Constance E Runyan et al. (2005). "The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells".PMID 15613484