This is a review about SHP-2, based on 32 published articles (read how Labome selects the articles), using SHP-2 antibody in experiments. It is aimed to help Labome visitors find the most suited SHP-2 antibody.
SHP-2 synonym: BPTP3; CFC; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2; PTP-2C; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; tyrosine-protein phosphatase non-receptor type 11

  • Santa Cruz Biotechnology SHP2 antibody was used for western blot in order to investigate the role of phosphorylation-acetylation switch in the regulation of STAT1 signaling. (catalog: sc-7384) ncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology17SHP-2 antibodysc-7384
    EMD Millipore3SHP-2 antibody
    BD Biosciences10
    Cell Signaling Technology1SHP-2 antibody
    Table 1. SHP-2 antibody western blot.
  • Santa Cruz Biotechnology polyclonal anti-Shp2 antibody was used to perform western blot in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J.ncbi, more
  • Santa Cruz Biotechnology anti-SHP-2 polyclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation.ncbi, more
  • Santa Cruz Biotechnology SHP-2 antibody was used in western blot and immunoprecipitation to demonstrate that KLRG1 differentially regulates NK cell and T cell functions.ncbi, more
  • Santa Cruz anti-SHP-2 antibody was used in western blot to study the role of leukocyte-associated Ig-like receptor-1.ncbi, more
  • SCBT monoclonal Shp-2 antibody was used in western blot to investigate the induction of IL-8 by the Helicobacter pylori CagA proteinncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology5SHP-2 antibody
    EMD Millipore1SHP-2 antibody
    BD Biosciences3
    Cell Signaling Technology1SHP-2 antibody
    Table 2. SHP-2 antibody immunoprecipitation.
  • Santa Cruz Biotechnology SHP2 antibody was used in western blot and immunoprecipitation to show that the liver is a major site of the peripheral action of PTP1B in regulating glucose homeostasis.ncbi, more
  • Santa Cruz Biotechnology polyclonal anti-SHP-2 antibody (C-18) was used in western blot and immunoprecipitation to study regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus.ncbi, more
  • Santa Cruz Biotechnology SH-PTP2 / Shp2 (C-18) antibody was used in western blot to study a novel effector of fibroblast growth factor receptor 3 activationncbi, more
  • Santa Cruz Biotechnology mouse anti-SHP-2 antibody was used in immunocytochemistry to study the IL-2 production and proliferation in human T cells inhibited by the cell-cell adhesion molecule carcinoembryonic antigen-related cellular adhesion molecule 1.ncbi, more
  • Santa Cruz Biotechnology anti-SHP-2 antibody was used in immunocytochemistry to detect SHP-2 in HAECs with adenovirus infection and 293T cells with plasmid DNA transfection.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology1SHP-2 antibody
    Table 3. SHP-2 antibody immunocytochemistry.
  • Santa Cruz Biotechnology rabbit anti-SHP-2 antibody was used in western blot to study a potential role for tyrosine phosphatases.ncbi, more
  • Santa Cruz Biotechnology polyclonal SHP2 antibody was used in western blot to study the role of phosphoinositide 3-kinase beta lipid products in LPA-induced Ras activationncbi, more
  • Santa Cruz Biotechnology polyclonal anti-SHP-2 antibody was used in human HT-1080 cell and in immunoprecipitation to study the role for cell surface glycoprotein PZR in concanavalin A-induced cell signaling.ncbi, more
  • Santa Cruz Biotechnology anti-SHP-2 antibody was used in western blot to detect SHP-2 in the clonal lines of H-35 cells expressing G-CSFR-gp130 containing either 133 residues of the cytoplasmic domain of wild type gp130.ncbi, more
  • Santa Cruz Biotechnology rabbit anti-SHP-2 antibody was used in western blot and immunoprecipitation to study the T cell receptor signaling regulation by docking protein Gab2ncbi, more
  • Santa Cruz Biotechnology rabbit anti-SHP-2 polyclonal antibody was used in western blot to characterize SH2D1A missense mutations in X-linked lymphoproliferative disease patientsncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal Shp2 antibody was used in western blot to study Rap1 signaling activation in endosomes by nerve growth factorncbi, more
  • Santa Cruz Biotechnology anti-SHP2 monoclonal antibody was used in western blot to detect SHP-2 in U937 cells retrovirally infected with either empty vector or with Flag-tagged MIS.ncbi, more
  • Upstate SHP-2 antibody was used in western blot to study the association of ILT2 and murine MHC class I molecules in vivo.ncbi, more
  • Upstate Biotechnology anti-Shp-2 polyclonal antibody was used in western blot to study cells with mutant IGF-I receptor at tyrosines 1250 and 1251ncbi, more
  • Upstate Biotechnology anti-SHP-1 antibody was used in western blot and immunoprecipitation to study the T cell receptor signaling regulation by docking protein Gab2ncbi, more
  • Cell Signaling Technology anti-Shp2 (pY580) was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry.ncbi, more
  • Cell Signaling Technology rabbit anti-SHP2 (1:1000) and anti-phospho-SHP2 (Tyr 542) (1:1000) antibodies were used to perform to western blot and immunoprecipitation in order to study the role of ALK in the pathogenesis and the treatment of anaplastic large cell lymphoma.ncbi, more
BD Biosciences
  • BD Biosciences mouse anti-SHP-2 antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression.ncbi, more
  • BD Biosciences anti-Shp2 monoclonal antobody was used in western blot in order to study the function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clustersncbi, more
  • BD Transduction Labs anti-SHP-2 antibody was used in western blot to study positive and negative signaling by the natural killer cell receptor 2B4 (CD244).ncbi, more
  • BD Biosciences mouse anti-SHP-2 (clone 79) antibody was used in western blot to describe the identification and characterization of a myeloid inhibitory C-type lectin-like receptor (MICL) that is a negative regulator of granulocyte and monocyte function.ncbi, more
  • Transduction Laboratories anti-SHP-2 monoclonal antibody was used in western blot and immunoprecipitation to study the PTPH1 as a predominant protein-tyrosine phosphatase capable of interacting with and dephosphorylating the T cell receptor subunitncbi, more
  • BD Transduction Laboratories monoclonal anti-SHP-2 antibody was used in western blot to study the function for SHP-2 as a positive regulator of cytokine receptor signaling by regulating ubiquitination/degradation pathways.ncbi, more
  • Transduction Laboratories monoclonal anti-SHP-2 antibody was used in primary culture mesangial cells and in western blot to study the role for the interaction between G protein-coupled receptor and the phosphatase SHP-2 in bradykinin-induced inhibition of cell proliferation.ncbi, more
  • Transduction Laboratories monoclonal anti-SHP-2 antibody was used in western blot and immunoprecipitation to study the T cell receptor signaling regulation by docking protein Gab2ncbi, more
  • Transduction Laboratories mouse anti-SHP2 antibody was used in western blot and immunoprecipitation to study growth factor-specific signaling pathway stimulation and gene expression mediated by ErbB receptors.ncbi, more
  • Transduction Laboratories mouse monoclonal anti-Shp2 (PTP1D) antibody was used in western blot to study the effect of SNT1 on ERK activation and neuronal differentiation in PC12 cells.ncbi, more
Articles Reviewed
  1. Natalya N Pavlova et al. (2013). "A role for PVRL4-driven cell-cell interactions in tumorigenesis".PMID 23682311
  2. Sean C Bendall et al. (2011). "Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum".PMID 21551058
  3. Julia Foldi et al. (2010). "Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1".PMID 20870935
  4. Hyun Ju Kim et al. (2009). "The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo".PMID 19171907
  5. Oliver H Kramer et al. (2009). "A phosphorylation-acetylation switch regulates STAT1 signaling".PMID 19171783
  6. Francesco E Boccalatte et al. (2009). "The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL".PMID 18845790
  7. Yueping K Qian et al. (2008). "The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters".PMID 18647419
  8. Marlowe S Tessmer et al. (2007). "KLRG1 binds cadherins and preferentially associates with SHIP-1".PMID 17307799
  9. Siyuan Liang et al. (2006). "Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function".PMID 16897816
  10. Annelies Verbrugge et al. (2006). "Leukocyte-associated Ig-like receptor-1 has SH2 domain-containing phosphatase-independent function and recruits C-terminal Src kinase".PMID 16380958
  11. Sabine Brandt et al. (2005). "NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein".PMID 15972330
  12. Philipp Eissmann et al. (2005). "Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244)".PMID 15713798
  13. Fawaz G Haj et al. (2005). "Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice".PMID 15699041
  14. Patrick A Kiely et al. (2005). "RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251".PMID 15611085
  15. Matthew L Jones et al. (2004). "Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus".PMID 15269224
  16. April N Meyer et al. (2004). "The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation".PMID 15105428
  17. Charng Jui Chen et al. (2004). "The cell-cell adhesion molecule carcinoembryonic antigen-related cellular adhesion molecule 1 inhibits IL-2 production and proliferation in human T cells by association with Src homology protein-1 and down-regulates IL-2 receptor".PMID 15004155
  18. Andrew S J Marshall et al. (2004). "Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes".PMID 14739280
  19. Margaret S Sozio et al. (2004). "PTPH1 is a predominant protein-tyrosine phosphatase capable of interacting with and dephosphorylating the T cell receptor zeta subunit".PMID 14672952
  20. Samir Ali et al. (2003). "SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor".PMID 14522994
  21. Naoko Kogata et al. (2003). "Identification of Fer tyrosine kinase localized on microtubules as a platelet endothelial cell adhesion molecule-1 phosphorylating kinase in vascular endothelial cells".PMID 12972546
  22. Johan Duchene et al. (2002). "A novel protein-protein interaction between a G protein-coupled receptor and the phosphatase SHP-2 is involved in bradykinin-induced inhibition of cell proliferation".PMID 12177051
  23. Christine Guntermann et al. (2002). "CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases".PMID 11970985
  24. Armelle Yart et al. (2002). "A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid".PMID 11916960
  25. Runxiang Zhao et al. (2002). "Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling".PMID 11751924
  26. F Blanchard et al. (2001). "Oncostatin M regulates the synthesis and turnover of gp130, leukemia inhibitory factor receptor alpha, and oncostatin M receptor beta by distinct mechanisms".PMID 11602599
  27. S Yamasaki et al. (2001). "Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules".PMID 11572860
  28. M Morra et al. (2001). "Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients".PMID 11477068
  29. C Wu et al. (2001). "Nerve growth factor activates persistent Rap1 signaling in endosomes".PMID 11466412
  30. C Sweeney et al. (2001). "Growth factor-specific signaling pathway stimulation and gene expression mediated by ErbB receptors".PMID 11297548
  31. T Ulyanova et al. (2001). "Molecular cloning of MIS, a myeloid inhibitory siglec, that binds protein-tyrosine phosphatases SHP-1 and SHP-2".PMID 11278955
  32. H Xu et al. (2001). "Multiple effector domains within SNT1 coordinate ERK activation and neuronal differentiation of PC12 cells".PMID 11278583