This is a review about Plk1, based on 25 published articles (read how Labome selects the articles), using Plk1 antibody in all methods. It is aimed to help Labome visitors find the most suited Plk1 antibody.
Plk1 synonym: PLK; STPK13; PLK-1; cell cycle regulated protein kinase; polo (Drosophia)-like kinase; polo like kinase; serine/threonine-protein kinase 13; serine/threonine-protein kinase PLK1

Santa Cruz BiotechnologySanta Cruz Biotechnology Plk1 product
  • immunocytochemistryIn 2010, Lori Jo Wilmeth et al. applied Santa Cruz Biotechnology Plk1 antibody to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis [ncbi , more ].
  • immunohistochemistryIn 2005, Il Man Kim et al. applied Santa Cruz Biotechnology Plk1 antibody to study the role of forkhead box m1 transcription factor in embryonic development of pulmonary vasculature [ncbi , more ].
  • immunoprecipitationIn 2010, Hyungshin Yim et al. employed Santa Cruz Biotechnology Plk1 antibody to perform immunoprecipitation in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase [ncbi , more ]. In 2008, Tomoyasu Higashimoto et al. employed Santa Cruz Biotechnology Plk1 antibody to perform immunoprecipitation in order to study the funtion of phosphorylation of gamma-binding domain of IkB kinase beta [ncbi , more ]. In 2005, Wei Zhang et al. utilized Santa Cruz Biotechnology Plk1 antibody to detect Plk1 in U2OS cells transfected with wt, K82R, or T210D Plk1 plasmids or GFP-Nek2A-U2OS cells treated with siRNA against Plk1 [ncbi , more ].
  • western blotIn 2009, DaMing Gao et al. applied Santa Cruz Biotechnology Plk1 antibody to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction (catalog: SC-17783) [ncbi , more ]. Santa Cruz Biotechnology Plk1 antibody was used in 2005 to detect Plk1 in U2OS cells transfected with wt, K82R, or T210D Plk1 plasmids or GFP-Nek2A-U2OS cells treated with siRNA against Plk1 [ncbi , more ], to study heat shock transcription factor 1 phosphorylation and translocation during heat stress [ncbi , more ]and to study the function of forkhead box M1 to regulate the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase [ncbi , more ]. In 2004, Yutaka Masuda et al. utilized Santa Cruz Biotechnology Plk1 antibody to study the involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis which was induced by beta-hydroxyisovalerylshikonin [ncbi , more ].
EMD MilliporeEMD Millipore Plk1 product
  • immunocytochemistryHyungshin Yim et al. employed EMD Millipore Plk1 antibody to perform immunocytochemistry in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase [ncbi , more ] in 2010 and Conrad von Schubert et al. used EMD Millipore Plk1 antibody to perform western blot and immunofluorescence in order to study the parasite Theileria involved host cell mitotic and central spindles machinery [ncbi , more ]. In 2003, Alison J Faragher et al. used EMD Millipore Plk1 antibody to study the effect of Nek2A kinase on centrosome disjunction which is required for formation of bipolar mitotic spindles [ncbi , more ].
  • western blotIn 2010, Conrad von Schubert et al. used EMD Millipore Plk1 antibody to perform western blot and immunofluorescence in order to study the parasite Theileria involved host cell mitotic and central spindles machinery [ncbi , more ]. Mark W Jackson et al. utilized EMD Millipore Plk1 antibody to study p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2 [ncbi , more ] in 2005 and Pascale Monzo et al. used EMD Millipore Plk1 antibody to present several clues for the involvement of CD2AP in cytokinesis [ncbi , more ].
Life Technologies CorporationLife Technologies Corporation Plk1 product
  • immunocytochemistryJonathan P Aumais et al. employed Life Technologies Corporation Plk1 antibody to detect Plk1 in HeLa cells transfected with Luc siRNA or NudC siRNA [ncbi , more ] in 2003 and Lyuben Tsvetkov et al. used Life Technologies Corporation Plk1 antibody to study Plk1 in 293 and U2OS cells [ncbi , more ].
  • immunoprecipitationIn 2004, Xiaoqi Liu et al. employed Life Technologies Corporation Plk1 antibody to study the interactions of polo-like-kinase 1 with the mitotic kinesin-like protein CHO1/MKLP-1 [ncbi , more ]. Horng Ru Lin et al. used Life Technologies Corporation Plk1 antibody to the dissociation of the BRCA2-P/CAF complex [ncbi , more ] in 2003 and Lyuben Tsvetkov et al. used Life Technologies Corporation Plk1 antibody to study Plk1 in 293 and U2OS cells [ncbi , more ]. In 2001, Y Feng et al. applied Life Technologies Corporation Plk1 antibody to study the interaction of polo-like kinase (Plk) with proteasomes and its role as a important mitotic regulator of proteasome activity [ncbi , more ].
  • western blotIn 2009, Younghoon Kee et al. applied Life Technologies Corporation Plk1 antibody to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis [ncbi , more ]. Tomoyasu Higashimoto et al. applied Life Technologies Corporation Plk1 antibody to perform western blot in order to study the funtion of phosphorylation of gamma-binding domain of IkB kinase beta [ncbi , more ] in 2008 and Shigeko Yamashiro et al. used Life Technologies Corporation Plk1 antibody to carry out western blot analysis in order to investigate the role for MYPT1 in regulating mitosis by antagonizing PLK1 [ncbi , more ]. In 2005, Krystyna Mazan-Mamczarz et al. applied Life Technologies Corporation Plk1 antibody to study the en masse changes in translation in human carcinoma cells exposed to short-wavelength ultraviolet light (UVC) [ncbi , more ]. Jonathan P Aumais et al. employed Life Technologies Corporation Plk1 antibody to detect Plk1 in HeLa cells transfected with Luc siRNA or NudC siRNA [ncbi , more ] in 2003 and Lyuben Tsvetkov et al. used Life Technologies Corporation Plk1 antibody to study Plk1 in 293 and U2OS cells [ncbi , more ]. In 2002, Dongmin Kang et al. utilized Life Technologies Corporation Plk1 antibody to study the effect of checkpoint protein Chfr on Plk1 and Cdc2 at the G2 to M transition [ncbi , more ]. In 2001, Y Feng et al. applied Life Technologies Corporation Plk1 antibody to study the interaction of polo-like kinase (Plk) with proteasomes and its role as a important mitotic regulator of proteasome activity [ncbi , more ].
AbcamAbcam Plk1 product
  • immunohistochemistryIn 2008, Rekha Rai et al. employed Abcam Plk1 antibody to perform immunohistochemistry in order to study the functions of MDC1 and BRIT1 in the centrosome maturation and spindle assembly [ncbi , more ].
Bethyl
  • immunoprecipitationIn 2008, Shigeko Yamashiro et al. utilized Bethyl Plk1 antibody to carry out immunoprecipitation assays in order to investigate the role for MYPT1 in regulating mitosis by antagonizing PLK1 [ncbi , more ].
BD Biosciences
  • immunocytochemistryIn 2008, Shigeko Yamashiro et al. used BD Biosciences Plk1 antibody to carry out western blot analysis and immunofluorescence assays in order to investigate the role for MYPT1 in regulating mitosis by antagonizing PLK1 [ncbi , more ].
  • western blotIn 2008, Shigeko Yamashiro et al. used BD Biosciences Plk1 antibody to carry out western blot analysis and immunofluorescence assays in order to investigate the role for MYPT1 in regulating mitosis by antagonizing PLK1 [ncbi , more ].
LEANA M TOPPER
  • western blotIn 2002, Leana M Topper et al. utilized Plk1 antibody to study the role of dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrating on kinetochores and chromosome arms in mitosis [ncbi , more ].
INIVTROGEN
  • immunoprecipitationIn 2006, Aristotelis Astrinidis et al. applied Plk1 antibody to study the interaction of hamartin with polo-like kinase 1 in human cells [ncbi , more ].
  • western blotIn 2006, Aristotelis Astrinidis et al. applied Plk1 antibody to study the interaction of hamartin with polo-like kinase 1 in human cells [ncbi , more ].
Articles Reviewed
  1. Hyungshin Yim et al. (2010). "Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase".PMID 21041660
  2. Conrad von Schubert et al. (2010). "The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells".PMID 20927361
  3. Lori Jo Wilmeth et al. (2010). "Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis".PMID 19955215
  4. DaMing Gao et al. (2009). "Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction".PMID 19270695
  5. Younghoon Kee et al. (2009). "Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis".PMID 19270156
  6. Tomoyasu Higashimoto et al. (2008). "Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1".PMID 18957422
  7. Rekha Rai et al. (2008). "Differential regulation of centrosome integrity by DNA damage response proteins".PMID 18635967
  8. Shigeko Yamashiro et al. (2008). "Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1".PMID 18477460
  9. Aristotelis Astrinidis et al. (2006). "Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner".PMID 16339216
  10. I Ching Wang et al. (2005). "Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase".PMID 16314512
  11. Wei Zhang et al. (2005). "The role of Polo-like kinase 1 in the inhibition of centrosome separation after ionizing radiation".PMID 16157594
  12. Krystyna Mazan-Mamczarz et al. (2005). "En masse analysis of nascent translation using microarrays".PMID 16060370
  13. Mark W Jackson et al. (2005). "p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2".PMID 15827088
  14. Il Man Kim et al. (2005). "The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature".PMID 15817462
  15. Pascale Monzo et al. (2005). "Clues to CD2-associated protein involvement in cytokinesis".PMID 15800069
  16. Soo A Kim et al. (2005). "Polo-like kinase 1 phosphorylates heat shock transcription factor 1 and mediates its nuclear translocation during heat stress".PMID 15661742
  17. Yutaka Masuda et al. (2004). "Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin".PMID 15292218
  18. Xiaoqi Liu et al. (2004). "Molecular interactions of Polo-like-kinase 1 with the mitotic kinesin-like protein CHO1/MKLP-1".PMID 15199097
  19. Alison J Faragher et al. (2003). "Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles".PMID 12857871
  20. Horng Ru Lin et al. (2003). "M phase-specific phosphorylation of BRCA2 by Polo-like kinase 1 correlates with the dissociation of the BRCA2-P/CAF complex".PMID 12815053
  21. Jonathan P Aumais et al. (2003). "Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis".PMID 12679384
  22. Lyuben Tsvetkov et al. (2003). "Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody".PMID 12493754
  23. Leana M Topper et al. (2002). "The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis".PMID 12429948
  24. Dongmin Kang et al. (2002). "The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition".PMID 11807090
  25. Y Feng et al. (2001). "Polo-like kinase interacts with proteasomes and regulates their activity".PMID 11205743